Elliot M Meyerowitz

Summary

Affiliation: California Institute of Technology
Country: USA

Publications

  1. ncbi Stem-cell homeostasis and growth dynamics can be uncoupled in the Arabidopsis shoot apex
    G Venugopala Reddy
    California Institute of Technology, Division of Biology, MC 156 29, 1200 East California Boulevard, Pasadena, CA 91125, USA
    Science 310:663-7. 2005
  2. ncbi Plants compared to animals: the broadest comparative study of development
    Elliot M Meyerowitz
    Division of Biology 156 29, California Institute of Technology, Pasadena, CA 91125, USA
    Science 295:1482-5. 2002
  3. ncbi Floral stem cell termination involves the direct regulation of AGAMOUS by PERIANTHIA
    Pradeep Das
    California Institute of Technology, Pasadena, California 91125, USA
    Development 136:1605-11. 2009
  4. ncbi Pattern formation during de novo assembly of the Arabidopsis shoot meristem
    Sean P Gordon
    Division of Biology, California Institute of Technology, Pasadena, CA, USA
    Development 134:3539-48. 2007
  5. ncbi Multiple feedback loops through cytokinin signaling control stem cell number within the Arabidopsis shoot meristem
    Sean P Gordon
    Division of Biology 156 29, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125, USA
    Proc Natl Acad Sci U S A 106:16529-34. 2009
  6. ncbi The homeotic protein AGAMOUS controls microsporogenesis by regulation of SPOROCYTELESS
    Toshiro Ito
    Division of Biology 156 29, California Institute of Technology, 1200 E California Blvd, Pasadena, California 91125, USA
    Nature 430:356-60. 2004
  7. ncbi Cell cycle regulates cell type in the Arabidopsis sepal
    Adrienne H K Roeder
    Division of Biology, California Institute of Technology, Pasadena, CA 91125 USA
    Development 139:4416-27. 2012
  8. ncbi Computational morphodynamics of plants: integrating development over space and time
    Adrienne H K Roeder
    Division of Biology 156 29, California Institute of Technology, 1200 E California Blvd, Pasadena, California 91125, USA
    Nat Rev Mol Cell Biol 12:265-73. 2011
  9. ncbi Cytokinin signaling as a positional cue for patterning the apical-basal axis of the growing Arabidopsis shoot meristem
    Vijay S Chickarmane
    Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Proc Natl Acad Sci U S A 109:4002-7. 2012
  10. ncbi Genome-wide analysis of gene expression during early Arabidopsis flower development
    Frank Wellmer
    Division of Biology, California Institute of Technology, Pasadena, California, USA
    PLoS Genet 2:e117. 2006

Collaborators

Detail Information

Publications48

  1. ncbi Stem-cell homeostasis and growth dynamics can be uncoupled in the Arabidopsis shoot apex
    G Venugopala Reddy
    California Institute of Technology, Division of Biology, MC 156 29, 1200 East California Boulevard, Pasadena, CA 91125, USA
    Science 310:663-7. 2005
    ....
  2. ncbi Plants compared to animals: the broadest comparative study of development
    Elliot M Meyerowitz
    Division of Biology 156 29, California Institute of Technology, Pasadena, CA 91125, USA
    Science 295:1482-5. 2002
    ..Evidence from studies of developmental mechanisms in both kingdoms, and data from genome-sequencing projects, indicate that development evolved independently in the lineages leading to plants and to animals...
  3. ncbi Floral stem cell termination involves the direct regulation of AGAMOUS by PERIANTHIA
    Pradeep Das
    California Institute of Technology, Pasadena, California 91125, USA
    Development 136:1605-11. 2009
    ..These results suggest that the termination of floral stem cell fate is a multiply redundant process involving loci with unrelated floral patterning functions...
  4. ncbi Pattern formation during de novo assembly of the Arabidopsis shoot meristem
    Sean P Gordon
    Division of Biology, California Institute of Technology, Pasadena, CA, USA
    Development 134:3539-48. 2007
    ..We propose that de novo shoot meristem induction is an easily accessible system for the study of patterning and self-organization in the well-studied model organism Arabidopsis...
