P B Lockhart

Summary

Affiliation: Carolinas Medical Center
Country: USA

Publications

  1. ncbi Decision-making on the use of antimicrobial prophylaxis for dental procedures: a survey of infectious disease consultants and review
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC, 28232, USA
    Clin Infect Dis 34:1621-6. 2002
  2. ncbi Acceptance among and impact on dental practitioners and patients of American Heart Association recommendations for antibiotic prophylaxis
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, 1000 Blythe Blvd, P O Box 32861, Charlotte, N C 28232 2861, USA
    J Am Dent Assoc 144:1030-5. 2013
  3. doi Drug cost implications for antibiotic prophylaxis for dental procedures
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC 28232 2861, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol 115:345-53. 2013
  4. doi Concomitant surgical treatment of dental and valvular heart diseases
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC 28232 2861, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 107:71-6. 2009
  5. pmc Bacteremia associated with toothbrushing and dental extraction
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, PO Box 32861, Charlotte, NC 28232 2861, USA
    Circulation 117:3118-25. 2008
  6. ncbi The evidence base for the efficacy of antibiotic prophylaxis in dental practice
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC 28232 2861, USA
    J Am Dent Assoc 138:458-74; quiz 534-5, 437. 2007
  7. pmc Poor oral hygiene as a risk factor for infective endocarditis-related bacteremia
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, P O Box 32861, Charlotte, NC 28232 2861, USA
    J Am Dent Assoc 140:1238-44. 2009
  8. ncbi Randomized controlled trial of pilocarpine hydrochloride for the moderation of oral mucositis during autologous blood stem cell transplantation
    P B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC, USA
    Bone Marrow Transplant 35:713-20. 2005
  9. ncbi Impact of amoxicillin prophylaxis on the incidence, nature, and duration of bacteremia in children after intubation and dental procedures
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, 1000 Blythe Blvd, PO Box 32861, Charlotte, NC 28232 2861, USA
    Circulation 109:2878-84. 2004
  10. ncbi Dental management considerations for the patient with an acquired coagulopathy. Part 1: Coagulopathies from systemic disease
    P B Lockhart
    Glasgow Dental Hospital and School, 387 Sauchiehall Street, University of Glasgow, Glasgow G2 3JZ, Scotland, UK
    Br Dent J 195:439-45. 2003

Research Grants

  1. Bacteremia from Dental Extraction vs. Oral Hygiene
    Peter Lockhart; Fiscal Year: 2002
  2. Bacteremia from Dental Extraction vs. Oral Hygiene
    Peter Lockhart; Fiscal Year: 2003
  3. Bacteremia from Dental Extraction vs. Oral Hygiene
    Peter Lockhart; Fiscal Year: 2004
  4. World Workshop in Oral Medicine IV
    Peter Lockhart; Fiscal Year: 2005

