Robert C Kalayjian

Summary

Affiliation: Case Western Reserve University
Country: USA

Publications

  1. ncbi request reprint Kidney Disease in HIV-Infected Persons
    Robert C Kalayjian
    Division of Infectious Diseases, MetroHealth Medical Center, 2500 MetroHealth Dr, Cleveland, OH, 44109, USA
    Curr Infect Dis Rep 14:83-90. 2012
  2. pmc Older HIV-infected patients on antiretroviral therapy have B-cell expansion and attenuated CD4 cell increases with immune activation reduction
    Robert C Kalayjian
    MetroHealth Medical Center, Cleveland, OH, USA
    AIDS 27:1563-71. 2013
  3. ncbi request reprint Age-related immune dysfunction in health and in human immunodeficiency virus (HIV) disease: association of age and HIV infection with naive CD8+ cell depletion, reduced expression of CD28 on CD8+ cells, and reduced thymic volumes
    Robert C Kalayjian
    MetroHealth Medical Center and Case Western Reserve University, Cleveland, Ohio, USA
    J Infect Dis 187:1924-33. 2003
  4. doi request reprint Renal issues in HIV infection
    Robert C Kalayjian
    Division of Infectious Diseases, MetroHealth Medical Center, Cleveland, OH 44109, USA
    Curr HIV/AIDS Rep 8:164-71. 2011
  5. pmc Pretreatment levels of soluble cellular receptors and interleukin-6 are associated with HIV disease progression in subjects treated with highly active antiretroviral therapy
    Robert C Kalayjian
    MetroHealth Medical Center, Case Western Reserve University School of Medicine, Cleveland, Ohio 44109 1998, USA
    J Infect Dis 201:1796-805. 2010
  6. ncbi request reprint Distinct mechanisms of T cell reconstitution can be identified by estimating thymic volume in adult HIV-1 disease
    Robert C Kalayjian
    Division of Infectious Diseases, MetroHealth Medical Center and Case Western Reserve University, Cleveland, Ohio 44109 1998, USA
    J Infect Dis 192:1577-87. 2005
  7. pmc Suppression of HIV-1 replication by antiretroviral therapy improves renal function in persons with low CD4 cell counts and chronic kidney disease
    Robert C Kalayjian
    Department of Medicine, MetroHealth Medical Center, Cleveland, Ohio, USA
    AIDS 22:481-7. 2008
  8. pmc The effects of HIV type-1 viral suppression and non-viral factors on quantitative proteinuria in the highly active antiretroviral therapy era
    Samir K Gupta
    Division of Infectious Diseases, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
    Antivir Ther 14:543-9. 2009
  9. pmc The effect of aging on T-regulatory cell frequency in HIV infection
    Allan R Tenorio
    Section of Infectious Diseases, Department of Medicine, Rush Medical College, 600 S Paulina Street, Suite 143 AAC, Chicago, Illinois 60612, USA
    Clin Immunol 130:298-303. 2009
  10. pmc Risk factors for chronic kidney disease in a large cohort of HIV-1 infected individuals initiating antiretroviral therapy in routine care
    Robert C Kalayjian
    Metro Health Medical Center, Cleveland, Ohio, USA
    AIDS 26:1907-15. 2012

