Research Topics
| MARCEL A JUSTSummaryAffiliation: Carnegie Mellon University Country: USA Publications
Research Grants
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Detail Information
Publications
Autism as a neural systems disorder: a theory of frontal-posterior underconnectivityMarcel Adam Just
Center for Cognitive Brain Imaging, Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213, USA
Neurosci Biobehav Rev 36:1292-313. 2012..The theory provides a unified account of how a neural dysfunction can produce a neural systems disorder and a psychological disorder with the widespread and diverse symptoms of autism...
Cortical activation and synchronization during sentence comprehension in high-functioning autism: evidence of underconnectivityMarcel Adam Just
Carnegie Mellon University, Center for Cognitive Brain Imaging, Department of Psychology, Pittsburgh, PA 15213, USA
Brain 127:1811-21. 2004..The article presents a theoretical account of the findings, related to neurobiological foundations of underconnectivity in autism...- Imagery in sentence comprehension: an fMRI studyMarcel Adam Just
Center for Cognitive Brain Imaging, Department of Psychology, Carnegie Mellon University, 15213, Pittsburgh, PA, USA
Neuroimage 21:112-24. 2004..In particular, the left intraparietal sulcus area appears to be centrally involved in processing the visual imagery that a sentence can evoke, while activating in synchrony with some core language processing regions... - The organization of thinking: what functional brain imaging reveals about the neuroarchitecture of complex cognitionMarcel Adam Just
Department of Psychology, Center for Cognitive Brain Imaging, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
Cogn Affect Behav Neurosci 7:153-91. 2007..Finally, we compare 4CAPS with other proposed neuroarchitectures... - A decrease in brain activation associated with driving when listening to someone speakMarcel Adam Just
Center for Cognitive Brain Imaging, Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
Brain Res 1205:70-80. 2008..The findings show that language comprehension performed concurrently with driving draws mental resources away from the driving and produces deterioration in driving performance, even when it does not require holding or dialing a phone... - A neurosemantic theory of concrete noun representation based on the underlying brain codesMarcel Adam Just
Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA
PLoS ONE 5:e8622. 2010..The methods, findings, and theory constitute a new approach of using brain activity for understanding how object concepts are represented in the mind... - Atypical frontal-posterior synchronization of Theory of Mind regions in autism during mental state attributionRajesh K Kana
Carnegie Mellon University, Pittsburgh, PA, USA
Soc Neurosci 4:135-52. 2009..The results together provide new evidence for the biological basis of atypical processing of ToM in autism, implicating the underconnectivity between frontal regions and more posterior areas... - Modifying the brain activation of poor readers during sentence comprehension with extended remedial instruction: a longitudinal study of neuroplasticityAnn Meyler
Center for Cognitive Brain Imaging, Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213, United States
Neuropsychologia 46:2580-92. 2008..Areas of overactivation were also found among poor readers in the medial frontal cortex, possibly indicating a more effortful and attentive guided reading strategy... - The synchronization of the human cortical working memory networkSharlene D Newman
Center for Cognitive Brain Imaging, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
Neuroimage 15:810-22. 2002..The coordination of cortical area responses reveals how the various cortical regions synchronize and collaborate in order to accomplish a given cognitive function... - Functional connectivity in an fMRI working memory task in high-functioning autismHideya Koshino
Center for Cognitive Brain Imaging, Carnegie Mellon University, Pittsburgh, PA 15213, USA
Neuroimage 24:810-21. 2005..The temporal profile of the activity in the prefrontal regions was more correlated with the left parietal regions for the control group, whereas it was more correlated with the right parietal regions for the autism group... - Interactions between the dorsal and the ventral pathways in mental rotation: an fMRI studyHideya Koshino
Carnegie Mellon University, Pittsburgh, Pennsylvania, USA
Cogn Affect Behav Neurosci 5:54-66. 2005..The results indicate that both the dorsal and the ventral pathways show interactive effects of object and spatial processing, and they suggest that multiple regions interact to perform mental rotation... - Inhibitory control in high-functioning autism: decreased activation and underconnectivity in inhibition networksRajesh K Kana
Center for Cognitive Brain Imaging, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
Biol Psychiatry 62:198-206. 2007..There has been only one published functional magnetic resonance imaging (fMRI) study so far on inhibition in autism, which found greater activation in participants with autism than control participants... - An fMRI study of bilingual sentence comprehension and workloadMihoko Hasegawa
Center for Cognitive Brain Imaging, Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213, USA
Neuroimage 15:647-60. 2002..These results suggest that a shared network of cortical regions supports the processing of both a first and a second language, such that the second language requires more computation and activity from the network... - Neural basis of dyslexia: a comparison between dyslexic and nondyslexic children equated for reading abilityFumiko Hoeft
Department of Psychology, Stanford University, Palo Alto, California 94305 2130, USA
J Neurosci 26:10700-8. 2006.... - Altering cortical connectivity: remediation-induced changes in the white matter of poor readersTimothy A Keller
Center for Cognitive Brain Imaging, Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213, USA
Neuron 64:624-31. 2009..The results demonstrate the capability of a behavioral intervention to bring about a positive change in cortico-cortical white matter tracts... - Differential effects of syntactic and semantic processing on the subregions of Broca's areaSharlene D Newman
Department of Psychology, Carnegie Mellon University, Baker Hall 327, 5000 Forbes Ave, Pittsburgh, PA 15213, USA
Brain Res Cogn Brain Res 16:297-307. 2003..The posterior left temporal area was also involved in both types of processing... 
