E S Kaufman

Summary

Affiliation: Case Western Reserve University
Country: USA

Publications

  1. ncbi request reprint Electrocardiographic prediction of abnormal genotype in congenital long QT syndrome: experience in 101 related family members
    E S Kaufman
    The Heart and Vascular Research Center, Case Western Reserve University, Cleveland, Ohio 44109 1998, USA
    J Cardiovasc Electrophysiol 12:455-61. 2001
  2. pmc Microvolt-level T-wave alternans determination using the spectral method in patients with QT prolongation: value of adjusting the T-wave window
    Elizabeth S Kaufman
    Heart and Vascular Research Center, MetroHealth Campus of Case Western Reserve University, Cleveland, OH 44109 1998, USA
    J Electrocardiol 45:758-63. 2012
  3. doi request reprint Positive predictive value of device-detected atrial high-rate episodes at different rates and durations: an analysis from ASSERT
    Elizabeth S Kaufman
    Heart and Vascular Research Center, MetroHealth Campus of Case Western Reserve University, Cleveland, Ohio 44109, USA
    Heart Rhythm 9:1241-6. 2012
  4. doi request reprint Arrhythmic risk in congenital long QT syndrome
    Elizabeth S Kaufman
    Heart and Vascular Research Center, MetroHealth Campus of Case Western Reserve University, Cleveland, OH 44109 1998, USA
    J Electrocardiol 44:645-9. 2011
  5. doi request reprint Mechanisms and clinical management of inherited channelopathies: long QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia, and short QT syndrome
    Elizabeth S Kaufman
    Heart and Vascular Research Center, MetroHealth Campus of Case Western Reserve University, Cleveland, Ohio 44109 1998, USA
    Heart Rhythm 6:S51-5. 2009
  6. pmc Risk of death in the long QT syndrome when a sibling has died
    Elizabeth S Kaufman
    Heart and Vascular Research Center, MetroHealth Campus, Case Western Reserve University, Cleveland, Ohio, USA
    Heart Rhythm 5:831-6. 2008
  7. ncbi request reprint "Indeterminate" microvolt T-wave alternans tests predict high risk of death or sustained ventricular arrhythmias in patients with left ventricular dysfunction
    Elizabeth S Kaufman
    Heart and Vascular Research Center, MetroHealth Campus of Case Western Reserve University, Cleveland, Ohio 44109 1998, USA
    J Am Coll Cardiol 48:1399-404. 2006
  8. ncbi request reprint Use of autonomic maneuvers to probe phenotype/genotype discordance in congenital long QT syndrome
    Elizabeth S Kaufman
    Heart and Vascular Research Center, MetroHealth Campus of Case Western Reserve University, Cleveland, Ohio, USA
    Am J Cardiol 96:1425-30. 2005
  9. ncbi request reprint Risk of proarrhythmic events in the Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) study: a multivariate analysis
    Elizabeth S Kaufman
    Heart and Vascular Research Center, Hamann 3rd Floor, MetroHealth Campus, Case Western Reserve University, 2500 MetroHealth Drive, Cleveland, Ohio 44109 1998, USA
    J Am Coll Cardiol 44:1276-82. 2004
  10. ncbi request reprint Is restoration of intracellular trafficking clinically feasible in the long QT syndrome?: The example of HERG mutations
    Elizabeth S Kaufman
    The Heart and Vascular Research Center and Rammelkamp Center for Education and Research, MetroHealth Campus, Case Western Reserve University, Cleveland, Ohio 44109 1998, USA
    J Cardiovasc Electrophysiol 14:320-2. 2003

