Ning Zhang

Summary

Affiliation: Caliper Life Sciences
Country: USA

Publications

  1. pmc Imaging pulmonary NF-kappaB activation and therapeutic effects of MLN120B and TDZD-8
    Dan Ansaldi
    Caliper Life Sciences, Alameda, California, United States of America
    PLoS ONE 6:e25093. 2011
  2. doi request reprint A spontaneous acinar cell carcinoma model for monitoring progression of pancreatic lesions and response to treatment through noninvasive bioluminescence imaging
    Ning Zhang
    Caliper Life Sciences, Alameda, CA 94501, USA
    Clin Cancer Res 15:4915-24. 2009
  3. ncbi request reprint Serum amyloid A-luciferase transgenic mice: response to sepsis, acute arthritis, and contact hypersensitivity and the effects of proteasome inhibition
    Ning Zhang
    Xenogen, Alameda, CA 94501, USA
    J Immunol 174:8125-34. 2005
  4. ncbi request reprint Tracking angiogenesis induced by skin wounding and contact hypersensitivity using a Vegfr2-luciferase transgenic mouse
    Ning Zhang
    Xenogen Corporation, 860 Atlantic Ave, Alameda, CA 94501
    Blood 103:617-26. 2004
  5. ncbi request reprint NF-kappaB and not the MAPK signaling pathway regulates GADD45beta expression during acute inflammation
    Ning Zhang
    Xenogen Corporation, Alameda, California 94501, USA
    J Biol Chem 280:21400-8. 2005
  6. pmc Monitoring bacterial burden, inflammation and bone damage longitudinally using optical and μCT imaging in an orthopaedic implant infection in mice
    Jared A Niska
    Orthopaedic Hospital Research Center, Orthopaedic Hospital Department of Orthopaedic Surgery, David Geffen School of Medicine at University of California Los Angeles UCLA, Los Angeles, California, USA
    PLoS ONE 7:e47397. 2012
  7. doi request reprint Enhanced detection of myeloperoxidase activity in deep tissues through luminescent excitation of near-infrared nanoparticles
    Ning Zhang
    Caliper Life Sciences, Alameda, California, USA
    Nat Med 19:500-5. 2013
  8. ncbi request reprint An inducible nitric oxide synthase-luciferase reporter system for in vivo testing of anti-inflammatory compounds in transgenic mice
    Ning Zhang
    Xenogen Corporation, Alameda, CA 94501, USA
    J Immunol 170:6307-19. 2003

Collaborators

  • Jae Beom Kim
  • Lloyd S Miller
  • Arun Prakash
  • Jared A Niska
  • Ed Lim
  • Kevin P Francis
  • Dan Ansaldi
  • Brad W Rice
  • Jeffrey A Meganck
  • Nicholas M Bernthal
  • Jonathan R Pribaz
  • Romela Irene Ramos
  • Jonathan H Shahbazian
  • Ali Akin
  • Rajendra Singh
  • Fabio Stellari
  • Mark Roskey
  • Eldad A Hod

Detail Information

Publications8

  1. pmc Imaging pulmonary NF-kappaB activation and therapeutic effects of MLN120B and TDZD-8
    Dan Ansaldi
    Caliper Life Sciences, Alameda, California, United States of America
    PLoS ONE 6:e25093. 2011
    ..This approach will potentiate further studies on NF-κB regulation under various inflammatory conditions...
  2. doi request reprint A spontaneous acinar cell carcinoma model for monitoring progression of pancreatic lesions and response to treatment through noninvasive bioluminescence imaging
    Ning Zhang
    Caliper Life Sciences, Alameda, CA 94501, USA
    Clin Cancer Res 15:4915-24. 2009
    ..We have generated an EL1-luc/TAg transgenic mouse model that develops spontaneous and bioluminescent acinar cell carcinomas. We applied this model to noninvasively monitor tumor development and drug response...
  3. ncbi request reprint Serum amyloid A-luciferase transgenic mice: response to sepsis, acute arthritis, and contact hypersensitivity and the effects of proteasome inhibition
    Ning Zhang
    Xenogen, Alameda, CA 94501, USA
    J Immunol 174:8125-34. 2005
    ..These results suggest that both local and systemic induction of A-SAA occur during inflammation and may contribute to the pathogenesis of chronic inflammatory diseases associated with amyloid deposition...
  4. ncbi request reprint Tracking angiogenesis induced by skin wounding and contact hypersensitivity using a Vegfr2-luciferase transgenic mouse
    Ning Zhang
    Xenogen Corporation, 860 Atlantic Ave, Alameda, CA 94501
    Blood 103:617-26. 2004
    ..The Vegfr2-luc model will be valuable in monitoring the ability of drugs to affect angiogenesis in vivo...
  5. ncbi request reprint NF-kappaB and not the MAPK signaling pathway regulates GADD45beta expression during acute inflammation
    Ning Zhang
    Xenogen Corporation, Alameda, California 94501, USA
    J Biol Chem 280:21400-8. 2005
    ..Thus, NF-kappaB signaling involves induction of GADD45beta expression, which supports the proposed role of GADD45beta in protecting cells against DNA damaged under various stress conditions...
  6. pmc Monitoring bacterial burden, inflammation and bone damage longitudinally using optical and μCT imaging in an orthopaedic implant infection in mice
    Jared A Niska
    Orthopaedic Hospital Research Center, Orthopaedic Hospital Department of Orthopaedic Surgery, David Geffen School of Medicine at University of California Los Angeles UCLA, Los Angeles, California, USA
    PLoS ONE 7:e47397. 2012
    ..These infections are characterized by the formation of persistent bacterial biofilms on the implanted materials, causing inflammation, periprosthetic osteolysis, osteomyelitis, and bone damage, resulting in implant loosening and failure...
  7. doi request reprint Enhanced detection of myeloperoxidase activity in deep tissues through luminescent excitation of near-infrared nanoparticles
    Ning Zhang
    Caliper Life Sciences, Alameda, California, USA
    Nat Med 19:500-5. 2013
    ..We developed a sensitive MPO detection methodology that provides a means for visualizing and quantifying oxidative stress in deep tissue. This method is amenable to rapid evaluation of anti-inflammatory agents in animal models...
  8. ncbi request reprint An inducible nitric oxide synthase-luciferase reporter system for in vivo testing of anti-inflammatory compounds in transgenic mice
    Ning Zhang
    Xenogen Corporation, Alameda, CA 94501, USA
    J Immunol 170:6307-19. 2003
    ..The establishment of the iNos-luc transgenic model provides a valuable tool for studying processes in which the iNOS gene is induced and for screening anti-inflammatory compounds in vivo...