MICHAEL LAMM

Summary

Affiliation: Case Western Reserve University
Country: USA

Publications

  1. ncbi request reprint Interaction of antigens and antibodies at mucosal surfaces
    M E Lamm
    Institute of Pathology, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Annu Rev Microbiol 51:311-40. 1997
  2. pmc Origin and homing of intestinal IgA antibody-secreting cells
    Michael E Lamm
    Department of Pathology, Case Western Reserve University, Cleveland, OH 44106, USA
    J Exp Med 195:F5-8. 2002
  3. pmc Multiple functions of immunoglobulin A in mucosal defense against viruses: an in vitro measles virus model
    Huimin Yan
    Institute of Pathology, Case Western Reserve University, University Hospitals of Cleveland, Cleveland, Ohio 44106, USA
    J Virol 76:10972-9. 2002
  4. ncbi request reprint Differential effects of Sendai virus infection on mediator synthesis by mesangial cells from two mouse strains
    Noriyoshi Kobayashi
    Institute of Pathology, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Kidney Int 64:1675-84. 2003
  5. ncbi request reprint Intraepithelial cell neutralization of HIV-1 replication by IgA
    Yung T Huang
    Institute of Pathology, Case Western Reserve University, Cleveland, OH 44106, USA
    J Immunol 174:4828-35. 2005
  6. pmc Immunoglobulin A antibodies against internal HIV-1 proteins neutralize HIV-1 replication inside epithelial cells
    Alison Wright
    Institute of Pathology, Case Western Reserve University, Cleveland, OH 44106, USA
    Virology 356:165-70. 2006
  7. ncbi request reprint Analysis of innate immune responses in a model of IgA nephropathy induced by Sendai virus
    Michifumi Yamashita
    Department of Pathology, Case Western Reserve University, Cleveland, Ohio 44106 7288, USA
    Contrib Nephrol 157:159-63. 2007
  8. pmc Microbial IgA protease removes IgA immune complexes from mouse glomeruli in vivo: potential therapy for IgA nephropathy
    Michael E Lamm
    Department of Pathology, Case Western Reserve University, 10900 Euclid Avenue, Wolstein Research Building, Room 5531, Cleveland, OH 44106, USA
    Am J Pathol 172:31-6. 2008

Research Grants

  1. SECRETORY IMMUNOGLOBULIN
    MICHAEL LAMM; Fiscal Year: 2002
  2. SECRETORY IMMUNOGLOBULIN
    MICHAEL LAMM; Fiscal Year: 1992
  3. SECRETORY IMMUNOGLOBULIN
    MICHAEL LAMM; Fiscal Year: 1993

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Interaction of antigens and antibodies at mucosal surfaces
    M E Lamm
    Institute of Pathology, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Annu Rev Microbiol 51:311-40. 1997
    ..Finally, because of advances in monoclonal antibody technology, topical application of antibodies to mucosal surfaces has significant potential for preventing and treating infections...
  2. pmc Origin and homing of intestinal IgA antibody-secreting cells
    Michael E Lamm
    Department of Pathology, Case Western Reserve University, Cleveland, OH 44106, USA
    J Exp Med 195:F5-8. 2002
  3. pmc Multiple functions of immunoglobulin A in mucosal defense against viruses: an in vitro measles virus model
    Huimin Yan
    Institute of Pathology, Case Western Reserve University, University Hospitals of Cleveland, Cleveland, Ohio 44106, USA
    J Virol 76:10972-9. 2002
    ....
  4. ncbi request reprint Differential effects of Sendai virus infection on mediator synthesis by mesangial cells from two mouse strains
    Noriyoshi Kobayashi
    Institute of Pathology, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Kidney Int 64:1675-84. 2003
    ....
  5. ncbi request reprint Intraepithelial cell neutralization of HIV-1 replication by IgA
    Yung T Huang
    Institute of Pathology, Case Western Reserve University, Cleveland, OH 44106, USA
    J Immunol 174:4828-35. 2005
    ..Control studies with two kinds of conditioned medium confirmed that HIV neutralization had indeed occurred inside the cells. Thus, during its transcytosis through epithelial cells, HIV-specific IgA can neutralize HIV replication...
  6. pmc Immunoglobulin A antibodies against internal HIV-1 proteins neutralize HIV-1 replication inside epithelial cells
    Alison Wright
    Institute of Pathology, Case Western Reserve University, Cleveland, OH 44106, USA
    Virology 356:165-70. 2006
    ..Thus, at least in the context of infections of polarized epithelia, antibody-mediated neutralization may not be restricted to viral surface antigens...
  7. ncbi request reprint Analysis of innate immune responses in a model of IgA nephropathy induced by Sendai virus
    Michifumi Yamashita
    Department of Pathology, Case Western Reserve University, Cleveland, Ohio 44106 7288, USA
    Contrib Nephrol 157:159-63. 2007
    ..Natural IFN-gamma production may influence the risk of renal failure in IgAN...
  8. pmc Microbial IgA protease removes IgA immune complexes from mouse glomeruli in vivo: potential therapy for IgA nephropathy
    Michael E Lamm
    Department of Pathology, Case Western Reserve University, 10900 Euclid Avenue, Wolstein Research Building, Room 5531, Cleveland, OH 44106, USA
    Am J Pathol 172:31-6. 2008
    ..Thus, IgA protease may have potential as a therapeutic agent for human IgAN...

Research Grants17

  1. SECRETORY IMMUNOGLOBULIN
    MICHAEL LAMM; Fiscal Year: 2002
    ....
  2. SECRETORY IMMUNOGLOBULIN
    MICHAEL LAMM; Fiscal Year: 1992
  3. SECRETORY IMMUNOGLOBULIN
    MICHAEL LAMM; Fiscal Year: 1993
    ..The insights afforded should aid in developing practical strategies for mucosal immunization...