Research Topics
| Grady HanrahanSummaryAffiliation: California Lutheran University Country: USA Publications
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Detail Information
Publications
Chemometric experimental design based optimization techniques in capillary electrophoresis: a critical review of modern applicationsGrady Hanrahan
Department of Chemistry and Biochemistry, California State University, Los Angeles, Los Angeles, CA 90032, USA
Anal Bioanal Chem 390:169-79. 2008..Furthermore, future perspectives in the use of chemometric methodology in capillary electrophoresis are considered...
Swarm intelligence metaheuristics for enhanced data analysis and optimizationGrady Hanrahan
Department of Chemistry, California Lutheran University, 60 West Olsen Road, Thousand Oaks, CA 91360, USA
Analyst 136:3587-94. 2011..Consideration will be given to algorithm development, ease of implementation and model performance, detailing subsequent influences on a number of application areas in the analytical, bioanalytical and detection sciences...
Computational neural networks driving complex analytical problem solvingGrady Hanrahan
Applied Analytical Chemistry, California Lutheran University, CA 91360, USA
Anal Chem 82:4307-13. 2010..To listen to a podcast about this article, please go to the Analytical Chemistry multimedia page at pubs.acs.org/page/ancham/audio/index.html .)...
Use of chemometric methodology in optimizing conditions for competitive binding partial filling affinity capillary electrophoresisRuth E Montes
Department of Chemistry and Biochemistry, California State University, Los Angeles, CA, USA
Electrophoresis 29:3325-32. 2008..3 min, voltage = 11.6 kV, [L(o)] = 1.4 microM). The achieved results greatly extend the usefulness of chemometrics in ACE and provide a valuable statistical tool for the study of other receptor-ligand combinations...
Chemometrical examination of active parameters and interactions in flow injection-capillary electrophoresisFroseen T Dahdouh
Department of Chemistry and Biochemistry, California State University, Los Angeles, CA 90032, USA
Electrophoresis 29:3779-85. 2008..This work is not only highly significant for advancing FI-CE developments, but instructive for investigators actively exploring other coupled analytical techniques and associated experimental parameters...
Application of artificial neural networks in the prediction of product distribution in electrophoretically mediated microanalysisToni Ann Riveros
Department of Chemistry and Biochemistry, California State University, State University Drive, Los Angeles, CA 90032, USA
Electrophoresis 30:2385-9. 2009..Model validation addressing the extent of reaction and product ratios were subsequently determined experimentally in replicate analyses, with results shown to be in good agreement (<10% discrepancy difference) with predicted data...
Implementation of a genetically tuned neural platform in optimizing fluorescence from receptor-ligand binding interactions on microchipsJudith Alvarado
Department of Chemistry and Biochemistry, California State University, Los Angeles, CA, USA
Electrophoresis 33:2711-7. 2012..967) data. Simulated results were experimentally validated demonstrating efficiency of the neural network approach and proved superior to the use of multiple linear regression and neural networks using standard back propagation...
Biologically driven neural platform invoking parallel electrophoretic separation and urinary metabolite screeningTessa Page
Department of Chemistry, California Lutheran University, Thousand Oaks, CA 91360, USA
Anal Bioanal Chem 403:2367-75. 2012..Adaptable pseudo-code is provided to enable users of varied software packages and modeling framework to implement the PSO algorithm for their desired use...
On-capillary derivatization using a hybrid artificial neural network-genetic algorithm approachToni Riveros
Department of Chemistry and Biochemistry, California State University, Los Angeles, 5151 State University Drive, Los Angeles, CA 90032, USA
Analyst 134:2067-70. 2009..The model developed will likely prove useful for the analysis of other organic-based reaction systems...
Evolving neural network optimization of cholesteryl ester separation by reversed-phase HPLCMichael A Jansen
Department of Biological Sciences, California State University Los Angeles, Los Angeles, CA 90032, USA
Anal Bioanal Chem 397:2367-74. 2010....
Reduced inorganic phosphorus in the natural environment: significance, speciation and determinationGrady Hanrahan
Department of Chemistry and Biochemistry, California State University, Los Angeles, CA 90032, USA
Talanta 66:435-44. 2005..This paper discusses the significance of reduced phosphorus in the natural environment, its speciation and methods of detection...
Response surface examination of the relationship between experimental conditions and product distribution in electrophoretically mediated microanalysisRuth E Montes
Department of Chemistry, California Lutheran University, Thousand Oaks, CA, USA
Electrophoresis 29:375-80. 2008....
Detection of geothermal phosphite using high-performance liquid chromatographyHerbe Pech
Department of Chemistry and Biochemistry, California State University, Los Angeles, California 90032, USA
Environ Sci Technol 43:7671-5. 2009..04 microM) and phosphate was measured at 1.06 +/- 0.36 microM. The presence of phosphite in the geothermal pool was confirmed using both chemical oxidation and ion chromatography/mass spectrometry...
Design and development of a flow injection-capillary electrophoresis analyzer employing fiber optic detectionGrady Hanrahan
Department of Chemistry and Biochemistry, California State University, Los Angeles, CA 90032, USA
J Capill Electrophor Microchip Technol 10:1-6. 2007..Future directions in terms of instrument automation and incorporation into a microfluidic format are also discussed...
Design and development of an automated flow injection instrument for the determination of arsenic species in natural watersGrady Hanrahan
Department of Chemistry, California Lutheran University, 60 West Olsen Road, Thousand Oaks, California 91360 2787, USA
Rev Sci Instrum 80:104101. 2009..Spiked ultrapure water samples were analyzed and recoveries were found to be 97%-101% for As(III) and 95%-99% for As(V), respectively. Future directions in terms of automation, optimization, and field deployment are discussed...
Implementation of chemometric methodology in ACE: predictive investigation of protein-ligand bindingGrady Hanrahan
Department of Chemistry and Biochemistry, California State University, Los Angeles, CA 90032, USA
Electrophoresis 28:2853-60. 2007..The adequacy of the model was validated by experimental runs with the predicted model solution (capillary length = 47 cm, voltage = 11 kV, injection time = 0.01 min) presented in detail as an example...
