M B Leon

Summary

Affiliation: Cardiovascular Research Foundation
Country: USA

Publications

  1. ncbi request reprint Paravalvular leak after transcatheter aortic valve replacement
    P Genereux
    Columbia University Medical Center New York Presbyterian Hospital New York, NY, USA
    Minerva Cardioangiol 61:529-37. 2013
  2. doi request reprint Standardized endpoint definitions for Transcatheter Aortic Valve Implantation clinical trials: a consensus report from the Valve Academic Research Consortium
    Martin B Leon
    Columbia University Medical Center, New York, New York 10032, USA
    J Am Coll Cardiol 57:253-69. 2011
  3. doi request reprint Late safety, efficacy, and cost-effectiveness of a zotarolimus-eluting stent compared with a paclitaxel-eluting stent in patients with de novo coronary lesions: 2-year follow-up from the ENDEAVOR IV trial (Randomized, Controlled Trial of the Medtronic End
    Martin B Leon
    Columbia University Medical Center and the Cardiovascular Research Foundation, New York, New York 10032, USA
    JACC Cardiovasc Interv 2:1208-18. 2009
  4. doi request reprint Late clinical events after drug-eluting stents: the interplay between stent-related and natural history-driven events
    Martin B Leon
    Center for Interventional Vascular Therapy, Columbia University Medical Center, Herbert Irving Pavilion, New York, NY 10032, USA
    JACC Cardiovasc Interv 2:504-12. 2009
  5. doi request reprint A randomized comparison of the Endeavor zotarolimus-eluting stent versus the TAXUS paclitaxel-eluting stent in de novo native coronary lesions 12-month outcomes from the ENDEAVOR IV trial
    Martin B Leon
    Columbia University Medical Center and the Cardiovascular Research Foundation, New York, New York, USA
    J Am Coll Cardiol 55:543-54. 2010
  6. ncbi request reprint A blinded, randomized, placebo-controlled trial of percutaneous laser myocardial revascularization to improve angina symptoms in patients with severe coronary disease
    Martin B Leon
    Cardiovascular Research Foundation, Center for Interventional Vascular Therapy, Columbia University Medical Center, New York, New York 10032, USA
    J Am Coll Cardiol 46:1812-9. 2005
  7. ncbi request reprint Transcatheter aortic valve replacement in patients with critical aortic stenosis: rationale, device descriptions, early clinical experiences, and perspectives
    Martin B Leon
    Columbia University Medical Center, New York, NY 10032, USA
    Semin Thorac Cardiovasc Surg 18:165-74. 2006
  8. doi request reprint Improved late clinical safety with zotarolimus-eluting stents compared with paclitaxel-eluting stents in patients with de novo coronary lesions: 3-year follow-up from the ENDEAVOR IV (Randomized Comparison of Zotarolimus- and Paclitaxel-Eluting Stents in
    Martin B Leon
    Columbia University Medical Center, New York, New York 10032, USA
    JACC Cardiovasc Interv 3:1043-50. 2010
  9. ncbi request reprint Localized intracoronary gamma-radiation therapy to inhibit the recurrence of restenosis after stenting
    M B Leon
    Cardiovascular Research Foundation, Lenox Hill Hospital, New York, NY 10021, USA
    N Engl J Med 344:250-6. 2001
  10. pmc Standardized endpoint definitions for transcatheter aortic valve implantation clinical trials: a consensus report from the Valve Academic Research Consortium
    Martin B Leon
    Columbia University Medical Center, Center for Interventional Vascular Therapy, 173 Fort Washington Avenue, Heart Center, New York, NY 10032, USA
    Eur Heart J 32:205-17. 2011

Collaborators

Detail Information

Publications119 found, 100 shown here

  1. ncbi request reprint Paravalvular leak after transcatheter aortic valve replacement
    P Genereux
    Columbia University Medical Center New York Presbyterian Hospital New York, NY, USA
    Minerva Cardioangiol 61:529-37. 2013
    ....
  2. doi request reprint Standardized endpoint definitions for Transcatheter Aortic Valve Implantation clinical trials: a consensus report from the Valve Academic Research Consortium
    Martin B Leon
    Columbia University Medical Center, New York, New York 10032, USA
    J Am Coll Cardiol 57:253-69. 2011
    ..To make these consensus definitions accessible to all stakeholders in TAVI clinical research through a peer reviewed publication, on behalf of the public health...
  3. doi request reprint Late safety, efficacy, and cost-effectiveness of a zotarolimus-eluting stent compared with a paclitaxel-eluting stent in patients with de novo coronary lesions: 2-year follow-up from the ENDEAVOR IV trial (Randomized, Controlled Trial of the Medtronic End
    Martin B Leon
    Columbia University Medical Center and the Cardiovascular Research Foundation, New York, New York 10032, USA
    JACC Cardiovasc Interv 2:1208-18. 2009
    ..The aim of this study was to assess, after 2 years of follow-up, the safety, efficacy, and cost-effectiveness of a zotarolimus-eluting stent (ZES) compared with a paclitaxel-eluting stent (PES) in patients with native coronary lesions...
  4. doi request reprint Late clinical events after drug-eluting stents: the interplay between stent-related and natural history-driven events
    Martin B Leon
    Center for Interventional Vascular Therapy, Columbia University Medical Center, Herbert Irving Pavilion, New York, NY 10032, USA
    JACC Cardiovasc Interv 2:504-12. 2009
    ....
  5. doi request reprint A randomized comparison of the Endeavor zotarolimus-eluting stent versus the TAXUS paclitaxel-eluting stent in de novo native coronary lesions 12-month outcomes from the ENDEAVOR IV trial
    Martin B Leon
    Columbia University Medical Center and the Cardiovascular Research Foundation, New York, New York, USA
    J Am Coll Cardiol 55:543-54. 2010
    ....
  6. ncbi request reprint A blinded, randomized, placebo-controlled trial of percutaneous laser myocardial revascularization to improve angina symptoms in patients with severe coronary disease
    Martin B Leon
    Cardiovascular Research Foundation, Center for Interventional Vascular Therapy, Columbia University Medical Center, New York, New York 10032, USA
    J Am Coll Cardiol 46:1812-9. 2005
    ..This study was a randomized, patient- and evaluator-blinded, placebo-controlled trial in patients treated using percutaneous myocardial laser revascularization...
