Research Topics
Genomes and Genes
| Suzanne ChengSummaryAffiliation: California Birth Defects Monitoring Program Country: USA Publications
Research Grants
| Collaborators
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Detail Information
Publications
Correlates of postpartum smoking relapse. Results from the Pregnancy Risk Assessment Monitoring System (PRAMS)S L Carmichael
Epidemic Intelligence Service, Epidemiology Program Office, and the Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Am J Prev Med 19:193-6. 2000....- Maternal reproductive and demographic characteristics as risk factors for hypospadiasSuzan L Carmichael
March of Dimes Birth Defect Foundation California Department of Health Services, California Birth Defects Monitoring Program, Berkeley, CA 94710, USA
Paediatr Perinat Epidemiol 21:210-8. 2007..Although the potential contribution of underlying maternal endocrine parameters to the current findings are unknown, the results do provide clues regarding hypospadias aetiology that merit further investigation... 
Maternal stressful life events and risks of birth defectsSuzan L Carmichael
March of Dimes Birth Defect Foundation, California Department of Health Services, California Birth Defects Monitoring Program, Berkeley, CA, USA
Epidemiology 18:356-61. 2007..Several previous studies suggest that maternal stress may be associated with increased risk of certain birth defects. This study examined the association of maternal stressful life events with risks of several birth defects...- Risks of human limb deficiency anomalies associated with 29 SNPs of genes involved in homocysteine metabolism, coagulation, cell-cell interactions, inflammatory response, and blood pressure regulationSuzan L Carmichael
California Birth Defects Monitoring Program, March of Dimes Birth Defects Foundation, Berkeley, California 94710, USA
Am J Med Genet A 140:2433-40. 2006..These results suggest involvement of genetic variation of biologically relevant candidate genes, and gene-environment interaction, for some limb anomalies whose pathogenesis may be related to altered vascular tone or integrity... - Risk of limb deficiency defects associated with NAT1, NAT2, GSTT1, GSTM1, and NOS3 genetic variants, maternal smoking, and vitamin supplement intakeSuzan L Carmichael
March of Dimes Birth Defect Foundation California Department of Health Services, California Birth Defects Monitoring Program, Berkeley, California 94710, USA
Am J Med Genet A 140:1915-22. 2006..Further studies exploring genetic susceptibility and combined gene-environment effects with respect to limb development will be important to continued improvement of our understanding of the etiology of limb anomalies... - Correlates of intake of folic acid-containing supplements among pregnant womenS L Carmichael
March of Dimes Birth Defect Foundation California Department of Health Services, California Birth Defects Monitoring Program, Berkeley, CA, USA
Am J Obstet Gynecol 194:203-10. 2006..This study describes the timing and correlates of folic acid supplement intake among pregnant women... - Hypospadias and maternal exposures to cigarette smokeSuzan L Carmichael
March of Dimes Birth Defect Foundation California Department of Health Services, California Birth Defects Monitoring Program, Berkeley, CA 94710, USA
Paediatr Perinat Epidemiol 19:406-12. 2005..This analysis does not confirm a recent report suggesting that maternal smoking is associated with a reduced risk of having offspring with hypospadias... - Maternal food insecurity is associated with increased risk of certain birth defectsSuzan L Carmichael
March of Dimes Foundation, California Birth Defects Monitoring Program, Berkeley, CA 94710, USA
J Nutr 137:2087-92. 2007..e. 2), the corresponding OR was 1.16 (95% CI 0.96, 1.38). This study suggests that increased risks of certain birth defects may be included among the negative consequences of food insecurity... - Congenital malformations in offspring of Hispanic and African-American women in California, 1989-1997Suzan L Carmichael
March of Dimes Birth Defects Foundation, California Birth Defects Monitoring Program, Berkeley, California 94710, USA
Birth Defects Res A Clin Mol Teratol 70:382-8. 2004..Little is known about risks of most specific birth defects among infants born to U.S.-born and foreign-born Hispanic or African-American women... - Limb deficiency defects, MSX1, and exposure to tobacco smokeSuzan L Carmichael
March of Dimes Birth Defect Foundation California Department of Health Services, California Birth Defects Monitoring Program, Oakland, California 94710, USA
Am J Med Genet A 125:285-9. 2004..This finding contrasts with results of a previous study, which provided initial evidence for such an interaction. Several important methodological differences may have contributed to the differences in findings between the two studies... - Dieting behaviors and risk of neural tube defectsSuzan L Carmichael
March of Dimes Birth Defects Foundation California Department of Health Services, California Birth Defects Monitoring Program, Oakland, CA, USA
Am J Epidemiol 158:1127-31. 2003..7, 95% confidence interval: 0.7, 10.2). This study suggests that maternal dieting behaviors involving restricted food intake during the first trimester may be associated with increased NTD risk... - Physical activity and risk of neural tube defectsSuzan L Carmichael
