Michael T Brennan

Summary

Affiliation: Carolinas Medical Center
Country: USA

Publications

  1. ncbi request reprint Focal sialadenitis in patients with early synovitis
    M T Brennan
    Clinical Research Core, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA
    Clin Exp Rheumatol 19:444-6. 2001
  2. ncbi request reprint Risk factors for positive minor salivary gland biopsy findings in Sjögren's syndrome and dry mouth patients
    Michael T Brennan
    National Institute of Dental and Craniofacial Research NIDCR, NIH, Bethesda, Maryland, USA
    Arthritis Rheum 47:189-95. 2002
  3. ncbi request reprint Pilot clinical trial of dehydroepiandrosterone (DHEA) versus placebo for Sjögren's syndrome
    Stanley R Pillemer
    National Institute of Dental and Craniofacial Research, Bethesda, Maryland 28092, USA
    Arthritis Rheum 51:601-4. 2004
  4. ncbi request reprint Etanercept in Sjögren's syndrome: a twelve-week randomized, double-blind, placebo-controlled pilot clinical trial
    Vidya Sankar
    National Institutes of Health, Bethesda, Maryland, USA
    Arthritis Rheum 50:2240-5. 2004
  5. ncbi request reprint Sex steroid hormones in primary Sjögren's syndrome
    Michael T Brennan
    Gene Therapy and Therapeutics Branch GTTB, National Institute of Dental and Craniofacial Research NIDCR, National Institutes of Health, Bethesda, Maryland, USA
    J Rheumatol 30:1267-71. 2003
  6. ncbi request reprint Elevated blood pressure is not related to saliva flow in patients with Sjögren's syndrome
    Vidya Sankar
    Gene Therapy and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 94:179-83. 2002
  7. pmc Poor oral hygiene as a risk factor for infective endocarditis-related bacteremia
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, P O Box 32861, Charlotte, NC 28232 2861, USA
    J Am Dent Assoc 140:1238-44. 2009
  8. ncbi request reprint The evidence base for the efficacy of antibiotic prophylaxis in dental practice
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC 28232 2861, USA
    J Am Dent Assoc 138:458-74; quiz 534-5, 437. 2007
  9. doi request reprint Molecular methodology to assess the impact of cancer chemotherapy on the oral bacterial flora: a pilot study
    Joel J Napenas
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC 28232, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109:554-60. 2010
  10. ncbi request reprint Radiation-induced trismus in head and neck cancer patients
    M Louise Kent
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC 28203, USA
    Support Care Cancer 16:305-9. 2008