  7. ncbi request reprint Transcatheter aortic valve replacement in patients with critical aortic stenosis: rationale, device descriptions, early clinical experiences, and perspectives
    Martin B Leon
    Columbia University Medical Center, New York, NY 10032, USA
    Semin Thorac Cardiovasc Surg 18:165-74. 2006
    ....
  8. doi request reprint Improved late clinical safety with zotarolimus-eluting stents compared with paclitaxel-eluting stents in patients with de novo coronary lesions: 3-year follow-up from the ENDEAVOR IV (Randomized Comparison of Zotarolimus- and Paclitaxel-Eluting Stents in
    Martin B Leon
    Columbia University Medical Center, New York, New York 10032, USA
    JACC Cardiovasc Interv 3:1043-50. 2010
    ..The increased frequency of very late (>1 year) stent thrombosis (VLST) has raised concerns with regard to the safety of sirolimus-eluting stents and paclitaxel-eluting stents (PES)...
  9. ncbi request reprint Localized intracoronary gamma-radiation therapy to inhibit the recurrence of restenosis after stenting
    M B Leon
    Cardiovascular Research Foundation, Lenox Hill Hospital, New York, NY 10021, USA
    N Engl J Med 344:250-6. 2001
    ..We report on a multicenter, double-blind, randomized trial of intracoronary radiation therapy for the treatment of in-stent restenosis...
  10. pmc Standardized endpoint definitions for transcatheter aortic valve implantation clinical trials: a consensus report from the Valve Academic Research Consortium
    Martin B Leon
    Columbia University Medical Center, Center for Interventional Vascular Therapy, 173 Fort Washington Avenue, Heart Center, New York, NY 10032, USA
    Eur Heart J 32:205-17. 2011
    ..To make these consensus definitions accessible to all stakeholders in TAVI clinical research through a peer reviewed publication, on behalf of the public health...
  11. ncbi request reprint Acute and long-term results of treatment of diffuse in-stent restenosis in aortocoronary saphenous vein grafts
    G Dangas
    Cardiovascular Research Foundation, New York, New York 10022, USA
    Am J Cardiol 86:777-9, A6. 2000
    ..However, this population has high long-term mortality and frequent need for repeat revascularization...
  12. doi request reprint Transcatheter versus surgical aortic-valve replacement in high-risk patients
    Craig R Smith
    Columbia University Medical Center New York Presbyterian Hospital, New York, NY 10032, USA
    N Engl J Med 364:2187-98. 2011
    ..However, the two procedures have not been compared in a randomized trial involving high-risk patients who are still candidates for surgical replacement...
  13. ncbi request reprint Influence of gender on early and one-year clinical outcomes after saphenous vein graft stenting
    J M Ahmed
    Cardiovascular Research Foundation, New York, New York 10022, USA
    Am J Cardiol 87:401-5. 2001
    ....
  14. ncbi request reprint Combination therapy with aspirin plus clopidogrel versus aspirin plus ticlopidine for prevention of subacute thrombosis after successful native coronary stenting
    G Dangas
    Cardiovascular Research Foundation, New York, New York 10022, USA
    Am J Cardiol 87:470-2, A7. 2001
    ..At 30-day follow-up, there were trends toward increased subacute thrombosis with A+C compared with A+T (1.3% vs 0.2%, p = 0.10). These results suggest that A+C may have marginally higher subacute stent thrombosis than A+T...
  15. ncbi request reprint Treatment of focal in-stent restenosis with balloon angioplasty alone versus stenting: Short- and long-term results
    R Mehran
    Cardiovascular Research Foundation, 55 E 59th St, New York, NY 10022, USA
    Am Heart J 141:610-4. 2001
    ..2-4.7, P =.01). CONCLUSION: Repeat stenting for the treatment of focal ISR had a higher postprocedure creatine kinase myocardial band elevation rate and similar long-term clinical results compared with PTCA alone...
  16. ncbi request reprint Carotid artery stenting in patients with high-risk anatomy for carotid endarterectomy
    G Dangas
    Knox Hill Heart and Vascular Institute, Cardiovascular Research Foundation, New York, New York 10022, USA
    J Endovasc Ther 8:39-43. 2001
    ..To report the results of carotid artery stenting (CAS) in patients considered to have high-risk anatomical characteristics for carotid endarterectomy...
  17. ncbi request reprint Safety and efficacy of sirolimus- and paclitaxel-eluting coronary stents
    Gregg W Stone
    Columbia University Medical Center and the Cardiovascular Research Foundation, New York, NY 10022, USA
    N Engl J Med 356:998-1008. 2007
    ..Such studies have been inconclusive because of their insufficient size, the use of historical controls, a limited duration of follow-up, and a lack of access to original source data...
  18. ncbi request reprint Impact of sirolimus-eluting stents on outcome in diabetic patients: a SIRIUS (SIRolImUS-coated Bx Velocity balloon-expandable stent in the treatment of patients with de novo coronary artery lesions) substudy
    Issam Moussa
    Lenox Hill Heart and Vascular Institute and Cardiovascular Research Foundation, 130 East 77th St, 9th Floor, New York, NY 10021, USA
    Circulation 109:2273-8. 2004
    ..The purpose of this analysis was to determine the impact of sirolimus-eluting stents on outcomes of diabetic compared with nondiabetic patients...
  19. ncbi request reprint Intravascular ultrasound-guided renal artery stenting
    G Dangas
    Cardiovascular Research Foundation, New York, New York 10022, USA
    J Endovasc Ther 8:238-47. 2001
    ..To evaluate the clinical outcomes of patients undergoing renal artery stenting with intravascular ultrasound (IVUS) guidance and compare measurements between IVUS and angiography...
  20. ncbi request reprint Evaluation of the acute and chronic safety of the biosense injection catheter system in porcine hearts
    R Kornowski
    Cardiovascular Research Foundation, Washington Hospital Center, Washington, D C 20010, USA
    Catheter Cardiovasc Interv 48:447-53; discussion 454-5. 1999
    ..Cathet. Cardiovasc. Intervent. 48:447-453, 1999...
