Research Topics
Species | Yubo SunSummaryAffiliation: Carolinas Medical Center Country: USA Publications
| Collaborators |
Detail Information
Publications
Analysis of meniscal degeneration and meniscal gene expressionYubo Sun
Department of Orthopaedic Surgery, Carolinas Medical Center, Charlotte, NC 28232, USA
BMC Musculoskelet Disord 11:19. 2010..This study sought: 1) to determine the prevalence of meniscal degeneration in OA patients, and 2) to examine gene expression in OA meniscal cells compared to normal meniscal cells...
Calcium deposition in osteoarthritic meniscus and meniscal cell cultureYubo Sun
Department of Orthopaedic Surgery, Carolinas Medical Center, PO Box 32861, Charlotte, NC 28232, USA
Arthritis Res Ther 12:R56. 2010..This study sought to examine calcium deposition in OA meniscus and to investigate OA meniscal cell-mediated calcium deposition. The hypothesis was that OA meniscal cells may play a role in pathological meniscal calcification...
Micromass culture of human anulus cells: morphology and extracellular matrix productionHelen E Gruber
Department of Orthopaedic Surgery, Orthopaedic Research Biology, Carolinas Medical Center, Charlotte, NC 32861, USA
Spine (Phila Pa 1976) 35:1033-8. 2010..Micromass culture was assessed as a cell culture microenvironment for anulus cells from the human intervertebral disc...
Telomerase transduced osteoarthritis fibroblast-like synoviocytes display a distinct gene expression profileYubo Sun
Department of Orthopaedic Surgery, Biology Division, Cannon Research 304, Carolinas Medical Center, Charlotte, NC 28232, USA
J Rheumatol 36:141-55. 2009....
Asporin, a susceptibility gene in osteoarthritis, is expressed at higher levels in the more degenerate human intervertebral discHelen E Gruber
Department of Orthopedic Surgery, Carolinas Medical Center, Charlotte, NC 28232, USA
Arthritis Res Ther 11:R47. 2009..There have been no studies, however, of this gene's normal immunohistochemical localization within the human intervertebral disc, or of expression levels in Caucasian individuals with disc degeneration...
Histological examination of collagen and proteoglycan changes in osteoarthritic menisciYubo Sun
Department of Orthopedic Surgery, Carolinas Medical Center, PO Box 32861, Charlotte, NC 28232, USA
Open Rheumatol J 6:24-32. 2012..These findings are not only important for a better understanding of the disease process but also important for the development of novel structure-modifying drugs for OA therapy...
Three-dimensional culture of human meniscal cells: extracellular matrix and proteoglycan productionHelen E Gruber
Department of Orthopaedic Surgery, Carolinas Medical Center, Charlotte, NC, USA
BMC Biotechnol 8:54. 2008....
Phosphocitrate is potentially a disease-modifying drug for noncrystal-associated osteoarthritisYubo Sun
Department of Orthopedic Surgery, Carolinas Medical Center, P O Box 32861, Charlotte, NC 28232, USA
Biomed Res Int 2013:326267. 2013..These findings suggest that PC is not only a promising disease-modifying drug for crystal-associated OA but also for noncrystal-associated OA...
Longterm culture of telomerase-transduced rheumatoid arthritis fibroblast-like synoviocytes display a distinct gene expression patternYubo Sun
Department of Orthopaedic Surgery, Carolinas Medical Center, Charlotte, North Carolina, USA
J Rheumatol 34:1959-70. 2007....
Meniscal calcification, pathogenesis and implicationsYubo Sun
Department of Orthopedic Surgery, Carolinas Medical Center, Charlotte, North Carolina 28232, USA
Curr Opin Rheumatol 24:152-7. 2012..The purpose of this review is to discuss recent advances in the understanding of the nature of meniscal calcification and its relationships with meniscal degeneration and cartilage lesions in osteoarthritis...
Crystal deposits in the human intervertebral disc: implications for disc degenerationHelen E Gruber
Department of Orthopaedic Surgery, Orthopedic Research Biology, Carolinas Medical Center, Charlotte, NC 28232, USA
Spine J 7:444-50. 2007..In articular cartilage matrix, crystal deposits are associated with altered extracellular matrix (ECM) and cell phenotypic features, but crystal deposition in the human intervertebral disc has received much less attention...
