Affiliation: California Pacific Medical Center Research Institute
- Targeting Id1 reduces proliferation and invasion in aggressive human salivary gland cancer cellsTomoki Sumida
Department of Oral and Maxillofacial Surgery, Ehime University School of Medicine, 454 Shitsukawa, Toon City, Ehime, 791 0295, Japan
BMC Cancer 13:141. 2013..In this study, our goal was to determine the potential role of Id proteins, particularly Id1, during human SGC cell progression...
- Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cellsSean D McAllister
California Pacific Medical Center, Research Institute, 475 Brannan Street, San Francisco, CA 94107, USA
Mol Cancer Ther 6:2921-7. 2007..In conclusion, CBD represents the first nontoxic exogenous agent that can significantly decrease Id-1 expression in metastatic breast cancer cells leading to the down-regulation of tumor aggressiveness...
- Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasisSean D McAllister
California Pacific Medical Center, Research Institute, San Francisco, CA 94107, USA
Breast Cancer Res Treat 129:37-47. 2011....
- Cannabidiol enhances the inhibitory effects of delta9-tetrahydrocannabinol on human glioblastoma cell proliferation and survivalJahan P Marcu
California Pacific Medical Center Research Institute, San Francisco, California 94107, USA
Mol Cancer Ther 9:180-9. 2010..Our results suggest that the addition of cannabidiol to Delta(9)-THC may improve the overall effectiveness of Delta(9)-THC in the treatment of glioblastoma in cancer patients...
- Cannabinoids selectively inhibit proliferation and induce death of cultured human glioblastoma multiforme cellsSean D McAllister
California Pacific Medical Center Research Institute, 475 Brannan St, Suite 220, San Francisco, CA 94107, USA
J Neurooncol 74:31-40. 2005..Evidence of selective efficacy with WIN 55,212-2 was also observed but the selectivity was less profound, and the synthetic agonist produced a greater disruption of normal cell morphology compared to Delta(9)-THC...
- Cannabinoids Control Breast Cancer Progression Through Id-1Sean D McAllister; Fiscal Year: 2010..This research could lead to new areas of investigation in the treatment of aggressive forms of breast cancer, which spread to other parts of the body, with novel cannabinoid compounds such as analogs of cannabidiol. ..