Jan Gläscher

Summary

Affiliation: California Institute of Technology
Country: USA

Publications

  1. ncbi request reprint Formal learning theory dissociates brain regions with different temporal integration
    Jan Gläscher
    NeuroImage Nord, Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, Martinistrasse 52, D 20246 Hamburg, Germany
    Neuron 47:295-306. 2005
  2. pmc Determining a role for ventromedial prefrontal cortex in encoding action-based value signals during reward-related decision making
    Jan Gläscher
    Division of Humanities and Social Sciences, California Institute of Technology, MC 114 96, 1200 E California Boulevard, Pasadena, CA 91125, USA
    Cereb Cortex 19:483-95. 2009
  3. pmc States versus rewards: dissociable neural prediction error signals underlying model-based and model-free reinforcement learning
    Jan Gläscher
    Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, CA 91101, USA
    Neuron 66:585-95. 2010
  4. pmc Distributed neural system for general intelligence revealed by lesion mapping
    J Gläscher
    Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, CA 91125, USA
    Proc Natl Acad Sci U S A 107:4705-9. 2010
  5. ncbi request reprint Independent effects of emotion and working memory load on visual activation in the lateral occipital complex
    Jan Gläscher
    Department of Systems Neuroscience, NeuroImage Nord, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany
    J Neurosci 27:4366-73. 2007
  6. doi request reprint Visualization of group inference data in functional neuroimaging
    Jan Gläscher
    California Institute of Technology, Pasadena, 91125, USA
    Neuroinformatics 7:73-82. 2009
  7. ncbi request reprint Dissociable systems for gain- and loss-related value predictions and errors of prediction in the human brain
    Juliana Yacubian
    Department of Systems Neuroscience, NeuroImage Nord, University Medical Center Hamburg Eppendorf, D 20246 Hamburg, Germany
    J Neurosci 26:9530-7. 2006
  8. ncbi request reprint Pathological gambling is linked to reduced activation of the mesolimbic reward system
    Jan Reuter
    NeuroImage Nord, Department of Neurology, Hamburg University Hospital Eppendorf, Martinistr 52, 20246 Hamburg, Germany
    Nat Neurosci 8:147-8. 2005
  9. pmc Lesion mapping of cognitive control and value-based decision making in the prefrontal cortex
    Jan Gläscher
    Division of Humanities and Social Sciences and Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Proc Natl Acad Sci U S A 109:14681-6. 2012
  10. ncbi request reprint Subregions of the ventral striatum show preferential coding of reward magnitude and probability
    Juliana Yacubian
    NeuroImage Nord, Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, Martinistr 52, D 20246, Hamburg, Germany
    Neuroimage 38:557-63. 2007