  5. ncbi Multiple feedback loops through cytokinin signaling control stem cell number within the Arabidopsis shoot meristem
    Sean P Gordon
    Division of Biology 156 29, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125, USA
    Proc Natl Acad Sci U S A 106:16529-34. 2009
    ..Our results also may explain how increasing cytokinin concentration leads to the first steps in reestablishing the shoot stem cell niche in vitro...
  6. ncbi The homeotic protein AGAMOUS controls microsporogenesis by regulation of SPOROCYTELESS
    Toshiro Ito
    Division of Biology 156 29, California Institute of Technology, 1200 E California Blvd, Pasadena, California 91125, USA
    Nature 430:356-60. 2004
    ..Furthermore, we demonstrate that SPL can induce microsporogenesis in the absence of AG function, suggesting that AG controls a specific process during organogenesis by activating another regulator that performs a subset of its functions...
  7. ncbi Cell cycle regulates cell type in the Arabidopsis sepal
    Adrienne H K Roeder
    Division of Biology, California Institute of Technology, Pasadena, CA 91125 USA
    Development 139:4416-27. 2012
    ..Conversely, endoreduplication represses small cell identity. These results show not only that cell type affects cell cycle regulation, but also that changes in the cell cycle can regulate cell type...
  8. ncbi Computational morphodynamics of plants: integrating development over space and time
    Adrienne H K Roeder
    Division of Biology 156 29, California Institute of Technology, 1200 E California Blvd, Pasadena, California 91125, USA
    Nat Rev Mol Cell Biol 12:265-73. 2011
    ..The strength of the field comes from the iterative and combined use of these techniques, which has provided important insights into plant development...
  9. ncbi Cytokinin signaling as a positional cue for patterning the apical-basal axis of the growing Arabidopsis shoot meristem
    Vijay S Chickarmane
    Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Proc Natl Acad Sci U S A 109:4002-7. 2012
    ..These results suggest a plausible dynamic feedback principle by which the SAM stem cell niche is patterned...
  10. ncbi Genome-wide analysis of gene expression during early Arabidopsis flower development
    Frank Wellmer
    Division of Biology, California Institute of Technology, Pasadena, California, USA
    PLoS Genet 2:e117. 2006
    ....
  11. ncbi Alignment between PIN1 polarity and microtubule orientation in the shoot apical meristem reveals a tight coupling between morphogenesis and auxin transport
    Marcus G Heisler
    Division of Biology, California Institute of Technology, Pasadena, California, United States of America
    PLoS Biol 8:e1000516. 2010
    ..Lastly, through mathematical modeling we show that such a biophysical coupling could mediate the feedback loop between auxin and its transport that underlies plant phyllotaxis...
  12. ncbi Redundancy and specialization among plant microRNAs: role of the MIR164 family in developmental robustness
    Patrick Sieber
    Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Development 134:1051-60. 2007
    ....
  13. ncbi Arabidopsis regeneration from multiple tissues occurs via a root development pathway
    Kaoru Sugimoto
    Division of Biology 156 29, California Institute of Technology, Pasadena, CA 91125, USA
    Dev Cell 18:463-71. 2010
    ..It thus appears that the ectopic activation of a lateral root development program is a common mechanism in callus formation from multiple organs...
  14. ncbi Patterns of auxin transport and gene expression during primordium development revealed by live imaging of the Arabidopsis inflorescence meristem
    Marcus G Heisler
    Division of Biology, California Institute of Technology, Pasadena 91125, USA
    Curr Biol 15:1899-911. 2005
    ..CONCLUSIONS: These results provide new insight into auxin transport dynamics during primordial positioning and suggest a role for auxin transport in influencing primordial cell type...
  15. ncbi The early extra petals1 mutant uncovers a role for microRNA miR164c in regulating petal number in Arabidopsis
    Catherine C Baker
    Division of Biology, California Institute of Technology, Pasadena, CA 91125 USA
    Curr Biol 15:303-15. 2005
    ..A loss-of-function allele of MIR164b did not result in a mutant phenotype, possibly because of functional redundancy among the three members of the MIR164 family...
