Research Topics
| Paul W K RothemundSummaryAffiliation: California Institute of Technology Country: USA Publications
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Detail Information
Publications
Design and characterization of programmable DNA nanotubesPaul W K Rothemund
Department of Computer Science, California Institute of Technology, Pasadena, California 91125, USA
J Am Chem Soc 126:16344-52. 2004..Supported by these results, nanotube structure is explained by a simple model based on the geometry and energetics of B-form DNA...
Folding DNA to create nanoscale shapes and patternsPaul W K Rothemund
Departments of Computer Science and Computation and Neural Systems, California Institute of Technology, Pasadena, California 91125, USA
Nature 440:297-302. 2006..Finally, individual DNA structures can be programmed to form larger assemblies, including extended periodic lattices and a hexamer of triangles (which constitutes a 30-megadalton molecular complex)...
Two computational primitives for algorithmic self-assembly: copying and countingRobert D Barish
Department of Computer Science, California Institute of Technology and Computation and Neural Systems, Pasadena, CA 91125, USA
Nano Lett 5:2586-92. 2005..A subset of the tiles for counting form information-bearing DNA tubes that copy bit strings from layer to layer along their length...
An information-bearing seed for nucleating algorithmic self-assemblyRobert D Barish
California Institute of Technology, Pasadena, CA 91125, USA
Proc Natl Acad Sci U S A 106:6054-9. 2009..In sum, this work demonstrates how DNA origami seeds enable the easy, high-yield, low-error-rate growth of algorithmic crystals as a route toward programmable bottom-up fabrication...
Self-assembly of carbon nanotubes into two-dimensional geometries using DNA origami templatesHareem T Maune
California Institute of Technology, Pasadena, California 91125, USA
Nat Nanotechnol 5:61-6. 2010..In such organizations of electronic components, DNA origami serves as a programmable nanobreadboard; thus, DNA origami may allow the rapid prototyping of complex nanotube-based structures...
Algorithmic self-assembly of DNA Sierpinski trianglesPaul W K Rothemund
Computation and Neural Systems, California Institute of Technology, Pasadena, USA
PLoS Biol 2:e424. 2004..This shows that engineered DNA self-assembly can be treated as a Turing-universal biomolecular system, capable of implementing any desired algorithm for computation or construction tasks...
Programmable molecular recognition based on the geometry of DNA nanostructuresSungwook Woo
Department of Bioengineering, California Institute of Technology, Pasadena, California 91125, USA
Nat Chem 3:620-7. 2011..This work, which demonstrates how a single attractive interaction can be developed to create diverse bonds, may guide strategies for molecular recognition in systems beyond DNA nanostructures...
An autonomous polymerization motor powered by DNA hybridizationSuvir Venkataraman
Nat Nanotechnol 2:490-4. 2007..DNA strands are propelled processively at the living end of the growing polymers, demonstrating autonomous locomotion powered by the free energy of DNA hybridization...
Sturdier DNA nanotubes via ligationPaul W K Rothemund
Department of Physics, University of California, Santa Barbara, 93106, USA
Nano Lett 6:1379-83. 2006..Ligated DNA nanotubes are thus physically and chemically sturdy enough to withstand the manipulations necessary for many technological applications...
Solution of a 20-variable 3-SAT problem on a DNA computerRavinderjit S Braich
University of Southern California, Laboratory for Molecular Science, Los Angeles, CA 90089-1340, USA
Science 296:499-502. 2002..This computational problem may be the largest yet solved by nonelectronic means. Problems of this size appear to be beyond the normal range of unaided human computation...