Collaborators

Detail Information

Publications39

  1. ncbi request reprint Electrocardiographic prediction of abnormal genotype in congenital long QT syndrome: experience in 101 related family members
    E S Kaufman
    The Heart and Vascular Research Center, Case Western Reserve University, Cleveland, Ohio 44109 1998, USA
    J Cardiovasc Electrophysiol 12:455-61. 2001
    ..We hypothesized that a combination of clinical and ECG techniques could identify gene carriers within a single family with congenital LQTS...
  2. pmc Microvolt-level T-wave alternans determination using the spectral method in patients with QT prolongation: value of adjusting the T-wave window
    Elizabeth S Kaufman
    Heart and Vascular Research Center, MetroHealth Campus of Case Western Reserve University, Cleveland, OH 44109 1998, USA
    J Electrocardiol 45:758-63. 2012
    ..MTWA analysis software selects a segment of the ECG that encompasses the T-wave in most individuals, but may miss the T-wave end in patients with QT prolongation...
  3. doi request reprint Positive predictive value of device-detected atrial high-rate episodes at different rates and durations: an analysis from ASSERT
    Elizabeth S Kaufman
    Heart and Vascular Research Center, MetroHealth Campus of Case Western Reserve University, Cleveland, Ohio 44109, USA
    Heart Rhythm 9:1241-6. 2012
    ..As AHREs may lead to the initiation of oral anticoagulation, it is crucial to understand the relationship between AHREs and true AT/AF...
  4. doi request reprint Arrhythmic risk in congenital long QT syndrome
    Elizabeth S Kaufman
    Heart and Vascular Research Center, MetroHealth Campus of Case Western Reserve University, Cleveland, OH 44109 1998, USA
    J Electrocardiol 44:645-9. 2011
    ....
  5. doi request reprint Mechanisms and clinical management of inherited channelopathies: long QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia, and short QT syndrome
    Elizabeth S Kaufman
    Heart and Vascular Research Center, MetroHealth Campus of Case Western Reserve University, Cleveland, Ohio 44109 1998, USA
    Heart Rhythm 6:S51-5. 2009
    ..ICD implantation is the primary therapy; quinidine may be a useful adjunctive therapy...
  6. pmc Risk of death in the long QT syndrome when a sibling has died
    Elizabeth S Kaufman
    Heart and Vascular Research Center, MetroHealth Campus, Case Western Reserve University, Cleveland, Ohio, USA
    Heart Rhythm 5:831-6. 2008
    ..Sudden death of a sibling is thought to be associated with greater risk of death in long QT syndrome (LQTS). However, there is no evidence of such an association...
  7. ncbi request reprint "Indeterminate" microvolt T-wave alternans tests predict high risk of death or sustained ventricular arrhythmias in patients with left ventricular dysfunction
    Elizabeth S Kaufman
    Heart and Vascular Research Center, MetroHealth Campus of Case Western Reserve University, Cleveland, Ohio 44109 1998, USA
    J Am Coll Cardiol 48:1399-404. 2006
    ..This study tested the hypothesis that an "indeterminate" microvolt T-wave alternans (MTWA) test, when due to ectopy, unsustained MTWA, or low exercise heart rate (HR), has prognostic significance similar to a positive MTWA test...
  8. ncbi request reprint Use of autonomic maneuvers to probe phenotype/genotype discordance in congenital long QT syndrome
    Elizabeth S Kaufman
    Heart and Vascular Research Center, MetroHealth Campus of Case Western Reserve University, Cleveland, Ohio, USA
    Am J Cardiol 96:1425-30. 2005
    ..01, at 1 minute into recovery) but not in subjects with LQT2. In conclusion, sympathetic stimulation can reveal the LQT1 phenotype even in subjects with normal baseline electrocardiographic findings...
  9. ncbi request reprint Risk of proarrhythmic events in the Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) study: a multivariate analysis
    Elizabeth S Kaufman
    Heart and Vascular Research Center, Hamann 3rd Floor, MetroHealth Campus, Case Western Reserve University, 2500 MetroHealth Drive, Cleveland, Ohio 44109 1998, USA
    J Am Coll Cardiol 44:1276-82. 2004
    ..This study examined the risk of proarrhythmic events in patients receiving antiarrhythmic drugs for treatment of atrial fibrillation (AF) according to present-day safety guidelines...
  10. ncbi request reprint Is restoration of intracellular trafficking clinically feasible in the long QT syndrome?: The example of HERG mutations
    Elizabeth S Kaufman
    The Heart and Vascular Research Center and Rammelkamp Center for Education and Research, MetroHealth Campus, Case Western Reserve University, Cleveland, Ohio 44109 1998, USA
    J Cardiovasc Electrophysiol 14:320-2. 2003
  11. ncbi request reprint Heart rate variability in cocaine-exposed newborn infants
    S K Mehta
    Fairview Hospital and MetroHealth Medical Center, Department of Pediatrics and Heart and Vascular Center, MetroHealth Campus, Case Western Reserve University, Cleveland, Ohio 44111 5656, USA
