Research Topics
Genomes and GenesSpecies | Jan GläscherSummaryAffiliation: California Institute of Technology Country: USA Publications
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Detail Information
Publications
Formal learning theory dissociates brain regions with different temporal integrationJan Gläscher
NeuroImage Nord, Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, Martinistrasse 52, D 20246 Hamburg, Germany
Neuron 47:295-306. 2005....
Determining a role for ventromedial prefrontal cortex in encoding action-based value signals during reward-related decision makingJan Gläscher
Division of Humanities and Social Sciences, California Institute of Technology, MC 114 96, 1200 E California Boulevard, Pasadena, CA 91125, USA
Cereb Cortex 19:483-95. 2009..These findings suggest that ventromedial prefrontal cortex may play a role in encoding the value of chosen actions irrespective of whether those actions denote physical motor responses or more abstract decision options...
States versus rewards: dissociable neural prediction error signals underlying model-based and model-free reinforcement learningJan Gläscher
Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, CA 91101, USA
Neuron 66:585-95. 2010..This finding supports the existence of two unique forms of learning signal in humans, which may form the basis of distinct computational strategies for guiding behavior...
Distributed neural system for general intelligence revealed by lesion mappingJ Gläscher
Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, CA 91125, USA
Proc Natl Acad Sci U S A 107:4705-9. 2010..We suggest that general intelligence draws on connections between regions that integrate verbal, visuospatial, working memory, and executive processes...
Visualization of group inference data in functional neuroimagingJan Gläscher
California Institute of Technology, Pasadena, 91125, USA
Neuroinformatics 7:73-82. 2009..The large variety of plot options renders rfxplot suitable both for data exploration as well as producing high-quality figures for publications...
Independent effects of emotion and working memory load on visual activation in the lateral occipital complexJan Gläscher
Department of Systems Neuroscience, NeuroImage Nord, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany
J Neurosci 27:4366-73. 2007..A connectivity analysis suggests that the emotional modulation might originate in the amygdalo-hippocampal junction...
Lesion mapping of cognitive control and value-based decision making in the prefrontal cortexJan Gläscher
Division of Humanities and Social Sciences and Biology, California Institute of Technology, Pasadena, CA 91125, USA
Proc Natl Acad Sci U S A 109:14681-6. 2012..By contrast, regions in the ventral PFC were required for decision-making. These findings provide detailed causal evidence for a remarkable functional-anatomical specificity in the human PFC...
fMRI reveals how pain modulates visual object processing in the ventral visual streamUlrike Bingel
NeuroImage Nord, Department of Neurology, University Medical Center Hamburg Eppendorf, Germany
Neuron 55:157-67. 2007....
Subregions of the ventral striatum show preferential coding of reward magnitude and probabilityJuliana Yacubian
NeuroImage Nord, Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, Martinistr 52, D 20246, Hamburg, Germany
Neuroimage 38:557-63. 2007....
Emotional enhancement effect of memory: removing the influence of cognitive factorsTobias Sommer
NeuroImage Nord, Department of Systems Neuroscience, University of Hamburg Medical School, Hamburg 20246, Germany
Learn Mem 15:569-73. 2008..We observed the characteristic neuronal correlates of the EEM, in particular enhanced activity in the amygdala and hippocampus, which provides evidence for an arousal-driven EEM in the amygdala as proposed by the modulation hypothesis...
Structure-function relationships in the processing of regret in the orbitofrontal cortexTobias Sommer
Department of Systems Neuroscience, NeuroImage Nord, University of Hamburg Medical School, Bldg S10, Hamburg, Germany
Brain Struct Funct 213:535-51. 2009..Vice versa, the differential contribution of OFC subregions to these processes also adds evidence to the current debate on the function of this cortical structure in decision-making that attracted increasing attention in recent years...
Lesion mapping of cognitive abilities linked to intelligenceJan Gläscher
Division of Humanities and Social Sciences, Caltech, Pasadena, CA 91125, USA
Neuron 61:681-91. 2009..Our findings provide comprehensive lesion maps of intelligence factors, and make specific recommendations for interpretation and application of the WAIS to the study of intelligence in health and disease...
Personal space regulation by the human amygdalaDaniel P Kennedy
Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, California, USA
Nat Neurosci 12:1226-7. 2009..The amygdala may be required to trigger the strong emotional reactions normally following personal space violations, thus regulating interpersonal distance in humans...
Gene-gene interaction associated with neural reward sensitivityJuliana Yacubian
NeuroImage Nord, Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
Proc Natl Acad Sci U S A 104:8125-30. 2007..In view of a consistent relationship between reduced reward sensitivity and addiction, our findings point to a potential genetic basis for vulnerability to addiction...
Elevated responses to constant facial emotions in different faces in the human amygdala: an fMRI study of facial identity and expressionJan Gläscher
NeuroImage Nord, Department of Neurology, University Hospital Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
BMC Neurosci 5:45. 2004....
Neural dynamics of learning sound-action associationsAdam McNamara
NeuroImage Nord, Department of Neurology, UKSH, Luebeck, Germany
PLoS ONE 3:e3845. 2008....
Processing of the arousal of subliminal and supraliminal emotional stimuli by the human amygdalaJan Gläscher
NeuroImage Nord, Department of Neurology, University Hospital Hamburg Eppendorf, University of Hamburg, D 20246 Hamburg, Germany
J Neurosci 23:10274-82. 2003....
Neural correlates of memory confidenceSteffen Moritz
Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
Neuroimage 33:1188-93. 2006..In contrast, increments in doubt were solely related to activation in the superior posterior parietal cortex. To conclude, the study provides some evidence for dissociable systems for confidence and doubt...
Pathological gambling is linked to reduced activation of the mesolimbic reward systemJan Reuter
NeuroImage Nord, Department of Neurology, Hamburg University Hospital Eppendorf, Martinistr. 52, 20246 Hamburg, Germany
Nat Neurosci 8:147-8. 2005....
Dissociable systems for gain- and loss-related value predictions and errors of prediction in the human brainJuliana Yacubian
Department of Systems Neuroscience, NeuroImage Nord, University Medical Center Hamburg-Eppendorf, D-20246 Hamburg, Germany
J Neurosci 26:9530-7. 2006..Prevalence of either part might render expectations more positive or negative, which could contribute to the pathophysiology of mood disorders like major depression...
