Rajeev K Mehlotra

Summary

Affiliation: Case Western Reserve University
Country: USA

Publications

  1. pmc Malaria infections are randomly distributed in diverse holoendemic areas of Papua New Guinea
    Rajeev K Mehlotra
    Center for Global Health and Diseases, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106 4983, USA
    Am J Trop Med Hyg 67:555-62. 2002
  2. pmc Chemokine (C-C motif) receptor 5 -2459 genotype in patients receiving highly active antiretroviral therapy: race-specific influence on virologic success
    Rajeev K Mehlotra
    Center for Global Health and Diseases and Diseases, Wolstein Research Bldg, Room 4204, 2103 Cornell Rd, Cleveland, OH 44106 7286, USA
    J Infect Dis 204:291-8. 2011
  3. ncbi request reprint Insight into the early spread of chloroquine-resistant Plasmodium falciparum infections in Papua New Guinea
    Rajeev K Mehlotra
    Center for Global Health and Diseases, Case Western Reserve University, School of Medicine, Cleveland, OH 44106, USA
    J Infect Dis 192:2174-9. 2005
  4. ncbi request reprint Prevalence of CYP2B6 alleles in malaria-endemic populations of West Africa and Papua New Guinea
    Rajeev K Mehlotra
    Center for Global Health and Diseases, School of Medicine, Case Western Reserve University, Wolstein Research Building 4204, Cleveland, OH 44106 7286, USA
    Eur J Clin Pharmacol 62:267-75. 2006
  5. pmc Prevalence of UGT1A9 and UGT2B7 nonsynonymous single nucleotide polymorphisms in West African, Papua New Guinean, and North American populations
    Rajeev K Mehlotra
    Center for Global Health and Diseases, Case Western Reserve University, School of Medicine, Wolstein Research Building 4204, 2103 Cornell Road, Cleveland, OH 44106 7286, USA
    Eur J Clin Pharmacol 63:1-8. 2007
  6. pmc Application of pharmacogenomics to malaria: a holistic approach for successful chemotherapy
    Rajeev K Mehlotra
    Center for Global Health and Diseases, Case Western Reserve University, School of Medicine, Wolstein Research Building 4204, 2103 Cornell Road, Cleveland, OH 44106 7286, USA
    Pharmacogenomics 10:435-49. 2009
  7. pmc Discordant patterns of genetic variation at two chloroquine resistance loci in worldwide populations of the malaria parasite Plasmodium falciparum
    Rajeev K Mehlotra
    Center for Global Health and Diseases, Case Western Reserve University, School of Medicine, Wolstein Research Building, room no 4204, 2103 Cornell Road, Cleveland, OH 44106 7286, USA
    Antimicrob Agents Chemother 52:2212-22. 2008
  8. doi request reprint Comparative description of haplotype structure and genetic diversity of MDR1 (ABCB1) in HIV-positive and HIV-negative populations
    Rebekah L Benish
    Center for Global Health and Diseases, School of Medicine, Case Western Reserve University, Cleveland, OH, USA
    Infect Genet Evol 10:60-7. 2010
  9. pmc CYP2B6 983T>C polymorphism is prevalent in West Africa but absent in Papua New Guinea: implications for HIV/AIDS treatment
    Rajeev K Mehlotra
    Center for Global Health and Diseases, Case Western Reserve University, School of Medicine, Cleveland, OH, USA
    Br J Clin Pharmacol 64:391-5. 2007
  10. pmc Microsatellite polymorphism within pfcrt provides evidence of continuing evolution of chloroquine-resistant alleles in Papua New Guinea
    Jeana T DaRe
    Case Western Reserve University, Wolstein Research Building, Cleveland, OH 44106, USA
    Malar J 6:34. 2007