  21. ncbi request reprint Delivery strategies to achieve therapeutic myocardial angiogenesis
    R Kornowski
    Cardiovascular Research Foundation, Washington Hospital Center, Washington DC 20010, USA
    Circulation 101:454-8. 2000
    ..In this article, we review the different modes of administration for therapeutic myocardial angiogenesis therapy...
  22. ncbi request reprint Impact of obesity on revascularization and restenosis rates after bare-metal and drug-eluting stent implantation (from the TAXUS-IV trial)
    Eugenia Nikolsky
    Cardiovascular Research Foundation, New York, New York 10022, USA
    Am J Cardiol 95:709-15. 2005
    ..Paclitaxel-eluting stents attenuate the increased risk associated with obesity, such that the intermediate-term prognosis after percutaneous coronary intervention is independent of weight...
  23. ncbi request reprint Update on drug-eluting coronary stents
    Nicholas N Kipshidze
    Department of Interventional Cardiac and Vascular Services, Lenox Hill Hospital, New York, NY 10021, USA
    Expert Rev Cardiovasc Ther 3:953-68. 2005
    ..Recent advances in vascular gene transfer have also demonstrated potential new treatment modalities for cardiovascular disease, particularly in the treatment of vascular restenosis...
  24. ncbi request reprint Effect of everolimus-eluting stents in different vessel sizes (from the pooled FUTURE I and II trials)
    Yoshihiro Tsuchiya
    The Cardiovascular Research Foundation and Columbia University Medical Center, New York, New York, USA
    Am J Cardiol 98:464-9. 2006
    ..The EES appears to be effective for treatment of de novo coronary lesions in decreasing neointimal proliferation at 6-month follow-up compared with BMSs, regardless of vessel size...
  25. ncbi request reprint Short- and long-term outcomes after stent-assisted percutaneous treatment of saphenous vein grafts in the drug-eluting stent era
    Tereza Pucelikova
    Columbia University Medical Center and the Cardiovascular Research Foundation, New York, NY, USA
    Am J Cardiol 101:63-8. 2008
    ..025). In conclusion, our data show that patients with SVG lesions remain a high-risk subgroup with worse outcomes after percutaneous coronary intervention compared with native vessel disease even in the era of drug-eluting stents...
  26. doi request reprint Effectiveness of drug-eluting stent implantation for patients with unprotected left main coronary artery stenosis
    Young Hak Kim
    Columbia University Medical Center and the Cardiovascular Research Foundation, New York, New York, USA
    Am J Cardiol 101:801-6. 2008
    ..However, bifurcation stenosis remains a significant predictor of unfavorable clinical outcome...
  27. doi request reprint Comparison between ticlopidine and clopidogrel in patients undergoing primary stenting in acute myocardial infarction: results from the CADILLAC trial
    Alexandra J Lansky
    Columbia University Medical Center, Department of Cardiology, Cardiovascular Research Foundation, New York, New York 10022, USA
    Catheter Cardiovasc Interv 72:917-24. 2008
    ..The aim of this article is to examine whether clopidogrel and ticlopidine treatments produce similar clinical outcomes for patients receiving primary stenting for acute myocardial infarction (AMI)...
  28. doi request reprint Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery
    Martin B Leon
    Columbia University Medical Center NewYork Presbyterian Hospital, New York, NY 10032, USA
    N Engl J Med 363:1597-607. 2010
    ..Recently, transcatheter aortic-valve implantation (TAVI) has been suggested as a less invasive treatment for high-risk patients with aortic stenosis...
  29. ncbi request reprint Photoactivation of vascular iNOS and elevation of cGMP in vivo: possible mechanism for photovasorelaxation and inhibition of restenosis in an atherosclerotic rabbit models
    N Kipshidze
    Lenox Hill Heart and Vascular Institute, New York, NY, USA
    Photochem Photobiol 72:579-82. 2000
    ..Balloon + laser treatment, however, tended to restore the expression of iNOS. Our study demonstrated that intravascular low dose laser irradiation induces iNOS and elevates vascular cGMP in an in vivo atherosclerotic rabbit model...
  30. ncbi request reprint Effect of the distal-balloon protection system on microembolization during carotid stenting
    N Al-Mubarak
    Lenox Hill Heart and Vascular Institute, New York, NY, USA
    Circulation 104:1999-2002. 2001
    ..The distal-balloon protection system significantly reduced the frequency of MES during CAS, particularly during these 3 phases...
  31. doi request reprint Intravascular ultrasound comparison of the retrograde versus antegrade approach to percutaneous intervention for chronic total coronary occlusions
    Kenichi Tsujita
    Cardiovascular Research Foundation and Columbia University Medical Center, New York, New York 10022, USA
    JACC Cardiovasc Interv 2:846-54. 2009
    ..We sought to evaluate the results of the antegrade versus retrograde chronic total occlusion (CTO) technique with intravascular ultrasound (IVUS) imaging...
  32. ncbi request reprint Effect of percutaneous coronary interventions for in-stent restenosis in degenerated saphenous vein grafts without distal embolic protection
    Dale T Ashby
    Lenox Hill Heart and Vascular Institute, New York, New York, USA
    J Am Coll Cardiol 41:749-52. 2003
    ..This study was designed to investigate the impact of percutaneous coronary interventions (PCIs) in degenerated saphenous vein grafts (SVGs) without distal embolic protection...
  33. ncbi request reprint Increased CK-MB release is a "trade-off" for optimal stent implantation: an intravascular ultrasound study
    Ioannis Iakovou
    Cardiovascular Research Foundation, Lenox Hill Heart and Vascular Institute, New York, New York 10022, USA
    J Am Coll Cardiol 42:1900-5. 2003
    ..We sought to determine the impact of aggressive stent expansion on creatine kinase-MB isoenzyme (CK-MB) release and clinical restenosis...
  34. ncbi request reprint Novel site-specific systemic delivery of Rapamycin with perfluorobutane gas microbubble carrier reduced neointimal formation in a porcine coronary restenosis model
    Nicholas N Kipshidze
    Department of Interventional Cardiac and Vascular Services, Lenox Hill Hospital, New York, NY 10021, USA
    Catheter Cardiovasc Interv 64:389-94. 2005
    ..001). In the porcine coronary model, site-specific systemic delivery of Rapamycin utilizing PGMC resulted in overexpression of p27 and a significant reduction of neointimal formation within the stented segments...