Collaborators

Detail Information

Publications45

  1. ncbi Decision-making on the use of antimicrobial prophylaxis for dental procedures: a survey of infectious disease consultants and review
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC, 28232, USA
    Clin Infect Dis 34:1621-6. 2002
    ..These differences underscore the need for definitive studies to delineate appropriate candidates for antimicrobial prophylaxis in dental practice...
  2. ncbi Acceptance among and impact on dental practitioners and patients of American Heart Association recommendations for antibiotic prophylaxis
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, 1000 Blythe Blvd, P O Box 32861, Charlotte, N C 28232 2861, USA
    J Am Dent Assoc 144:1030-5. 2013
    ..The purpose of the authors' study was to determine the acceptance of these changes among and the impact of the changes on dentists and their patients...
  3. doi Drug cost implications for antibiotic prophylaxis for dental procedures
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC 28232 2861, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol 115:345-53. 2013
    ..To determine the potential economic impact from the practice of antibiotic prophylaxis for dental procedures...
  4. doi Concomitant surgical treatment of dental and valvular heart diseases
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC 28232 2861, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 107:71-6. 2009
    ..Invasive dental procedures are often indicated before cardiac valve surgery. The purpose of this case-control study was to determine the risks and benefits of concomitant dental and thoracic surgery...
  5. pmc Bacteremia associated with toothbrushing and dental extraction
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, PO Box 32861, Charlotte, NC 28232 2861, USA
    Circulation 117:3118-25. 2008
    ....
  6. ncbi The evidence base for the efficacy of antibiotic prophylaxis in dental practice
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC 28232 2861, USA
    J Am Dent Assoc 138:458-74; quiz 534-5, 437. 2007
    ..The authors conducted a qualitative, systematic review to determine the level of evidence for this practice and whether antibiotic prophylaxis prevents distant site infections in these patients...
  7. pmc Poor oral hygiene as a risk factor for infective endocarditis-related bacteremia
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, P O Box 32861, Charlotte, NC 28232 2861, USA
    J Am Dent Assoc 140:1238-44. 2009
    ..The authors conducted a study to determine if poor oral hygiene or dental disease are risk factors for developing bacteremia after toothbrushing or single-tooth extraction...
  8. ncbi Randomized controlled trial of pilocarpine hydrochloride for the moderation of oral mucositis during autologous blood stem cell transplantation
    P B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC, USA
    Bone Marrow Transplant 35:713-20. 2005
    ..Pilocarpine has no benefit for the moderation of the incidence, severity, or duration of mucositis in patients receiving autologous blood stem cell transplantation...
  9. ncbi Impact of amoxicillin prophylaxis on the incidence, nature, and duration of bacteremia in children after intubation and dental procedures
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, 1000 Blythe Blvd, PO Box 32861, Charlotte, NC 28232 2861, USA
    Circulation 109:2878-84. 2004
    ....
  10. ncbi Dental management considerations for the patient with an acquired coagulopathy. Part 1: Coagulopathies from systemic disease
    P B Lockhart
    Glasgow Dental Hospital and School, 387 Sauchiehall Street, University of Glasgow, Glasgow G2 3JZ, Scotland, UK
    Br Dent J 195:439-45. 2003
  11. ncbi Dental management considerations for the patient with an acquired coagulopathy. Part 2: Coagulopathies from drugs
    P B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, North Carolina 28232, USA
    Br Dent J 195:495-501. 2003
    ..The vast majority of these patients can be managed in the community setting without risk and without alteration of anticoagulant drug regimes...
  12. doi Dental postoperative bleeding complications in patients with suspected and documented liver disease
    C H Hong
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC, USA
    Oral Dis 18:661-6. 2012
    ....
  13. ncbi Aspirin use and post-operative bleeding from dental extractions
    M T Brennan
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC 28232, USA
    J Dent Res 87:740-4. 2008
    ..Whole-blood aggregation results were significantly different between the aspirin and placebo groups. These findings suggest that there is no indication to discontinue aspirin for persons requiring single-tooth extraction...
  14. ncbi Prevalence of oral lesions of autoimmune etiology in patients with primary Sjogren's syndrome
