S H Dairkee

Summary

Affiliation: California Pacific Medical Center
Country: USA

Publications

  1. ncbi request reprint Oxidative stress pathways highlighted in tumor cell immortalization: association with breast cancer outcome
    S H Dairkee
    California Pacific Medical Center Research Institute, San Francisco, CA 94107, USA
    Oncogene 26:6269-79. 2007
  2. pmc Negative regulation of UCP2 by TGFβ signaling characterizes low and intermediate-grade primary breast cancer
    A Sayeed
    California Pacific Medical Center Research Institute, San Francisco, CA 94107, USA
    Cell Death Dis 1:e53. 2010
  3. ncbi request reprint Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene
    D G Albertson
    1 Cancer Research Institute, University of California, San Francisco, Box 0808, San Francisco, California, USA
    Nat Genet 25:144-6. 2000
  4. pmc A molecular 'signature' of primary breast cancer cultures; patterns resembling tumor tissue
    Shanaz H Dairkee
    California Pacific Medical Center, San Francisco, CA 94115 1932, USA
    BMC Genomics 5:47. 2004
  5. ncbi request reprint Biallelic inactivation of the thyroid hormone receptor beta1 gene in early stage breast cancer
    Zheng Li
    Geraldine Brush Cancer Research Institute, California Pacific Medical Center, San Francisco, California 94115, USA
    Cancer Res 62:1939-43. 2002
  6. pmc Aging impacts transcriptomes but not genomes of hormone-dependent breast cancers
    Christina Yau
    Buck Institute for Age Research, 8001 Redwood Boulevard, Novato, CA 94945, USA
    Breast Cancer Res 9:R59. 2007
  7. ncbi request reprint Genome-wide allelotyping of a new in vitro model system reveals early events in breast cancer progression
    Zheng Li
    Geraldine Brush Cancer Research Institute, California Pacific Medical Center, San Francisco 94115, USA
    Cancer Res 62:5980-7. 2002
  8. ncbi request reprint Differentiation of lobular versus ductal breast carcinomas by expression microarray analysis
    James E Korkola
    Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA 94143 0808, USA
    Cancer Res 63:7167-75. 2003
  9. pmc Enhanced NF kappa B and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer
    Yamei Zhou
    Buck Institute for Age Research, Novato, CA 94945, USA
    BMC Cancer 7:59. 2007
  10. ncbi request reprint Increased risk of local recurrence is associated with allelic loss in normal lobules of breast cancer patients
    Zheng Li
    Geraldine Brush Cancer Research Institute, California Pacific Medical Center, San Francisco, California 94115, USA
    Cancer Res 62:1000-3. 2002

Research Grants

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Oxidative stress pathways highlighted in tumor cell immortalization: association with breast cancer outcome
    S H Dairkee
    California Pacific Medical Center Research Institute, San Francisco, CA 94107, USA
    Oncogene 26:6269-79. 2007
    ..Targeting a subset of aggressive breast cancers by reversing ImmSig components could be a practical therapeutic strategy...
  2. pmc Negative regulation of UCP2 by TGFβ signaling characterizes low and intermediate-grade primary breast cancer
    A Sayeed
    California Pacific Medical Center Research Institute, San Francisco, CA 94107, USA
    Cell Death Dis 1:e53. 2010
    ....
  3. ncbi request reprint Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene
    D G Albertson
    1 Cancer Research Institute, University of California, San Francisco, Box 0808, San Francisco, California, USA
    Nat Genet 25:144-6. 2000
    ..The putative oncogene ZNF217 (ref. 5) mapped to one peak, and CYP24 (encoding vitamin D 24 hydroxylase), whose overexpression is likely to lead to abrogation of growth control mediated by vitamin D, mapped to the other...
  4. pmc A molecular 'signature' of primary breast cancer cultures; patterns resembling tumor tissue
    Shanaz H Dairkee
    California Pacific Medical Center, San Francisco, CA 94115 1932, USA
    BMC Genomics 5:47. 2004
    ..To identify the spectrum of malignant attributes maintained outside the host environment, we have compared global gene expression in primary breast tumors and matched short-term epithelial cultures...
  5. ncbi request reprint Biallelic inactivation of the thyroid hormone receptor beta1 gene in early stage breast cancer
    Zheng Li
    Geraldine Brush Cancer Research Institute, California Pacific Medical Center, San Francisco, California 94115, USA
    Cancer Res 62:1939-43. 2002
    ..The observation of early, frequent, and multiple mechanisms of TRbeta1 inactivation suggests a potential role for this gene in the suppression of breast tumorigenesis...
  6. pmc Aging impacts transcriptomes but not genomes of hormone-dependent breast cancers
    Christina Yau
    Buck Institute for Age Research, 8001 Redwood Boulevard, Novato, CA 94945, USA
    Breast Cancer Res 9:R59. 2007
    ..Except for inherited forms of breast cancer, however, there is little genetic or epigenetic understanding of the biological basis linking aging with sporadic breast cancer incidence and its clinical behavior...
  7. ncbi request reprint Genome-wide allelotyping of a new in vitro model system reveals early events in breast cancer progression
    Zheng Li
    Geraldine Brush Cancer Research Institute, California Pacific Medical Center, San Francisco 94115, USA
    Cancer Res 62:5980-7. 2002
    ....
  8. ncbi request reprint Differentiation of lobular versus ductal breast carcinomas by expression microarray analysis
    James E Korkola
    Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA 94143 0808, USA
    Cancer Res 63:7167-75. 2003
    ..In conclusion, specific changes in gene expression distinguish lobular from ductal breast carcinomas. These genes may be important in understanding the basis of phenotypic differences among breast cancers...
  9. pmc Enhanced NF kappa B and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer
    Yamei Zhou
    Buck Institute for Age Research, Novato, CA 94945, USA
    BMC Cancer 7:59. 2007
    ..Signaling pathways that converge on two different transcription factor complexes, NFkappaB and AP-1, have been identified in estrogen receptor (ER)-positive breast cancers resistant to the antiestrogen, tamoxifen...
  10. ncbi request reprint Increased risk of local recurrence is associated with allelic loss in normal lobules of breast cancer patients
    Zheng Li
    Geraldine Brush Cancer Research Institute, California Pacific Medical Center, San Francisco, California 94115, USA
    Cancer Res 62:1000-3. 2002
    ..These data provide a strong rationale to assess histologically normal breast tissue at the margins of surgically excised cancers for molecular predictors of local recurrence after breast-conserving treatment...
  11. doi request reprint Bisphenol A induces a profile of tumor aggressiveness in high-risk cells from breast cancer patients
    Shanaz H Dairkee
    California Pacific Medical Center Research Institute, San Francisco, CA 94107, USA
    Cancer Res 68:2076-80. 2008
    ....
  12. ncbi request reprint Aberrations of breast cancer susceptibility genes occur early in sporadic breast tumors and in acquisition of breast epithelial immortalization
    Zhen Hang Meng
    California Pacific Medical Center, San Francisco, California 94115, USA
    Genes Chromosomes Cancer 41:214-22. 2004
    ..The intimate role of these genes in DNA repair and their early deletion has implications for the possible transforming effects of DNA-damaging agents on unexcised breast tissue harboring LOHint within breast cancer patients...

Research Grants5

  1. Functional Analysis of Histologic Grade in Breast Cancer
    Shanaz Dairkee; Fiscal Year: 2007
    ..abstract_text> ..
  2. Functional Analysis of Histologic Grade in Breast Cancer
    Shanaz Dairkee; Fiscal Year: 2009
    ..abstract_text> ..