Keming Gao

Summary

Affiliation: Case Western Reserve University
Country: USA

Publications

  1. pmc Correlates of historical suicide attempt in rapid-cycling bipolar disorder: a cross-sectional assessment
    Keming Gao
    Department of Psychiatry, Case Western University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio, USA
    J Clin Psychiatry 70:1032-40. 2009
  2. ncbi request reprint Newer treatment studies for bipolar depression
    Keming Gao
    NIMH Bipolar Research Center, Mood Disorders Program, University Hospitals of Cleveland Case Western Reserve University School of Medicine, Cleveland, OH, USA
    Bipolar Disord 7:13-23. 2005
  3. ncbi request reprint Typical and atypical antipsychotics in bipolar depression
    Keming Gao
    Mood Disorders Program, Department of Psychiatry, University Hospitals of Cleveland, Case Western Reserve University School of Medicine, 11400 Euclid Avenue, Cleveland, OH 44106, USA
    J Clin Psychiatry 66:1376-85. 2005
  4. ncbi request reprint Efficacy of typical and atypical antipsychotics for primary and comorbid anxiety symptoms or disorders: a review
    Keming Gao
    Department of Psychiatry, the Bipolar Disorders Research Center, University Hospitals of Cleveland Case Western Reserve University, School of Medicine, Cleveland, Ohio, USA
    J Clin Psychiatry 67:1327-40. 2006
  5. ncbi request reprint Clinical correlates of patients with rapid-cycling bipolar disorder and a recent history of substance use disorder: a subtype comparison from baseline data of 2 randomized, placebo-controlled trials
    Keming Gao
    Department of Psychiatry, Bipolar Disorder Research Center at the Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA
    J Clin Psychiatry 69:1057-63. 2008
  6. doi request reprint Treatment-emergent mania/hypomania during antidepressant monotherapy in patients with rapid cycling bipolar disorder
    Keming Gao
    Department of Psychiatry, Bipolar Disorder Research Center at Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, 10524 Euclid Avenue, Cleveland, OH 44106, USA
    Bipolar Disord 10:907-15. 2008
  7. pmc A 6-month, double-blind, maintenance trial of lithium monotherapy versus the combination of lithium and divalproex for rapid-cycling bipolar disorder and Co-occurring substance abuse or dependence
    David E Kemp
    Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, Ohio, USA
    J Clin Psychiatry 70:113-21. 2009
  8. pmc Lamotrigine adjunctive therapy to lithium and divalproex in depressed patients with rapid cycling bipolar disorder and a recent substance use disorder: a 12-week, double-blind, placebo-controlled pilot study
    Zuowei Wang
    Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, OH, USA
    Psychopharmacol Bull 43:5-21. 2010
  9. pmc Medical and substance use comorbidity in bipolar disorder
    David E Kemp
    Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH, USA
    J Affect Disord 116:64-9. 2009
  10. pmc Predictors of non-stabilization during the combination therapy of lithium and divalproex in rapid cycling bipolar disorder: a post-hoc analysis of two studies
    Keming Gao
    Department of Psychiatry, Case Western Reserve University, Cleveland, OH, USA
    Psychopharmacol Bull 43:23-38. 2010

