Hao Yuan Kueh

Summary

Affiliation: California Institute of Technology
Country: USA

Publications

  1. doi request reprint Positive feedback between PU.1 and the cell cycle controls myeloid differentiation
    Hao Yuan Kueh
    Division of Biology, California Institute of Technology, Pasadena, CA, USA
    Science 341:670-3. 2013
  2. pmc Maintenance of mitochondrial oxygen homeostasis by cosubstrate compensation
    Hao Yuan Kueh
    Department of Systems Biology, Harvard Medical School, Boston, MA, USA
    Biophys J 104:1338-48. 2013
  3. pmc Quantitative analysis of actin turnover in Listeria comet tails: evidence for catastrophic filament turnover
    Hao Yuan Kueh
    Department of Systems Biology, Harvard University, Cambridge, MA, USA
    Biophys J 99:2153-62. 2010
  4. pmc Actin disassembly by cofilin, coronin, and Aip1 occurs in bursts and is inhibited by barbed-end cappers
    Hao Yuan Kueh
    Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA
    J Cell Biol 182:341-53. 2008
  5. pmc Dynamic stabilization of actin filaments
    Hao Yuan Kueh
    Department of Systems Biology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 105:16531-6. 2008
  6. pmc Spatial patterning of metabolism by mitochondria, oxygen, and energy sinks in a model cytoplasm
    Philipp Niethammer
    Department of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Curr Biol 18:586-91. 2008
  7. pmc Structural plasticity in actin and tubulin polymer dynamics
    Hao Yuan Kueh
    Department of Systems Biology, Harvard Medical School, Boston, MA 02215, USA
    Science 325:960-3. 2009
  8. pmc A far downstream enhancer for murine Bcl11b controls its T-cell specific expression
    Long Li
    Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Blood 122:902-11. 2013
  9. pmc Regulatory gene network circuits underlying T cell development from multipotent progenitors
    Hao Yuan Kueh
    Division of Biology, California Institute of Technology, Pasadena, CA, USA
    Wiley Interdiscip Rev Syst Biol Med 4:79-102. 2012
  10. pmc Rapid actin monomer-insensitive depolymerization of Listeria actin comet tails by cofilin, coronin, and Aip1
    William M Brieher
    Department of Systems Biology and 2Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA
    J Cell Biol 175:315-24. 2006

Detail Information

Publications10

  1. doi request reprint Positive feedback between PU.1 and the cell cycle controls myeloid differentiation
    Hao Yuan Kueh
    Division of Biology, California Institute of Technology, Pasadena, CA, USA
    Science 341:670-3. 2013
    ..These results show that cell cycle duration functions as an integral part of a positive autoregulatory circuit to control cell fate. ..
  2. pmc Maintenance of mitochondrial oxygen homeostasis by cosubstrate compensation
    Hao Yuan Kueh
    Department of Systems Biology, Harvard Medical School, Boston, MA, USA
    Biophys J 104:1338-48. 2013
    ..Our findings indicate that CSC constitutes a robust control strategy for homeostasis and adaptation in cellular biochemical networks...
  3. pmc Quantitative analysis of actin turnover in Listeria comet tails: evidence for catastrophic filament turnover
    Hao Yuan Kueh
    Department of Systems Biology, Harvard University, Cambridge, MA, USA
    Biophys J 99:2153-62. 2010
    ..By keeping filament lengths largely constant over time, such catastrophic filament turnover may enable cellular actin assemblies to maintain their mechanical integrity as they are turning over...
  4. pmc Actin disassembly by cofilin, coronin, and Aip1 occurs in bursts and is inhibited by barbed-end cappers
    Hao Yuan Kueh
    Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA
    J Cell Biol 182:341-53. 2008
    ..The differential effects of drugs in cells argue for physiological relevance of this new disassembly pathway and potentially explain discordant results previously found with these drugs...
  5. pmc Dynamic stabilization of actin filaments
    Hao Yuan Kueh
    Department of Systems Biology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 105:16531-6. 2008
    ..Our results suggest that plasticity in the internal structure of the actin filament may play a fundamental role in regulating actin dynamics and may help cells build actin assemblies with vastly different turnover rates...
  6. pmc Spatial patterning of metabolism by mitochondria, oxygen, and energy sinks in a model cytoplasm
    Philipp Niethammer
    Department of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Curr Biol 18:586-91. 2008
    ....
  7. pmc Structural plasticity in actin and tubulin polymer dynamics
    Hao Yuan Kueh
    Department of Systems Biology, Harvard Medical School, Boston, MA 02215, USA
    Science 325:960-3. 2009
    ..We refer to these phenomena as "structural plasticity" and discuss emerging evidence that they play a central role in polymer dynamics and function...
  8. pmc A far downstream enhancer for murine Bcl11b controls its T-cell specific expression
    Long Li
    Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Blood 122:902-11. 2013
    ..Thus, promoter-proximal and Major Peak sequences are cis-regulatory elements that interact over 850 kb to control expression of Bcl11b in hematopoietic cells. ..
  9. pmc Regulatory gene network circuits underlying T cell development from multipotent progenitors
    Hao Yuan Kueh
    Division of Biology, California Institute of Technology, Pasadena, CA, USA
    Wiley Interdiscip Rev Syst Biol Med 4:79-102. 2012
    ..Here, we examine the roles of these circuits in facilitating different aspects of the decision making process, and discuss experiments to further probe their structure and function...
  10. pmc Rapid actin monomer-insensitive depolymerization of Listeria actin comet tails by cofilin, coronin, and Aip1
    William M Brieher
    Department of Systems Biology and 2Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA
    J Cell Biol 175:315-24. 2006
    ..The cooperative activities of cofilin, coronin, and Aip1 should provide a biochemical basis for understanding how actin filaments can grow in some places in the cell while shrinking in others...