Rod K Nibbe

Summary

Affiliation: Case Western Reserve University
Country: USA

Publications

  1. pmc Discovery and scoring of protein interaction subnetworks discriminative of late stage human colon cancer
    Rod K Nibbe
    Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Mol Cell Proteomics 8:827-45. 2009
  2. pmc An integrative -omics approach to identify functional sub-networks in human colorectal cancer
    Rod K Nibbe
    Center for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, Ohio, United States of America
    PLoS Comput Biol 6:e1000639. 2010
  3. doi request reprint Protein-protein interaction networks and subnetworks in the biology of disease
    Rod K Nibbe
    Center for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, OH, USA
    Wiley Interdiscip Rev Syst Biol Med 3:357-67. 2011
  4. pmc Identifying stage-specific protein subnetworks for colorectal cancer
    Sinan Erten
    Department of Electrical Engineering and Computer Science, Case Western Reserve University, Cleveland, OH, USA
    BMC Proc 6:S1. 2012
  5. pmc Subnetwork state functions define dysregulated subnetworks in cancer
    Salim A Chowdhury
    Department of Electrical Engineering and Computer Science, Case Western Reserve University, Cleveland, Ohio, USA
    J Comput Biol 18:263-81. 2011

Detail Information

Publications5

  1. pmc Discovery and scoring of protein interaction subnetworks discriminative of late stage human colon cancer
    Rod K Nibbe
    Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Mol Cell Proteomics 8:827-45. 2009
    ..Overall the method outlines a quantitative approach for integrating proteomics data, gene expression data, and the wealth of accumulated legacy experimental data to discover significant protein subnetworks specific to disease...
  2. pmc An integrative -omics approach to identify functional sub-networks in human colorectal cancer
    Rod K Nibbe
    Center for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, Ohio, United States of America
    PLoS Comput Biol 6:e1000639. 2010
    ..Cross-classification experiments to predict disease class show excellent performance using only a few sub-networks, underwriting the strength of the proposed approach in discovering relevant and reproducible sub-networks...
  3. doi request reprint Protein-protein interaction networks and subnetworks in the biology of disease
    Rod K Nibbe
    Center for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, OH, USA
    Wiley Interdiscip Rev Syst Biol Med 3:357-67. 2011
    ....
  4. pmc Identifying stage-specific protein subnetworks for colorectal cancer
    Sinan Erten
    Department of Electrical Engineering and Computer Science, Case Western Reserve University, Cleveland, OH, USA
    BMC Proc 6:S1. 2012
    ..These algorithms use protein-protein interaction (PPI) networks as an integrative framework and identify subnetworks that are coordinately dysregulated in the phenotype of interest...
  5. pmc Subnetwork state functions define dysregulated subnetworks in cancer
    Salim A Chowdhury
    Department of Electrical Engineering and Computer Science, Case Western Reserve University, Cleveland, Ohio, USA
    J Comput Biol 18:263-81. 2011
    ..Comprehensive cross-classification experiments show that subnetworks identified by Crane outperform those identified by additive algorithms in predicting metastasis of colorectal cancer (CRC)...