Research Topics
| Erich M SchwarzSummaryAffiliation: California Institute of Technology Country: USA Publications
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Detail Information
Publications
WormBase: better software, richer contentErich M Schwarz
Division of Biology, 156 29 California Institute of Technology, Pasadena, CA, 91125, USA
Nucleic Acids Res 34:D475-8. 2006....
Scaffolding a Caenorhabditis nematode genome with RNA-seqAli Mortazavi
Division of Biology, California Institute of Technology, Pasadena, California 91125, USA
Genome Res 20:1740-7. 2010..elegans that are likely to encode regulatory sequences or previously unknown ncRNAs. Genomic and cDNA sequencing followed by joint assembly is a rapid and useful strategy for biological analysis...
WormBase 2012: more genomes, more data, new websiteKaren Yook
Division of Biology 156 29, California Institute of Technology, Pasadena, CA 91125, USA
Nucleic Acids Res 40:D735-41. 2012..We report on the growth of our database and on our work in keeping pace with the growing demand for data, efforts to anticipate the requirements of users and new collaborations with the larger science community...
Functional transcriptomics of a migrating cell in Caenorhabditis elegansErich M Schwarz
Division of Biology and Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA 91125, USA
Proc Natl Acad Sci U S A 109:16246-51. 2012..Our results provide an extensive catalog of genes that act in a migrating cell, identify unique molecular functions involved in nematode cell migration, and suggest similar functions in humans...
Searching WormBase for information about Caenorhabditis elegansErich M Schwarz
California Institute of Technology, Pasadena, California, USA
Curr Protoc Bioinformatics . 2006..The WormBase developers group actively invites suggestions for improvements from the database users. WormBase's source code and underlying database are freely available for local installation and modification...
Multigenome DNA sequence conservation identifies Hox cis-regulatory elementsSteven G Kuntz
Division of Biology, California Institute of Technology, Pasadena, California 91125, USA
Genome Res 18:1955-68. 2008..Our findings suggest that ungapped sequence comparisons can predict regulatory elements genome-wide...
Identification of DVA interneuron regulatory sequences in Caenorhabditis elegansCarmie Puckett Robinson
Division of Biology and Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA, USA
PLoS ONE 8:e54971. 2013..The existence of a complete genome sequence for C. elegans and draft genomes of other nematodes let us use comparative genomics to identify regulatory sequences directing expression in the DVA interneuron...
WormBase 2007Anthony Rogers
Sanger Institute, Wellcome Trust Genome Campus Hinxton, Cambridgeshire CB10 1SA, UK
Nucleic Acids Res 36:D612-7. 2008..Improved search and display tools, wider cross-species comparisons and extended ontologies are some of the features that will help scientists extend their research and take advantage of other nematode species genome sequences...
WormBase: new content and better accessTamberlyn Bieri
Genome Sequencing Center, Washington University School of Medicine, St Louis, MO 63108, USA
Nucleic Acids Res 35:D506-10. 2007..Access to and searching WormBase has become more dependable and flexible via multiple mirror sites and indexing through Google...
WormBase: a comprehensive data resource for Caenorhabditis biology and genomicsNansheng Chen
Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
Nucleic Acids Res 33:D383-9. 2005..Internally, we have restructured the database models to rationalize the representation of genes and to prepare the system to accept the genome sequences of three additional Caenorhabditis species over the coming year...
WormBase: a multi-species resource for nematode biology and genomicsTodd W Harris
Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
Nucleic Acids Res 32:D411-7. 2004..These advances continue to increase the utility of WormBase for C.elegans researchers, as well as for those researchers exploring problems in functional and comparative genomics in the context of a powerful genetic system...
Genetic interactions among cortical malformation genes that influence susceptibility to convulsions in C. elegansCody J Locke
Department of Biological Sciences, The University of Alabama, Box 870344, Tuscaloosa, AL 35487 0344, USA
Brain Res 1120:23-34. 2006..Thus, interactions among gene products with LIS-1 may mediate intrinsic thresholds of neuronal synchrony...
Transducing touch in Caenorhabditis elegansMiriam B Goodman
Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, California 94305, USA
Annu Rev Physiol 65:429-52. 2003..elegans, with an emphasis on insights into their function derived from mutation. We also review the neuronal cell types in which these channels might be expressed and mediate mechanotransduction...