Detail Information

Publications31

  1. pmc Correlates of historical suicide attempt in rapid-cycling bipolar disorder: a cross-sectional assessment
    Keming Gao
    Department of Psychiatry, Case Western University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio, USA
    J Clin Psychiatry 70:1032-40. 2009
    ..A rapid-cycling course in bipolar disorder has previously been identified as a risk factor for attempted suicide. This study investigated factors associated with suicide attempts in patients with rapid-cycling bipolar I or II disorder...
  2. ncbi request reprint Newer treatment studies for bipolar depression
    Keming Gao
    NIMH Bipolar Research Center, Mood Disorders Program, University Hospitals of Cleveland Case Western Reserve University School of Medicine, Cleveland, OH, USA
    Bipolar Disord 7:13-23. 2005
    ..Depressive symptoms of bipolar disorder have more negative impact on a patient's life than manic symptoms. This review focused on the emerging efficacy data for treatments in bipolar depression...
  3. ncbi request reprint Typical and atypical antipsychotics in bipolar depression
    Keming Gao
    Mood Disorders Program, Department of Psychiatry, University Hospitals of Cleveland, Case Western Reserve University School of Medicine, 11400 Euclid Avenue, Cleveland, OH 44106, USA
    J Clin Psychiatry 66:1376-85. 2005
    ..Since the antipsychotic agents have been shown to diminish depressive symptoms during the treatment of mania, atypical agents are now being studied for use in bipolar depression...
  4. ncbi request reprint Efficacy of typical and atypical antipsychotics for primary and comorbid anxiety symptoms or disorders: a review
    Keming Gao
    Department of Psychiatry, the Bipolar Disorders Research Center, University Hospitals of Cleveland Case Western Reserve University, School of Medicine, Cleveland, Ohio, USA
    J Clin Psychiatry 67:1327-40. 2006
    ..The efficacy of antipsychotics in the treatment of primary or comorbid anxiety disorders or anxiety symptoms in major depressive disorder or bipolar disorder was reviewed...
  5. ncbi request reprint Clinical correlates of patients with rapid-cycling bipolar disorder and a recent history of substance use disorder: a subtype comparison from baseline data of 2 randomized, placebo-controlled trials
    Keming Gao
    Department of Psychiatry, Bipolar Disorder Research Center at the Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA
    J Clin Psychiatry 69:1057-63. 2008
    ..To compare clinical variables in patients with rapid-cycling bipolar I or II disorder and a recent history of substance use disorder (SUD)...
  6. doi request reprint Treatment-emergent mania/hypomania during antidepressant monotherapy in patients with rapid cycling bipolar disorder
    Keming Gao
    Department of Psychiatry, Bipolar Disorder Research Center at Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, 10524 Euclid Avenue, Cleveland, OH 44106, USA
    Bipolar Disord 10:907-15. 2008
    ..To study treatment-emergent mania/hypomania (TEM) associated with second-generation antidepressant monotherapy in patients with rapid cycling bipolar disorder (RCBD)...
  7. pmc A 6-month, double-blind, maintenance trial of lithium monotherapy versus the combination of lithium and divalproex for rapid-cycling bipolar disorder and Co-occurring substance abuse or dependence
    David E Kemp
    Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, Ohio, USA
    J Clin Psychiatry 70:113-21. 2009
    ....
  8. pmc Lamotrigine adjunctive therapy to lithium and divalproex in depressed patients with rapid cycling bipolar disorder and a recent substance use disorder: a 12-week, double-blind, placebo-controlled pilot study
    Zuowei Wang
    Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, OH, USA
    Psychopharmacol Bull 43:5-21. 2010
    ..To pilot the efficacy and safety data of lamotrigine adjunctive therapy to lithium and divalproex in patients with rapid-cycling bipolar disorder (RCBD) and a recent substance use disorder (SUD)...
  9. pmc Medical and substance use comorbidity in bipolar disorder
    David E Kemp
    Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH, USA
    J Affect Disord 116:64-9. 2009
    ....
  10. pmc Predictors of non-stabilization during the combination therapy of lithium and divalproex in rapid cycling bipolar disorder: a post-hoc analysis of two studies
    Keming Gao
    Department of Psychiatry, Case Western Reserve University, Cleveland, OH, USA
    Psychopharmacol Bull 43:23-38. 2010
    ....
  11. ncbi request reprint Clinical highlights in bipolar depression: focus on atypical antipsychotics
    Joseph R Calabrese
