Research Topics
| Leona CuttlerSummaryAffiliation: Case Western Reserve University Country: USA Publications
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Detail Information
Publications
Overcoming burdens in the regulation of clinical research in children. Proceedings of a consensus conference, in historical contextRobert J Levine
The University of Chicago Pritzker School of Medicine, Chicago, IL 60637, USA
Int J Pediatr Endocrinol 2011:19. 2011..abstract:..
Growth hormone and health policyLeona Cuttler
Division of Pediatric Endocrinology, Diabetes, and Metabolism and The Center for Child Health and Policy, Rainbow Babies and Children s Hospital, Room 737, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106, USA
J Clin Endocrinol Metab 95:3149-53. 2010..In this paper, we highlight key policy issues exemplified by GH, focusing on pharmaceutical innovation, insurance coverage and pricing, and physician decisions, and we discuss their implications for endocrinology and GH use...
Patient, physician, and consumer drivers: referrals for short stature and access to specialty drugsLeona Cuttler
Department of Pediatrics, Rainbow Babies and Children s Hospital, University Hospitals Case Medical Center, Cleveland, Ohio, USA
Med Care 47:858-65. 2009..Recent expanded approval of growth hormone (GH) makes more than 585,000 US children eligible for such treatment, potentially costing over $11 billion/y...
State Children's Health Insurance Program and Pediatrics: background, policy challenges, and role in child health care deliveryLeona Cuttler
The Rainbow Center for Child Health Policy, Rainbow Babies and Children's Hospital, Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH 44106, USA
Arch Pediatr Adolesc Med 161:630-3. 2007
A national study of physician recommendations to initiate and discontinue growth hormone for short statureJ B Silvers
Weatherhead School of Management, Department of Internal Medicine, MetroHealth Medical Center, School of Medicine, Rainbow Babies and Children s Hospital, Case Western Reserve University, 11100 Euclid Ave, Room 737, Cleveland, OH 44106, USA
Pediatrics 126:468-76. 2010..We studied how physicians decided to begin GH in idiopathic short stature and how, after an initial course of treatment, they decided to continue, intensify (increase the dose), or terminate treatment...
Physician decisions to discontinue long-term medications using a two-stage framework: the case of growth hormone therapyLeona Cuttler
Department of Pediatrics, Case Western Reserve University, Cleveland, OH 44106, USA
Med Care 43:1185-93. 2005..The decision to stop growth hormone (GH) therapy is an important example because of high cost (approximately $26,000/y for a 48-kg child), complexity of treatment options, and expansion of patient populations...
Change in prevalence of chronic conditions between childhood and adolescence among extremely low-birth-weight childrenMaureen Hack
Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio, USA
JAMA 306:394-401. 2011..Extremely low-birth-weight (ELBW) children have high rates of chronic conditions during childhood. Information on their trajectory of health during adolescence is needed for health care planning...
Idiopathic short stature: decision making in growth hormone useNidhi Maheshwari
Division of Pediatric Endocrinology and Diabetes, The Center for Child Health and Policy, Department of Pediatrics, Rainbow Babies and Children s Hospital, Case Western Reserve University, 11100 Euclid Avenue, Room 737, Cleveland, OH 44106, USA
Indian J Pediatr 79:238-43. 2012..This article focuses on current ambiguities and controversies regarding GH therapy in ISS, discusses the decision-makers involved in GH therapy, and explores the factors influencing their decisions...
Growth hormone therapy and quality of life in adults and childrenDeborah J Radcliffe
Department of Pediatrics, Rainbow Babies and Childrens Hospital, Case Western Reserve University, Cleveland, Ohio 44106, USA
Pharmacoeconomics 22:499-524. 2004..These analyses are central to the development of a framework for research, decision making, and policy for GH treatment...
Treatment of childhood obesityNaveen Uli
Division of Endocrinology and Diabetes, Rainbow Babies and Childrens Hospital, Cleveland, Ohio 44106, USA
Curr Opin Endocrinol Diabetes Obes 15:37-47. 2008..To provide an overview of treatments for childhood obesity, highlighting recent advances and recommendations...
Idiopathic short statureRose A Gubitosi-Klug
Department of Pediatrics, Rainbow Babies and Children's Hospital, Case Western Reserve University, Cleveland, OH 44106, USA
Endocrinol Metab Clin North Am 34:565-80, viii. 2005....
Long-term budesonide or nedocromil treatment, once discontinued, does not alter the course of mild to moderate asthma in children and adolescentsRobert C Strunk
Department of Pediatrics, Washington University School of Medicine, St Louis Children s Hospital, St Louis, MO 63110, USA
J Pediatr 154:682-7. 2009..To determine whether long-term, continuous use of inhaled anti-inflammatory medications affects asthma outcomes in children with mild to moderate asthma after use is discontinued...
Parent involvement is associated with early success in obesity treatmentLeslie J Heinberg
Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio, USA
Clin Pediatr (Phila) 49:457-65. 2010..The study examined the influence of parent involvement and family factors on body mass index (BMI) change in a pediatric obesity treatment program...
Growth of very low birth weight infants to age 20 yearsMaureen Hack
Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio, USA
Pediatrics 112:e30-8. 2003..As part of a longitudinal study of VLBW infants, we sought to examine gender-specific changes in growth from birth to 20 years old and to identify the correlates of growth attainment at 20 years old...
The overweight adolescent: clinical and ethical issues in intensive treatments for pediatric obesityLeona Cuttler
Division of Pediatric Endocrinology and Metabolism, Rainbow Babies and Children's Hospital, 11100 Euclid Avenue, Cleveland, OH 44106, USA
J Pediatr 146:559-64. 2005
Effect of long-term corticosteroid use on bone mineral density in children: a prospective longitudinal assessment in the childhood Asthma Management Program (CAMP) studyH William Kelly
Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131 0001, USA
Pediatrics 122:e53-61. 2008..Thus, we assessed the effects of multiple short courses of oral corticosteroids and long-term inhaled corticosteroids on bone mineral accretion over a period of years...
Effect of growth hormone therapy on height in children with idiopathic short stature: a meta-analysisBeth S Finkelstein
Department of Pediatrics, Rainbow Babies and Children's Hospital, Room 737, Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH 44106, USA
Arch Pediatr Adolesc Med 156:230-40. 2002..Use of GH for idiopathic short stature in clinical practice will depend on its efficacy in promoting growth and the value of this effect to families, physicians, and third-party payers...
Growth hormone treatment for idiopathic short stature: implications for practice and policyLeona Cuttler
Arch Pediatr Adolesc Med 158:108-10. 2004