    K Likar-Manookin
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC, USA
    Oral Dis 19:598-603. 2013
    ..The primary objective of this study was to determine the prevalence of oral lesions of autoimmune etiology (OLAIE) in a cohort of patients with primary Sjögren's syndrome (pSS)...
  15. doi The oral mucosa as a therapeutic target for xerostomia
    W R Thelin
    Parion Sciences, Durham, NC, USA
    Oral Dis 14:683-9. 2008
    ..This review discusses the current understanding of oral fluid balance and how these processes may be manipulated to provide relief for those suffering from dry mouth...
  16. ncbi Incidence of acute oral sequelae in pediatric patients undergoing chemotherapy
    C H Hong
    Pediatric Dentistry, Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC, USA
    Pediatr Dent 31:420-5. 2009
    ..The purpose of this literature review was to assess the incidence of acute oral sequelae in children receiving cytotoxic therapy...
  17. ncbi Statistical analysis used in "A prospective placebo-controlled double-blind trial of antibiotic prophylaxis in intraoral bone grafting procedures: a pliot study"
    Michael T Brennan
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 97:664; author reply 664-5. 2004
  18. ncbi Dental treatment planning and management in the patient who has cancer
    Michael T Brennan
    Department of Oral Medicine, Carolinas Medical Center, PO Box 32861, Charlotte, NC 28232, USA
    Dent Clin North Am 52:19-37, vii. 2008
    ....
  19. ncbi Oral health needs and barriers to dental care in hospitalized children
    Martine Nicopoulos
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC, USA
    Spec Care Dentist 27:206-11. 2007
    ..A high prevalance of unmet oral health needs and soft tissue abnormalities was identified in a hospitalized pediatric population. Children with chronic medical conditions were more likely to experience barriers to obtaining dental care...
  20. ncbi Prevention of infective endocarditis: guidelines from the American Heart Association: a guideline from the American Heart Association Rheumatic Fever, Endocarditis and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Cou
    Walter Wilson
    J Am Dent Assoc 139:3S-24S. 2008
    ..The purpose of this statement is to update the recommendations by the American Heart Association (AHA) for the prevention of infective endocarditis, which were last published in 1997...
  21. pmc Diverse and novel oral bacterial species in blood following dental procedures
    Farah K Bahrani-Mougeot
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, North Carolina 28203, USA
    J Clin Microbiol 46:2129-32. 2008
    ..Of interest, 48 of the isolates represented 19 novel species of Prevotella, Fusobacterium, Streptococcus, Actinomyces, Capnocytophaga, Selenomonas, and Veillonella...
  22. doi Identification of oral bacteria in blood cultures by conventional versus molecular methods
    Farah K Bahrani-Mougeot
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC 28232, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 105:720-4. 2008
    ..The purpose of this study was to compare two different methods of identifying oral bacteria from blood samples after dental extractions...
  23. ncbi Treatment of xerostomia: a systematic review of therapeutic trials
    Michael T Brennan
    Department of Oral Medicine, Carolinas Medical Center, Post Office Box 3280, Charlotte, NC 28232, USA
    Dent Clin North Am 46:847-56. 2002
    ..Minimizing bias in clinical studies will allow for easier interpretation and comparisons of different studies. Better clinical trial design is vital to provide maximal confidence in the efficacy of xerostomia interventions...
  24. ncbi Relationship between bleeding time test and postextraction bleeding in a healthy control population
    Michael T Brennan
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC 28232, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 94:439-43. 2002
    ..We sought to determine whether cutaneous bleeding time (BT) is related to bleeding outcome measures after a single tooth extraction...
  25. ncbi Cevimeline for the treatment of xerostomia in patients with Sjögren syndrome: a randomized trial
    Rose S Fife
    Department of Medicine, Indiana University School of Medicine, 535 Barnhill Dr, Room 150, Indianapolis, IN 46202, USA
    Arch Intern Med 162:1293-300. 2002
    ..We evaluated the safety and efficacy of cevimeline in the treatment of xerostomia in patients with Sjögren syndrome...
  26. ncbi Salivary dysfunction associated with systemic diseases: systematic review and clinical management recommendations
    Inger von Bültzingslöwen
    Department of Oral Medicine, Sahlgrenska Academy, Goteborg University, Goteborg, Sweden
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103:S57.e1-15. 2007
