Liem Nguyen

Summary

Affiliation: Case Western Reserve University
Country: USA

Publications

  1. ncbi Mycobacterial subversion of chemotherapeutic reagents and host defense tactics: challenges in tuberculosis drug development
    Liem Nguyen
    Department of Molecular Biology and Microbiology, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Annu Rev Pharmacol Toxicol 49:427-53. 2009
  2. ncbi Protein kinase G is required for intrinsic antibiotic resistance in mycobacteria
    Kerstin A Wolff
    Department of Molecular Biology and Microbiology, Case Western Reserve University, School of Medicine, Wood Building, 10900 Euclid Avenue, Cleveland, OH 44106 4960, USA
    Antimicrob Agents Chemother 53:3515-9. 2009
  3. ncbi A lipoprotein modulates activity of the MtrAB two-component system to provide intrinsic multidrug resistance, cytokinetic control and cell wall homeostasis in Mycobacterium
    Hoa T Nguyen
    Department of Molecular Biology and Microbiology, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Mol Microbiol 76:348-64. 2010

Collaborators

  • Jean Pieters
  • Hoa T Nguyen
  • Kerstin A Wolff
  • Sam Ogwang
  • Richard H Cartabuke
  • Ajay Singh

Detail Information

Publications3

  1. ncbi Mycobacterial subversion of chemotherapeutic reagents and host defense tactics: challenges in tuberculosis drug development
    Liem Nguyen
    Department of Molecular Biology and Microbiology, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Annu Rev Pharmacol Toxicol 49:427-53. 2009
    ..tuberculosis. This knowledge may help to reveal current targets for the development of novel antituberculosis drugs...
  2. ncbi Protein kinase G is required for intrinsic antibiotic resistance in mycobacteria
    Kerstin A Wolff
    Department of Molecular Biology and Microbiology, Case Western Reserve University, School of Medicine, Wood Building, 10900 Euclid Avenue, Cleveland, OH 44106 4960, USA
    Antimicrob Agents Chemother 53:3515-9. 2009
    ..Here we show that PknG, a eukaryotic-type protein kinase previously found to support survival of mycobacteria in host cells, is required for the intrinsic resistance of mycobacterial species to multiple antibiotics...
  3. ncbi A lipoprotein modulates activity of the MtrAB two-component system to provide intrinsic multidrug resistance, cytokinetic control and cell wall homeostasis in Mycobacterium
    Hoa T Nguyen
    Department of Molecular Biology and Microbiology, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Mol Microbiol 76:348-64. 2010
    ..These results support a model in which LpqB, MtrB and MtrA form a three-component system that co-ordinates cytokinetic and cell wall homeostatic processes...