Research Topics
| Avroy A FanaroffSummaryAffiliation: Case Western Reserve University Country: USA Publications
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Detail Information
Publications
The NICHD neonatal research network: changes in practice and outcomes during the first 15 yearsAvroy A Fanaroff
Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH, USA
Semin Perinatol 27:281-7. 2003..Advances in perinatal care within NICHD Network centers have resulted in marked improvements in survival. Further advances are required to increase survival free of neonatal morbidity or neurodevelopmental impairment...
Short- and long-term consequences of hypotension in ELBW infantsAvroy A Fanaroff
Department of Pediatrics, Case Western Reserve University School of Medicine, Case Western Reserve University School of Medicine, Rainbow Babies and Children s Hospital, 11100 Euclid Avenue, Cleveland, OH 44106, USA
Semin Perinatol 30:151-5. 2006....
Outcome of term infants using apgar scores at 10 minutes following hypoxic-ischemic encephalopathyAbbot R Laptook
Department of Pediatrics, Women and Infants Hospital of Rhode Island, Providence, Rhode Island 02906, USA
Pediatrics 124:1619-26. 2009..The objective of this study was to determine whether Apgar scores at 10 minutes are associated with death or disability in early childhood after perinatal hypoxic-ischemic encephalopathy...
Trends in neonatal morbidity and mortality for very low birthweight infantsAvroy A Fanaroff
Department of Pediatrics, Case Western Reserve University, Cleveland, OH
Am J Obstet Gynecol 196:147.e1-8. 2007..To document the mortality and morbidity of infants weighing 501-1500 g at birth according to gestational age, birthweight, and sex...
Cytokines and neurodevelopmental outcomes in extremely low birth weight infantsWaldemar A Carlo
Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233 7335, USA
J Pediatr 159:919-25.e3. 2011....
Predicting time to hospital discharge for extremely preterm infantsSusan R Hintz
Department of Pediatrics, Division of Neonatology, Stanford University School of Medicine and Lucile Packard Children s Hospital, Palo Alto, CA 94304, USA
Pediatrics 125:e146-54. 2010..Accurate models for predicting time to hospital discharge could aid in resource planning, family counseling, and stimulate quality-improvement initiatives...
Association of antenatal corticosteroids with mortality and neurodevelopmental outcomes among infants born at 22 to 25 weeks' gestationWaldemar A Carlo
Department of Pediatrics, University of Alabama, 9380 Women and Infants Center, 1700 Sixth Ave S, Birmingham, AL 35249, USA
JAMA 306:2348-58. 2011..However, many infants born before 24 weeks' gestation are provided intensive care...
Extremely low birthweight neonates with protracted ventilation: mortality and 18-month neurodevelopmental outcomesMichele C Walsh
Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio, USA
J Pediatr 146:798-804. 2005..To compare duration of ventilation to mortality and adverse neurodevelopmental outcomes among extremely low birth weight (ELBW; 501-1000 g) infants...
Outcomes of safety and effectiveness in a multicenter randomized, controlled trial of whole-body hypothermia for neonatal hypoxic-ischemic encephalopathySeetha Shankaran
Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan, USA
Pediatrics 122:e791-8. 2008..Whole-body hypothermia reduced the frequency of death or moderate/severe disabilities in neonates with hypoxic-ischemic encephalopathy in a randomized, controlled multicenter trial...
Synchronized nasal intermittent positive-pressure ventilation and neonatal outcomesVineet Bhandari
Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520 8064, USA
Pediatrics 124:517-26. 2009..Limited information is available on the outcomes of infants managed with SNIPPV...
Impact of timing of birth and resident duty-hour restrictions on outcomes for small preterm infantsEdward F Bell
Department of Pediatrics, University of Iowa, Iowa City, IA 52242, USA
Pediatrics 126:222-31. 2010....
Early nutrition mediates the influence of severity of illness on extremely LBW infantsRichard A Ehrenkranz
Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA
Pediatr Res 69:522-9. 2011....
Predictive value of an early amplitude integrated electroencephalogram and neurologic examinationSeetha Shankaran
Department of Pediatrics, Wayne State University, Detroit, Michigan, USA
Pediatrics 128:e112-20. 2011..To examine the predictive validity of the amplitude integrated electroencephalogram (aEEG) and stage of encephalopathy among infants with hypoxic-ischemic encephalopathy (HIE) eligible for therapeutic whole-body hypothermia...