    ..The objective of this study was to identify systemic diseases associated with hyposalivation and xerostomia and develop evidence-based management recommendations for hyposalivation/xerostomia...
  27. ncbi Radiation-induced trismus in head and neck cancer patients
    M Louise Kent
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC 28203, USA
    Support Care Cancer 16:305-9. 2008
    ..In addition, we assessed if trismus was associated with quality of life deficits and radiation toxicity...
  28. ncbi Prevention of infective endocarditis: guidelines from the American Heart Association: a guideline from the American Heart Association Rheumatic Fever, Endocarditis and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Cou
    Walter Wilson
    Mayo Clinic, Rochester, MN, USA
    J Am Dent Assoc 138:739-45, 747-60. 2007
    ..The purpose of this statement is to update the recommendations by the American Heart Association (AHA) for the prevention of infective endocarditis, which were last published in 1997...
  29. ncbi Efficacy of penicillin for dental pain without overt infection
    Michael S Runyon
    Department of Emergency Medicine, Carolinas Medical Center, P O Box 32861, Charlotte, NC 28232 2861, USA
    Acad Emerg Med 11:1268-71. 2004
    ..The authors sought to test the hypothesis that penicillin is not necessary or beneficial in the treatment of undifferentiated dental pain without overt infection...
  30. ncbi Odontogenic signs and symptoms as predictors of odontogenic infection: a clinical trial
    Michael T Brennan
    Oral Medicine Residency, Carolinas Medical Center, Department of Oral Medicine, 1000 Blythe Blvd, MEB 409, Charlotte, NC 28232, USA
    J Am Dent Assoc 137:62-6. 2006
    ..The authors conducted a study to determine if odontogenic signs and symptoms in the emergency department predicted the development of overt odontogenic infection at a follow-up dental visit...
  31. ncbi Relationship between mucositis and changes in oral microflora during cancer chemotherapy
    Joel J Napenas
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103:48-59. 2007
    ..More detailed studies are required to understand the relationship between chemotherapy, alterations in the nature and magnitude of the oral microflora, and the presence of mucositis...
  32. ncbi The impact of oral disease and nonsurgical treatment on bacteremia in children
    Michael T Brennan
    Department of Oral Medicine, Carolinas Medical Center, P O Box 32861, Charlotte, NC 28232, USA
    J Am Dent Assoc 138:80-5. 2007
    ..The authors examine the role of dental disease and nonsurgical dental procedures in the incidence and duration of bacteremia in children...
  33. ncbi Utility of an international normalized ratio testing device in a hospital-based dental practice
    Michael T Brennan
    Department of Oral Medicine, Carolinas Medical Center, P O Box 32861, Charlotte, N C 28232, USA
    J Am Dent Assoc 139:697-703. 2008
    ..The authors aimed to evaluate the utility of an in-office international normalized ratio (INR) testing device in identifying patients with INR test values considered out of the normal range for dental procedures...
  34. ncbi Modified Child-Pugh score as a marker for postoperative bleeding from invasive dental procedures
    Manuel A Valerin
    Carolina Medical Center, Charlotte, NC, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 104:56-60. 2007
    ..The objective of this study was to determine if the modified Child-Pugh score (MCP) is associated with peri- and postoperative bleeding complications from invasive dental procedures in patients with advanced liver disease...
  35. ncbi Prevention of premature discontinuation of dual antiplatelet therapy in patients with coronary artery stents: a science advisory from the American Heart Association, American College of Cardiology, Society for Cardiovascular Angiography and Interventions,
    Cindy L Grines
    J Am Coll Cardiol 49:734-9. 2007
    ..It also recommends postponing elective surgery for 1 year, and if surgery cannot be deferred, considering the continuation of aspirin during the perioperative period in high-risk patients with drug-eluting stents...
  36. ncbi Relationship between oral bacteria and hemodialysis access infection
    Galib Shariff
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 98:418-22. 2004
    ..The purpose of this study was to determine the extent to which oral bacteria are associated with vascular access site infections in a group of HD patients...
  37. ncbi Prevention of premature discontinuation of dual antiplatelet therapy in patients with coronary artery stents: a science advisory from the American Heart Association, American College of Cardiology, Society for Cardiovascular Angiography and Interventions,
    Cindy L Grines
    William Beaumont Hospital, Royal Oak, Michigan, USA
