Janice Douglas

Summary

Affiliation: Case Western Reserve University
Country: USA

Publications

  1. ncbi request reprint Successful blood pressure control in the African American Study of Kidney Disease and Hypertension
    Jackson T Wright
    Department of Medicine, Division of Hypertension, Case Western Reserve University, 10900 Euclid Ave, Wood Bldg, Room W 165, Cleveland, OH 44106 4982, USA
    Arch Intern Med 162:1636-43. 2002
  2. ncbi request reprint Clinical guidelines for the treatment of hypertension in African Americans
    Janice G Douglas
    Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
    Am J Cardiovasc Drugs 5:1-6. 2005
  3. ncbi request reprint Management of high blood pressure in African Americans: consensus statement of the Hypertension in African Americans Working Group of the International Society on Hypertension in Blacks
    Janice G Douglas
    Case Western Reserve University, Department of Medicine, Room W 165, 10900 Euclid Ave, Cleveland, Ohio 44106, USA
    Arch Intern Med 163:525-41. 2003
  4. ncbi request reprint Improving cardiovascular health outcomes through the use of evidence-based medicine
    Janice Douglas
    Case Western Reserve University School of Medicine, 10900 Euclid Ave, Cleveland, Ohio, USA
    Ethn Dis 15:S23-6. 2005
  5. ncbi request reprint Optimal treatment of hypertension and cardiovascular risk reduction in African Americans: treatment approaches for outpatients
    Jackson T Wright
    Clinical Hypertension Program, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH 44106 4982, USA
    J Clin Hypertens (Greenwich) 5:18-25. 2003
  6. pmc Functional diversity of AT2 receptor orthologues in closely related species
    Ying Hong Feng
    Department of Pharmacology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA
    Kidney Int 67:1731-8. 2005
  7. ncbi request reprint Cardiovascular risk reduction in hypertensive black patients with left ventricular hypertrophy: the LIFE study
    Stevo Julius
    Department of Internal Medicine, Division of Hypertension, University of Michigan Medical Center, 3918 Taubman Center, Ann Arbor, MI 48109 0356, USA
    J Am Coll Cardiol 43:1047-55. 2004
  8. ncbi request reprint Cyclic stretch-induced cPLA2 mediates ERK 1/2 signaling in rabbit proximal tubule cells
    Larry D Alexander
    Department of Medicine, Division of Nephrology and Hypertension, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland, Ohio 44106 4982, USA
    Kidney Int 65:551-63. 2004
  9. ncbi request reprint Determinants of salt sensitivity in black and white normotensive and hypertensive women
    Jackson T Wright
    Department of Medicine, Case Western Reserve University School of Medicine, University Hospitals of Cleveland, Louis Stokes Cleveland VAMC, 11100 Euclid Ave, RB and C 7311, Cleveland, OH 44106 5041, USA
    Hypertension 42:1087-92. 2003
  10. ncbi request reprint The rationale and design of the AASK cohort study
    Lawrence J Appel
    Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, Maryland, 21205, USA
    J Am Soc Nephrol 14:S166-72. 2003

