Hung Ying Kao


Affiliation: Case Western Reserve University
Country: USA


  1. Guo S, Cheng X, Lim J, Liu Y, Kao H. Control of antioxidative response by the tumor suppressor protein PML through regulating Nrf2 activity. Mol Biol Cell. 2014;25:2485-98 pubmed publisher
  2. Zhao X, Hsu K, Lim J, Bruggeman L, Kao H. α-Actinin 4 potentiates nuclear factor κ-light-chain-enhancer of activated B-cell (NF-κB) activity in podocytes independent of its cytoplasmic actin binding function. J Biol Chem. 2015;290:338-49 pubmed publisher
    ..Taken together, our data identify ACTN4 as a novel coactivator for NF-κB transcription factors in podocytes. Importantly, this nuclear function of ACTN4 is independent of its actin binding activity in the cytoplasm. ..
  3. Zhao X, Khurana S, Charkraborty S, Tian Y, Sedor J, Bruggman L, et al. ? Actinin 4 (ACTN4) Regulates Glucocorticoid Receptor-mediated Transactivation and Transrepression in Podocytes. J Biol Chem. 2017;292:1637-1647 pubmed publisher
  4. Hsu K, Zhao X, Cheng X, Guan D, Mahabeleshwar G, Liu Y, et al. Dual regulation of Stat1 and Stat3 by the tumor suppressor protein PML contributes to interferon ?-mediated inhibition of angiogenesis. J Biol Chem. 2017;292:10048-10060 pubmed publisher
    ..The interplay between PML, Stat1/Stat2, and Stat3 contributes to IFN?-mediated inhibition of angiogenesis, and disruption of this network results in aberrant IFN? signaling and altered angiostatic activity. ..