Early-childhood neurodevelopmental outcomes are not improving for infants born at <25 weeks' gestational ageSusan R Hintz
Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, 750 Welch Rd, Suite 315, Palo Alto, CA 94304, USA
Pediatrics 127:62-70. 2011..We compared neurodevelopmental outcomes at 18 to 22 months' corrected age of infants born with extremely low birth weight at an estimated gestational age of <25 weeks during 2 periods: 1999-2001 (epoch 1) and 2002-2004 (epoch 2)...
To tap or not to tap: high likelihood of meningitis without sepsis among very low birth weight infantsBarbara J Stoll
Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA
Pediatrics 113:1181-6. 2004..Because CSF cultures were performed only half as often as BCs, this discordance in blood and CSF culture results suggests that meningitis may be underdiagnosed among VLBW infants...
Validation of the National Institutes of Health consensus definition of bronchopulmonary dysplasiaRichard A Ehrenkranz
Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
Pediatrics 116:1353-60. 2005..The objective of this study was to determine the predictive validity of the severity-based, consensus definition of BPD...
Very low birth weight preterm infants with surgical short bowel syndrome: incidence, morbidity and mortality, and growth outcomes at 18 to 22 monthsConrad R Cole
Emory University School of Medicine, Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, 2015 Uppergate Dr, Atlanta, GA 30322, USA
Pediatrics 122:e573-82. 2008....
Community supports after surviving extremely low-birth-weight, extremely preterm birth: special outpatient services in early childhoodSusan R Hintz
Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California 94304, USA
Arch Pediatr Adolesc Med 162:748-55. 2008..To determine special outpatient services (SOS) use, need, associated factors, and neurodevelopmental and functional outcomes among extremely preterm infants at 18 to 22 months' corrected age...
Neurodevelopmental and growth outcomes of extremely low birth weight infants after necrotizing enterocolitisSusan R Hintz
Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, 750 Welch Rd, Suite 315, Palo Alto, CA 94304, USA
Pediatrics 115:696-703. 2005..The objective of this study was to compare growth, neurologic, and cognitive outcomes among ELBW survivors of SurgNEC and MedNEC with NoNEC at 18 to 22 months' corrected age...
Prediction of bronchopulmonary dysplasia by postnatal age in extremely premature infantsMatthew M Laughon
Department of Pediatrics, University of North Carolina, Chapel Hill, North Carolina 27599 7596, USA
Am J Respir Crit Care Med 183:1715-22. 2011....
Stability of neuromotor outcomes at 18 and 30 months of age after extremely low birth weight statusMyriam Peralta-Carcelen
Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, USA
Pediatrics 123:e887-95. 2009..Extremely low birth weight (< or =1000 g) children have increased rates of cerebral palsy and other abnormal neurologic findings...
Survival and morbidity outcomes for very low birth weight infants with Down syndromeNansi S Boghossian
University of Iowa Health Care, Department of Pediatrics, 200 Hawkins Dr, Iowa City, IA 52242, USA
Pediatrics 126:1132-40. 2010....
Neonatal outcomes of extremely preterm infants from the NICHD Neonatal Research NetworkBarbara J Stoll
Department of Pediatrics, Emory University School of Medicine and Children s Healthcare of Atlanta, 2015 Uppergate Dr, Atlanta, GA 30322, USA
Pediatrics 126:443-56. 2010....
Cytokines associated with bronchopulmonary dysplasia or death in extremely low birth weight infantsNamasivayam Ambalavanan
Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35249, USA
Pediatrics 123:1132-41. 2009..The goal was to develop multivariate logistic regression models for the outcome of bronchopulmonary dysplasia and/or death at postmenstrual age of 36 weeks by using clinical and cytokine data from the first 28 days...
Maternal age, multiple birth, and extremely low birth weight infantsBetty R Vohr
Department of Pediatrics, The Warren Alpert Medical School of Brown University, Providence, RI, USA
J Pediatr 154:498-503.e2. 2009..To compare the rates of adverse neurodevelopmental outcome or death at 18 to 22 months among extremely low birth weight (ELBW) infants born to mothers >or=4 0 years to the corresponding rates among infants of younger mothers...
Prediction of death for extremely low birth weight neonatesNamasivayam Ambalavanan
Department of Pediatrics, University of Alabama, Birmingham, AL 35249, USA
Pediatrics 116:1367-73. 2005....
Antenatal consent in the SUPPORT trial: challenges, costs, and representative enrollmentWade D Rich
Department of Pediatrics, School of Medicine, University of California, San Diego, California, USA
Pediatrics 126:e215-21. 2010....
