Joshua J Augustine

Summary

Affiliation: Case Western Reserve University
Country: USA

Publications

  1. ncbi request reprint A randomized controlled trial comparing intermittent with continuous dialysis in patients with ARF
    Joshua J Augustine
    Department of Nephrology and Hypertension, Case Western University Hospitals, Cleveland, OH 44106, USA
    Am J Kidney Dis 44:1000-7. 2004
  2. ncbi request reprint Comparative effects of sirolimus and mycophenolate mofetil on erythropoiesis in kidney transplant patients
    Joshua J Augustine
    Department of Nephrology, Case Western University Hospitals, Cleveland, OH, USA
    Am J Transplant 4:2001-6. 2004
  3. ncbi request reprint Pre-transplant IFN-gamma ELISPOTs are associated with post-transplant renal function in African American renal transplant recipients
    Joshua J Augustine
    Division of Nephrology, University Hospitals of Cleveland, Cleveland, Ohio, USA
    Am J Transplant 5:1971-5. 2005
  4. ncbi request reprint Improved renal function after conversion from tacrolimus/sirolimus to tacrolimus/mycophenolate mofetil in kidney transplant recipients
    Joshua J Augustine
    Division of Nephrology, University Hospitals of Cleveland, OH 44106, USA
    Transplantation 81:1004-9. 2006
  5. pmc Effects of cellular sensitization and donor age on acute rejection and graft function after deceased-donor kidney transplantation
    Donald E Hricik
    Division of Nephrology, Department of Medicine, University Hospitals Case Medical Center, Cleveland, OH 44106, USA
    Transplantation 95:1254-8. 2013
  6. ncbi request reprint Long-term graft outcomes after steroid withdrawal in African American kidney transplant recipients receiving sirolimus and tacrolimus
    Donald E Hricik
    Department of Medicine, Case Western Reserve University, Cleveland, OH, USA
    Transplantation 83:277-81. 2007
  7. ncbi request reprint Fever, infection, and rejection after kidney transplant failure
    Kenneth J Woodside
    1 Division of Transplant Surgery, Department of Surgery, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio 2 Division of Nephrology, Department of Internal Medicine, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio 3 Address correspondence to Joshua J Augustine, M D, Division of Nephrology, Department of Internal Medicine, University Hospitals Case Medical Center, 11100 Euclid Avenue, LKS 5048, Cleveland, OH 44106
    Transplantation 97:648-53. 2014
  8. ncbi request reprint Hemodialysis vintage, black ethnicity, and pretransplantation antidonor cellular immunity in kidney transplant recipients
    Joshua J Augustine
    Division of Nephrology and Hypertension, Case Medical Center, 11100 Euclid Avenue, 1817 Mather, Cleveland, OH 44106, USA
    J Am Soc Nephrol 18:1602-6. 2007
  9. doi request reprint Independent of nephrectomy, weaning immunosuppression leads to late sensitization after kidney transplant failure
    Joshua J Augustine
    Department of Medicine, University Hospitals Case Medical Center, Cleveland, OH 44106, USA
    Transplantation 94:738-43. 2012
  10. ncbi request reprint Preferential benefit of antibody induction therapy in kidney recipients with high pretransplant frequencies of donor-reactive interferon-gamma enzyme-linked immunosorbent spots
    Joshua J Augustine
    Division of Nephrology and Hypertension, University Hospitals Case Medical Center, Cleveland, OH, USA
    Transplantation 86:529-34. 2008

