BENEDICT B YASPELKIS
Affiliation: California State University
Yaspelkis B, Singh M, Krisan A, Collins D, Kwong C, Bernard J, et al
. Chronic leptin treatment enhances insulin-stimulated glucose disposal in skeletal muscle of high-fat fed rodents. Life Sci. 2004;74:1801-16 pubmed
Yaspelkis B, Kvasha I, Lessard S, Rivas D, Hawley J. Aerobic training reverses high-fat diet-induced pro-inflammatory signalling in rat skeletal muscle. Eur J Appl Physiol. 2010;110:779-88 pubmed publisher
..Additionally, the reduction in IKK?/? serine phosphorylation in HFX may have contributed to decreasing IRS-1 serine phosphorylation, and in turn, promoted the normalization of insulin-stimulated activation of PI-3 kinase. ..
Yaspelkis B, Davis J, Saberi M, Smith T, Jazayeri R, Singh M, et al
. Leptin administration improves skeletal muscle insulin responsiveness in diet-induced insulin-resistant rats. Am J Physiol Endocrinol Metab. 2001;280:E130-42 pubmed
..The findings suggest that chronic leptin administration reversed a high-fat diet-induced insulin-resistant state, without compromising insulin secretion...
Yaspelkis B, Lessard S, Reeder D, Limon J, Saito M, Rivas D, et al
. Exercise reverses high-fat diet-induced impairments on compartmentalization and activation of components of the insulin-signaling cascade in skeletal muscle. Am J Physiol Endocrinol Metab. 2007;293:E941-9 pubmed
..Our findings indicate that chronic exercise training, but not rosiglitazone, reverses high-fat diet induced impairments in compartmentalization and activation of components of the insulin-signaling cascade in skeletal muscle. ..
Yaspelkis B, Kvasha I, Figueroa T. High-fat feeding increases insulin receptor and IRS-1 coimmunoprecipitation with SOCS-3, IKKalpha/beta phosphorylation and decreases PI-3 kinase activity in muscle. Am J Physiol Regul Integr Comp Physiol. 2009;296:R1709-15 pubmed publisher