Predicting human brain activity associated with the meanings of nounsTom M Mitchell
Machine Learning Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA
Science 320:1191-5. 2008..Once trained, the model predicts fMRI activation for thousands of other concrete nouns in the text corpus, with highly significant accuracies over the 60 nouns for which we currently have fMRI data...- Differentiable cortical networks for inferences concerning people's intentions versus physical causalityRobert A Mason
Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
Hum Brain Mapp 32:313-29. 2011..A Protagonist monitoring and synthesis network is proposed as a more accurate account for Theory of Mind activation during narrative comprehension... - Frontal and parietal participation in problem solving in the Tower of London: fMRI and computational modeling of planning and high-level perceptionSharlene D Newman
Department of Psychology, Center for Cognitive Brain Imaging, Carnegie Mellon University, Baker Hall, 3275000 Forbes Avenue, Pittsburgh, PA 15213, USA
Neuropsychologia 41:1668-82. 2003..The multiple research approaches presented here converge on a deepening understanding of the combination of perceptual and conceptual processes in this type of visual problem solving... - Ambiguity in the brain: what brain imaging reveals about the processing of syntactically ambiguous sentencesRobert A Mason
Department of Psychology, Center for Cognitive Brain Imaging, Carnegie Mellon University, Pittsburgh, PA 15213, USA
J Exp Psychol Learn Mem Cogn 29:1319-38. 2003..The fMRI data indicate the involvement of a parallel component in syntactic parsing that might be either a selection mechanism or a construction of multiple parses... - How the brain processes causal inferences in textRobert A Mason
Center for Cognitive Brain Imaging, Carnegie Mellon University, USA
Psychol Sci 15:1-7. 2004..These two cortical networks, which are distinguishable from the classical left-hemisphere language areas, approximately correspond to the two functional relations observed in the behavioral results... - Individual differences in sentence comprehension: a functional magnetic resonance imaging investigation of syntactic and lexical processing demandsChantel S Prat
Center for Cognitive Brain Imaging, Carnegie Mellon University, Pittsburgh, PA 15213 3890, USA
J Cogn Neurosci 19:1950-63. 2007.... - Theory of Mind disruption and recruitment of the right hemisphere during narrative comprehension in autismRobert A Mason
Center for Cognitive Brain Imaging, Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213, United States
Neuropsychologia 46:269-80. 2008..Furthermore, the within-network functional connectivity in autism was correlated with the size of the anterior portion of the corpus callosum... - A developmental study of the structural integrity of white matter in autismTimothy A Keller
Center for Cognitive Brain Imaging, Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA
Neuroreport 18:23-7. 2007..These reductions may underlie the behavioral pattern observed in autism, as well as findings of reduced functional connectivity in functional magnetic resonance imaging signal between activating cortical areas... - fMRI investigation of working memory for faces in autism: visual coding and underconnectivity with frontal areasHideya Koshino
Department of Psychology, California State University, San Bernardino, CA 92407, USA
Cereb Cortex 18:289-300. 2008.... - Lexical ambiguity in sentence comprehensionRobert A Mason
Center for Cognitive Brain Imaging, Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213, USA
Brain Res 1146:115-27. 2007.... - Brain activation during sentence comprehension among good and poor readersAnn Meyler
Center for Cognitive Brain Imaging, Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213, USA
Cereb Cortex 17:2780-7. 2007..It is proposed that the functioning of the cortical network underlying reading is dependent on a combination of interacting factors, including physiological maturation, neural integrity, skill level, and the nature of the task... - Sentence comprehension in autism: thinking in pictures with decreased functional connectivityRajesh K Kana
Center for Cognitive Brain Imaging, Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213, USA
