Yubo Sun

Summary

Affiliation: Carolinas Medical Center
Country: USA

Publications

  1. pmc Biological activities of phosphocitrate: a potential meniscal protective agent
    Yubo Sun
    Department of Orthopedic Research Biology, Cannon Research, Carolinas Medical Center, Charlotte, NC 28232, USA
    Biomed Res Int 2013:726581. 2013
  2. pmc Phosphocitrate is potentially a disease-modifying drug for noncrystal-associated osteoarthritis
    Yubo Sun
    Department of Orthopedic Surgery, Carolinas Medical Center, P O Box 32861, Charlotte, NC 28232, USA
    Biomed Res Int 2013:326267. 2013
  3. pmc Calcium deposition in osteoarthritic meniscus and meniscal cell culture
    Yubo Sun
    Department of Orthopaedic Surgery, Carolinas Medical Center, PO Box 32861, Charlotte, NC 28232, USA
    Arthritis Res Ther 12:R56. 2010
  4. pmc Analysis of meniscal degeneration and meniscal gene expression
    Yubo Sun
    Department of Orthopaedic Surgery, Carolinas Medical Center, Charlotte, NC 28232, USA
    BMC Musculoskelet Disord 11:19. 2010
  5. doi request reprint Micromass culture of human anulus cells: morphology and extracellular matrix production
    Helen E Gruber
    Department of Orthopaedic Surgery, Orthopaedic Research Biology, Carolinas Medical Center, Charlotte, NC 32861, USA
    Spine (Phila Pa 1976) 35:1033-8. 2010
  6. pmc Telomerase transduced osteoarthritis fibroblast-like synoviocytes display a distinct gene expression profile
    Yubo Sun
    Department of Orthopaedic Surgery, Biology Division, Cannon Research 304, Carolinas Medical Center, Charlotte, NC 28232, USA
    J Rheumatol 36:141-55. 2009
  7. pmc Asporin, a susceptibility gene in osteoarthritis, is expressed at higher levels in the more degenerate human intervertebral disc
    Helen E Gruber
    Department of Orthopedic Surgery, Carolinas Medical Center, Charlotte, NC 28232, USA
    Arthritis Res Ther 11:R47. 2009
  8. ncbi request reprint Longterm culture of telomerase-transduced rheumatoid arthritis fibroblast-like synoviocytes display a distinct gene expression pattern
    Yubo Sun
    Department of Orthopaedic Surgery, Carolinas Medical Center, Charlotte, North Carolina, USA
    J Rheumatol 34:1959-70. 2007
  9. pmc Histological examination of collagen and proteoglycan changes in osteoarthritic menisci
    Yubo Sun
    Department of Orthopedic Surgery, Carolinas Medical Center, PO Box 32861, Charlotte, NC 28232, USA
    Open Rheumatol J 6:24-32. 2012
  10. pmc Three-dimensional culture of human meniscal cells: extracellular matrix and proteoglycan production
    Helen E Gruber
    Department of Orthopaedic Surgery, Carolinas Medical Center, Charlotte, NC, USA
    BMC Biotechnol 8:54. 2008

