Joel Smith

Summary

Affiliation: California Institute of Technology
Country: USA

Publications

  1. pmc The genome of the sea urchin Strongylocentrotus purpuratus
    Erica Sodergren
    Science 314:941-52. 2006
  2. ncbi request reprint A gene regulatory network subcircuit drives a dynamic pattern of gene expression
    Joel Smith
    Division of Biology, 156 29, California Institute of Technology, Pasadena, CA 91125, USA
    Science 318:794-7. 2007
  3. pmc Regulative recovery in the sea urchin embryo and the stabilizing role of fail-safe gene network wiring
    Joel Smith
    Division of Biology 156 29, California Institute of Technology, Pasadena, CA 91125, USA
    Proc Natl Acad Sci U S A 106:18291-6. 2009
  4. pmc A spatially dynamic cohort of regulatory genes in the endomesodermal gene network of the sea urchin embryo
    Joel Smith
    Division of Biology 156 29, California Institute of Technology, Pasadena, CA 91125, USA
    Dev Biol 313:863-75. 2008
  5. doi request reprint A protocol describing the principles of cis-regulatory analysis in the sea urchin
    Joel Smith
    Division of Biology, California Institute of Technology, 1200 E California Boulevard, Pasadena, California 91125, USA
    Nat Protoc 3:710-8. 2008
  6. doi request reprint A new method, using cis-regulatory control, for blocking embryonic gene expression
    Joel Smith
    Division of Biology 156 29, California Institute of Technology, Pasadena, CA 91125, USA
    Dev Biol 318:360-5. 2008
  7. pmc Gene regulatory network subcircuit controlling a dynamic spatial pattern of signaling in the sea urchin embryo
    Joel Smith
    Division of Biology 156 29, California Institute of Technology, Pasadena, CA 91125, USA
    Proc Natl Acad Sci U S A 105:20089-94. 2008
  8. pmc Notch and Nodal control forkhead factor expression in the specification of multipotent progenitors in sea urchin
    Stefan C Materna
    Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Development 140:1796-806. 2013

Collaborators

Detail Information

Publications8

  1. pmc The genome of the sea urchin Strongylocentrotus purpuratus
    Erica Sodergren
    Science 314:941-52. 2006
    ..This echinoderm genome provides an evolutionary outgroup for the chordates and yields insights into the evolution of deuterostomes...
  2. ncbi request reprint A gene regulatory network subcircuit drives a dynamic pattern of gene expression
    Joel Smith
    Division of Biology, 156 29, California Institute of Technology, Pasadena, CA 91125, USA
    Science 318:794-7. 2007
    ..GRN circuitry thus controls not only static spatial assignment in development but also dynamic regulatory patterning...
  3. pmc Regulative recovery in the sea urchin embryo and the stabilizing role of fail-safe gene network wiring
    Joel Smith
    Division of Biology 156 29, California Institute of Technology, Pasadena, CA 91125, USA
    Proc Natl Acad Sci U S A 106:18291-6. 2009
    ..Genomically encoded backup control circuitry thus provides the mechanism underlying a specific example of the regulative development for which the sea urchin embryo has long been famous...
  4. pmc A spatially dynamic cohort of regulatory genes in the endomesodermal gene network of the sea urchin embryo
    Joel Smith
    Division of Biology 156 29, California Institute of Technology, Pasadena, CA 91125, USA
    Dev Biol 313:863-75. 2008
    ....
  5. doi request reprint A protocol describing the principles of cis-regulatory analysis in the sea urchin
    Joel Smith
    Division of Biology, California Institute of Technology, 1200 E California Boulevard, Pasadena, California 91125, USA
    Nat Protoc 3:710-8. 2008
    ..Although the expected time line varies greatly with the depth of information required, results may be obtained in as little as 4-6 months, but more detailed analyses will require several years to complete...
  6. doi request reprint A new method, using cis-regulatory control, for blocking embryonic gene expression
    Joel Smith
    Division of Biology 156 29, California Institute of Technology, Pasadena, CA 91125, USA
    Dev Biol 318:360-5. 2008
    ..This method thus provides the opportunity to study regulatory requirements of skeletogenesis after ingression, and may be similarly useful in many other developmental contexts...
  7. pmc Gene regulatory network subcircuit controlling a dynamic spatial pattern of signaling in the sea urchin embryo
    Joel Smith
    Division of Biology 156 29, California Institute of Technology, Pasadena, CA 91125, USA
    Proc Natl Acad Sci U S A 105:20089-94. 2008
    ..Thus the specific cis-regulatory linkages of the gene regulatory network encode the coordinated spatial expression of Wnt and Notch signaling as they sweep outward across the vegetal plate of the embryo...
  8. pmc Notch and Nodal control forkhead factor expression in the specification of multipotent progenitors in sea urchin
    Stefan C Materna
    Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Development 140:1796-806. 2013
    ..Our experiments place foxY at the top of the regulatory hierarchy underlying the specification of a cell type that maintains developmental potency...