Research Grants

  1. GENETICS OF SALT SENSITIVITY IN AFRICAN AMERICANS
    Janice Douglas; Fiscal Year: 2001

Detail Information

Publications16

  1. ncbi request reprint Successful blood pressure control in the African American Study of Kidney Disease and Hypertension
    Jackson T Wright
    Department of Medicine, Division of Hypertension, Case Western Reserve University, 10900 Euclid Ave, Wood Bldg, Room W 165, Cleveland, OH 44106 4982, USA
    Arch Intern Med 162:1636-43. 2002
    ..The African American Study of Kidney Disease and Hypertension (AASK) is an ongoing trial to evaluate the effect of blood pressure and choice of antihypertensive drug on the rate of decline of renal function...
  2. ncbi request reprint Clinical guidelines for the treatment of hypertension in African Americans
    Janice G Douglas
    Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
    Am J Cardiovasc Drugs 5:1-6. 2005
    ....
  3. ncbi request reprint Management of high blood pressure in African Americans: consensus statement of the Hypertension in African Americans Working Group of the International Society on Hypertension in Blacks
    Janice G Douglas
    Case Western Reserve University, Department of Medicine, Room W 165, 10900 Euclid Ave, Cleveland, Ohio 44106, USA
    Arch Intern Med 163:525-41. 2003
  4. ncbi request reprint Improving cardiovascular health outcomes through the use of evidence-based medicine
    Janice Douglas
    Case Western Reserve University School of Medicine, 10900 Euclid Ave, Cleveland, Ohio, USA
    Ethn Dis 15:S23-6. 2005
    ..However, rapidly controlling BP is critical to reduce event rates, particularly rates of stroke. Angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers consistently decrease the rate of onset of type 2 diabetes...
  5. ncbi request reprint Optimal treatment of hypertension and cardiovascular risk reduction in African Americans: treatment approaches for outpatients
    Jackson T Wright
    Clinical Hypertension Program, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH 44106 4982, USA
    J Clin Hypertens (Greenwich) 5:18-25. 2003
    ....
  6. pmc Functional diversity of AT2 receptor orthologues in closely related species
    Ying Hong Feng
    Department of Pharmacology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA
    Kidney Int 67:1731-8. 2005
    ..The present study investigated the properties of AT(2) receptors in closely related species...
  7. ncbi request reprint Cardiovascular risk reduction in hypertensive black patients with left ventricular hypertrophy: the LIFE study
    Stevo Julius
    Department of Internal Medicine, Division of Hypertension, University of Michigan Medical Center, 3918 Taubman Center, Ann Arbor, MI 48109 0356, USA
    J Am Coll Cardiol 43:1047-55. 2004
    ..We report on a subanalysis of the effects of losartan and atenolol on cardiovascular events in black patients in the Losartan Intervention For Endpoint reduction in hypertension (LIFE) study...
  8. ncbi request reprint Cyclic stretch-induced cPLA2 mediates ERK 1/2 signaling in rabbit proximal tubule cells
    Larry D Alexander
    Department of Medicine, Division of Nephrology and Hypertension, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland, Ohio 44106 4982, USA
    Kidney Int 65:551-63. 2004
    ..The rational for studying kidney epithelial cells relates to their similarity to podocytes, which undergo mechanical stretch related to changes in intraglomerular pressure...
  9. ncbi request reprint Determinants of salt sensitivity in black and white normotensive and hypertensive women
    Jackson T Wright
    Department of Medicine, Case Western Reserve University School of Medicine, University Hospitals of Cleveland, Louis Stokes Cleveland VAMC, 11100 Euclid Ave, RB and C 7311, Cleveland, OH 44106 5041, USA
    Hypertension 42:1087-92. 2003
    ..In AA but not in whites, SS is positively associated with Na+i, Ca2+i, and the ratios of Na+i to K+i and of Ca2+i to Mg2+i...
  10. ncbi request reprint The rationale and design of the AASK cohort study
    Lawrence J Appel
    Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, Maryland, 21205, USA
    J Am Soc Nephrol 14:S166-72. 2003
    ..Such results might eventually lead to new strategies that delay or prevent ESRD...
  11. ncbi request reprint Hypertension-related disease in African Americans. Factors underlying disparities in illness and its outcome
    James R Sowers
    Departments of Medicine, Biochemistry, and Cell Biology, State University of New York Health Science Center, Brooklyn College of Medicine, Brooklyn, NY 11203, USA
    Postgrad Med 112:24-6, 29-30, 33-4 passim. 2002
    ..In this article, Drs Sowers, Ferdinand, Bakris, and Douglas examine the biologic, social, and genetic factors that contribute to these health disparities, the risk for which appears in early childhood...
  12. ncbi request reprint Optimal treatment of hypertension in African Americans. Reaching and maintaining target blood pressure goals
    George L Bakris
    Departments of Preventive Medicine and Internal Medicine, Rush Hypertension Clinical Research Center, Rush Presbyterian St Luke s Medical Center, 1700 W Van Buren St, Suite 470, Chicago, IL 60612, USA
    Postgrad Med 112:73-4, 77-80, 83-4. 2002
    ..This article describes current "best practice" guidance on appropriate treatment of high blood pressure in African Americans. Two patient scenarios offer insight into clinical strategies...
  13. ncbi request reprint Barriers to blood pressure control in African Americans. Overcoming obstacles is challenging, but target goals can be attained
    Janice G Douglas
    Division of Hypertension, Department of Medicine, Case Western Reserve University School of Medicine, University Hospitals of Cleveland, Room W165, 10900 Euclid Ave, Cleveland, OH 44106 4982, USA
    Postgrad Med 112:51-2, 55, 59-62 passim. 2002
    ..When extensive efforts to achieve blood pressure control prove unattainable in the primary care setting, consultation with a hypertension specialist should be considered...
  14. pmc Gbeta gamma -independent constitutive association of Galpha s with SHP-1 and angiotensin II receptor AT2 is essential in AT2-mediated ITIM-independent activation of SHP-1
    Ying Hong Feng
    Department of Medicine, Case Western Reserve University School of Medicine, and University Hospital of Cleveland, 10900 Euclid Avenue, Cleveland, OH 44106 4982, USA
    Proc Natl Acad Sci U S A 99:12049-54. 2002
    ..The AT(2)-mediated ITIM-independent activation of SHP-1 that is distinct from the conventional mode of activation, may represent a general paradigm for activation of SHP-1/2-class tyrosine phosphatases by G protein-coupled receptors...
  15. ncbi request reprint Growth, immortalization, and differentiation potential of normal adult human proximal tubule cells
    David E Orosz
    Department of Physiology, Case Western Reserve University, Cleveland, Ohio 44106 4970, USA
    In Vitro Cell Dev Biol Anim 40:22-34. 2004
    ....
  16. pmc Oxidative signaling in renal epithelium: Critical role of cytosolic phospholipase A2 and p38(SAPK)
    Xiao lan Cui
    Department of Medicine, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland, OH 44106, USA
    Free Radic Biol Med 41:213-21. 2006
    ..In addition, p38(SAPK) provides a positive input to both growth and antiapoptotic signaling pathways induced by acute oxidative stress...

Research Grants3

  1. GENETICS OF SALT SENSITIVITY IN AFRICAN AMERICANS
    Janice Douglas; Fiscal Year: 2001
    ..To this end, careful analytic attention will be paid to the development of improved phenotype definition, as well as to the consideration of gene-gene and gene-environment interaction. ..