Joel L Pomerantz

Summary

Affiliation: California Institute of Technology
Country: USA

Publications

  1. ncbi CARD11 mediates factor-specific activation of NF-kappaB by the T cell receptor complex
    Joel L Pomerantz
    Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    EMBO J 21:5184-94. 2002
  2. ncbi Inhibition of DNA binding by NF-kappa B with pyrrole-imidazole polyamides
    Nicholas R Wurtz
    Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA
    Biochemistry 41:7604-9. 2002
  3. ncbi Two pathways to NF-kappaB
    Joel L Pomerantz
    Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Mol Cell 10:693-5. 2002
  4. ncbi Phosphorylation of the CARMA1 linker controls NF-kappaB activation
    Karen Sommer
    Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Immunity 23:561-74. 2005
  5. ncbi The protein kinase C-responsive inhibitory domain of CARD11 functions in NF-kappaB activation to regulate the association of multiple signaling cofactors that differentially depend on Bcl10 and MALT1 for association
    Ryan R McCully
    Department of Biological Chemistry and Institute for Cell Engineering, The Johns Hopkins University School of Medicine, Broadway Research Building, Room 607, Baltimore, MD 21205, USA
    Mol Cell Biol 28:5668-86. 2008

Collaborators

  • P B Dervan
  • David Baltimore
  • Ryan R McCully
  • Karen Sommer
  • Nicholas R Wurtz
  • Miguel E Moreno-Garcia
  • Yulia L Ovechkina
  • Beichu Guo
  • David J Rawlings
  • Ashok D Bandaranayake

Detail Information

Publications5

  1. ncbi CARD11 mediates factor-specific activation of NF-kappaB by the T cell receptor complex
    Joel L Pomerantz
    Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    EMBO J 21:5184-94. 2002
    ..These results implicate CARD11 in factor- specific activation of NF-kappaB by the TCR complex and establish a role for a MAGUK family member in antigen receptor signaling...
  2. ncbi Inhibition of DNA binding by NF-kappa B with pyrrole-imidazole polyamides
    Nicholas R Wurtz
    Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA
    Biochemistry 41:7604-9. 2002
    ..Addition of NF-kappa B to the list of protein-DNA complexes that can be disrupted by minor groove binding ligands potentially increases the utility of polyamides as regulators of gene expression...
  3. ncbi Two pathways to NF-kappaB
    Joel L Pomerantz
    Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Mol Cell 10:693-5. 2002
    ..Four recent papers provide physiological roles for this pathway and expand our understanding of lymphoid development and organogenesis with potential applications in the treatment of autoimmune disease...
  4. ncbi Phosphorylation of the CARMA1 linker controls NF-kappaB activation
    Karen Sommer
    Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Immunity 23:561-74. 2005
    ..This PKC-dependent switch regulates accessibility of the CARD and CC domains and controls assembly and full activation of the membrane-associated IkappaB kinase (IKK) signalosome...
  5. ncbi The protein kinase C-responsive inhibitory domain of CARD11 functions in NF-kappaB activation to regulate the association of multiple signaling cofactors that differentially depend on Bcl10 and MALT1 for association
    Ryan R McCully
    Department of Biological Chemistry and Institute for Cell Engineering, The Johns Hopkins University School of Medicine, Broadway Research Building, Room 607, Baltimore, MD 21205, USA
    Mol Cell Biol 28:5668-86. 2008
    ..Using Bcl10- and MALT1-deficient cells, we show that CARD11 can recruit signaling cofactors independently of one another in a signal-inducible manner...