March of Dimes Birth Defects Foundation California Department of Health Services, Oakland 94606 5226, USA
Matern Child Health J 6:151-7. 2002..Owing to its association with known risk factors for neural tube defects (NTDs) and its impact on physiologic processes relevant to fetal development, physical activity was identified as a potential risk factor for NTD-affected pregnancy... - Timing of prenatal care initiation and risk of congenital malformationsSuzan L Carmichael
March of Dimes Birth Defect Foundation, California Birth Defects Monitoring Program, Oakland, California 94606, USA
Teratology 66:326-30. 2002..This study uses data from a large population-based registry to explore the association of timing of prenatal care initiation with risks of selected congenital malformation phenotypes... - Diet quality and risk of neural tube defectsSuzan L Carmichael
March of Dimes Birth Defects Foundation California Birth Defects Monitoring Program, Oakland 94606, USA
Med Hypotheses 60:351-5. 2003..Stratified analyses suggested that the effect may be restricted to certain groups of women who may be at greater nutritional risk (i.e., women who did not take vitamin supplements or regularly consume breakfast cereals before pregnancy)... - Social networks and risk of neural tube defectsSuzan L Carmichael
March of Dimes Birth Defects Foundation California Department of Health Services, California Birth Defects Monitoring Program, Oakland, CA 94606 5226, USA
Eur J Epidemiol 18:129-33. 2003..This study is the first to investigate the association between social networks and risk of NTDs. Stronger inferences await replication and extension of these results... - Socio-economic status and risk of conotruncal heart defects and orofacial cleftsSuzan L Carmichael
March of Dimes Birth Defects Foundation California Department of Health Services, California Birth Defects Monitoring Program, Oakland, CA 94710, USA
Paediatr Perinat Epidemiol 17:264-71. 2003..4 for dTGA, and ORs for all six measures were < 0.7 for TOF. ORs for clefts tended to be closer to 1. This study suggests that SES risks are birth defect specific... - Hypospadias in California: trends and descriptive epidemiologySuzan L Carmichael
March of Dimes Birth Defect Foundation, California Birth Defects Monitoring Program, Oakland, California, USA
Epidemiology 14:701-6. 2003..We used actively ascertained, population-based data for which detailed clinical descriptions permitted careful phenotypic classifications... - Risks of human conotruncal heart defects associated with 32 single nucleotide polymorphisms of selected cardiovascular disease-related genesGary M Shaw
March of Dimes Birth Defects Foundation, California Birth Defects Monitoring Program, Berkeley 94710, USA
Am J Med Genet A 138:21-6. 2005..In particular, NPPA appears to be a good candidate gene for conotruncal defects and warrants further investigation... - Endothelial nitric oxide synthase (NOS3) genetic variants, maternal smoking, vitamin use, and risk of human orofacial cleftsGary M Shaw
California Birth Defects Monitoring Program, March of Dimes Birth Defects Foundation, Berkeley, CA 94710, USA
Am J Epidemiol 162:1207-14. 2005..6, 95% CI: 2.1, 10.2; for 894T, OR = 4.4, 95% CI: 1.8, 10.7). No similar patterns were observed for risk of cleft palate... - Confirmation of an association between the TNF(-308) promoter polymorphism and stroke risk in children with sickle cell anemiaCarolyn Hoppe
Department of Hematology Oncology, Children s Hospital and Research Center Oakland, Oakland, CA 94609, USA
Stroke 38:2241-6. 2007..The aim of this replication study was to confirm our previous findings of associations between the TNF(-308) G/A, IL4R 503 S/P, and ADRB2 27 Q/E polymorphisms and large vessel stroke risk... - Association between a leukotriene C4 synthase gene promoter polymorphism and coronary artery calcium in young women: the Muscatine StudyDavid M Iovannisci
Childrens s Hospital and Research Center Oakland, CA, USA
Arterioscler Thromb Vasc Biol 27:394-9. 2007..If risk factors can be identified earlier in life, such as genetic variation, preventive measures may be taken before overt symptoms of pathology have manifested, and when treatments may be most effective... - Candidate gene polymorphism in cardiovascular disease: the BIP cohortEsther Leshinsky-Silver
Molecular Genetics Laboratory, Alameda, California, USA
Isr Med Assoc J 8:103-5. 2006..This cohort has the data for the lipid profile of each individual, fibrinogen, insulin, as well as clinical, demographic and lifestyle parameters... - Gene interactions and stroke risk in children with sickle cell anemiaCarolyn Hoppe
Department of Hematology Oncology, Children s Hospital and Research Center at Oakland, 747 52nd St, Oakland, CA 94609, USA
Blood 103:2391-6. 2004..If confirmed, these results provide a basis for population screening and targeted intervention to prevent stroke in SCA...
Research Grants
- Exogenous Stressors and Birth Defects RisksSuzan Carmichael; Fiscal Year: 2005..This research will enhance scientific understanding of the causes of several common, costly, often deadly birth defects, which will undoubtedly have important implications for their risk assessment and prevention. ..