Brain 129:2484-93. 2006.... - Functional connectivity in a baseline resting-state network in autismVladimir L Cherkassky
Center for Cognitive Brain Imaging, Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
Neuroreport 17:1687-90. 2006..This functional underconnectivity was observed in the anterior-posterior connections. The results expand the theory of cortical underconnectivity in autism to the resting state of the brain... - Functional and anatomical cortical underconnectivity in autism: evidence from an FMRI study of an executive function task and corpus callosum morphometryMarcel Adam Just
Center for Cognitive Brain Imaging, Carnegie Mellon University, Pittsburgh, PA 15213, USA
Cereb Cortex 17:951-61. 2007..The results add support to a new theory of cortical underconnectivity in autism, which posits a deficit in integration of information at the neural and cognitive levels... - Imagining material versus geometric properties of objects: an fMRI studySharlene D Newman
Department of Psychology, Indiana University, 1101 E 10th Street, Bloomington, IN 47405, USA
Brain Res Cogn Brain Res 23:235-46. 2005.... - Using FMRI brain activation to identify cognitive states associated with perception of tools and dwellingsSvetlana V Shinkareva
Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA
PLoS ONE 3:e1394. 2008..These findings indicate the presence of stable, distributed, communal, and identifiable neural states corresponding to object concepts... - Brain imaging of tongue-twister sentence comprehension: twisting the tongue and the brainTimothy A Keller
Center for Cognitive Brain Imaging, Carnegie Mellon University, Pittsburgh, PA 15213, USA
Brain Lang 84:189-203. 2003.... - Brain correlates of discourse processing: an fMRI investigation of irony and conventional metaphor comprehensionZohar Eviatar
Institute of Information Processing and Decision Making, Psychology Department, University of Haifa, Haifa 31905, Israel
Neuropsychologia 44:2348-59. 2006..The findings show differential hemispheric sensitivity to these aspects of figurative language, and are relevant to models of the functional cortical architecture of language processing in connected discourse... - Prediction of children's reading skills using behavioral, functional, and structural neuroimaging measuresFumiko Hoeft
Center for Interdisciplinary Brain Sciences Research, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5795, USA
Behav Neurosci 121:602-13. 2007..Results were validated using cross-validation methods. These findings suggest that neuroimaging methods may be useful in enhancing the early identification of children at risk for poor decoding and reading skills... - Volitional control of attention and brain activation in dual task performanceSharlene D Newman
Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana 47405, USA
Hum Brain Mapp 28:109-17. 2007..This shift suggests multiple language-processing modes and may explain the underadditivity in activation observed in the current and previous studies...
Research Grants
- COGNITIVE CAPACITY & LANGUAGE COMPREHENSION--FMR STUDIESMARCEL JUST; Fiscal Year: 2001....
- fMRI Studies of Conceptual ProcessesMARCEL JUST; Fiscal Year: 2009..The research will provide tools for assessing patients with brain damage to parts of the language system and provide a basis for future therapies. ..
- COGNITIVE PROCESSING OF VISUAL INFORMATIONMARCEL JUST; Fiscal Year: 1980..The content area, methodology, and theoretical framework are all mutually compatible. They should deliver testable models and a reliable data base for the understanding of visual information processing. ..
- COGNITIVE CAPACITY AND LANGUAGE COMPREHENSIONMARCEL JUST; Fiscal Year: 1993..Third, the research develops the theoretical analysis of a psychometric instrument (the reading span test) that may prove useful for measuring age and disease-related changes in language functioning...
- The Neural Bases of he Semantic Structure of Words and ConceptsMarcel Adam Just; Fiscal Year: 2010..2009) indicates, the new approach provides a good match to the brain characteristics of several brain disorders, and it is beginning to be applied for health-related purposes in many domains. ..