Paul W K Rothemund
Affiliation: California Institute of Technology
- Design and characterization of programmable DNA nanotubesPaul W K Rothemund
Department of Computer Science, California Institute of Technology, Pasadena, California 91125, USA
J Am Chem Soc 126:16344-52. 2004..Supported by these results, nanotube structure is explained by a simple model based on the geometry and energetics of B-form DNA...
- Folding DNA to create nanoscale shapes and patternsPaul W K Rothemund
Departments of Computer Science and Computation and Neural Systems, California Institute of Technology, Pasadena, California 91125, USA
Nature 440:297-302. 2006..Finally, individual DNA structures can be programmed to form larger assemblies, including extended periodic lattices and a hexamer of triangles (which constitutes a 30-megadalton molecular complex)...
- Two computational primitives for algorithmic self-assembly: copying and countingRobert D Barish
Department of Computer Science, California Institute of Technology and Computation and Neural Systems, Pasadena, CA 91125, USA
Nano Lett 5:2586-92. 2005..A subset of the tiles for counting form information-bearing DNA tubes that copy bit strings from layer to layer along their length...
- An information-bearing seed for nucleating algorithmic self-assemblyRobert D Barish
California Institute of Technology, Pasadena, CA 91125, USA
Proc Natl Acad Sci U S A 106:6054-9. 2009..In sum, this work demonstrates how DNA origami seeds enable the easy, high-yield, low-error-rate growth of algorithmic crystals as a route toward programmable bottom-up fabrication...
- Self-assembly of carbon nanotubes into two-dimensional geometries using DNA origami templatesHareem T Maune
California Institute of Technology, Pasadena, California 91125, USA
Nat Nanotechnol 5:61-6. 2010..In such organizations of electronic components, DNA origami serves as a programmable nanobreadboard; thus, DNA origami may allow the rapid prototyping of complex nanotube-based structures...
- Algorithmic self-assembly of DNA Sierpinski trianglesPaul W K Rothemund
Computation and Neural Systems, California Institute of Technology, Pasadena, USA
PLoS Biol 2:e424. 2004..This shows that engineered DNA self-assembly can be treated as a Turing-universal biomolecular system, capable of implementing any desired algorithm for computation or construction tasks...
- Programmable molecular recognition based on the geometry of DNA nanostructuresSungwook Woo
Department of Bioengineering, California Institute of Technology, Pasadena, California 91125, USA
Nat Chem 3:620-7. 2011..This work, which demonstrates how a single attractive interaction can be developed to create diverse bonds, may guide strategies for molecular recognition in systems beyond DNA nanostructures...
- An autonomous polymerization motor powered by DNA hybridizationSuvir Venkataraman
Nat Nanotechnol 2:490-4. 2007..DNA strands are propelled processively at the living end of the growing polymers, demonstrating autonomous locomotion powered by the free energy of DNA hybridization...
- Sturdier DNA nanotubes via ligationPaul W K Rothemund
Department of Physics, University of California, Santa Barbara, 93106, USA
Nano Lett 6:1379-83. 2006..Ligated DNA nanotubes are thus physically and chemically sturdy enough to withstand the manipulations necessary for many technological applications...
- Solution of a 20-variable 3-SAT problem on a DNA computerRavinderjit S Braich
University of Southern California, Laboratory for Molecular Science, Los Angeles, CA 90089-1340, USA
Science 296:499-502. 2002..This computational problem may be the largest yet solved by nonelectronic means. Problems of this size appear to be beyond the normal range of unaided human computation...