Robert C Kalayjian

Summary

Affiliation: Case Western Reserve University
Country: USA

Publications

  1. ncbi request reprint Age-related immune dysfunction in health and in human immunodeficiency virus (HIV) disease: association of age and HIV infection with naive CD8+ cell depletion, reduced expression of CD28 on CD8+ cells, and reduced thymic volumes
    Robert C Kalayjian
    MetroHealth Medical Center and Case Western Reserve University, Cleveland, Ohio, USA
    J Infect Dis 187:1924-33. 2003
  2. ncbi request reprint Distinct mechanisms of T cell reconstitution can be identified by estimating thymic volume in adult HIV-1 disease
    Robert C Kalayjian
    Division of Infectious Diseases, MetroHealth Medical Center and Case Western Reserve University, Cleveland, Ohio 44109 1998, USA
    J Infect Dis 192:1577-87. 2005
  3. ncbi request reprint Kidney Disease in HIV-Infected Persons
    Robert C Kalayjian
    Division of Infectious Diseases, MetroHealth Medical Center, 2500 MetroHealth Dr, Cleveland, OH, 44109, USA
    Curr Infect Dis Rep 14:83-90. 2012
  4. pmc Suppression of HIV-1 replication by antiretroviral therapy improves renal function in persons with low CD4 cell counts and chronic kidney disease
    Robert C Kalayjian
    Department of Medicine, MetroHealth Medical Center, Cleveland, Ohio, USA
    AIDS 22:481-7. 2008
  5. doi request reprint Renal issues in HIV infection
    Robert C Kalayjian
    Division of Infectious Diseases, MetroHealth Medical Center, Cleveland, OH 44109, USA
    Curr HIV/AIDS Rep 8:164-71. 2011
  6. pmc Pretreatment levels of soluble cellular receptors and interleukin-6 are associated with HIV disease progression in subjects treated with highly active antiretroviral therapy
    Robert C Kalayjian
    MetroHealth Medical Center, Case Western Reserve University School of Medicine, Cleveland, Ohio 44109 1998, USA
    J Infect Dis 201:1796-805. 2010
  7. pmc The effects of HIV type-1 viral suppression and non-viral factors on quantitative proteinuria in the highly active antiretroviral therapy era
    Samir K Gupta
    Division of Infectious Diseases, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
    Antivir Ther 14:543-9. 2009
  8. pmc The effect of aging on T-regulatory cell frequency in HIV infection
    Allan R Tenorio
    Section of Infectious Diseases, Department of Medicine, Rush Medical College, 600 S Paulina Street, Suite 143 AAC, Chicago, Illinois 60612, USA
    Clin Immunol 130:298-303. 2009
  9. pmc Risk factors for chronic kidney disease in a large cohort of HIV-1 infected individuals initiating antiretroviral therapy in routine care
    Robert C Kalayjian
    Metro Health Medical Center, Cleveland, Ohio, USA
    AIDS 26:1907-15. 2012
  10. pmc Immunologic failure despite suppressive antiretroviral therapy is related to activation and turnover of memory CD4 cells
    Michael M Lederman
    Division of Infectious Diseases, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
    J Infect Dis 204:1217-26. 2011