Detail Information

Publications12

  1. pmc Biological activities of phosphocitrate: a potential meniscal protective agent
    Yubo Sun
    Department of Orthopedic Research Biology, Cannon Research, Carolinas Medical Center, Charlotte, NC 28232, USA
    Biomed Res Int 2013:726581. 2013
    ..These findings indicate that PC is potentially a meniscal-protective agent and a disease-modifying drug for arthritis associated with severe meniscal degeneration. ..
  2. pmc Phosphocitrate is potentially a disease-modifying drug for noncrystal-associated osteoarthritis
    Yubo Sun
    Department of Orthopedic Surgery, Carolinas Medical Center, P O Box 32861, Charlotte, NC 28232, USA
    Biomed Res Int 2013:326267. 2013
    ..These findings suggest that PC is not only a promising disease-modifying drug for crystal-associated OA but also for noncrystal-associated OA...
  3. pmc Calcium deposition in osteoarthritic meniscus and meniscal cell culture
    Yubo Sun
    Department of Orthopaedic Surgery, Carolinas Medical Center, PO Box 32861, Charlotte, NC 28232, USA
    Arthritis Res Ther 12:R56. 2010
    ..This study sought to examine calcium deposition in OA meniscus and to investigate OA meniscal cell-mediated calcium deposition. The hypothesis was that OA meniscal cells may play a role in pathological meniscal calcification...
  4. pmc Analysis of meniscal degeneration and meniscal gene expression
    Yubo Sun
    Department of Orthopaedic Surgery, Carolinas Medical Center, Charlotte, NC 28232, USA
    BMC Musculoskelet Disord 11:19. 2010
    ..This study sought: 1) to determine the prevalence of meniscal degeneration in OA patients, and 2) to examine gene expression in OA meniscal cells compared to normal meniscal cells...
  5. doi request reprint Micromass culture of human anulus cells: morphology and extracellular matrix production
    Helen E Gruber
    Department of Orthopaedic Surgery, Orthopaedic Research Biology, Carolinas Medical Center, Charlotte, NC 32861, USA
    Spine (Phila Pa 1976) 35:1033-8. 2010
    ..Micromass culture was assessed as a cell culture microenvironment for anulus cells from the human intervertebral disc...
  6. pmc Telomerase transduced osteoarthritis fibroblast-like synoviocytes display a distinct gene expression profile
    Yubo Sun
    Department of Orthopaedic Surgery, Biology Division, Cannon Research 304, Carolinas Medical Center, Charlotte, NC 28232, USA
    J Rheumatol 36:141-55. 2009
    ....
  7. pmc Asporin, a susceptibility gene in osteoarthritis, is expressed at higher levels in the more degenerate human intervertebral disc
    Helen E Gruber
    Department of Orthopedic Surgery, Carolinas Medical Center, Charlotte, NC 28232, USA
    Arthritis Res Ther 11:R47. 2009
    ..There have been no studies, however, of this gene's normal immunohistochemical localization within the human intervertebral disc, or of expression levels in Caucasian individuals with disc degeneration...
  8. ncbi request reprint Longterm culture of telomerase-transduced rheumatoid arthritis fibroblast-like synoviocytes display a distinct gene expression pattern
    Yubo Sun
    Department of Orthopaedic Surgery, Carolinas Medical Center, Charlotte, North Carolina, USA
    J Rheumatol 34:1959-70. 2007
    ....
  9. pmc Histological examination of collagen and proteoglycan changes in osteoarthritic menisci
    Yubo Sun
    Department of Orthopedic Surgery, Carolinas Medical Center, PO Box 32861, Charlotte, NC 28232, USA
    Open Rheumatol J 6:24-32. 2012
    ..These findings are not only important for a better understanding of the disease process but also important for the development of novel structure-modifying drugs for OA therapy...
  10. pmc Three-dimensional culture of human meniscal cells: extracellular matrix and proteoglycan production
    Helen E Gruber
    Department of Orthopaedic Surgery, Carolinas Medical Center, Charlotte, NC, USA
    BMC Biotechnol 8:54. 2008
    ....
  11. doi request reprint Meniscal calcification, pathogenesis and implications
    Yubo Sun
    Department of Orthopedic Surgery, Carolinas Medical Center, Charlotte, North Carolina 28232, USA
    Curr Opin Rheumatol 24:152-7. 2012
    ..The purpose of this review is to discuss recent advances in the understanding of the nature of meniscal calcification and its relationships with meniscal degeneration and cartilage lesions in osteoarthritis...
  12. ncbi request reprint Crystal deposits in the human intervertebral disc: implications for disc degeneration
    Helen E Gruber
    Department of Orthopaedic Surgery, Orthopedic Research Biology, Carolinas Medical Center, Charlotte, NC 28232, USA
    Spine J 7:444-50. 2007
    ..In articular cartilage matrix, crystal deposits are associated with altered extracellular matrix (ECM) and cell phenotypic features, but crystal deposition in the human intervertebral disc has received much less attention...