Research Topics
Species | Alan J LernerSummaryAffiliation: Case Western Reserve University Country: USA Publications
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Detail Information
Publications
Retinoids for treatment of Alzheimer's diseaseAlan J Lerner
Department of Neurology, University Hospitals Case Medical Center, Cleveland, OH, USA
Biofactors 38:84-9. 2012..These studies need to address safety issues of retinoids in older populations, and hold hope for demonstrating efficacy in translating these basic mechanisms to treatment of a widespread dementing illness...
Network graph analysis of category fluency testingAlan J Lerner
Department of Neurology, University Hospitals Case Medical Center, Cleveland, OH 44120, USA
Cogn Behav Neurol 22:45-52. 2009..Scale-free networks are characterized by the presence of a few nodes with many connections, and many more nodes with fewer connections...
Factors affecting usage patterns of memantine in Alzheimer diseaseAlan J Lerner
Department of Neurology, University Hospitals Case Medical Center, Cleveland, OH, USA
Alzheimer Dis Assoc Disord 22:137-43. 2008..Use of memantine in mild AD was common. Patterns of memantine usage are complex and deserve further study in a larger sample because of their implications for medical system cost, equitable access to care, and risk of drug interactions...
Pharmacological treatment of Alzheimer's disease: effect of race and demographic variablesSantiago Hernandez
Case Western Reserve University, School of Medicine, Cleveland, OH, USA
J Alzheimers Dis 19:665-72. 2010..Research and initiatives at the societal level may be an important consideration toward addressing these differences...
Height and Alzheimer's disease: findings from a case-control studyGrace J Petot
Department of Nutrition, School of Medicine, Case Western Reserve University, Cleveland, OH, USA
J Alzheimers Dis 11:337-41. 2007..03). For women without an APOE epsilon4 allele, increasing height was associated with lower risk for AD (OR=0.88; p=0.01) but no significant association was found for women with at least one epsilon4 allele (OR=1.03; p=0.56)...
Memantine and acetylcholinesterase inhibitor treatment in cases of CDR 0.5 or questionable impairmentMcKee J McClendon
University Memory and Aging Center, Cleveland, OH, USA
J Alzheimers Dis 16:577-83. 2009..5 is frequent and represents evidence for extensive off label usage. Diagnosis, severity of impairment, and race, among other variables, affect the likelihood of AChEI and memantine use in this population...
Interactions of apolipoprotein E genotype and dietary fat intake of healthy older persons during mid-adult lifeGrace J Petot
Department of Nutrition, The University Memory and Aging Center, Cleveland, OH 44120 1013, USA
Metabolism 52:279-81. 2003..Diet-genotype interactions may have important influences on disorders of later life...
Recognizing apathy in Alzheimer's diseaseAlan J Lerner
Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
Geriatrics 62:14-7. 2007..It must also be recognized that apathy per se almost never occurs as an isolated syndrome, so it must be viewed in the context of an individual's entire behavioral and cognitive status...
Random local temporal structure of category fluency responsesDavid J Meyer
Case Western Reserve University, 11900 Euclid Avenue, Cleveland, OH 44106, USA
J Comput Neurosci 32:213-31. 2012..This insight leads us to a new interpretation of the concept of "navigating a semantic space" via patient responses...
Probing the mechanism of saccade-associated head movements through observations of head movement propensity and cognition in the elderlyZachary C Thumser
Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH, USA
Exp Brain Res 202:903-13. 2010....
Use of surrogate respondents in a case control study of dietary risk factors for Alzheimer's diseaseGrace J Petot
Department of Nutrition, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44120, USA
J Am Diet Assoc 102:848-50. 2002
Ketamine for refractory status epilepticus: a case of possible ketamine-induced neurotoxicityEroboghene E Ubogu
Department of Neurology, University Hospitals of Cleveland, Hanna House 5th Floor, 11100 Euclid Avenue, Cleveland, OH 44106-5040, USA
Epilepsy Behav 4:70-5. 2003..Animal studies of prolonged ketamine therapy are required before widespread human use in SE...
The relationships between television viewing in midlife and the development of Alzheimer's disease in a case-control studyHeather A Lindstrom
University Memory and Aging Center, Case Western Reserve University, USA
Brain Cogn 58:157-65. 2005....