    University Hospitals of Cleveland Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
    J Clin Psychiatry 66:26-33. 2005
    ..In addition, direct comparison of the regimens used in the current study should determine whether the differences evident between them can be confirmed...
  12. pmc Independent predictors for lifetime and recent substance use disorders in patients with rapid-cycling bipolar disorder: focus on anxiety disorders
    Keming Gao
    Department of Psychiatry, Bipolar Disorder Research Center at Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA
    Am J Addict 19:440-9. 2010
    ....
  13. pmc Lamotrigine as add-on treatment to lithium and divalproex: lessons learned from a double-blind, placebo-controlled trial in rapid-cycling bipolar disorder
    David E Kemp
    Department of Psychiatry, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH 44106, USA
    Bipolar Disord 14:780-9. 2012
    ..This study assessed the antidepressant effects of lamotrigine as compared with placebo when used as add-on therapy for rapid-cycling bipolar depression non-responsive to the combination of lithium plus divalproex...
  14. pmc Medical comorbidity in bipolar disorder: relationship between illnesses of the endocrine/metabolic system and treatment outcome
    David E Kemp
    Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH 44106, USA
    Bipolar Disord 12:404-13. 2010
    ..It was hypothesized that illnesses of the endocrine/metabolic system would be associated with greater psychiatric symptom burden and would impact the response to treatment with lithium and valproate...
  15. pmc Differential interactions between comorbid anxiety disorders and substance use disorder in rapid cycling bipolar I or II disorder
    Keming Gao
    Department of Psychiatry, Bipolar Disorder Research Center at Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio, USA
    J Affect Disord 110:167-73. 2008
    ..Anxiety disorders (AD) and substance use disorders (SUD) commonly co-occur with bipolar disorder. This study was undertaken to assess AD-SUD-bipolar subtype interactions...
  16. ncbi request reprint A review of sensitivity and tolerability of antipsychotics in patients with bipolar disorder or schizophrenia: focus on somnolence
    Keming Gao
    Department of Psychiatry, Bipolar Disorder Research Center at Mood Disorders Program, University Hospitals Case Medical Center Case Western Reserve University, School of Medicine, Cleveland, Ohio, USA
    J Clin Psychiatry 69:302-9. 2008
    ..This study compared the sensitivity and tolerability of antipsychotics in patients with bipolar disorder or schizophrenia...
  17. doi request reprint Acute efficacy of divalproex sodium versus placebo in mood stabilizer-naive bipolar I or II depression: a double-blind, randomized, placebo-controlled trial
    David J Muzina
    Department of Psychiatry and Psychology, Neurological Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    J Clin Psychiatry 72:813-9. 2011
    ..To conduct an exploratory evaluation of the acute efficacy of extended-release divalproex sodium compared to placebo in patients with bipolar I or II depression...
  18. pmc Number needed to treat to harm for discontinuation due to adverse events in the treatment of bipolar depression, major depressive disorder, and generalized anxiety disorder with atypical antipsychotics
    Keming Gao
    Department of Psychiatry, Mood and Anxiety Clinic in the Mood Disorders Program, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
    J Clin Psychiatry 72:1063-71. 2011
    ....
  19. doi request reprint Risk for adverse events and discontinuation due to adverse events of ziprasidone monotherapy relative to placebo in the acute treatment of bipolar depression, mania, and schizophrenia
    Keming Gao
    Mood and Anxiety Clinic in the Mood Disorders Program of the Department of Psychiatry, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH 44106, USA
    J Clin Psychopharmacol 33:425-31. 2013
    ....
  20. doi request reprint Should an assessment of Axis I comorbidity be included in the initial diagnostic assessment of mood disorders? Role of QIDS-16-SR total score in predicting number of Axis I comorbidity
    Keming Gao
    Mood and Anxiety Clinic in the Mood Disorders Program of Department of Psychiatry, Case Western Reserve University School of Medicine University Hospitals Case Medical Center, 10524 Euclid Avenue, 12th Floor, Cleveland, OH 44016, USA
    J Affect Disord 148:256-64. 2013
    ....
  21. pmc Use of insulin sensitizers for the treatment of major depressive disorder: a pilot study of pioglitazone for major depression accompanied by abdominal obesity
    David E Kemp