  16. ncbi Computational analysis of live cell images of the Arabidopsis thaliana plant
    Alexandre Cunha
    Center for Advanced Computing Research, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, California, USA
    Methods Cell Biol 110:285-323. 2012
    ..We illustrate the application of these procedures in investigations aiming to unravel the mechanical and biochemical signaling mechanisms responsible for the coordinated growth and patterning in plants...
  17. ncbi Global expression profiling applied to the analysis of Arabidopsis stamen development
    Marcio Alves Ferreira
    California Institute of Technology, Division of Biology, Pasadena, California 91125, USA
    Plant Physiol 145:747-62. 2007
    ....
  18. ncbi An evolutionarily conserved pseudokinase mediates stem cell production in plants
    ZACHARY L NIMCHUK
    Division of Biology 156 29, California Institute of Technology, Pasadena, California 91125, USA
    Plant Cell 23:851-4. 2011
    ....
  19. ncbi Plant stem cell signaling involves ligand-dependent trafficking of the CLAVATA1 receptor kinase
    ZACHARY L NIMCHUK
    Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Curr Biol 21:345-52. 2011
    ..There are many questions regarding the CLV3/CLV1 interaction, including where in the meristem it occurs, how it is regulated, and how it is that a large range of CLV3 concentrations gives no meristem size phenotype...
  20. ncbi Transcriptome-wide analysis of uncapped mRNAs in Arabidopsis reveals regulation of mRNA degradation
    Yuling Jiao
    California Institute of Technology, Division of Biology 156 29, Pasadena, California 91125, USA
    Plant Cell 20:2571-85. 2008
    ..These transcriptome-wide profiles of uncapped mRNAs will aid in illuminating new regulatory mechanisms of eukaryotic transcriptional networks...
  21. ncbi MscS-like proteins control plastid size and shape in Arabidopsis thaliana
    Elizabeth S Haswell
    Division of Biology, 156 29, California Institute of Technology, 1200 E California Blvd, Pasadena, California 91125, USA
    Curr Biol 16:1-11. 2006
    ..MscS-like proteins are found widely in bacterial and archaeal species and have also been identified in fission yeast and plants. None of the eukaryotic members of the family have yet been characterized...
  22. ncbi HANABA TARANU is a GATA transcription factor that regulates shoot apical meristem and flower development in Arabidopsis
    Yuanxiang Zhao
    Division of Biology, California Institute of Technology, Pasadena, California 91125, USA
    Plant Cell 16:2586-600. 2004
    ..Ectopic HAN expression causes growth retardation, aberrant cell division patterns, and loss of meristem activity, suggesting that HAN is involved in controlling cell proliferation and differentiation...
  23. ncbi Variability in the control of cell division underlies sepal epidermal patterning in Arabidopsis thaliana
    Adrienne H K Roeder
    Division of Biology, California Institute of Technology, Pasadena, California, United States of America
    PLoS Biol 8:e1000367. 2010
    ..Models and observations together demonstrate that variability in the time of cell division is a major determinant in the formation of a characteristic pattern...
  24. ncbi Real-time lineage analysis reveals oriented cell divisions associated with morphogenesis at the shoot apex of Arabidopsis thaliana
    G Venugopala Reddy
    California Institute of Technology, Division of Biology, MC 156-29, 1200 E. California Boulevard, Pasadena, CA 91125, USA
    Development 131:4225-37. 2004
    ..Distinct lack of cell expansion is seen in a narrow band of cells, which forms the boundary region between developing flower bud and the SAM. We discuss these results in the context of SAM morphogenesis...
  25. ncbi Floral induction in tissue culture: a system for the analysis of LEAFY-dependent gene regulation
    Doris Wagner
    Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Plant J 39:273-82. 2004
    ..Thus, the floral induction system is suitable for the detection of low abundance transcripts whose expression is controlled in an LFY-dependent manner...
  26. ncbi Whorl-specific expression of the SUPERMAN gene of Arabidopsis is mediated by cis elements in the transcribed region
    Toshiro Ito
    Division of Biology 156-29, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125, USA
    Curr Biol 13:1524-30. 2003
    ....