Detail Information

Publications12

  1. pmc Malaria infections are randomly distributed in diverse holoendemic areas of Papua New Guinea
    Rajeev K Mehlotra
    Center for Global Health and Diseases, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106 4983, USA
    Am J Trop Med Hyg 67:555-62. 2002
    ....
  2. pmc Chemokine (C-C motif) receptor 5 -2459 genotype in patients receiving highly active antiretroviral therapy: race-specific influence on virologic success
    Rajeev K Mehlotra
    Center for Global Health and Diseases and Diseases, Wolstein Research Bldg, Room 4204, 2103 Cornell Rd, Cleveland, OH 44106 7286, USA
    J Infect Dis 204:291-8. 2011
    ..In patients receiving highly active antiretroviral therapy (HAART), antiretroviral drug-metabolizing enzyme and transporter gene polymorphisms, as well as chemokine receptor gene polymorphisms, may influence response to treatment...
  3. ncbi request reprint Insight into the early spread of chloroquine-resistant Plasmodium falciparum infections in Papua New Guinea
    Rajeev K Mehlotra
    Center for Global Health and Diseases, Case Western Reserve University, School of Medicine, Cleveland, OH 44106, USA
    J Infect Dis 192:2174-9. 2005
    ..These results suggest that selection for CQR was operating on the pfcrt-SVMNT allele during the early 1980s. Thus, archival samples can provide novel insight into the dynamics of CQR...
  4. ncbi request reprint Prevalence of CYP2B6 alleles in malaria-endemic populations of West Africa and Papua New Guinea
    Rajeev K Mehlotra
    Center for Global Health and Diseases, School of Medicine, Case Western Reserve University, Wolstein Research Building 4204, Cleveland, OH 44106 7286, USA
    Eur J Clin Pharmacol 62:267-75. 2006
    ..Our aim was to analyze the prevalence of the most commonly observed CYP2B6 alleles in malaria-endemic populations of West Africa (WA) and Papua New Guinea (PNG)...
  5. pmc Prevalence of UGT1A9 and UGT2B7 nonsynonymous single nucleotide polymorphisms in West African, Papua New Guinean, and North American populations
    Rajeev K Mehlotra
    Center for Global Health and Diseases, Case Western Reserve University, School of Medicine, Wolstein Research Building 4204, 2103 Cornell Road, Cleveland, OH 44106 7286, USA
    Eur J Clin Pharmacol 63:1-8. 2007
    ..Our aim was to analyze the prevalence of UGT1A9 (chromosome 2) and UGT2B7 (chromosome 4) nonsynonymous single nucleotide polymorphisms (SNPs) in West African (WA), Papua New Guinean (PNG), and North American (NA) populations...
  6. pmc Application of pharmacogenomics to malaria: a holistic approach for successful chemotherapy
    Rajeev K Mehlotra
    Center for Global Health and Diseases, Case Western Reserve University, School of Medicine, Wolstein Research Building 4204, 2103 Cornell Road, Cleveland, OH 44106 7286, USA
    Pharmacogenomics 10:435-49. 2009
    ....
  7. pmc Discordant patterns of genetic variation at two chloroquine resistance loci in worldwide populations of the malaria parasite Plasmodium falciparum
    Rajeev K Mehlotra
    Center for Global Health and Diseases, Case Western Reserve University, School of Medicine, Wolstein Research Building, room no 4204, 2103 Cornell Road, Cleveland, OH 44106 7286, USA
    Antimicrob Agents Chemother 52:2212-22. 2008
    ....
  8. doi request reprint Comparative description of haplotype structure and genetic diversity of MDR1 (ABCB1) in HIV-positive and HIV-negative populations
    Rebekah L Benish
    Center for Global Health and Diseases, School of Medicine, Case Western Reserve University, Cleveland, OH, USA
    Infect Genet Evol 10:60-7. 2010
    ....
  9. pmc CYP2B6 983T>C polymorphism is prevalent in West Africa but absent in Papua New Guinea: implications for HIV/AIDS treatment
    Rajeev K Mehlotra
    Center for Global Health and Diseases, Case Western Reserve University, School of Medicine, Cleveland, OH, USA
    Br J Clin Pharmacol 64:391-5. 2007
    ..To determine the prevalence of the novel CYP2B6 functional polymorphism 983T>C in Papua New Guinea where HIV/AIDS poses a significant health problem...
  10. pmc Microsatellite polymorphism within pfcrt provides evidence of continuing evolution of chloroquine-resistant alleles in Papua New Guinea
    Jeana T DaRe
    Case Western Reserve University, Wolstein Research Building, Cleveland, OH 44106, USA
    Malar J 6:34. 2007
    ..Previous studies have shown that microsatellite (MS) haplotype variation can be used to study the evolution of CQR polymorphism and to characterize intra- and inter-population dispersal of CQR in Papua New Guinea (PNG)...
  11. pmc Why do we need to know more about mixed Plasmodium species infections in humans?
    Peter A Zimmerman
    The Center for Global Health and Diseases, Case Western Reserve University, 2103 Cornell Road, Wolstein Research Building, Cleveland, OH 44106 7286, USA
    Trends Parasitol 20:440-7. 2004
    ..This should ensure that deployment of future antimalarial vaccines and drugs will be conducted in a safe and timely manner...
  12. pmc Molecular-based assay for simultaneous detection of four Plasmodium spp. and Wuchereria bancrofti infections
    Rajeev K Mehlotra
    Center for Global Health and Diseases, Case Western Reserve University School of Medicine, Cleveland, OH, USA
    Am J Trop Med Hyg 82:1030-3. 2010
    ..bancrofti (90%) diagnoses. The development of this assay for the simultaneous diagnosis of multiple parasitic infections enables efficient screening of large numbers of human blood and mosquito samples from co-endemic areas...