    J Am Dent Assoc 138:652-5. 2007
    ..It also recommends postponing elective surgery for one year, and if surgery cannot be deferred, considering the continuation of aspirin during the perioperative period in high-risk patients with drug-eluting stents...
  38. ncbi The role of oral microbial colonization in ventilator-associated pneumonia
    Michael T Brennan
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 98:665-72. 2004
    ..We need a deeper understanding of the pathophysiology of VAP in order to reduce the morbidity, mortality, and cost from this common complication in ICU medicine and surgery...
  39. ncbi Prevention of infective endocarditis: guidelines from the American Heart Association: a guideline from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Co
    Walter Wilson
    Mayo Clinic, USA
    Circulation 116:1736-54. 2007
    ..The purpose of this statement is to update the recommendations by the American Heart Association (AHA) for the prevention of infective endocarditis that were last published in 1997...
  40. ncbi Guidelines for prevention of infective endocarditis: an explanation of the changes
    Peter B Lockhart
    Departmentof Oral Medicine, Carolinas Medical Center, Charlotte, NC, USA
    J Am Dent Assoc 139:2S. 2008
  41. ncbi World Workshop on Oral Medicine IV: Process and methodology for systematic review and developing management recommendations. Reference manual for management recommendations writing committees
    Lorena Baccaglini
    University of Florida, Gainesville, Florida, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103:S3.e1-19. 2007
  42. ncbi Prevention of premature discontinuation of dual antiplatelet therapy in patients with coronary artery stents: a science advisory from the American Heart Association, American College of Cardiology, Society for Cardiovascular Angiography and Interventions,
    Cindy L Grines
    William Beaumont Hospital
    Circulation 115:813-8. 2007
    ..It also recommends postponing elective surgery for 1 year, and if surgery cannot be deferred, considering the continuation of aspirin during the perioperative period in high-risk patients with drug-eluting stents...
  43. pmc Molecular analysis of oral and respiratory bacterial species associated with ventilator-associated pneumonia
    Farah K Bahrani-Mougeot
    Department of Oral Medicine, Carolinas Medical Center, P O Box 32861, Charlotte, NC 28232, USA
    J Clin Microbiol 45:1588-93. 2007
    ..Furthermore, it is clear that the diversity of bacterial pathogens for VAP is far more complex than the current literature suggests...
  44. ncbi Prevention of premature discontinuation of dual antiplatelet therapy in patients with coronary artery stents: a science advisory from the American Heart Association, American College of Cardiology, Society for Cardiovascular Angiography and Interventions,
    Cindy L Grines
    Catheter Cardiovasc Interv 69:334-40. 2007
    ..It also recommends postponing elective surgery for 1 year, and if surgery cannot be deferred, considering the continuation of aspirin during the perioperative period in high-risk patients with drug-eluting stents...
  45. ncbi Management of oral epithelial dysplasia: a review
    Michael Brennan
    Carolinas Medical Center, Charlotte, NC, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103:S19.e1-12. 2007
    ..Because of the lack of randomized controlled trials that have shown effectiveness in the prevention of malignant transformation, no recommendations can be provided for specific surgical interventions of dysplastic oral lesions either...

Research Grants4

  1. Bacteremia from Dental Extraction vs. Oral Hygiene
    Peter Lockhart; Fiscal Year: 2002
    ..Additionally, we will have unique and critical data for the development of both future research and evidence-based guidelines concerning antibiotic prophylaxis for individuals currently felt to be at risk for DSI. ..
  2. Bacteremia from Dental Extraction vs. Oral Hygiene
    Peter Lockhart; Fiscal Year: 2003
    ..Additionally, we will have unique and critical data for the development of both future research and evidence-based guidelines concerning antibiotic prophylaxis for individuals currently felt to be at risk for DSI. ..
  3. Bacteremia from Dental Extraction vs. Oral Hygiene
    Peter Lockhart; Fiscal Year: 2004
    ..Additionally, we will have unique and critical data for the development of both future research and evidence-based guidelines concerning antibiotic prophylaxis for individuals currently felt to be at risk for DSI. ..
  4. World Workshop in Oral Medicine IV
    Peter Lockhart; Fiscal Year: 2005
    ..The proceedings will be published as evidence-based recommendations for best clinical practice in Oral Medicine as well as providing suggestions for future basic science and clinical research. ..