  35. doi request reprint Clinical and angiographic outcomes in diabetics from the ENDEAVOR IV trial: randomized comparison of zotarolimus- and paclitaxel-eluting stents in patients with coronary artery disease
    Ajay J Kirtane
    Columbia University Medical Center and the Cardiovascular Research Foundation, New York, New York, USA
    JACC Cardiovasc Interv 2:967-76. 2009
    ..Natick, Massachusetts) in the 477 patients with diabetes mellitus (DM) enrolled in the randomized ENDEAVOR IV (Randomized Comparison of Zotarolimus- and Paclitaxel-Eluting Stents in Patients with Coronary Artery Disease) trial...
  36. ncbi request reprint A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validation
    Roxana Mehran
    Cardiovascular Research Foundation, Columbia University Medical Center, New York, New York 10022, USA
    J Am Coll Cardiol 44:1393-9. 2004
    ..We sought to develop a simple risk score of contrast-induced nephropathy (CIN) after percutaneous coronary intervention (PCI)...
  37. ncbi request reprint Nonuniform strut distribution correlates with more neointimal hyperplasia after sirolimus-eluting stent implantation
    Hideo Takebayashi
    Cardiovascular Research Foundation, Lenox Hill Heart and Vascular Institute, New York, NY 10022, USA
    Circulation 110:3430-4. 2004
    ..Little is known about causes of intimal hyperplasia (IH) after sirolimus-eluting stent (SES) implantation...
  38. ncbi request reprint Successful use of the frontrunner catheter in the treatment of in-stent coronary chronic total occlusions
    Yi ming Yang
    Columbia University Medical Center and Cardiovascular Research Foundation, 161 Fort Washington Avenue, New York, NY 10032, USA
    Catheter Cardiovasc Interv 63:462-8. 2004
    ..TIMI 3 flow was achieved in all target vessels after further balloon angioplasty or stenting. The Frontrunner device is a safe and effective tool in the treatment of CTOs from ISR...
  39. ncbi request reprint Creatine kinase-MB enzyme elevation and long-term clinical events after successful coronary stenting in lesions with ruptured plaque
    Kenichi Fujii
    Cardiovascular Research Foundation, Lenox Hill Heart and Vascular Institute, New York, New York, USA
    Am J Cardiol 95:355-9. 2005
    ..Plaque rupture morphology is associated with higher periprocedural CK-MB release and worse 1-year clinical outcome in patients treated with coronary stenting...
  40. ncbi request reprint Gender-based outcomes after paclitaxel-eluting stent implantation in patients with coronary artery disease
    Alexandra J Lansky
    Columbia University Medical Center and Cardiovascular Research Foundation, New York, New York, USA
    J Am Coll Cardiol 45:1180-5. 2005
    ..We sought to determine whether gender influences the results of paclitaxel-eluting stent implantation...
  41. ncbi request reprint Clinical outcomes after heterogeneous overlap stenting with drug-eluting stents and bare-metal stents for de novo coronary artery narrowings
    Jiro Aoki
    Center for Interventional Vascular Therapy, Columbia University Medical Center, New York, NY, USA
    Am J Cardiol 101:58-62. 2008
    ..In conclusion, the incidence of DES and BMS overlap stenting is rare in daily practice, but this procedure is associated with a high rate of target vessel revascularization...
  42. ncbi request reprint An evaluation of fluoroscopy time and correlation with outcomes after percutaneous coronary intervention
    Eugenia Nikolsky
    Columbia University Medical Center and the Cardiovascular Research Foundation, New York City, NY 10022, USA
    J Invasive Cardiol 19:208-13. 2007
    ..We evaluated short-term prognosis and resource utilization of consecutive patients treated with percutaneous coronary intervention (PCI) as a function of fluoroscopy time...
  43. doi request reprint Early stent thrombosis in patients with acute coronary syndromes treated with drug-eluting and bare metal stents: the Acute Catheterization and Urgent Intervention Triage Strategy trial
    Jiro Aoki
    Columbia University Medical Center and the Cardiovascular Research Foundation, New York, NY, USA
    Circulation 119:687-98. 2009
    ..The clinical and angiographic predictors of early (<30 days) stent thrombosis (ST) have not been reported in high-risk patients with acute coronary syndromes...
  44. ncbi request reprint Angiographic results of the first human experience with the Biolimus A9 drug-eluting stent for de novo coronary lesions
    Ricardo A Costa
    The Cardiovascular Research Foundation and Columbia University Medical Center, New York, New York, USA
    Am J Cardiol 98:443-6. 2006
    ..14 +/- 0.45 vs 0.40 +/- 0.41 mm, p = 0.004). In-stent restenosis was 3.9% in the Biolimus stent group versus 7.7% in the control group (p = 0.40). There was no exaggerated hyperplasia at the proximal and/or distal edge of the stent...
  45. ncbi request reprint Outcome after acute incomplete sirolimus-eluting stent apposition as assessed by serial intravascular ultrasound
    Masashi Kimura
    The Columbia University Medical Center and Cardiovascular Research Foundation, New York, New York, USA
    Am J Cardiol 98:436-42. 2006
    ..Although most ISAs after SES implantation do not resolve completely, the incidence of restenosis or thrombosis is not affected...
  46. ncbi request reprint Frequency and determinants of black holes in sirolimus-eluting stent restenosis
    Jose de Ribamar Costa
    Cardiovascular Research Foundation and Columbia University Medical Center, New York, New York, USA
    J Invasive Cardiol 18:348-52. 2006
    ..We sought to investigate the frequency and determinants of black holes (BH) after sirolimus-eluting stent (SES) implantation...
  47. ncbi request reprint Two-year outcomes after sirolimus-eluting stent implantation: results from the Sirolimus-Eluting Stent in de Novo Native Coronary Lesions (SIRIUS) trial
    Giora Weisz
    Cardiovascular Research Foundation and Columbia University Medical Center, New York, New York 10032, USA
    J Am Coll Cardiol 47:1350-5. 2006
    ..The purpose of this study was to examine the two-year clinical outcomes in patients enrolled in the Sirolimus-Eluting Stent in De Novo Native Coronary Lesions (SIRIUS) study...