Detail Information

Publications38

  1. ncbi request reprint Focal sialadenitis in patients with early synovitis
    M T Brennan
    Clinical Research Core, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA
    Clin Exp Rheumatol 19:444-6. 2001
    ..To investigate the frequency of sialadenitis on lip biopsy in patients with synovitis of recent onset (ES), and see how sialadenitis relates to clinical and laborator findings of ES...
  2. ncbi request reprint Risk factors for positive minor salivary gland biopsy findings in Sjögren's syndrome and dry mouth patients
    Michael T Brennan
    National Institute of Dental and Craniofacial Research NIDCR, NIH, Bethesda, Maryland, USA
    Arthritis Rheum 47:189-95. 2002
    ..To investigate risk factors for positive minor salivary gland biopsy results in Sjögren's syndrome (SS) and dry mouth patients...
  3. ncbi request reprint Pilot clinical trial of dehydroepiandrosterone (DHEA) versus placebo for Sjögren's syndrome
    Stanley R Pillemer
    National Institute of Dental and Craniofacial Research, Bethesda, Maryland 28092, USA
    Arthritis Rheum 51:601-4. 2004
    ..To screen for potential efficacy and assess feasibility and safety of dehydroepiandrosterone (DHEA) as a treatment for Sjögren's syndrome (SS)...
  4. ncbi request reprint Etanercept in Sjögren's syndrome: a twelve-week randomized, double-blind, placebo-controlled pilot clinical trial
    Vidya Sankar
    National Institutes of Health, Bethesda, Maryland, USA
    Arthritis Rheum 50:2240-5. 2004
    ..To assess the safety and potential efficacy of etanercept in the treatment of Sjögren's syndrome (SS)...
  5. ncbi request reprint Sex steroid hormones in primary Sjögren's syndrome
    Michael T Brennan
    Gene Therapy and Therapeutics Branch GTTB, National Institute of Dental and Craniofacial Research NIDCR, National Institutes of Health, Bethesda, Maryland, USA
    J Rheumatol 30:1267-71. 2003
    ..To investigate the relationships between concentrations of sex hormones and measures of disease activity in patients with primary Sjögren's Syndrome (pSS)...
  6. ncbi request reprint Elevated blood pressure is not related to saliva flow in patients with Sjögren's syndrome
    Vidya Sankar
    Gene Therapy and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 94:179-83. 2002
    ....
  7. pmc Poor oral hygiene as a risk factor for infective endocarditis-related bacteremia
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, P O Box 32861, Charlotte, NC 28232 2861, USA
    J Am Dent Assoc 140:1238-44. 2009
    ..The authors conducted a study to determine if poor oral hygiene or dental disease are risk factors for developing bacteremia after toothbrushing or single-tooth extraction...
  8. ncbi request reprint The evidence base for the efficacy of antibiotic prophylaxis in dental practice
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC 28232 2861, USA
    J Am Dent Assoc 138:458-74; quiz 534-5, 437. 2007
    ..The authors conducted a qualitative, systematic review to determine the level of evidence for this practice and whether antibiotic prophylaxis prevents distant site infections in these patients...
  9. doi request reprint Molecular methodology to assess the impact of cancer chemotherapy on the oral bacterial flora: a pilot study
    Joel J Napenas
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC 28232, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109:554-60. 2010
    ..This pilot study determined the profile of the oral bacterial flora in an outpatient cancer population before and after chemotherapy using molecular techniques...
  10. ncbi request reprint Radiation-induced trismus in head and neck cancer patients
    M Louise Kent
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC 28203, USA
    Support Care Cancer 16:305-9. 2008
    ..In addition, we assessed if trismus was associated with quality of life deficits and radiation toxicity...
  11. pmc Bacteremia associated with toothbrushing and dental extraction
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, PO Box 32861, Charlotte, NC 28232 2861, USA
    Circulation 117:3118-25. 2008
    ....
  12. doi request reprint Concomitant surgical treatment of dental and valvular heart diseases
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC 28232 2861, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 107:71-6. 2009
    ..Invasive dental procedures are often indicated before cardiac valve surgery. The purpose of this case-control study was to determine the risks and benefits of concomitant dental and thoracic surgery...
  13. doi request reprint Frequency of bleeding following invasive dental procedures in patients on low-molecular-weight heparin therapy
    Catherine H L Hong
    Pediatric Dentistry, Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC 28203, USA
    J Oral Maxillofac Surg 68:975-9. 2010
    ..The purpose of this study was to determine the frequency of bleeding complications after invasive dental procedures in patients on low-molecular-weight heparin (LMWH) therapy...
