P Reynolds

..This large cohort study has followed female professional school employees for cancer incidence since 1995 and has collected extensive information on breast cancer risk factors...

..Motor vehicle emissions are a major source of air pollution in California. Past studies have suggested that traffic-related exposures can increase the risk of childhood cancer, particularly leukemia...

..These results suggest that the opportunity for emotional expression may help improve survival among patients with invasive breast cancer...

..This study describes the prevalence and patterns of environmental tobacco smoke (ETS) exposure in a large, well-defined cohort of professional, female school employees in California...

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..Periodic concerns about excesses of cancer among teachers in California schools prompted our examination of cancer incidence in California school employees...

..Associations with the diagnosis address or with more direct exposure measures may differ from those reported here...

..The distribution of agricultural pesticide use and number of potentially exposed children suggests that pesticide use density would be of value for a study of childhood cancer...

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..Although most studies have low power to detect workplace risk estimates in the modest range suggested by the larger studies, risk estimates tend to be consistent with those for exposure from a smoking spouse...

..These data may be helpful in establishing a baseline for PBDE body burdens to gauge changes over time as a result of restrictions in the use of PBDE formulations...

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..Our analyses suggest that breast cancer incidence is not elevated in areas of recent, high agricultural pesticide use in California...

..These analyses were designed to describe characteristics associated with active and passive smoking in a large cohort of women in order to identify possible confounders of the relationship between smoking exposures and breast cancer risk...

..Our objective was to evaluate the breast cancer risk associated with body burden levels of polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs)...

..This study describes and evaluates characteristics associated with residential mobility in a sub-sample of the California Teachers Study (CTS) cohort...

..However, the health impacts of long-term exposure to specific constituents of PM(2.5) (PM with aerodynamic diameter < or = 2.5 microm) have not been explored...

..The results from this study provide no evidence that California women living in areas of recent, high agricultural pesticide use experience higher rates of breast cancer...

..This study evaluated whether the rates of lymphoproliferative malignancies among children are elevated in areas of intensive agricultural pesticide use in the state of California in the United States...

..This study describes geographic breast cancer incidence patterns within California and evaluates the degree to which socioeconomic status (SES) and urbanization explain the regional variability...

..With the exception of documented correlations with certain congenital anomalies, the etiology of hepatoblastoma remains largely unknown...

..High birthweight is a potential risk factor for childhood brain tumours, particularly astrocytomas. We investigated several birth characteristics in relationship to brain cancers in young children...

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..Future exposure assessment studies should target the highest traffic density areas, and health studies should consider the differences by income and race or ethnicity during design...

..25, 95% CI: 1.04, 1.52), although this odds ratio was somewhat reduced when adjusted for other factors. No strong relations were observed for birth weight and ALL or ANLL...

..48; 95% CI, 1.03-2.13) in block groups with the highest use of propargite, although we saw no dose-response trend with increasing exposure categories. Results were unchanged by further adjustment for socioeconomic status and urbanization...

..To date, literature addressing this question has been mixed, and the question has seldom been examined in large prospective study designs...

..CONCLUSIONS: Disease registries should modernize their infrastructure to complement GIS technologies. Epidemiologists should understand GIS data limitations and consider potential biases introduced by incomplete or inaccurate geocoding...

..The State of California maintains a comprehensive Pesticide Use Reporting Database (CPUR). The California Department of Water Resources (CDWR) maps all crops in agricultural counties in California about once every 5 years...

..One potential explanation for this inconsistency is that hormone therapy, which is associated with lower colon cancer risk, acts as a modifier of the physical activity/colon cancer relationship...

..Long-term physical activity may affect breast cancer risk. Few prospective studies have evaluated in situ or invasive breast cancer risk, or breast cancer receptor subtypes, in relation to long-term activity...

..Clear dose-response relationships consistent with a causal association were observed between exposure to secondhand smoke from spousal, workplace and social sources and the development of lung cancer among never smokers...

..To evaluate the reproductive and lifestyle correlates of a surgically confirmed diagnosis of endometriosis or adenomyosis in a large prospective cohort...

..The role of pesticide exposures in the etiology of human cancer is outlined by anatomical site and recent development in exposure assessment and molecular epidemiology are summarized and evaluated...

..Here, we compare levels of pesticides and other compounds in dust from household vacuums to that collected using the HVS3...

..Overall, our results show no convincing associations between dietary patterns and ovarian cancer risk...

..Several large prospective studies, which eliminate recall bias, did not detect associations, but this relationship continues to be debated...

..Exposures to carcinogenic compounds from vehicle exhaust may increase childhood leukemia risk, and the timing of this exposure may be important...

..39, 95% CI: 0.22, 0.69). These data suggest that etiologic factors associated with the prenatal and perinatal periods may be specific to age at neuroblastoma diagnosis...

..Self-reported indicators of residential proximity to high traffic volume were, however, associated with GIS traffic density measures...

..0% for 560 enrolled birth certificate controls), using birth records to recruit controls appears to provide a representative sample of children and an opportunity to assess the representativeness of controls...

..The combination of self-reports and secondary medical records provides more accurate and complete morbidity data than does use of either source alone...

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..We investigated the association of NSAID use with risk of breast cancer in the California Teachers Study cohort, with special attention to risk of specific breast cancer subtypes and to type of NSAID used...

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..The findings suggest that exposure to household pesticides is associated with an elevated risk of childhood leukemia and further indicate the importance of the timing and location of exposure...

..We take the opportunity to address the relationship between recent adult diet and breast cancer risk during the first two years of follow-up of the large California Teachers Study cohort...

..In particular, nondifferential misclassification of exposure might have masked true, weak associations...

..Whether alcohol consumption influences ovarian cancer risk is unclear. Therefore, we investigated the association between alcohol intake at various ages and risk of ovarian cancer...

..To evaluate the reliability and validity of a food-frequency questionnaire (FFQ) and database designed to quantify phytoestrogen consumption...

..We hope to provide the reader with an understanding of the challenge and promise that characterizes the current and future directions in childhood leukemia research...

..Although dietary consumption of isoflavones may be associated with decreased ovarian cancer risk, most dietary factors are unlikely to play a major role in ovarian cancer development...