Detail Information

Publications21

  1. ncbi request reprint A randomized controlled trial comparing intermittent with continuous dialysis in patients with ARF
    Joshua J Augustine
    Department of Nephrology and Hypertension, Case Western University Hospitals, Cleveland, OH 44106, USA
    Am J Kidney Dis 44:1000-7. 2004
    ..We sought to analyze differences in survival between modalities in a study that compared continuous venovenous hemodialysis (CVVHD) with IHD...
  2. ncbi request reprint Comparative effects of sirolimus and mycophenolate mofetil on erythropoiesis in kidney transplant patients
    Joshua J Augustine
    Department of Nephrology, Case Western University Hospitals, Cleveland, OH, USA
    Am J Transplant 4:2001-6. 2004
    ..028). Our results indicate that, compared to treatment with MMF, treatment of kidney or kidney-pancreas recipients with sirolimus is associated with a higher prevalence of anemia, lower hemoglobin levels and lower incidence of PTE...
  3. ncbi request reprint Pre-transplant IFN-gamma ELISPOTs are associated with post-transplant renal function in African American renal transplant recipients
    Joshua J Augustine
    Division of Nephrology, University Hospitals of Cleveland, Cleveland, Ohio, USA
    Am J Transplant 5:1971-5. 2005
    ....
  4. ncbi request reprint Improved renal function after conversion from tacrolimus/sirolimus to tacrolimus/mycophenolate mofetil in kidney transplant recipients
    Joshua J Augustine
    Division of Nephrology, University Hospitals of Cleveland, OH 44106, USA
    Transplantation 81:1004-9. 2006
    ..There is limited data on the potential nephrotoxicity of sirolimus (SRL) and tacrolimus (TAC) in combination...
  5. pmc Effects of cellular sensitization and donor age on acute rejection and graft function after deceased-donor kidney transplantation
    Donald E Hricik
    Division of Nephrology, Department of Medicine, University Hospitals Case Medical Center, Cleveland, OH 44106, USA
    Transplantation 95:1254-8. 2013
    ..Pretransplantation cellular sensitization may interact with advanced donor age to increase the risk of immune injury after deceased-donor kidney transplantation...
  6. ncbi request reprint Long-term graft outcomes after steroid withdrawal in African American kidney transplant recipients receiving sirolimus and tacrolimus
    Donald E Hricik
    Department of Medicine, Case Western Reserve University, Cleveland, OH, USA
    Transplantation 83:277-81. 2007
    ..We now report the long-term outcomes of patients subjected to this protocol...
  7. ncbi request reprint Fever, infection, and rejection after kidney transplant failure
    Kenneth J Woodside
    1 Division of Transplant Surgery, Department of Surgery, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio 2 Division of Nephrology, Department of Internal Medicine, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio 3 Address correspondence to Joshua J Augustine, M D, Division of Nephrology, Department of Internal Medicine, University Hospitals Case Medical Center, 11100 Euclid Avenue, LKS 5048, Cleveland, OH 44106
    Transplantation 97:648-53. 2014
    ....
  8. ncbi request reprint Hemodialysis vintage, black ethnicity, and pretransplantation antidonor cellular immunity in kidney transplant recipients
    Joshua J Augustine
    Division of Nephrology and Hypertension, Case Medical Center, 11100 Euclid Avenue, 1817 Mather, Cleveland, OH 44106, USA
    J Am Soc Nephrol 18:1602-6. 2007
    ..Longer HD vintage may also explain the increased T cell alloreactivity that previously was observed in black kidney recipients...
  9. doi request reprint Independent of nephrectomy, weaning immunosuppression leads to late sensitization after kidney transplant failure
    Joshua J Augustine
    Department of Medicine, University Hospitals Case Medical Center, Cleveland, OH 44106, USA
    Transplantation 94:738-43. 2012
    ..We hypothesized that nephrectomy for cause is a consequence of weaning immunosuppression and that weaning leads to sensitization even in the absence of nephrectomy...
  10. ncbi request reprint Preferential benefit of antibody induction therapy in kidney recipients with high pretransplant frequencies of donor-reactive interferon-gamma enzyme-linked immunosorbent spots
    Joshua J Augustine