Detail Information

Publications16

  1. ncbi request reprint Kidney Disease in HIV-Infected Persons
    Robert C Kalayjian
    Division of Infectious Diseases, MetroHealth Medical Center, 2500 MetroHealth Dr, Cleveland, OH, 44109, USA
    Curr Infect Dis Rep 14:83-90. 2012
    ..Robust associations between proteinuria and cardiovascular disease imply that common mechanisms of vascular endothelial dysfunction may contribute to both processes...
  2. pmc Older HIV-infected patients on antiretroviral therapy have B-cell expansion and attenuated CD4 cell increases with immune activation reduction
    Robert C Kalayjian
    MetroHealth Medical Center, Cleveland, OH, USA
    AIDS 27:1563-71. 2013
    ..The contribution of immune activation to accelerated HIV-disease progression in older individuals has not been delineated...
  3. ncbi request reprint Age-related immune dysfunction in health and in human immunodeficiency virus (HIV) disease: association of age and HIV infection with naive CD8+ cell depletion, reduced expression of CD28 on CD8+ cells, and reduced thymic volumes
    Robert C Kalayjian
    MetroHealth Medical Center and Case Western Reserve University, Cleveland, Ohio, USA
    J Infect Dis 187:1924-33. 2003
    ..Because of their common association with age and HIV disease, naive CD8(+) cell depletion, diminished CD28 expression on CD8(+) cells, and reduced thymic volumes are possible correlates of the interaction of age with HIV disease...
  4. doi request reprint Renal issues in HIV infection
    Robert C Kalayjian
    Division of Infectious Diseases, MetroHealth Medical Center, Cleveland, OH 44109, USA
    Curr HIV/AIDS Rep 8:164-71. 2011
    ..The emerging experience with kidney transplantation also suggests this to be a viable option in selected patients...
  5. pmc Pretreatment levels of soluble cellular receptors and interleukin-6 are associated with HIV disease progression in subjects treated with highly active antiretroviral therapy
    Robert C Kalayjian
    MetroHealth Medical Center, Case Western Reserve University School of Medicine, Cleveland, Ohio 44109 1998, USA
    J Infect Dis 201:1796-805. 2010
    ....
  6. ncbi request reprint Distinct mechanisms of T cell reconstitution can be identified by estimating thymic volume in adult HIV-1 disease
    Robert C Kalayjian
    Division of Infectious Diseases, MetroHealth Medical Center and Case Western Reserve University, Cleveland, Ohio 44109 1998, USA
    J Infect Dis 192:1577-87. 2005
    ..We have attempted to identify factors associated with T cell reconstitution in response to highly active antiretroviral therapy...
  7. pmc Suppression of HIV-1 replication by antiretroviral therapy improves renal function in persons with low CD4 cell counts and chronic kidney disease
    Robert C Kalayjian
    Department of Medicine, MetroHealth Medical Center, Cleveland, Ohio, USA
    AIDS 22:481-7. 2008
    ..To examine the association between changes in glomerular filtration rates (GFR) and antiretroviral therapy (ART)-mediated suppression of plasma HIV-1 viremia...
  8. pmc The effects of HIV type-1 viral suppression and non-viral factors on quantitative proteinuria in the highly active antiretroviral therapy era
    Samir K Gupta
    Division of Infectious Diseases, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
    Antivir Ther 14:543-9. 2009
    ..Proteinuria is associated with progressive renal disease and overall mortality in HIV-infected patients; however, the prevalence and correlates of quantitative proteinuria in the highly active antiretroviral therapy era are unknown...
  9. pmc The effect of aging on T-regulatory cell frequency in HIV infection
    Allan R Tenorio
    Section of Infectious Diseases, Department of Medicine, Rush Medical College, 600 S Paulina Street, Suite 143 AAC, Chicago, Illinois 60612, USA
    Clin Immunol 130:298-303. 2009
    ..T-reg percentages are increased in the older HIV(+) population and may play a role in the accelerated disease progression seen in older HIV-infected persons...
  10. pmc Risk factors for chronic kidney disease in a large cohort of HIV-1 infected individuals initiating antiretroviral therapy in routine care
    Robert C Kalayjian
    Metro Health Medical Center, Cleveland, Ohio, USA
    AIDS 26:1907-15. 2012
    ....
  11. pmc Immunologic failure despite suppressive antiretroviral therapy is related to activation and turnover of memory CD4 cells
    Michael M Lederman
    Division of Infectious Diseases, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
    J Infect Dis 204:1217-26. 2011
    ..Failure to normalize CD4(+) T-cell numbers despite effective antiretroviral therapy is an important problem in human immunodeficiency virus (HIV) infection...
  12. pmc Frequencies of FoxP3+ naive T cells are related to both viral load and naive T cell proliferation responses in HIV disease
    Benigno Rodriguez
    Department of Medicine, Case Western Reserve University, Cleveland, OH, USA
    J Leukoc Biol 90:621-8. 2011
    ..These observations suggest that alterations in naïve T cell subset frequencies could contribute to naïve T cell dysfunction in HIV disease, but these alterations are not necessarily the result of chronic immune activation...
  13. pmc Older age is associated with peripheral blood expansion of naïve B cells in HIV-infected subjects on antiretroviral therapy
    Puja Van Epps
    Geriatric Research Center Clinical Core GRECC, Department of Infectious Diseases, Louis Stokes Cleveland VA Medical Center, Case Western Reserve University, Cleveland, Ohio, United States of America
    PLoS ONE 9:e107064. 2014
    ..Relationship between RM cells at baseline and tetanus responses may lead to insights about the effects of HIV infection on B cell memory function and vaccine responses. ..
  14. doi request reprint Impact of therapy and strain type on outcomes in urinary tract infections caused by carbapenem-resistant Klebsiella pneumoniae
    David van Duin
    Division of Infectious Diseases, University of North Carolina, Chapel Hill, NC, USA
    J Antimicrob Chemother 70:1203-11. 2015
    ..Carbapenem-resistant Klebsiella pneumoniae (CRKP) is an important healthcare-associated pathogen. We evaluated the impact of CRKP strain type and treatment on outcomes of patients with CRKP bacteriuria...
  15. pmc The treatment of HIV-associated nephropathy
    Robert C Kalayjian
    MetroHealth Medical Center and Case Western Reserve University School of Medicine, Cleveland, OH, USA
    Adv Chronic Kidney Dis 17:59-71. 2010
    ..Underexposure to ART or inadequate ART dosing in HIV-infected patients with CKD may curtail the optimal benefits that may be derived from this therapy...
  16. ncbi request reprint Virologic characterization of HIV type 1 with a codon 70 deletion in reverse transcriptase
    Zixin Hu
    Section of Retroviral Therapeutics, Brigham and Women s Hospital, and Division of AIDS, Harvard Medical School, Boston, MA, USA
    J Acquir Immune Defic Syndr 45:494-500. 2007
    ..These results show that Delta70 enhances resistance to certain purine and pyrimidine analogues and contributes to multinucleoside resistance in the appropriate viral genetic background...