    Am Heart J 142:828-32. 2001
    ..Its underlying cause, in part, may be attributed to abnormal autonomic function. We proposed to study heart rate variability, reflecting autonomic control of the heart, in cocaine-exposed infants...
  12. ncbi request reprint Risk of aborted cardiac arrest or sudden cardiac death during adolescence in the long-QT syndrome
    Jenny B Hobbs
    Cardiology Unit of the Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA
    JAMA 296:1249-54. 2006
    ..Risk factors specific for aborted cardiac arrest and sudden cardiac death have not been investigated...
  13. ncbi request reprint Microvolt T-wave alternans and the risk of death or sustained ventricular arrhythmias in patients with left ventricular dysfunction
    Daniel M Bloomfield
    Columbia University Medical Center, New York, New York 10032, USA
    J Am Coll Cardiol 47:456-63. 2006
    ..This study hypothesized that microvolt T-wave alternans (MTWA) improves selection of patients for implantable cardioverter-defibrillator (ICD) prophylaxis, especially by identifying patients who are not likely to benefit...
  14. doi request reprint Long-QT syndrome after age 40
    Ilan Goldenberg
    Cardiology Division of the Department of Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA
    Circulation 117:2192-201. 2008
    ....
  15. ncbi request reprint I(Kr) channel blockade to unmask occult congenital long QT syndrome
    Darwin Jeyaraj
    Heart and Vascular Research Center, MetroHealth Campus of Case Western Reserve University, Cleveland, Ohio 44109 1998, USA
    Heart Rhythm 5:2-7. 2008
    ..Beta-adrenergic stimulation may unmask occult LQT1, but no maneuver has consistently unmasked the LQT2 phenotype...
  16. ncbi request reprint Quinidine in short QT syndrome: an old drug for a new disease
    Elizabeth S Kaufman
    J Cardiovasc Electrophysiol 18:665-6. 2007
  17. ncbi request reprint Repolarization dynamics in patients with long QT syndrome
    Juha S Perkiomaki
    Department of Medicine, University of Rochester School of Medicine and Dentistry, New York, USA
    J Cardiovasc Electrophysiol 13:651-6. 2002
    ..The aim of the present study was to assess the dynamics of repolarization duration and the dynamics of repolarization complexity in LQTS patients and their unaffected family members...
  18. ncbi request reprint Long QT syndrome in adults
    Andrew J Sauer
    Cardiology Unit of the Department of Medicine, University of Rochester Medical Center, Rochester, New York 14642 8653, USA
    J Am Coll Cardiol 49:329-37. 2007
    ....
  19. ncbi request reprint Long QT syndrome and pregnancy
    Rahul Seth
    Cardiology Division of the Department of Medicine, University of Rochester Medical Center, Rochester, New York 14642, USA
    J Am Coll Cardiol 49:1092-8. 2007
    ..This study was designed to investigate the clinical course of women with long QT syndrome (LQTS) throughout their potential childbearing years...
  20. doi request reprint Risk factors for aborted cardiac arrest and sudden cardiac death in children with the congenital long-QT syndrome
    Ilan Goldenberg
    Cardiology Division of the Department of Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA
    Circulation 117:2184-91. 2008
    ..However, specific risk factors for life-threatening cardiac events in children with this genetic disorder have not been identified...
  21. ncbi request reprint Increased risk of arrhythmic events in long-QT syndrome with mutations in the pore region of the human ether-a-go-go-related gene potassium channel
    Arthur J Moss
    Cardiology Unit of the Department of Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA
    Circulation 105:794-9. 2002
    ..We investigated the clinical features and prognostic implications of mutations involving pore and nonpore regions of the HERG channel in the LQT2 form of this disorder...
  22. ncbi request reprint Variable expression of long QT syndrome among gene carriers from families with five different HERG mutations
    Jesaia Benhorin
    Department of Cardiology, Bikur Cholim Hospital, Jerusalem, Israel
    Ann Noninvasive Electrocardiol 7:40-6. 2002
    ..This study assessed the phenotypic variability of LQTS in carriers with the same and with different mutations in the LQT2 gene...
  23. ncbi request reprint AHA scientific statement: practice standards for electrocardiographic monitoring in hospital settings: an American Heart Association Scientific Statement from the Councils on Cardiovascular Nursing, Clinical Cardiology, and Cardiovascular Disease in the Y
    Barbara J Drew
    J Cardiovasc Nurs 20:76-106. 2005
    ..Currently available ECG lead systems are described, and recommendations related to staffing, training, and methods to improve quality are provided...
  24. ncbi request reprint Practice standards for electrocardiographic monitoring in hospital settings: an American Heart Association scientific statement from the Councils on Cardiovascular Nursing, Clinical Cardiology, and Cardiovascular Disease in the Young: endorsed by the Inte
