Noel G Carlson

Summary

Country: USA

Publications

  1. pmc Cerebellar Purkinje cells incorporate immunoglobulins and immunotoxins in vitro: implications for human neurological disease and immunotherapeutics
    Kenneth E Hill
    Department of Neurology, University of Utah School of Medicine, 50 North Medical Drive Salt Lake City, UT 84132, USA
    J Neuroinflammation 6:31. 2009
  2. pmc Cyclooxygenase-2 expression in oligodendrocytes increases sensitivity to excitotoxic death
    Noel G Carlson
    Geriatric Research, Education Clinical Center GRECC VASLCHCS, Salt Lake City, UT, USA
    J Neuroinflammation 7:25. 2010
  3. pmc Microglial inhibition of neuroprotection by antagonists of the EP1 prostaglandin E2 receptor
    Noel G Carlson
    Geriatric Research Education and Clinical Center GRECC, VASLCHCS, Salt Lake City, UT 84148, USA
    J Neuroinflammation 6:5. 2009
  4. pmc Potential involvement of P2Y2 receptor in diuresis of postobstructive uropathy in rats
    Yue Zhang
    Nephrology Research, Department of Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah 84148, USA
    Am J Physiol Renal Physiol 298:F634-42. 2010
  5. pmc Purkinje cell death after uptake of anti-Yo antibodies in cerebellar slice cultures
    John E Greenlee
    Neurology Service, George E Wahlen Veterans Affairs Medical Center, Salt Lake City, UT 84148, USA
    J Neuropathol Exp Neurol 69:997-1007. 2010
  6. ncbi request reprint The pathologic role for COX-2 in apoptotic oligodendrocytes in virus induced demyelinating disease: implications for multiple sclerosis
    Noel G Carlson
    Geriatric Research Education and Clinical Center GRECC, Salt Lake City, UT 84148, USA
    J Neuroimmunol 174:21-31. 2006
  7. ncbi request reprint Inducible nitric oxide synthase in chronic active multiple sclerosis plaques: distribution, cellular expression and association with myelin damage
    Kenneth E Hill
    Neurovirology Research Laboratory Veterans Affairs SLCHCS, and Department of Neurology, University of Utah, Salt Lake City, USA
    J Neuroimmunol 151:171-9. 2004
  8. doi request reprint Genetic deletion of the P2Y2 receptor offers significant resistance to development of lithium-induced polyuria accompanied by alterations in PGE2 signaling
    Yue Zhang
    Nephrology Research 151M VA SLC Health Care System, 500 Foothill Dr, Salt Lake City, UT 84148, USA
    Am J Physiol Renal Physiol 302:F70-7. 2012
  9. ncbi request reprint Immunohistochemical evidence of inducible nitric oxide synthase and nitrotyrosine in a case of clinically isolated optic neuritis
    Veda L Tsoi
    Neurovirology Research Laboratory, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah 84148, USA
    J Neuroophthalmol 26:87-94. 2006
  10. doi request reprint Vitamin D as a clinical biomarker in multiple sclerosis
    Noel G Carlson
    GRECC, VA Salt Lake City Health Care System, 500 Foothill Drive, Salt Lake City, UT 84124, USA
    Expert Opin Med Diagn 7:231-42. 2013