  14. ncbi request reprint The frequency of bleeding complications after invasive dental treatment in patients receiving single and dual antiplatelet therapy
    Joel J Napenas
    General Practice Residency, Department of Oral Medicine, Carolinas Medical Center, P O Box 32861, Charlotte, N C 28232, USA
    J Am Dent Assoc 140:690-5. 2009
    ..The authors conducted a study to examine the frequency of bleeding complications after invasive dental procedures in patients taking antiplatelet medications...
  15. pmc A systematic review of dental disease in patients undergoing cancer therapy
    Catherine H L Hong
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC 28232, USA
    Support Care Cancer 18:1007-21. 2010
    ....
  16. ncbi request reprint Impact of amoxicillin prophylaxis on the incidence, nature, and duration of bacteremia in children after intubation and dental procedures
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, 1000 Blythe Blvd, PO Box 32861, Charlotte, NC 28232 2861, USA
    Circulation 109:2878-84. 2004
    ....
  17. ncbi request reprint Treatment of xerostomia: a systematic review of therapeutic trials
    Michael T Brennan
    Department of Oral Medicine, Carolinas Medical Center, Post Office Box 3280, Charlotte, NC 28232, USA
    Dent Clin North Am 46:847-56. 2002
    ..Minimizing bias in clinical studies will allow for easier interpretation and comparisons of different studies. Better clinical trial design is vital to provide maximal confidence in the efficacy of xerostomia interventions...
  18. ncbi request reprint Relationship between bleeding time test and postextraction bleeding in a healthy control population
    Michael T Brennan
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC 28232, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 94:439-43. 2002
    ..We sought to determine whether cutaneous bleeding time (BT) is related to bleeding outcome measures after a single tooth extraction...
  19. ncbi request reprint Decision-making on the use of antimicrobial prophylaxis for dental procedures: a survey of infectious disease consultants and review
    Peter B Lockhart
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC, 28232, USA
    Clin Infect Dis 34:1621-6. 2002
    ..These differences underscore the need for definitive studies to delineate appropriate candidates for antimicrobial prophylaxis in dental practice...
  20. ncbi request reprint Efficacy of penicillin for dental pain without overt infection
    Michael S Runyon
    Department of Emergency Medicine, Carolinas Medical Center, P O Box 32861, Charlotte, NC 28232 2861, USA
    Acad Emerg Med 11:1268-71. 2004
    ..The authors sought to test the hypothesis that penicillin is not necessary or beneficial in the treatment of undifferentiated dental pain without overt infection...
  21. ncbi request reprint A retrospective investigation of advanced periodontal disease as a risk factor for septicemia in hematopoietic stem cell and bone marrow transplant recipients
    Sunday O Akintoye
    Clinical Research Core and Craniofacial and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research NIDCR, National Institute of Health NIH, Bethesda, MD, 20892 4320 USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 94:581-8. 2002
    ..The primary aim of the present study was to determine impact of chronic periodontitis, as measured by radiographic alveolar bone loss, on septicemia and transplant mortality...
  22. ncbi request reprint The impact of oral disease and nonsurgical treatment on bacteremia in children
    Michael T Brennan
    Department of Oral Medicine, Carolinas Medical Center, P O Box 32861, Charlotte, NC 28232, USA
    J Am Dent Assoc 138:80-5. 2007
    ..The authors examine the role of dental disease and nonsurgical dental procedures in the incidence and duration of bacteremia in children...
  23. ncbi request reprint Utility of an international normalized ratio testing device in a hospital-based dental practice
    Michael T Brennan
    Department of Oral Medicine, Carolinas Medical Center, P O Box 32861, Charlotte, N C 28232, USA
    J Am Dent Assoc 139:697-703. 2008
    ..The authors aimed to evaluate the utility of an in-office international normalized ratio (INR) testing device in identifying patients with INR test values considered out of the normal range for dental procedures...
  24. ncbi request reprint Dental treatment planning and management in the patient who has cancer
    Michael T Brennan
    Department of Oral Medicine, Carolinas Medical Center, PO Box 32861, Charlotte, NC 28232, USA
    Dent Clin North Am 52:19-37, vii. 2008
    ....
  25. ncbi request reprint Oral health needs and barriers to dental care in hospitalized children
    Martine Nicopoulos
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC, USA
    Spec Care Dentist 27:206-11. 2007
    ..A high prevalance of unmet oral health needs and soft tissue abnormalities was identified in a hospitalized pediatric population. Children with chronic medical conditions were more likely to experience barriers to obtaining dental care...