  48. doi request reprint 5-year clinical outcomes after sirolimus-eluting stent implantation insights from a patient-level pooled analysis of 4 randomized trials comparing sirolimus-eluting stents with bare-metal stents
    Adriano Caixeta
    Columbia University Medical Center and the Cardiovascular Research Foundation, New York, New York, USA
    J Am Coll Cardiol 54:894-902. 2009
    ..Five-year clinical follow-up has been scheduled per protocol by the 4 Cypher (Cordis/Johnson & Johnson, Warren, New Jersey) sirolimus-eluting stent (SES) versus bare-metal stent (BMS) randomized trials...
  49. ncbi request reprint Impact of chronic kidney disease on prognosis of patients with diabetes mellitus treated with percutaneous coronary intervention
    Eugenia Nikolsky
    Cardiovascular Research Foundation, and Lenox Hill Heart and Vascular Institute, New York, New York, USA
    Am J Cardiol 94:300-5. 2004
    ..Contrast-induced nephropathy was among the independent predictors of a 1-year mortality rate (OR 2.75, p <0.001)...
  50. ncbi request reprint Comparison of clinical outcomes using stents versus no stents after percutaneous coronary intervention for proximal left anterior descending versus proximal right and left circumflex coronary arteries
    Dale T Ashby
    Cardiovascular Research Foundation, Lenox Hill Heart and Vascualr Institute, New York, New York 10022, USA
    Am J Cardiol 89:1162-6. 2002
    ..A stenting strategy for proximal LAD stenoses appears to attenuate the differences of clinical restenosis noted after non-stent PCI...
  51. ncbi request reprint Bifurcation stenting with drug-eluting stents: a systematic review and meta-analysis of randomised trials
    Somjot S Brar
    Columbia University Medical Center, New York, NY, USA
    EuroIntervention 5:475-84. 2009
    ....
  52. ncbi request reprint Intravascular brachytherapy for native coronary ostial in-stent restenotic lesions
    Costantino O Costantini
    Cardiovascular Research Foundation, Lenox Hill Hospital, 55 East 59th Street, 6th Floor, New York, New York, NY 10022, USA
    J Am Coll Cardiol 41:1725-31. 2003
    ..We analyzed the effects of vascular brachytherapy (VBT) on ostial in-stent restenosis (ISR)...
  53. ncbi request reprint Differential impact on survival of electrocardiographic Q-wave versus enzymatic myocardial infarction after percutaneous intervention: a device-specific analysis of 7147 patients
    G W Stone
    Cardiovascular Research Foundation, Lenox Hill Heart and Vascular Institute, New York City, NY, USA
    Circulation 104:642-7. 2001
    ..Large periprocedural infarctions (signified by new Q waves and CPK-MB >8xULN) are powerful determinants of death, whereas lesser degrees of CPK-MB release and specific device use do not adversely affect survival...
  54. ncbi request reprint Intravascular ultrasound assessment of drug-eluting stent expansion
    Jose de Ribamar Costa
    Cardiovascular Research Foundation and Columbia University Medical Center, New York, NY, USA
    Am Heart J 153:297-303. 2007
    ....
  55. ncbi request reprint Correlation of coronary arterial remodeling determined by intravascular ultrasound with angiographic diameter reduction of 20% to 60%
    Makoto Hirose
    Cardiovascular Research Foundation, New York, NY 10021, USA
    Am J Cardiol 92:141-5. 2003
    ..7) were similar. Negative remodeling is frequently observed in lesions with intermediate stenosis. This suggests that negative remodeling occurs early in lesion formation...
  56. ncbi request reprint Bifurcation coronary lesions treated with the "crush" technique: an intravascular ultrasound analysis
    Ricardo A Costa
    Cardiovascular Research Foundation and Columbia University Medical Center, New York, New York 10022, USA
    J Am Coll Cardiol 46:599-605. 2005
    ..We report intravascular ultrasound (IVUS) findings after crush-stenting of bifurcation lesions...
  57. ncbi request reprint Contribution of stent underexpansion to recurrence after sirolimus-eluting stent implantation for in-stent restenosis
    Kenichi Fujii
    Cardiovascular Research Foundation, Lenox Hill Heart and Vascular Institute, New York, NY 10021, USA
    Circulation 109:1085-8. 2004
    ..We used intravascular ultrasound (IVUS) to evaluate recurrence after sirolimus-eluting stent (SES) implantation treatment of in-stent restenosis (ISR)...
  58. doi request reprint Impact of platelet glycoprotein IIb/IIIa receptor inhibitors on outcomes of diabetic patients undergoing percutaneous coronary interventions using sirolimus-eluting stents
    Eugenia Nikolsky
    Columbia University Medical Center, Center for Interventional Vascular Therapy and the Cardiovascular Research Foundation, New York, NY 10022, USA
    Catheter Cardiovasc Interv 71:896-906. 2008
    ..We assessed the outcomes in diabetic patients undergoing percutaneous coronary intervention (PCI) using sirolimus-eluting stents (SES) as a function of treatment with glycoprotein (GP) IIb/IIIa inhibitors...
  59. ncbi request reprint Impact of coronary culprit lesion calcium in patients undergoing paclitaxel-eluting stent implantation (a TAXUS-IV sub study)
    Issam Moussa
    Cardiovascular Research Foundation and Columbia University Medical Center, New York, NY, USA
    Am J Cardiol 96:1242-7. 2005
    ..30 and 0.26, respectively). In conclusion, implantation of paclitaxel-eluting stents in patients with de novo coronary lesions significantly reduced restenosis in patients with and without calcified lesions...
  60. ncbi request reprint Drug-eluting stents in the treatment of intermediate lesions: pooled analysis from four randomized trials
    Jeffrey W Moses
    Columbia University Medical Center and the Cardiovascular Research Foundation, New York, New York 10032, USA
    J Am Coll Cardiol 47:2164-71. 2006
    ....