  27. ncbi Computational morphodynamics: a modeling framework to understand plant growth
    Vijay Chickarmane
    Division of Biology, California Institute Technology, Pasadena, California 91125, USA
    Annu Rev Plant Biol 61:65-87. 2010
    ....
  28. ncbi Segmenting the sepal and shoot apical meristem of Arabidopsis thaliana
    Alexandre L Cunha
    Center for Advanced Computing Research, Pasadena, California 91125, USA
    Conf Proc IEEE Eng Med Biol Soc 2010:5338-42. 2010
    ....
  29. ncbi Regeneration in plants and animals: dedifferentiation, transdifferentiation, or just differentiation?
    Kaoru Sugimoto
    Division of Biology 156 29, California Institute of Technology, Pasadena, CA 91125, USA
    Trends Cell Biol 21:212-8. 2011
    ..We review here some of these data, compare plant and animal regeneration, and argue that the importance of dedifferentiation and plasticity in regenerating systems is due for reevaluation...
  30. ncbi Cell-type specific analysis of translating RNAs in developing flowers reveals new levels of control
    Yuling Jiao
    Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Mol Syst Biol 6:419. 2010
    ..Finally, we identified a new class of noncoding RNAs associated with polysomes. Findings from our profiling lead to new hypotheses in the understanding of flower development...
  31. ncbi Two MscS homologs provide mechanosensitive channel activities in the Arabidopsis root
    Elizabeth S Haswell
    Division of Biology 156 29, California Institute of Technology, Pasadena, CA 91125, USA
    Curr Biol 18:730-4. 2008
    ..This is the first molecular identification and characterization of MS channels in plant membranes...
  32. ncbi Genome-wide analysis of spatial gene expression in Arabidopsis flowers
    Frank Wellmer
    California Institute of Technology, Division of Biology 156-29, Pasadena, California 91125, USA
    Plant Cell 16:1314-26. 2004
    ..These findings indicate that spatially limited expression of a large number of genes is part of flower development and that its extent differs significantly between the reproductive organs and the organs of the perianth...
  33. ncbi Floral homeotic genes are targets of gibberellin signaling in flower development
    Hao Yu
    Division of Biology 156-29, California Institute of Technology, Pasadena, CA 91125, USA
    Proc Natl Acad Sci U S A 101:7827-32. 2004
    ..Our results indicate that GA promotes the expression of floral homeotic genes by antagonizing the effects of DELLA proteins, thereby allowing continued flower development...
  34. ncbi Repression of AGAMOUS-LIKE 24 is a crucial step in promoting flower development
    Hao Yu
    Division of Biology 156 29, California Institute of Technology, Pasadena, California 91125, USA
    Nat Genet 36:157-61. 2004
    ..This indicates that LFY and AP1 promote floral development not only by positively regulating genes activated in flower development, but also by repressing AGL24, a promoter of inflorescence fate...
  35. ncbi SPLAYED, a novel SWI/SNF ATPase homolog, controls reproductive development in Arabidopsis
    Doris Wagner
    Division of Biology 156 29, California Institute of Technology, Pasadena, CA 91125, USA
    Curr Biol 12:85-94. 2002
    ..Available data suggests that, while LFY activity is controlled via interaction with tissue-specific coactivators, other mechanisms exist that regulate LFY activity, the identity of which are not known...
  36. ncbi A computational image analysis glossary for biologists
    Adrienne H K Roeder
    Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Development 139:3071-80. 2012
    ..In this Primer we present a glossary of image analysis terms to aid biologists and briefly discuss the importance of robust image analysis in developmental studies...
  37. ncbi Regeneration in Arabidopsis tissue culture
    Kaoru Sugimoto
    Division of Biology 156 29, California Institute of Technology, Pasadena, CA, USA
    Methods Mol Biol 959:265-75. 2013
    ..Here we describe a standard protocol for regenerating Arabidopsis plants in tissue culture, and for preparing and observing samples using confocal microscopy to study cells during regeneration...