Detail Information

Publications13

  1. ncbi request reprint Age-related immune dysfunction in health and in human immunodeficiency virus (HIV) disease: association of age and HIV infection with naive CD8+ cell depletion, reduced expression of CD28 on CD8+ cells, and reduced thymic volumes
    Robert C Kalayjian
    MetroHealth Medical Center and Case Western Reserve University, Cleveland, Ohio, USA
    J Infect Dis 187:1924-33. 2003
    ..Because of their common association with age and HIV disease, naive CD8(+) cell depletion, diminished CD28 expression on CD8(+) cells, and reduced thymic volumes are possible correlates of the interaction of age with HIV disease...
  2. ncbi request reprint Distinct mechanisms of T cell reconstitution can be identified by estimating thymic volume in adult HIV-1 disease
    Robert C Kalayjian
    Division of Infectious Diseases, MetroHealth Medical Center and Case Western Reserve University, Cleveland, Ohio 44109 1998, USA
    J Infect Dis 192:1577-87. 2005
    ..We have attempted to identify factors associated with T cell reconstitution in response to highly active antiretroviral therapy...
  3. ncbi request reprint Kidney Disease in HIV-Infected Persons
    Robert C Kalayjian
    Division of Infectious Diseases, MetroHealth Medical Center, 2500 MetroHealth Dr, Cleveland, OH, 44109, USA
    Curr Infect Dis Rep 14:83-90. 2012
    ..Robust associations between proteinuria and cardiovascular disease imply that common mechanisms of vascular endothelial dysfunction may contribute to both processes...
  4. pmc Suppression of HIV-1 replication by antiretroviral therapy improves renal function in persons with low CD4 cell counts and chronic kidney disease
    Robert C Kalayjian
    Department of Medicine, MetroHealth Medical Center, Cleveland, Ohio, USA
    AIDS 22:481-7. 2008
    ..To examine the association between changes in glomerular filtration rates (GFR) and antiretroviral therapy (ART)-mediated suppression of plasma HIV-1 viremia...
  5. doi request reprint Renal issues in HIV infection
    Robert C Kalayjian
    Division of Infectious Diseases, MetroHealth Medical Center, Cleveland, OH 44109, USA
    Curr HIV/AIDS Rep 8:164-71. 2011
    ..The emerging experience with kidney transplantation also suggests this to be a viable option in selected patients...
  6. pmc Pretreatment levels of soluble cellular receptors and interleukin-6 are associated with HIV disease progression in subjects treated with highly active antiretroviral therapy
    Robert C Kalayjian
    MetroHealth Medical Center, Case Western Reserve University School of Medicine, Cleveland, Ohio 44109 1998, USA
    J Infect Dis 201:1796-805. 2010
    ....
  7. pmc The effects of HIV type-1 viral suppression and non-viral factors on quantitative proteinuria in the highly active antiretroviral therapy era
    Samir K Gupta
    Division of Infectious Diseases, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
    Antivir Ther 14:543-9. 2009
    ..Proteinuria is associated with progressive renal disease and overall mortality in HIV-infected patients; however, the prevalence and correlates of quantitative proteinuria in the highly active antiretroviral therapy era are unknown...
  8. pmc The effect of aging on T-regulatory cell frequency in HIV infection
    Allan R Tenorio
    Section of Infectious Diseases, Department of Medicine, Rush Medical College, 600 S Paulina Street, Suite 143 AAC, Chicago, Illinois 60612, USA
    Clin Immunol 130:298-303. 2009
    ..T-reg percentages are increased in the older HIV(+) population and may play a role in the accelerated disease progression seen in older HIV-infected persons...
  9. pmc Risk factors for chronic kidney disease in a large cohort of HIV-1 infected individuals initiating antiretroviral therapy in routine care
    Robert C Kalayjian
    Metro Health Medical Center, Cleveland, Ohio, USA
    AIDS 26:1907-15. 2012
    ....
  10. pmc Immunologic failure despite suppressive antiretroviral therapy is related to activation and turnover of memory CD4 cells
    Michael M Lederman
    Division of Infectious Diseases, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
    J Infect Dis 204:1217-26. 2011
    ..Failure to normalize CD4(+) T-cell numbers despite effective antiretroviral therapy is an important problem in human immunodeficiency virus (HIV) infection...
  11. pmc Frequencies of FoxP3+ naive T cells are related to both viral load and naive T cell proliferation responses in HIV disease
    Benigno Rodriguez
    Department of Medicine, Case Western Reserve University, Cleveland, OH, USA
    J Leukoc Biol 90:621-8. 2011
    ..These observations suggest that alterations in naïve T cell subset frequencies could contribute to naïve T cell dysfunction in HIV disease, but these alterations are not necessarily the result of chronic immune activation...
  12. pmc The treatment of HIV-associated nephropathy
    Robert C Kalayjian
    MetroHealth Medical Center and Case Western Reserve University School of Medicine, Cleveland, OH, USA
    Adv Chronic Kidney Dis 17:59-71. 2010
    ..Underexposure to ART or inadequate ART dosing in HIV-infected patients with CKD may curtail the optimal benefits that may be derived from this therapy...
  13. ncbi request reprint Virologic characterization of HIV type 1 with a codon 70 deletion in reverse transcriptase
    Zixin Hu
    Section of Retroviral Therapeutics, Brigham and Women s Hospital, and Division of AIDS, Harvard Medical School, Boston, MA, USA
    J Acquir Immune Defic Syndr 45:494-500. 2007
    ..These results show that Delta70 enhances resistance to certain purine and pyrimidine analogues and contributes to multinucleoside resistance in the appropriate viral genetic background...