  61. ncbi request reprint The relative effects of abciximab and tirofiban on platelet inhibition and C-reactive protein during coronary intervention
    Adam J Saltzman
    Cardiovascular Medicine and the Center for Interventional Vascular Therapy, Columbia University Medical Center, 161 Fort Washington Avenue, New York, NY, 10032, USA
    J Invasive Cardiol 22:2-6. 2010
    ..We sought to compare the efficacy of tirofiban and abciximab on platelet inhibition as well as their effects of platelet inhibition on C-reactive protein levels during percutaneous coronary intervention (PCI)...
  62. doi request reprint Intravascular ultrasound assessment of the incidence and predictors of edge dissections after drug-eluting stent implantation
    Xuebo Liu
    Columbia University Medical Center and Cardiovascular Research Foundation, New York, New York, USA
    JACC Cardiovasc Interv 2:997-1004. 2009
    ..We used intravascular ultrasound (IVUS) to assess incidence, predictors, morphology, and angiographic findings of edge dissections after drug-eluting stent (DES) implantation...
  63. ncbi request reprint Stent underexpansion and residual reference segment stenosis are related to stent thrombosis after sirolimus-eluting stent implantation: an intravascular ultrasound study
    Kenichi Fujii
    Cardiovascular Research Foundation, Columbia University Medical Center, 55 East 59th Street, New York, NY 10022, USA
    J Am Coll Cardiol 45:995-8. 2005
    ..We sought to determine the predictors of stent thrombosis after sirolimus-eluting stent (SES) implantation...
  64. ncbi request reprint Optimal final lumen area and predictors of target lesion revascularization after stent implantation in small coronary arteries
    Ioannis Iakovou
    Cardiovascular Research Foundation, Lenox Hill Heart and Vascular Institute, New York, New York 10022, USA
    Am J Cardiol 92:1171-6. 2003
    ..Therefore, there does not appear to be any "downside" to aggressive stent implantation strategies in small vessels. In contrast, IVUS allows maximization of final lumen dimensions to minimize clinical restenosis...
  65. ncbi request reprint Nonrandomized comparison of coronary stenting under intravascular ultrasound guidance of direct stenting without predilation versus conventional predilation with a semi-compliant balloon versus predilation with a new scoring balloon
    Jose de Ribamar Costa
    Cardiovascular Research Foundation and Columbia University Medical Center, New York, New York, USA
    Am J Cardiol 100:812-7. 2007
    ..In conclusion, in this observational, nonrandomized study, pretreatment with the AngioSculpt balloon enhanced stent expansion and minimized the difference between predicted and achieved stent dimensions...
  66. ncbi request reprint Advanced c-myc antisense (AVI-4126)-eluting phosphorylcholine-coated stent implantation is associated with complete vascular healing and reduced neointimal formation in the porcine coronary restenosis model
    Nicholas N Kipshidze
    Lenox Hill Heart and Vascular Institute and Cardiovascular Research Foundation, New York, New York 10021, USA
    Catheter Cardiovasc Interv 61:518-27. 2004
    ..In the porcine coronary model, an advanced c-myc-eluting PC stent blocked c-myc expression and significantly inhibited myointimal hyperplasia and allowed complete reendothelialization and healing response...
  67. doi request reprint Impact of gender and age on in vivo virtual histology-intravascular ultrasound imaging plaque characterization (from the global Virtual Histology Intravascular Ultrasound [VH-IVUS] registry)
    Jie Qian
    Cardiovascular Research Foundation and Columbia University Medical Center, New York, New York, USA
    Am J Cardiol 103:1210-4. 2009
    ....
  68. ncbi request reprint Feasibility and efficacy of tandem positioning on angiographic and clinical outcomes in the Intimal Hyperplasia Inhibition with Beta In-Stent Trial
    Kazuyuki Shirai
    Cardiovascular Research Foundation, Lenox Hill Hospital, New York, New York 10022, USA
    Am J Cardiol 91:1113-5. 2003
  69. ncbi request reprint Implications of the presence and length of "geographic miss" on restenosis and the edge phenomenon in the INHIBIT trial
    Costantino O Costantini
    Cardiovascular Research Foundation, New York, New York 10022, USA
    Am J Cardiol 91:1261-5. 2003
  70. ncbi request reprint Comparison of the angiographic outcomes after beta versus gamma vascular brachytherapy for treatment of in-stent restenosis
    Kazuyuki Shirai
    Cardiovascular Research Foundation, Lenox Hill Hospital, New York, New York 10022, USA
    Am J Cardiol 92:1409-13. 2003
    ..In matched lesions, beta and gamma VBT achieved similar reductions in treated segment restenosis and recurrent lesion length compared with placebo...
  71. ncbi request reprint Intravascular ultrasound assessment of lesions with target vessel failure after sirolimus-eluting stent implantation
    Hideo Takebayashi
    Cardiovascular Research Foundation, New York, New York, USA
    Am J Cardiol 95:498-502. 2005
    ....
  72. ncbi request reprint Effect of catheter-based iridium-192 gamma brachytherapy on the added risk of restenosis from diabetes mellitus after intervention for in-stent restenosis (subanalysis of the GAMMA I Randomized Trial)
    Jeffrey W Moses
    Lenox Hill Heart and Vascular Institute and Cardiovascular Research Foundation, New York, New York 10021, USA
    Am J Cardiol 90:243-7. 2002
    ..The relative impact of this treatment is more pronounced in diabetic patients because it appears to neutralize the added risk of recurrent restenosis seen in proliferative diabetic lesions...
  73. ncbi request reprint Relation between the degree of procedural anticoagulation and complications after coronary stent implantation
    Dale T Ashby
    Cardiovascular Research Foundation and Lenox Hill Heart and Vascular Institute, New York, New York 10022, USA
    Am J Cardiol 92:319-22. 2003
    ..High levels of procedural anticoagulation with heparin were found to increase hemorrhagic complications without improving clinical or angiographic outcomes...
  74. ncbi request reprint Low-power laser irradiation increases cyclic GMP synthesis in penile smooth muscle cells in vitro
    N Kipshidze
    Lenox Hill Heart and Vascular Institute of New York, Cardiovascular Research Foundation, New York, New York 10021, USA
    J Clin Laser Med Surg 18:291-4. 2000
    ..The objective of the present study was to determine the effect of low-power laser irradiation (LPLI) on cyclic guanosine monophosphate (cGMP) produced by human corpus cavernosum smooth muscle cells (HCC SMC) in vitro...
