Research Topics
Species | Cynthia M BeallSummaryAffiliation: Case Western Reserve University Country: USA Publications
| Collaborators |
Detail Information
Publications
Nitric oxide in adaptation to altitudeCynthia M Beall
Department of Anthropology, Case Western Reserve University, Cleveland, OH 44106, USA
Free Radic Biol Med 52:1123-34. 2012..Gains in understanding will require integrating appropriate methods and measurement techniques with indicators of adaptive function under hypoxic stress...
Detecting natural selection in high-altitude human populationsCynthia M Beall
Case Western Reserve University, Department of Anthropology, Cleveland, OH 44106 7125, United States
Respir Physiol Neurobiol 158:161-71. 2007..New approaches use candidate gene and genomic analyses. Conclusive evidence about population genetic differences and associations with phenotypes remains to be discovered...
Two routes to functional adaptation: Tibetan and Andean high-altitude nativesCynthia M Beall
Department of Anthropology, Case Western Reserve University, Cleveland, OH 44106, USA
Proc Natl Acad Sci U S A 104:8655-60. 2007..Identifying the genetic bases of these traits is crucial to discovering the steps along the Tibetan and Andean routes to functional adaptation...
Nitric oxide and cardiopulmonary hemodynamics in Tibetan highlandersBrian D Hoit
Department of Medicine, University Hospitals of Cleveland and Case Western Reserve University, Cleveland, OH 44106 5038, USA
J Appl Physiol 99:1796-801. 2005....
Elevated pulmonary artery pressure among Amhara highlanders in EthiopiaBrian D Hoit
Department of Medicine, Case Western Reserve University, Cleveland, OH 44106 7125, USA
Am J Hum Biol 23:168-76. 2011..The objective of this study was to identify the consequences of lifelong hypoxia exposure for the pulmonary vasculature among Amhara high-altitude natives from Ethiopia...
High-altitude adaptationsCynthia M Beall
Department of Anthropology, Case Western Reserve University, Cleveland, OH 44106-7125, USA
Lancet 362:s14-5. 2003
Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlandersCynthia M Beall
Department of Anthropology, Case Western Reserve University, Cleveland, OH 44106 7125, USA
Proc Natl Acad Sci U S A 107:11459-64. 2010..Whichever of these explanations is correct, the evidence for genetic selection at the EPAS1 locus from the GWADS study is supported by the replicated studies associating function with the allelic variants...
Higher offspring survival among Tibetan women with high oxygen saturation genotypes residing at 4,000 mCynthia M Beall
Department of Anthropology, Case Western Reserve University, 238 Mather Memorial Building, 11220 Bellflower Road, Cleveland, OH 44106, USA
Proc Natl Acad Sci U S A 101:14300-4. 2004....
An Ethiopian pattern of human adaptation to high-altitude hypoxiaCynthia M Beall
Department of Anthropology, Case Western Reserve University, Cleveland, OH 44106, USA
Proc Natl Acad Sci U S A 99:17215-8. 2002..Thus, Ethiopian highlanders maintain venous hemoglobin concentrations and arterial oxygen saturation within the ranges of sea level populations, despite the unavoidable, universal decrease in the ambient oxygen tension at high altitude...
Exhaled nitric oxide decreases upon acute exposure to high-altitude hypoxiaDaniel E Brown
Department of Anthropology, University of Hawaii at Hilo, Hilo, HI 96720
Am J Hum Biol 18:196-202. 2006..There was no significant association between the level of NO exhaled and the number of self-reported symptoms of AMS during this brief exposure...