    Division of Nephrology and Hypertension, University Hospitals Case Medical Center, Cleveland, OH, USA
    Transplantation 86:529-34. 2008
    ....
  11. ncbi request reprint Reduction in erythropoietin resistance after conversion from sirolimus to enteric coated mycophenolate sodium
    Joshua J Augustine
    Division of Nephrology and Hypertension, Department of Medicine, University Hospitals Case Medical Center, Cleveland, OH, USA
    Transplantation 86:548-53. 2008
    ..After observing the need for high dose exogenous erythropoietin dosage in some patients on SRL, we hypothesized that SRL therapy may influence anemia by inducing a state of erythropoietin resistance...
  12. ncbi request reprint Pretransplant cellular alloimmunity as assessed by a panel of reactive T cells assay correlates with acute renal graft rejection
    Emilio D Poggio
    Department of Nephrology and Hypertension, Transplant Center, Cleveland Clinic, Cleveland, OH 44195, USA
    Transplantation 83:847-52. 2007
    ....
  13. ncbi request reprint Steroid sparing in kidney transplantation: changing paradigms, improving outcomes, and remaining questions
    Joshua J Augustine
    Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA
    Clin J Am Soc Nephrol 1:1080-9. 2006
    ..Although the outcomes of kidney transplant recipients who are treated with steroid-free immunosuppression are improving steadily, there still is room for concern in recommending this strategy as a standard of practice...
  14. pmc Effects of influenza immunization on humoral and cellular alloreactivity in humans
    Lara Danziger-Isakov
    Department of Pediatrics, Cleveland Clinic, Cleveland, OH, USA
    Transplantation 89:838-44. 2010
    ..To test whether vaccination impacts human alloimmunity, we analyzed humoral and cellular immune reactivity in subjects undergoing influenza vaccination...
  15. ncbi request reprint Use of sirolimus in solid organ transplantation
    Joshua J Augustine
    The Department of Medicine and the Transplantation Service, Case Western Reserve University, and University Hospitals of Cleveland, Cleveland, Ohio, USA
    Drugs 67:369-91. 2007
    ..As is true for all immunosuppressive drugs available for treatment of solid organ transplant recipients, the efficacy of the drug must be balanced against its considerable adverse effects...
  16. ncbi request reprint Differences in proteinuria and graft function in de novo sirolimus-based vs. calcineurin inhibitor-based immunosuppression in live donor kidney transplantation
    Brian R Stephany
    Department of Nephrology and Hypertension, Cleveland Clinic Foundation, OH 44195, USA
    Transplantation 82:368-74. 2006
    ..Calcineurin inhibitor(CNI)-free protocols using sirolimus (SRL) in kidney transplantation have proven effective, although reports have linked SRL to proteinuria. We sought to investigate this link and its impact on graft function...
  17. doi request reprint Induction antibody therapy in kidney transplantation
    Aparna Padiyar
    Department of Medicine, University Hospitals Case Medical Center and Case Western Reserve University, Cleveland, OH 44106, USA
    Am J Kidney Dis 54:935-44. 2009
    ..Some, but not all, antibodies are associated with increased risk of posttransplantation lymphoproliferative disease and other malignancies...
  18. doi request reprint T-cell immune monitoring by the ELISPOT assay for interferon gamma
    Joshua J Augustine
    Division of Nephrology and Hypertension, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio 44116, USA
    Clin Chim Acta 413:1359-63. 2012
    ..Additional work is needed to validate the assay in larger multicenter clinical trials...
  19. ncbi request reprint Minimization of immunosuppression in kidney transplantation
    Joshua J Augustine
    Department of Medicine, University Hospitals Case Medical Center and Case Western Reserve University, Cleveland, Ohio 44106, USA
    Curr Opin Nephrol Hypertens 16:535-41. 2007
    ..This article focuses on outcomes of these strategies described in recently published trials...
  20. doi request reprint Alloreactive T cells and 'the persistence of memory'
    Emilio D Poggio
    Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio, USA
    Kidney Int 84:1074-6. 2013
    ....
  21. ncbi request reprint Anemia after kidney transplantation: time for action
    Joshua J Augustine
    J Am Soc Nephrol 17:2962-3. 2006