Danny Manor

Summary

Affiliation: Case Western Reserve University
Country: USA

Publications

  1. ncbi Regulation of proto-oncogenic dbl by chaperone-controlled, ubiquitin-mediated degradation
    Elena Kamynina
    Case School of Medicine, WG 48, Case Western Reserve University, Cleveland, OH 44106, USA
    Mol Cell Biol 27:1809-22. 2007
  2. ncbi Regulation of the Dbl proto-oncogene by heat shock cognate protein 70 (Hsc70)
    Krista P Kauppinen
    Division of Nutritional Sciences, Cornell University, Ithaca, New York 14853, USA
    J Biol Chem 280:21638-44. 2005

Research Grants

  1. Cell Transformation by Dbl-like onco-proteins
    Danny Manor; Fiscal Year: 2006
  2. Functions of Tocopherol Transfer Protein
    Danny Manor; Fiscal Year: 2007

Collaborators

  • Elena Kamynina
  • Faping Duan
  • Krista P Kauppinen
  • Krista Kauppinen
  • Nora Muakkassa
  • Jared I Wels

Detail Information

Publications2

  1. ncbi Regulation of proto-oncogenic dbl by chaperone-controlled, ubiquitin-mediated degradation
    Elena Kamynina
    Case School of Medicine, WG 48, Case Western Reserve University, Cleveland, OH 44106, USA
    Mol Cell Biol 27:1809-22. 2007
    ..Onco-Dbl, lacking the spectrin homology domain, cannot bind these regulators and therefore accumulates in cells at high levels, leading to persistent stimulation of its downstream signaling pathways...
  2. ncbi Regulation of the Dbl proto-oncogene by heat shock cognate protein 70 (Hsc70)
    Krista P Kauppinen
    Division of Nutritional Sciences, Cornell University, Ithaca, New York 14853, USA
    J Biol Chem 280:21638-44. 2005
    ..We propose that Hsc70 attenuates Dbl activity by maintaining an inactive conformation in which the amino terminus is "folded over" the catalytic DH-PH domain...

Research Grants4

  1. Cell Transformation by Dbl-like onco-proteins
    Danny Manor; Fiscal Year: 2006
    ..abstract_text> ..
  2. Functions of Tocopherol Transfer Protein
    Danny Manor; Fiscal Year: 2007
    ..Studies proposed in this application will provide critical information that is likely to improve our understanding of vitamin E function as a mediator of human health. ..