Collaborators

Detail Information

Publications19

  1. pmc Cerebellar Purkinje cells incorporate immunoglobulins and immunotoxins in vitro: implications for human neurological disease and immunotherapeutics
    Kenneth E Hill
    Department of Neurology, University of Utah School of Medicine, 50 North Medical Drive Salt Lake City, UT 84132, USA
    J Neuroinflammation 6:31. 2009
    ..Despite the possible significance of these findings for human disease, immunoglobulin uptake by Purkinje cells has not been demonstrated in living tissue or studied systematically...
  2. pmc Cyclooxygenase-2 expression in oligodendrocytes increases sensitivity to excitotoxic death
    Noel G Carlson
    Geriatric Research, Education Clinical Center GRECC VASLCHCS, Salt Lake City, UT, USA
    J Neuroinflammation 7:25. 2010
    ..J.Neuroimmunology 2006, 149:40). This suggests that COX-2 may contribute to death of oligodendrocytes...
  3. pmc Microglial inhibition of neuroprotection by antagonists of the EP1 prostaglandin E2 receptor
    Noel G Carlson
    Geriatric Research Education and Clinical Center GRECC, VASLCHCS, Salt Lake City, UT 84148, USA
    J Neuroinflammation 6:5. 2009
    ..In this study we examined the influence of non-neuronal cells on neuroprotective properties of EP1 receptor antagonists (Ono 8711 and SC 51089)...
  4. pmc Potential involvement of P2Y2 receptor in diuresis of postobstructive uropathy in rats
    Yue Zhang
    Nephrology Research, Department of Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah 84148, USA
    Am J Physiol Renal Physiol 298:F634-42. 2010
    ..Increased mRNA expression of EP1 and EP3 receptors in POU may also help accentuate PGE2-induced signaling in the mCD...
  5. pmc Purkinje cell death after uptake of anti-Yo antibodies in cerebellar slice cultures
    John E Greenlee
    Neurology Service, George E Wahlen Veterans Affairs Medical Center, Salt Lake City, UT 84148, USA
    J Neuropathol Exp Neurol 69:997-1007. 2010
    ....
  6. ncbi request reprint The pathologic role for COX-2 in apoptotic oligodendrocytes in virus induced demyelinating disease: implications for multiple sclerosis
    Noel G Carlson
    Geriatric Research Education and Clinical Center GRECC, Salt Lake City, UT 84148, USA
    J Neuroimmunol 174:21-31. 2006
    ..The presence of the cell death marker (activated caspase 3) with COX-2 in oligodendrocytes is direct evidence linking COX-2 with cell death of oligodendrocytes in these demyelinating diseases...
  7. ncbi request reprint Inducible nitric oxide synthase in chronic active multiple sclerosis plaques: distribution, cellular expression and association with myelin damage
    Kenneth E Hill
    Neurovirology Research Laboratory Veterans Affairs SLCHCS, and Department of Neurology, University of Utah, Salt Lake City, USA
    J Neuroimmunol 151:171-9. 2004
    ..Together, these findings support a central role for iNOS in the pathogenesis of multiple sclerosis...
  8. doi request reprint Genetic deletion of the P2Y2 receptor offers significant resistance to development of lithium-induced polyuria accompanied by alterations in PGE2 signaling
    Yue Zhang
    Nephrology Research 151M VA SLC Health Care System, 500 Foothill Dr, Salt Lake City, UT 84148, USA
    Am J Physiol Renal Physiol 302:F70-7. 2012
    ....
  9. ncbi request reprint Immunohistochemical evidence of inducible nitric oxide synthase and nitrotyrosine in a case of clinically isolated optic neuritis
    Veda L Tsoi
    Neurovirology Research Laboratory, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah 84148, USA
    J Neuroophthalmol 26:87-94. 2006
    ..There is little evidence of whether the immunohistochemistry of ON resembles that of typical cerebral MS lesions...
  10. doi request reprint Vitamin D as a clinical biomarker in multiple sclerosis
    Noel G Carlson
    GRECC, VA Salt Lake City Health Care System, 500 Foothill Drive, Salt Lake City, UT 84124, USA
    Expert Opin Med Diagn 7:231-42. 2013
    ....
  11. doi request reprint Antineuronal autoantibodies in paraneoplastic cerebellar degeneration associated with adenocarcinoma of the prostate
    John E Greenlee
    Neurology Service, George E Wahlen Veterans Affairs Medical Center, Salt Lake City, UT 84148, USA
    J Neurol Sci 291:74-8. 2010
    ..Adenocarcinoma of the prostate should be considered as a possible underlying malignancy in older males with unexplained progressive cerebellar degeneration...
  12. pmc P2Y(2) receptors and water transport in the kidney
    Bellamkonda K Kishore
    Nephrology Research 151M, VA SLC Health Care System, 500 Foothill Drive, Salt Lake City, UT, 84148, USA
    Purinergic Signal 5:491-9. 2009
    ..Future studies should address the potential therapeutic benefits of modulators of P2Y(2) receptor signalling in water balance disorders, which are extremely prevalent in hospitalised patients irrespective of the underlying pathology...
  13. pmc Potential role of purinergic signaling in urinary concentration in inner medulla: insights from P2Y2 receptor gene knockout mice
    Yue Zhang
    Nephrology Research 151M VA SLC Health Care System, 500 Foothill Dr, Salt Lake City, UT 84148, USA
    Am J Physiol Renal Physiol 295:F1715-24. 2008
    ..Thus purinergic regulation may play a potential overarching role in balancing the effect of AVP on the urinary concentration mechanism...
  14. ncbi request reprint Antioxidants in multiple sclerosis: do they have a role in therapy?
    Noel G Carlson
    GRECC, VASLCHCS, Department of Neurobiology and Anatomy, University of Utah, Salt Lake City, Utah, USA
    CNS Drugs 20:433-41. 2006
    ..However, clinical trials in MS patients with more potent antioxidants, identified in animal studies, have been initiated...
  15. ncbi request reprint P2Y2 receptor-mediated release of prostaglandin E2 by IMCD is altered in hydrated and dehydrated rats: relevance to AVP-independent regulation of IMCD function
    Rujia Sun
    Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah, USA
    Am J Physiol Renal Physiol 289:F585-92. 2005
    ..In conclusion, the increased sensitivity of purinergic-prostanoid interaction seen in the IMCD of hydrated rats may represent a novel vasopressin-independent regulatory mechanism of IMCD function...
  16. pmc Long-term daclizumab therapy in relapsing-remitting multiple sclerosis
    Monica A Rojas
    Neurovirology Research Laboratory, VASLCHCS and Department of Neurology, University of Utah, Salt Lake City, UT, USA
    Ther Adv Neurol Disord 2:291-7. 2009
    ..0001). Long-term treatment with daclizumab in RR MS patients has apparent benefit that will require formal confirmation...
  17. doi request reprint Clinical biomarkers in multiple sclerosis
    John W Rose
    University of Utah, Neurology Service, VASLCHCS, Salt Lake City, UT 84148, USA
    Expert Opin Med Diagn 5:213-26. 2011
    ....
  18. ncbi request reprint Monoclonal antibody treatments for multiple sclerosis
    John W Rose
    John W Rose, MD Neurovirology Research Laboratory, VA Salt Lake City Health Care System and Department of Neurology, University of Utah Neurovirology Research Laboratory 151B, 500 Foothill Drive, Salt Lake City, UT 84148, USA
    Curr Treat Options Neurol 11:211-20. 2009
    ..Adverse effects are relatively mild for these MAbs; however, care in administration and management of these agents is emphasized. Overall, these MAb therapies have great promise in the treatment of MS...
  19. ncbi request reprint Neuroprotection of cultured cortical neurons mediated by the cyclooxygenase-2 inhibitor APHS can be reversed by a prostanoid
    Noel G Carlson
    Salt Lake City VA Geriatrics Research, Education and Clinical Center, Salt Lake City, Utah, USA
    J Neurosci Res 71:79-88. 2003
    ..PGE(2) may in some instances contribute toward excitotoxicity, and the inhibition of synthesis of this prostanoid may in part explain the neuroprotective properties of these COX-2 inhibitors...