Research Topics
| Paul M BarrSummaryAffiliation: Case Western Reserve University Country: USA Publications
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Detail Information
Publications
The role of bortezomib in the treatment of lymphomaPaul Barr
Department of Hematology, Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio 44106, USA
Cancer Invest 25:766-75. 2007..In this review, we will detail the clinical results and ongoing trials utilizing bortezomib in Hodgkin's and non-Hodgkin's lymphoma...
Phase I trial of fludarabine, bortezomib and rituximab for relapsed and refractory indolent and mantle cell non-Hodgkin lymphomaPaul M Barr
Department of Medicine, University Hospitals Case Medical Center, Cleveland, OH 44106, USA
Br J Haematol 147:89-96. 2009..Cumulative myelosuppression and neuropathy was observed. The combination of fludarabine, bortezomib, and rituximab appears to be an active regimen with manageable toxicity for relapsed NHL...
Non-Hodgkin's lymphoma in the elderlyPaolo F Caimi
Department of Medicine, Case Comprehensive Cancer Center, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio 44106, USA
Drugs Aging 27:211-38. 2010..Highly selected individuals up to age 70 years may attain long-term survival benefit from autoHCT, although transplant-related mortality is higher than in younger patients...
Spontaneous autologous graft-versus-host disease in plasma cell myeloma autograft recipients: flow cytometric analysis of hematopoietic progenitor cell graftsHillard M Lazarus
Department of Medicine, Division of Hematology Oncology, Case Comprehensive Cancer Center, University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA
Biol Blood Marrow Transplant 17:970-8. 2011..Prompt recognition of this condition and protracted treatment with nonabsorbable or systemic corticosteroids or the combination may lead to resolution...
Targeting Bcl-2 based on the interaction of its BH4 domain with the inositol 1,4,5-trisphosphate receptorYi Ping Rong
Department of Medicine, Comprehensive Cancer Center and University Hospital of Cleveland, Case Western Reserve University, Cleveland, OH 44106, USA
Biochim Biophys Acta 1793:971-8. 2009..In addition, we speculate on how the BH4 domain of Bcl-2 can be targeted therapeutically not only for diseases associated with apoptosis resistance, but also for diseases associated with accelerated cell death...
Correlation between ZAP-70, phospho-ZAP-70, and phospho-Syk expression in leukemic cells from patients with CLLDavid Kaplan
Department of Pathology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio 44106, USA
Cytometry B Clin Cytom 78:115-22. 2010....
Phase II study of bryostatin 1 and vincristine for aggressive non-Hodgkin lymphoma relapsing after an autologous stem cell transplantPaul M Barr
Department of Medicine, Case Comprehensive Cancer Center, University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA
Am J Hematol 84:484-7. 2009..Future investigations of agents targeting the protein kinase C pathway may benefit from early response assessment using flow cytometry to evaluate T-cell apoptosis...
Follicular non-Hodgkin lymphoma: long-term results of stem-cell transplantationPaul M Barr
Department of Medicine, Case Comprehensive Cancer Center, University Hospitals Case Medical Center, Cleveland, OH 44106, USA
Curr Opin Oncol 20:502-8. 2008..Hematopoietic stem-cell transplantation is an effective treatment option for follicular lymphoma. This review summarizes recent updates of the literature focusing on the available long-term follow-up of high-dose therapeutic approaches...