Parenteral glutamine supplementation does not reduce the risk of mortality or late-onset sepsis in extremely low birth weight infantsBrenda B Poindexter
Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA
Pediatrics 113:1209-15. 2004..Whether glutamine supplementation would provide a similar benefit to extremely low birth weight (ELBW) infants is not known...
Intercenter differences in bronchopulmonary dysplasia or death among very low birth weight infantsNamasivayam Ambalavanan
Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35249, USA
Pediatrics 127:e106-16. 2011....
Hypocarbia and adverse outcome in neonatal hypoxic-ischemic encephalopathyAthina Pappas
Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI 48201, USA
J Pediatr 158:752-758.e1. 2011..To evaluate the association between early hypocarbia and 18- to 22-month outcome among neonates with hypoxic-ischemic encephalopathy...
T cell cytokines and the risk of blood stream infection in extremely low birth weight infantsRobert L Schelonka
Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA
Cytokine 53:249-55. 2011..Altered maturation of regulatory and inflammatory cytokines may increase the risk of serious infection in this population...
Very low birth weight preterm infants with early onset neonatal sepsis: the predominance of gram-negative infections continues in the National Institute of Child Health and Human Development Neonatal Research Network, 2002-2003Barbara J Stoll
Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA
Pediatr Infect Dis J 24:635-9. 2005..CONCLUSION: EOS remains an uncommon but important cause of morbidity and mortality among VLBW infants. Gram-negative organisms continue to be the predominant pathogens associated with EOS...
Improved survival rates with increased neurodevelopmental disability for extremely low birth weight infants in the 1990sDeanne Wilson-Costello
Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio, USA
Pediatrics 115:997-1003. 2005....
Treated hypotension is associated with neonatal morbidity and hearing loss in extremely low birth weight infantsJonathan M Fanaroff
Department of Pediatrics, Rainbow Babies and Children s Hospital, Case Western Reserve University, Cleveland, Ohio, USA
Pediatrics 117:1131-5. 2006..Neonatal hypotension may be a risk factor for neurologic impairment. Few studies have examined the impact of low blood pressure in extremely low birth weight (ELBW) infants weighing 400 to 999 g on neurodevelopmental outcome...
Prolonged duration of initial empirical antibiotic treatment is associated with increased rates of necrotizing enterocolitis and death for extremely low birth weight infantsC Michael Cotten
Department of Pediatrics, Duke University, Durham, NC 27710, USA
Pediatrics 123:58-66. 2009....
Prolonged hospital stay for extremely premature infants: risk factors, center differences, and the impact of mortality on selecting a best-performing centerC Michael Cotten
Department of Pediatrics, Duke University School of Medicine, Durham, NC 27710, USA
J Perinatol 25:650-5. 2005..CONCLUSIONS: These findings suggest that reduction of CLD, surgical NEC, and late onset sepsis could reduce PHS in EP infants. Risk adjusted odds of PHS and mortality are both crucial for selecting a PHS best-performing center...
Perinatal systemic inflammatory response syndrome and retinopathy of prematurityBeena G Sood
Department of Pediatrics, Wayne State University, Detroit, Michigan 48201, USA
Pediatr Res 67:394-400. 2010..We conclude that perinatal inflammation may be involved in the pathogenesis of ROP...
Neurodevelopmental and growth impairment among extremely low-birth-weight infants with neonatal infectionBarbara J Stoll
Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA
JAMA 292:2357-65. 2004..Additional studies are needed to elucidate the pathogenesis of brain injury in infants with infection so that novel interventions to improve these outcomes can be explored...
Elevated temperature after hypoxic-ischemic encephalopathy: risk factor for adverse outcomesAbbot Laptook
Department of Pediatrics, Women and Infants Hospital of Rhode Island, 101 Dudley St, Providence, RI 02906, USA
Pediatrics 122:491-9. 2008....
Delivery room continuous positive airway pressure/positive end-expiratory pressure in extremely low birth weight infants: a feasibility trialNeil N Finer
Department of Pediatrics, University of California, 200 W Arbor Dr, 8774, San Diego, CA 92103 8774, USA
Pediatrics 114:651-7. 2004....
Enterobacter sakazakii is a rare cause of neonatal septicemia or meningitis in VLBW infantsBarbara J Stoll
Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA
J Pediatr 144:821-3. 2004..Only one case of ES sepsis was identified among 10660 neonates. These data suggest that outside of the epidemic situation, ES is very rare in very low birth weight infants...