    Barbara J Drew
    Circulation 110:2721-46. 2004
    ..Currently available ECG lead systems are described, and recommendations related to staffing, training, and methods to improve quality are provided...
  25. ncbi request reprint Microvolt T-wave alternans distinguishes between patients likely and patients not likely to benefit from implanted cardiac defibrillator therapy: a solution to the Multicenter Automatic Defibrillator Implantation Trial (MADIT) II conundrum
    Daniel M Bloomfield
    Data Coordinating Center, The MTWA in CHF Study, PH 9 103D, Department of Medicine, Columbia University, 630 W 168th St, New York, NY 10032, USA
    Circulation 110:1885-9. 2004
    ..We compared the ability of microvolt T-wave alternans and QRS duration to identify groups at high and low risk of dying among heart failure patients who met MADIT II criteria for ICD prophylaxis...
  26. ncbi request reprint Location of mutation in the KCNQ1 and phenotypic presentation of long QT syndrome
    Wojciech Zareba
    Cardiology Unit of the Department of Medicine, Heart Research Follow Up Program, Box 653, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Cardiovasc Electrophysiol 14:1149-53. 2003
    ..The aim of this study was to determine whether there is an association between the location of mutations in the KCNQ1 gene and cardiac events in LQT1 patients...
  27. pmc Clinical aspects of type-1 long-QT syndrome by location, coding type, and biophysical function of mutations involving the KCNQ1 gene
    Arthur J Moss
    Cardiology Division, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
    Circulation 115:2481-9. 2007
    ..We evaluated the effect of location, coding type, and biophysical function of KCNQ1 mutations on the clinical phenotype of this disorder...
  28. doi request reprint A surprise wireless remote transmission
    Elizabeth S Kaufman
    Heart Rhythm 5:1092. 2008
  29. ncbi request reprint Heart rate variability in healthy newborn infants
    Sudhir Ken Mehta
    Fairview Hospital and MetroHealth Medical Center, Cleveland, Ohio 44111 5656, USA
    Am J Cardiol 89:50-3. 2002
    ..Because the data are reported as means +/- SD, medians, and 5th and 95th percentiles, their use facilitates the study of parasympathetic and sympathetic activity in comparable populations...
  30. ncbi request reprint Saving lives in congenital long QT syndrome: who benefits from implantable cardioverter defibrillator therapy?
    Elizabeth S Kaufman
    J Cardiovasc Electrophysiol 14:342-3. 2003
  31. ncbi request reprint The impact of asymptomatic atrial fibrillation
    Elizabeth S Kaufman
    J Am Coll Cardiol 43:53-4. 2004
  32. ncbi request reprint How to find the high-risk patient among individuals with a Brugada syndrome-type electrocardiogram
    Elizabeth S Kaufman
    J Cardiovasc Electrophysiol 16:52-3. 2005
  33. ncbi request reprint Occurrence and characteristics of stroke events in the Atrial Fibrillation Follow-up Investigation of Sinus Rhythm Management (AFFIRM) study
    David G Sherman
    University of Texas Health Science Center, San Antonio, USA
    Arch Intern Med 165:1185-91. 2005
    ..The Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) Study was a multicenter comparison of high-risk patients with AF who were randomized to either a sinus rhythm control or a rate control strategy...
  34. ncbi request reprint Can common genetic variations combine to produce the long QT syndrome phenotype?
    Elizabeth S Kaufman
    Heart Rhythm 2:748-9. 2005
  35. ncbi request reprint Autonomic alterations in cocaine-exposed infants
    Sudhir Ken Mehta
    Fairview Hospital and MetroHealth Medical Center, Cleveland, Ohio 44111 5656, USA
    Am Heart J 144:1109-15. 2002
    ..It is unknown whether these alterations are transient (acute effect) or persist in older infants and possibly reflect a teratogenic effect of cocaine...
  36. ncbi request reprint Heart rate variability by triangular index in infants exposed prenatally to cocaine
    Sudhir Ken Mehta
    Department of Pediatrics, MetroHealth Campus, Case Western Reserve University, Fairview Hospital, 18101 Lorain Avenue, Cleveland, Ohio 44111 5656, USA
    Ann Noninvasive Electrocardiol 7:374-8. 2002
    ..Although normative data have been published for newborns, studies in infants with pathological conditions are lacking...
  37. ncbi request reprint Efficient genotyping for congenital long QT syndrome
    Elizabeth S Kaufman
    JAMA 294:3027-8. 2005
  38. ncbi request reprint Arrhythmogenic right ventricular cardiomyopathy: how should genetic information be integrated with clinical diagnostic criteria?
    Elizabeth S Kaufman
    Heart Rhythm 3:945-7. 2006
  39. ncbi request reprint Evaluation of suspected arrhythmic syncope: leaning away from tilting
    Elizabeth S Kaufman
    J Cardiovasc Electrophysiol 16:943-4. 2005