Research Topics
Species | Yi Ping RongSummaryAffiliation: Case Western Reserve University Country: USA Publications
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Detail Information
Publications
Apoptosis inhibition by Bcl-2 gives way to autophagy in glucocorticoid-treated lymphocytesSarah Swerdlow
Department of Medicine, Comprehensive Cancer Center, Case Western Reserve University and University Hospitals of Cleveland, Cleveland, Ohio 44106, USA
Autophagy 4:612-20. 2008....
Bcl-2 protein family members: versatile regulators of calcium signaling in cell survival and apoptosisYiping Rong
Department of Medicine and Pharmacology, Comprehensive Cancer Center and University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH 44106, USA
Annu Rev Physiol 70:73-91. 2008....
Targeting Bcl-2 based on the interaction of its BH4 domain with the inositol 1,4,5-trisphosphate receptorYi Ping Rong
Department of Medicine, Comprehensive Cancer Center and University Hospital of Cleveland, Case Western Reserve University, Cleveland, OH 44106, USA
Biochim Biophys Acta 1793:971-8. 2009..In addition, we speculate on how the BH4 domain of Bcl-2 can be targeted therapeutically not only for diseases associated with apoptosis resistance, but also for diseases associated with accelerated cell death...
Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signalsYi Ping Rong
Department of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA
Mol Cell 31:255-65. 2008....
Induction of Ca²+-driven apoptosis in chronic lymphocytic leukemia cells by peptide-mediated disruption of Bcl-2-IP3 receptor interactionFei Zhong
Department of Medicine and Pharmacology, Case Western Reserve University School of Medicine, Case Comprehensive Cancer Center, and University Hospitals Case Medical Center, Cleveland, OH, USA
Blood 117:2924-34. 2011....
The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptorYi Ping Rong
Departments of Medicine and Pharmacology, Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH 44106, USA
Proc Natl Acad Sci U S A 106:14397-402. 2009..By inhibiting proapoptotic Ca(2+) signals at their point of origin, the Bcl-2 BH4 domain has the facility to block diverse pathways through which Ca(2+) induces apoptosis...