Blood pressure disorders in the neonate: hypotension and hypertensionJonathan M Fanaroff
Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
Semin Fetal Neonatal Med 11:174-81. 2006..Hypertension, most often caused by congenital or acquired renovascular disease or volume overload, needs a thorough search for the etiology and cautious treatment, so that blood pressure does not fall too quickly or too low...
Predictors of death or bronchopulmonary dysplasia in preterm infants with respiratory failureN Ambalavanan
Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35249, USA
J Perinatol 28:420-6. 2008..To identify the variables that predict death/physiologic bronchopulmonary dysplasia (BPD) in preterm infants with severe respiratory failure...
Extremely low birthweight infants--the interplay between outcomes and ethicsAvroy A Fanaroff
Department of Pediatrics, Rainbow Babies and Children's Hospital, 11100 Euclid Ave, Cleveland, Ohio 44106, USA
Acta Paediatr 97:144-5. 2008
Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research NetworkBarbara J Stoll
Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA
Pediatrics 110:285-91. 2002..Strategies to reduce late-onset sepsis and its medical, social, and economic toll need to be addressed urgently...
Changes in pathogens causing early-onset sepsis in very-low-birth-weight infantsBarbara J Stoll
Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA
N Engl J Med 347:240-7. 2002..The change in pathogens over time from predominantly gram-positive to predominantly gram-negative requires confirmation by ongoing surveillance...
Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathySeetha Shankaran
Division of Neonatal Perinatal Medicine, Wayne State University, Children s Hospital of Michigan, Detroit, MI 48201, USA
N Engl J Med 353:1574-84. 2005..Hypothermia is protective against brain injury after asphyxiation in animal models. However, the safety and effectiveness of hypothermia in term infants with encephalopathy is uncertain...
Outcome of extremely-low-birth-weight infants at highest risk: gestational age < or =24 weeks, birth weight < or =750 g, and 1-minute Apgar < or =3Seetha Shankaran
Wayne State University, Detroit, MI, USA
Am J Obstet Gynecol 191:1084-91. 2004....
Risk factors for early death among extremely low-birth-weight infantsSeetha Shankaran
Wayne State University, Detroit, Michigan, USA
Am J Obstet Gynecol 186:796-802. 2002..4; 95% CI, 1.3-1.6), and lower birth weight per 50 g (95% CI, 1.2-1.4). CONCLUSION: Early death (<12 hours of age) among extremely low-birth-weight infants may reflect an assessment of non-viability by obstetricians and neonatologists...
Effect of parenteral glutamine supplementation on plasma amino acid concentrations in extremely low-birth-weight infantsBrenda B Poindexter
Indiana University, Indianapolis, USA
Am J Clin Nutr 77:737-43. 2003..Currently available amino acid solutions are likely to be suboptimal in their supply of phenylalanine, tyrosine, or both for these infants...
Association between peak serum bilirubin and neurodevelopmental outcomes in extremely low birth weight infantsWilliam Oh
Women and Infants Hospital of Rhode Island Brown University, Providence, Rhode Island 02905, USA
Pediatrics 112:773-9. 2003..To assess the association between peak total serum bilirubin (PSB) levels during the first 2 weeks of life and neurodevelopmental outcomes of extremely low birth weight (ELBW) infants at 18 to 22 months' postmenstrual age...
Neurodevelopmental outcome of premature infants after antenatal phenobarbital exposureSeetha Shankaran
Wayne State University, Detroit, MI, USA
Am J Obstet Gynecol 187:171-7. 2002....
Trends in mortality and morbidity for very low birth weight infants, 1991-1999Jeffrey D Horbar
University of Vermont Department of Pediatrics, Burlington, Vermont Vermont Oxford Network, Burlington, Vermont, USA
Pediatrics 110:143-51. 2002..Medical care for very low birth weight (VLBW) infants and their mothers has changed dramatically during the 1990s, yet it is unclear how these changes have affected mortality and morbidity...
Does labor influence neonatal and neurodevelopmental outcomes of extremely-low-birth-weight infants who are born by cesarean delivery?Rajan Wadhawan
National Institute for Child Health and Human Development Neonatal Research Network, Bethesda, MD 02905, USA
Am J Obstet Gynecol 189:501-6. 2003..We hypothesized that infants who are born by cesarean delivery without labor will have better outcomes than those infants who are born by cesarean delivery with labor...