  75. ncbi request reprint Transient contrast encephalopathy after carotid artery stenting
    G Dangas
    Cardiovascular Research Foundation, Lenox Hill Heart and Vascular Institute, New York, New York 10022, USA
    J Endovasc Ther 8:111-3. 2001
    ..To report an unusual case of transient contrast encephalopathy arising after carotid artery stenting...
  76. ncbi request reprint Relation between preintervention remodeling and late arterial responses to coronary angioplasty or atherectomy
    G S Mintz
    Cardiovascular Research Foundation, New York, New York, USA
    Am J Cardiol 87:392-6. 2001
    ..This may explain that the increased clinical restenosis after positive remodeling lesions is treated with non-stent interventions...
  77. ncbi request reprint Association of plaque characterization by intravascular ultrasound virtual histology and arterial remodeling
    Kenichi Fujii
    Columbia University Medical Center and Cardiovascular Research Foundation, New York, New York, USA
    Am J Cardiol 96:1476-83. 2005
    ..26, p=0.02). In conclusion, in vivo IVUS radiofrequency data analysis demonstrates that positive remodeling occurs in lesions with more fibrofatty plaque...
  78. ncbi request reprint Usefulness of the angiographic pattern of in-stent restenosis in predicting the success of gamma vascular brachytherapy
    Costantino O Costantini
    Cardiovascular Research Foundation, New York, New York 10021, USA
    Am J Cardiol 92:1214-7. 2003
    ....
  79. ncbi request reprint New-device angioplasty in women: clinical outcome and predictors in a 7,372-patient registry
    Alexandra J Lansky
    Cardiac Catheterization Laboratory and the Women s Cardiac Health Initiative, Lenox Hill Hospital, New York City, NY 10022, USA
    Epidemiology 13:S46-51. 2002
    ..To gain insight into the outcome of women after new-device angioplasty, we reviewed the early and late clinical outcome of 7,372 patients undergoing new-device angioplasty between 1991 and 1996 at the Washington Hospital Center...
  80. ncbi request reprint Gamma radiation for in-stent restenosis: effect of lesion length on angiographic and clinical outcomes
    Roxana Mehran
    Cardiovascular Research Foundation, Lenox Hill Heart and Vascular Institute, New York, New York 10022, USA
    Catheter Cardiovasc Interv 61:354-9. 2004
    ..Lesion length remains a powerful predictor of recurrent ISR and clinical events after treatment of ISR even with gamma-RT...
  81. ncbi request reprint Frequency, correlates, and clinical implications of myocardial perfusion after primary angioplasty and stenting, with and without glycoprotein IIb/IIIa inhibition, in acute myocardial infarction
    Costantino O Costantini
    Cardiovascular Research Foundation and Lenox Hill Hospital, New York, New York, USA
    J Am Coll Cardiol 44:305-12. 2004
    ..We sought to determine the prognostic importance of myocardial reperfusion after various contemporary interventional strategies in patients with acute myocardial infarction (AMI)...
  82. ncbi request reprint Estrogen-eluting, phosphorylcholine-coated stent implantation is associated with reduced neointimal formation but no delay in vascular repair in a porcine coronary model
    Gishel New
    Lenox Hill Heart and Vascular Institute and Cardiovascular Research Foundation, New York, New York 10021, USA
    Catheter Cardiovasc Interv 57:266-71. 2002
    ..Estrogen-coated stents may have a potential benefit in the prevention and treatment of in-stent restenosis...
  83. doi request reprint Necrotic core and its ratio to dense calcium are predictors of high-risk non-ST-elevation acute coronary syndrome
    Eduardo Missel
    Cardiovascular Research Foundation, Columbia University Medical Center, New York, NY, USA
    Am J Cardiol 101:573-8. 2008
    ..01) than patients with no predictors. In conclusion, VH-IVUS analysis showed that the percentage of NC and its ratio to DC in diseased coronary segments are positively associated with a high-risk ACS presentation...
  84. ncbi request reprint Serial intravascular ultrasound analysis of bifurcation lesions treated using the novel self-expanding sideguard side branch stent
    Hiroshi Doi
    Cardiovascular Research Foundation and Columbia University Medical Center, New York, New York, USA
    Am J Cardiol 104:1216-21. 2009
    ..35). In conclusion, serial IVUS analyses of the self-expanding bare metal Sideguard stent indicate preserved SB ostial lumen dimensions at follow-up due to additional increases in stent area that more than compensated for IH...
  85. ncbi request reprint Angiographic results of the first human experience with everolimus-eluting stents for the treatment of coronary lesions (the FUTURE I trial)
    Ricardo A Costa
    Cardiovascular Research Foundation and Columbia University Medical Center, New York, New York 10022, USA
    Am J Cardiol 95:113-6. 2005
    ..There was 1 in-stent and 1 in-segment (proximal edge) restenosis in the metallic stent group. There was no stent thrombosis or aneurysm formation at follow-up in either group...
  86. pmc Late incomplete lesion coverage following Cypher stent deployment for diffuse right coronary artery stenosis
    A Halkin
    Cardiovascular Research Foundation and Lenox Hill Heart and Vascular Institute, New York, New York 10022, USA
    Heart 90:e45. 2004
    ..A case of stent fracture following percutaneous coronary intervention in which this strategy was used is reported...
  87. ncbi request reprint Brachytherapy for in-stent restenosis through the internal mammary artery
    Y Kobayashi
    Lenox Hill Heart and Vascular Institute, New York, New York, USA
    Catheter Cardiovasc Interv 53:530-4. 2001
    ..After angioplasty, catheter-based gamma radiation was performed. There was no delivery failure of the radiation system. All cases had angiographic success and no procedural or in-hospital complications...
  88. ncbi request reprint Intra-arterial reteplase for the treatment of acute limb ischemia
    J R Laird
    Cardiovascular Research Foundation, 110 Irving Street N W, Suite 4B 1, Washington, D C 20010, USA
    J Invasive Cardiol 11:757-62. 1999
    ..We report two cases of successful treatment of acute, limb threatening ischemia with intra-arterial Reteplase therapy...