  26. ncbi request reprint Statistical analysis used in "A prospective placebo-controlled double-blind trial of antibiotic prophylaxis in intraoral bone grafting procedures: a pliot study"
    Michael T Brennan
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 97:664; author reply 664-5. 2004
  27. ncbi request reprint Odontogenic signs and symptoms as predictors of odontogenic infection: a clinical trial
    Michael T Brennan
    Oral Medicine Residency, Carolinas Medical Center, Department of Oral Medicine, 1000 Blythe Blvd, MEB 409, Charlotte, NC 28232, USA
    J Am Dent Assoc 137:62-6. 2006
    ..The authors conducted a study to determine if odontogenic signs and symptoms in the emergency department predicted the development of overt odontogenic infection at a follow-up dental visit...
  28. ncbi request reprint Salivary dysfunction associated with systemic diseases: systematic review and clinical management recommendations
    Inger von Bültzingslöwen
    Department of Oral Medicine, Sahlgrenska Academy, Goteborg University, Goteborg, Sweden
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103:S57.e1-15. 2007
    ..The objective of this study was to identify systemic diseases associated with hyposalivation and xerostomia and develop evidence-based management recommendations for hyposalivation/xerostomia...
  29. ncbi request reprint Alimentary mucositis: putting the guidelines into practice
    Michael T Brennan
    Carolinas Medical Center, Charlotte, NC, USA
    Support Care Cancer 14:573-9. 2006
    ..The Mucositis Study Group of the Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology completed an evidence-based review of the literature for the management of alimentary mucositis...
  30. ncbi request reprint Growth factors and cytokines in the prevention and treatment of oral and gastrointestinal mucositis
    Inger von Bültzingslöwen
    Department of Oral Medicine, Sahlgrenska Academy, Goteborg University, P O Box 450, 405 30, Goteborg, Sweden
    Support Care Cancer 14:519-27. 2006
    ..The aim of these evidence-based scientific reviews was to critically evaluate the literature and create evidence-based guidelines for the use of growth factors and cytokines in the prevention or treatment of CT- and RT-induced mucositis...
  31. ncbi request reprint Modified Child-Pugh score as a marker for postoperative bleeding from invasive dental procedures
    Manuel A Valerin
    Carolina Medical Center, Charlotte, NC, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 104:56-60. 2007
    ..The objective of this study was to determine if the modified Child-Pugh score (MCP) is associated with peri- and postoperative bleeding complications from invasive dental procedures in patients with advanced liver disease...
  32. ncbi request reprint The role of oral microbial colonization in ventilator-associated pneumonia
    Michael T Brennan
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 98:665-72. 2004
    ..We need a deeper understanding of the pathophysiology of VAP in order to reduce the morbidity, mortality, and cost from this common complication in ICU medicine and surgery...
  33. ncbi request reprint Prominent adverse effects of thalidomide in primary Sjögren's syndrome
    Stanley R Pillemer
    Arthritis Rheum 51:505-6. 2004
  34. ncbi request reprint Aspirin and bleeding in dentistry: an update and recommendations
    Michael T Brennan
    Oral Medicine Residency Director, Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 104:316-23. 2007
    ....
  35. ncbi request reprint Relationship between oral bacteria and hemodialysis access infection
    Galib Shariff
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 98:418-22. 2004
    ..The purpose of this study was to determine the extent to which oral bacteria are associated with vascular access site infections in a group of HD patients...
  36. ncbi request reprint World Workshop on Oral Medicine IV: Process and methodology for systematic review and developing management recommendations. Reference manual for management recommendations writing committees
    Lorena Baccaglini
    University of Florida, Gainesville, Florida, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103:S3.e1-19. 2007
  37. pmc Molecular analysis of oral and respiratory bacterial species associated with ventilator-associated pneumonia
    Farah K Bahrani-Mougeot
    Department of Oral Medicine, Carolinas Medical Center, P O Box 32861, Charlotte, NC 28232, USA
    J Clin Microbiol 45:1588-93. 2007
    ..Furthermore, it is clear that the diversity of bacterial pathogens for VAP is far more complex than the current literature suggests...
  38. ncbi request reprint Relationship between mucositis and changes in oral microflora during cancer chemotherapy
    Joel J Napenas
    Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103:48-59. 2007
    ..More detailed studies are required to understand the relationship between chemotherapy, alterations in the nature and magnitude of the oral microflora, and the presence of mucositis...