  38. ncbi The Arabidopsis JAGGED gene encodes a zinc finger protein that promotes leaf tissue development
    Carolyn K Ohno
    Division of Biology 156 29, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125, USA
    Development 131:1111-22. 2004
    ..Thus, JAG is necessary for proper lateral organ shape and is sufficient to induce the proliferation of lateral organ tissue...
  39. ncbi An auxin-driven polarized transport model for phyllotaxis
    Henrik Jonsson
    Computational Biology and Biological Physics Group, Department of Theoretical Physics, Lund University, S 221 00 Lund, Sweden
    Proc Natl Acad Sci U S A 103:1633-8. 2006
    ..The model shows how polarized transport can drive the formation of regular patterns...
  40. ncbi ABERRANT TESTA SHAPE encodes a KANADI family member, linking polarity determination to separation and growth of Arabidopsis ovule integuments
    Jessica Messmer McAbee
    Section of Molecular Biology, University of California, 1 Shields Ave, Davis, CA 95616, USA
    Plant J 46:522-31. 2006
    ..Together, these two hypotheses lead us to propose a model for normal integument growth that also explains the described mutant phenotypes...
  41. ncbi Transformation of shoots into roots in Arabidopsis embryos mutant at the TOPLESS locus
    Jeff A Long
    Department of Genetics and Program in Cellular and Molecular Biology, University of Wisconsin-Madison, Madison, WI, USA
    Development 129:2797-806. 2002
    ....
  42. ncbi The homeotic protein AGAMOUS controls late stamen development by regulating a jasmonate biosynthetic gene in Arabidopsis
    Toshiro Ito
    Temasek Life Sciences Laboratory, National University of Singapore, Singapore 117604, Singapore
    Plant Cell 19:3516-29. 2007
    ....
  43. ncbi Modeling the organization of the WUSCHEL expression domain in the shoot apical meristem
    Henrik Jonsson
    Department of Theoretical Physics, Complex Systems Division, Lund University Sweden
    Bioinformatics 21:i232-40. 2005
    ..Predictive mathematical models describing the system should provide a useful tool for investigating and discriminating among possible hypotheses, by determining which hypotheses best explain observed gene expression dynamics...
  44. ncbi Microarray analysis reveals altered expression of a large number of nuclear genes in developing cytoplasmic male sterile Brassica napus flowers
    Jenny Carlsson
    Department of Plant Biology and Forest Genetics, Swedish University of Agricultural Sciences, Box 7080, SE 750 07 Uppsala, Sweden
    Plant J 49:452-62. 2007
    ..These results suggest that AP3 expression in stamens depends on proper mt function and a correct nuclear-mt interaction, and that mt alterations cause the male sterility phenotype of the CMS line...
  45. ncbi Antagonistic regulation of PIN phosphorylation by PP2A and PINOID directs auxin flux
    Marta Michniewicz
    Zentrum für Molekularbiologie der Pflanzen, Universitat Tubingen, Tubingen, Germany
    Cell 130:1044-56. 2007
    ..In the case of PIN proteins, this mechanism enables switches in the direction of intercellular auxin fluxes, which mediate differential growth, tissue patterning, and organogenesis...
  46. ncbi TOPLESS regulates apical embryonic fate in Arabidopsis
    Jeff A Long
    Plant Biology Laboratory, Salk Institute for Biological Sciences, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
    Science 312:1520-3. 2006
    ..These data point to a transcriptional repression mechanism that prevents root formation in the shoot pole during Arabidopsis embryogenesis...
  47. ncbi The impact of Arabidopsis on human health: diversifying our portfolio
    Alan M Jones
    Department of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Cell 133:939-43. 2008
    ..Many discoveries with direct relevance to human health and disease have been elaborated using Arabidopsis, and several processes important to human biology are more easily studied in this versatile model plant...
  48. ncbi Unravelling developmental dynamics: transient intervention and live imaging in plants
    G Venugopala Reddy
    Department of Botany and Plant Sciences, 2150 Batchelor Hall, University of California, Riverside, California 92521, USA
    Nat Rev Mol Cell Biol 8:491-501. 2007
    ..In this Review, we emphasize the insights gained from simultaneous use of live imaging and transient perturbation technologies to capture the dynamic properties of plant processes...