  89. ncbi request reprint One-year clinical outcome after minimally invasive direct coronary artery bypass
    R Mehran
    Cardiovascular Research Foundation, New York, NY 10022, USA
    Circulation 102:2799-802. 2000
    ..Minimally invasive coronary artery bypass (MIDCAB) is a new surgical technique by which the left internal mammary artery is anastomosed under direct visualization to the left anterior descending artery without cardiopulmonary bypass...
  90. ncbi request reprint Subarachnoidal hemorrhage following carotid stenting with the distal-balloon protection
    N Al-Mubarak
    The Lenox Hill Heart and Vascular Institute of New York, New York, NY, USA
    Catheter Cardiovasc Interv 54:521-3. 2001
    ..Head CT scan showed massive subarachnoidal hemorrhage contralateral to the stented side and a secondary intracerebral hemorrhage. Despite immediate successful blood pressure control, his condition deteriorated and he died 2 days later...
  91. ncbi request reprint Echocardiographic assessment of pressure volume relations in heart failure and valvular heart disease: using imaging to understand physiology
    P Green
    Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, NY 10034, USA
    Minerva Cardioangiol 59:375-89. 2011
    ..This review explores the physiologic background, basic methodology, and recent and potential future applications of noninvasive PV analysis...
  92. ncbi request reprint Effect of short pulsed nonablative infrared laser irradiation on vascular cells in vitro and neointimal hyperplasia in a rabbit balloon injury model
    N Kipshidze
    Lenox Hill Heart and Vascular Institute of New York and Cardiovascular Research Foundation, New York, NY, USA
    Circulation 104:1850-5. 2001
    ..Neointimal hyperplasia after PTCA is an important component of restenosis...
  93. ncbi request reprint Electromagnetic guidance for catheter-based transendocardial injection: a platform for intramyocardial angiogenesis therapy. Results in normal and ischemic porcine models
    R Kornowski
    Cardiovascular Research Foundation, Washington Hospital Center, Washington, DC 20010, USA
    J Am Coll Cardiol 35:1031-9. 2000
    ..To test the feasibility of myocardial angiogenic gene expression using a novel catheter-based transendocardial injection system...
  94. ncbi request reprint Vascular complications after percutaneous coronary interventions following hemostasis with manual compression versus arteriotomy closure devices
    G Dangas
    Cardiovascular Research Foundation, Lenox Hill Heart and Vascular Institute, New York, New York, USA
    J Am Coll Cardiol 38:638-41. 2001
    ..5 vs. 1.5%, p = 0.03). CONCLUSIONS: In this early experience with ACD after PCI, their use was associated with higher vascular complication rates than hemostasis with manual compression...
  95. ncbi request reprint Local delivery of c-myc neutrally charged antisense oligonucleotides with transport catheter inhibits myointimal hyperplasia and positively affects vascular remodeling in the rabbit balloon injury model
    N Kipshidze
    Lenox Hill Heart and Vascular Institute of New York and Cardiovascular Research Foundation, New York, New York 10021, USA
    Catheter Cardiovasc Interv 54:247-56. 2001
    ..82 +/- 0.32 mm(2) in the control and antisense delivery groups, respectively (P < 0.05). We conclude that local delivery of Resten-NG inhibited myointimal hyperplasia after PTCA in cholesterol-fed rabbits for up to 60 days...
  96. ncbi request reprint Quantitative assessment of angiographic restenosis after sirolimus-eluting stent implantation in native coronary arteries
    Jeffrey J Popma
    Department of Internal Medicine, Cardiovascular Division, Brigham and Women s Hospital, 75 Francis St, Boston, Mass 02115, USA
    Circulation 110:3773-80. 2004
    ..Sirolimus-eluting stents (SESs) reduce angiographic restenosis in patients with focal, native coronary artery stenoses. This study evaluated the usefulness of SESs in complex native-vessel lesions at high risk for restenosis...
  97. ncbi request reprint Randomized trial of a distal embolic protection device during percutaneous intervention of saphenous vein aorto-coronary bypass grafts
    Donald S Baim
    Division of Cardiovascular Diseases, Brigham and Women s Hospital, Boston, Mass 02115, USA
    Circulation 105:1285-90. 2002
    ..We report the first multicenter randomized trial to evaluate use of a distal embolic protection device during stenting of such lesions...
  98. doi request reprint Evolving strategies for the treatment of valvular heart disease: Preclinical and clinical pathways for percutaneous aortic valve replacement
    James I Fann
    Catheter Cardiovasc Interv 71:434-40. 2008
    ..g., conventional aortic valve replacement, best medical management, and/or balloon valvuloplasty...
  99. ncbi request reprint Vascular response to sirolimus-eluting stents delivered with a nonaggressive implantation technique: comparison of intravascular ultrasound results from the multicenter, randomized E-SIRIUS, and SIRIUS trials
    Rainer Hoffmann
    Medical Clinic I, University Hospital Aachen, Aachen, Germany
    Catheter Cardiovasc Interv 66:499-506. 2005
    ....
  100. ncbi request reprint Predictors of edge stenosis following sirolimus-eluting stent deployment (a quantitative intravascular ultrasound analysis from the SIRIUS trial)
    Ryota Sakurai
    Center for Research in Cardiovascular Interventions, Stanford University Medical Center, Stanford, California, USA
    Am J Cardiol 96:1251-3. 2005
    ..Thus, full lesion coverage and matching the stented segment properly to the adjacent segment using intravascular ultrasound guidance may improve sirolimus-eluting stent implantation efficacy further...
  101. ncbi request reprint Impact of intravascular ultrasound lesion characteristics on neointimal hyperplasia following sirolimus-eluting stent implantation
    Hideaki Kaneda
    The Center for Research in Cardiovascular Interventions, Stanford University, Stanford, California, USA
    Am J Cardiol 96:1237-41. 2005
    ..In patients who have coronary artery disease, sirolimus-eluting stents continue to demonstrate striking suppression of neointimal proliferation, irrespective of lesion characteristics previously associated with greater restenotic risk...