Detail Information

Publications20

  1. ncbi request reprint Formal learning theory dissociates brain regions with different temporal integration
    Jan Gläscher
    NeuroImage Nord, Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, Martinistrasse 52, D 20246 Hamburg, Germany
    Neuron 47:295-306. 2005
    ....
  2. pmc Determining a role for ventromedial prefrontal cortex in encoding action-based value signals during reward-related decision making
    Jan Gläscher
    Division of Humanities and Social Sciences, California Institute of Technology, MC 114 96, 1200 E California Boulevard, Pasadena, CA 91125, USA
    Cereb Cortex 19:483-95. 2009
    ..These findings suggest that ventromedial prefrontal cortex may play a role in encoding the value of chosen actions irrespective of whether those actions denote physical motor responses or more abstract decision options...
  3. pmc States versus rewards: dissociable neural prediction error signals underlying model-based and model-free reinforcement learning
    Jan Gläscher
    Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, CA 91101, USA
    Neuron 66:585-95. 2010
    ..This finding supports the existence of two unique forms of learning signal in humans, which may form the basis of distinct computational strategies for guiding behavior...
  4. pmc Distributed neural system for general intelligence revealed by lesion mapping
    J Gläscher
    Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, CA 91125, USA
    Proc Natl Acad Sci U S A 107:4705-9. 2010
    ..We suggest that general intelligence draws on connections between regions that integrate verbal, visuospatial, working memory, and executive processes...
  5. ncbi request reprint Independent effects of emotion and working memory load on visual activation in the lateral occipital complex
    Jan Gläscher
    Department of Systems Neuroscience, NeuroImage Nord, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany
    J Neurosci 27:4366-73. 2007
    ..A connectivity analysis suggests that the emotional modulation might originate in the amygdalo-hippocampal junction...
  6. doi request reprint Visualization of group inference data in functional neuroimaging
    Jan Gläscher
    California Institute of Technology, Pasadena, 91125, USA
    Neuroinformatics 7:73-82. 2009
    ..The large variety of plot options renders rfxplot suitable both for data exploration as well as producing high-quality figures for publications...
  7. ncbi request reprint Dissociable systems for gain- and loss-related value predictions and errors of prediction in the human brain
    Juliana Yacubian
    Department of Systems Neuroscience, NeuroImage Nord, University Medical Center Hamburg Eppendorf, D 20246 Hamburg, Germany
    J Neurosci 26:9530-7. 2006
    ..Prevalence of either part might render expectations more positive or negative, which could contribute to the pathophysiology of mood disorders like major depression...
  8. ncbi request reprint Pathological gambling is linked to reduced activation of the mesolimbic reward system
    Jan Reuter
    NeuroImage Nord, Department of Neurology, Hamburg University Hospital Eppendorf, Martinistr 52, 20246 Hamburg, Germany
    Nat Neurosci 8:147-8. 2005
    ....
  9. pmc Lesion mapping of cognitive control and value-based decision making in the prefrontal cortex
    Jan Gläscher
    Division of Humanities and Social Sciences and Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Proc Natl Acad Sci U S A 109:14681-6. 2012
    ..By contrast, regions in the ventral PFC were required for decision-making. These findings provide detailed causal evidence for a remarkable functional-anatomical specificity in the human PFC...
  10. ncbi request reprint Subregions of the ventral striatum show preferential coding of reward magnitude and probability
    Juliana Yacubian
    NeuroImage Nord, Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, Martinistr 52, D 20246, Hamburg, Germany
    Neuroimage 38:557-63. 2007
    ....
  11. ncbi request reprint fMRI reveals how pain modulates visual object processing in the ventral visual stream
    Ulrike Bingel
    NeuroImage Nord, Department of Neurology, University Medical Center Hamburg Eppendorf, Germany
    Neuron 55:157-67. 2007
    ....
  12. doi request reprint Structure-function relationships in the processing of regret in the orbitofrontal cortex
    Tobias Sommer
    Department of Systems Neuroscience, NeuroImage Nord, University of Hamburg Medical School, Bldg S10, Hamburg, Germany
    Brain Struct Funct 213:535-51. 2009
    ..Vice versa, the differential contribution of OFC subregions to these processes also adds evidence to the current debate on the function of this cortical structure in decision-making that attracted increasing attention in recent years...
  13. pmc Personal space regulation by the human amygdala
    Daniel P Kennedy
    Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, California, USA
    Nat Neurosci 12:1226-7. 2009
    ..The amygdala may be required to trigger the strong emotional reactions normally following personal space violations, thus regulating interpersonal distance in humans...
  14. pmc Lesion mapping of cognitive abilities linked to intelligence
    Jan Gläscher
    Division of Humanities and Social Sciences, Caltech, Pasadena, CA 91125, USA
    Neuron 61:681-91. 2009
    ..Our findings provide comprehensive lesion maps of intelligence factors, and make specific recommendations for interpretation and application of the WAIS to the study of intelligence in health and disease...
  15. doi request reprint Emotional enhancement effect of memory: removing the influence of cognitive factors
    Tobias Sommer
    NeuroImage Nord, Department of Systems Neuroscience, University of Hamburg Medical School, Hamburg 20246, Germany
    Learn Mem 15:569-73. 2008
    ..We observed the characteristic neuronal correlates of the EEM, in particular enhanced activity in the amygdala and hippocampus, which provides evidence for an arousal-driven EEM in the amygdala as proposed by the modulation hypothesis...
  16. pmc Gene-gene interaction associated with neural reward sensitivity
    Juliana Yacubian
    NeuroImage Nord, Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Proc Natl Acad Sci U S A 104:8125-30. 2007
    ..In view of a consistent relationship between reduced reward sensitivity and addiction, our findings point to a potential genetic basis for vulnerability to addiction...
  17. pmc Neural dynamics of learning sound-action associations
    Adam McNamara
    NeuroImage Nord, Department of Neurology, UKSH, Luebeck, Germany
    PLoS ONE 3:e3845. 2008
    ....
  18. pmc Elevated responses to constant facial emotions in different faces in the human amygdala: an fMRI study of facial identity and expression
    Jan Gläscher
    NeuroImage Nord, Department of Neurology, University Hospital Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    BMC Neurosci 5:45. 2004
    ....
  19. ncbi request reprint Neural correlates of memory confidence
    Steffen Moritz
    Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
    Neuroimage 33:1188-93. 2006
    ..In contrast, increments in doubt were solely related to activation in the superior posterior parietal cortex. To conclude, the study provides some evidence for dissociable systems for confidence and doubt...
  20. ncbi request reprint Processing of the arousal of subliminal and supraliminal emotional stimuli by the human amygdala
    Jan Gläscher
    NeuroImage Nord, Department of Neurology, University Hospital Hamburg Eppendorf, University of Hamburg, D 20246 Hamburg, Germany
    J Neurosci 23:10274-82. 2003
    ....