    Case Western Reserve University, University Hospitals Case Medical Center, Department of Psychiatry, Cleveland, OH 44106, USA
    J Affect Disord 136:1164-73. 2012
    ..This study was conducted to examine the safety and efficacy of pioglitazone, a thiazolidinedione insulin sensitizer, in adult outpatients with major depressive disorder...
  22. ncbi request reprint Treatment-emergent mania in unipolar and bipolar depression: focus on repetitive transcranial magnetic stimulation
    Guohua Xia
    Department of Psychiatry, Case Western Reserve University, Cleveland, OH 44106, USA
    Int J Neuropsychopharmacol 11:119-30. 2008
    ..More systematic studies are needed to better understand TEM associated with rTMS. Special precautions and measures should be adopted to prevent, monitor, and manage TEM in research and practice...
  23. pmc Antipsychotic-induced extrapyramidal side effects in bipolar disorder and schizophrenia: a systematic review
    Keming Gao
    Department of Psychiatry, Bipolar Disorder Research Center at the Mood Disorders Program, University Hospitals Case Medical Center Case Western Reserve University, School of Medicine, Cleveland, OH, USA
    J Clin Psychopharmacol 28:203-9. 2008
    ..This review is to compare antipsychotic-induced EPS relative to placebo in bipolar disorder (BPD) and schizophrenia...
  24. doi request reprint Safety and efficacy of olanzapine monotherapy in treatment-resistant bipolar mania: a 12-week open-label study
    Jun Chen
    Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University, School of Medicine, Shanghai, China
    Hum Psychopharmacol 26:588-95. 2011
    ..To examine the safety and efficacy of olanzapine monotherapy in treatment-resistant bipolar mania...
  25. ncbi request reprint Acute treatment of mania: an update on new medications
    Prashant Gajwani
    Case School of Medicine, Mood Disorders Program, University Hospitals Case Medical Center, 11400 Euclid Avenue, Suite 200, Cleveland, OH 44106, USA
    Curr Psychiatry Rep 8:504-9. 2006
    ....
  26. doi request reprint Communication of potential benefits and harm to patients and payers in psychiatry: a review and commentary
    Renrong Wu
    Department of Psychiatry, Mood and Anxiety Clinic in Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio, USA
    Clin Ther 33:B62-76. 2011
    ..Communicating potential benefits and harm to patients and payers is essential for high-quality care. However, there are no published guidelines or consensuses on how to communicate potential benefits and harm to patients and payers...
  27. ncbi request reprint Antiepileptic drugs in mood-disordered patients
    Prashant Gajwani
    NIMH Bipolar Research Center, Case Western Reserve University School of Medicine, Mood Disorders Program, University Hospitals of Cleveland, OH, USA
    Epilepsia 46:38-44. 2005
    ..LTG seems to be effective against depression and mania, with a more robust activity against depression. No firm evidence supports a role for vigabatrin, tiagabine, topiramate, or levetiracetam in these disorders...
  28. ncbi request reprint PPAR-γ Agonism as a Modulator of Mood: Proof-of-Concept for Pioglitazone in Bipolar Depression
    David E Kemp
    University Hospitals Case Medical Center, Case Western Reserve University, 10524 Euclid Ave, 12th Floor, Cleveland, OH, 44106, USA
    CNS Drugs 28:571-81. 2014
    ..A secondary objective was to determine whether levels of highly sensitive C-reactive protein and interleukin (IL)-6 predicted treatment outcome...
  29. doi request reprint Switching to hypomania and mania: differential neurochemical, neuropsychological, and pharmacologic triggers and their mechanisms
    Jun Chen
    Department of Psychiatry, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, OH 44106, USA
    Curr Psychiatry Rep 12:512-21. 2010
    ..Venlafaxine was shown to have an increased risk of TEM compared with bupropion and sertraline. The evolving literature continues to support the role of mood stabilizers in preventing future mood episodes of BPD...
  30. pmc Atypical antipsychotics in primary generalized anxiety disorder or comorbid with mood disorders
    Keming Gao
    Department of Psychiatry, Mood and Anxiety Clinic in the Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, OH 44106, USA
    Expert Rev Neurother 9:1147-58. 2009
    ..However, in contrast to antidepressants and benzodiazepines, the long-term risk and benefit of atypical antipsychotics in the treatment of GAD is yet to be determined...
  31. ncbi request reprint Awareness under anesthesia during electroconvulsive therapy treatment
    Prashant Gajwani
    Case School of Medicine, Cleveland, OH 44106, USA
    J ECT 22:158-9. 2006
    ....