M J Chen

Summary

Affiliation: California State University
Country: USA

Publications

  1. ncbi Criterion-related validity of the Borg ratings of perceived exertion scale in healthy individuals: a meta-analysis
    Michael J Chen
    Department of Biological Sciences, California State University, Los Angeles 90032, USA
    J Sports Sci 20:873-99. 2002
  2. ncbi Running exercise-induced up-regulation of hippocampal brain-derived neurotrophic factor is CREB-dependent
    Michael J Chen
    Department of Biological Sciences, California State University, 5151 State University Dr, Los Angeles, CA 90032, USA
    Hippocampus 19:962-72. 2009
  3. ncbi Running exercise- and antidepressant-induced increases in growth and survival-associated signaling molecules are IGF-dependent
    Michael J Chen
    Department of Biological Sciences, California State University, 5151 State University Drive, Los Angeles, CA 90032, USA
    Growth Factors 25:118-31. 2007
  4. ncbi Exercise activates the phosphatidylinositol 3-kinase pathway
    Michael J Chen
    Department of Biological Sciences, California State University, Los Angeles, 5151 State University Drive, Los Angeles, CA 90032, USA
    Brain Res Mol Brain Res 135:181-93. 2005
  5. ncbi Norepinephrine induces BDNF and activates the PI-3K and MAPK cascades in embryonic hippocampal neurons
    M J Chen
    California State University, Los Angeles, Department of Biological Sciences, 5151 State University Dr, Los Angeles, CA 90032, USA
    Cell Signal 19:114-28. 2007
  6. ncbi Nitric oxide synthesis is required for exercise-induced increases in hippocampal BDNF and phosphatidylinositol 3' kinase expression
    Michael J Chen
    Department of Biological Sciences, California State University, 5151 State University Drive, Los Angeles, 90032, USA
    Brain Res Bull 68:257-68. 2006
  7. ncbi Noradrenergic and serotonergic blockade inhibits BDNF mRNA activation following exercise and antidepressant
    A S Ivy
    Department of Biological Sciences, California State University Los Angeles, 5151 State University Drive, Los Angeles, CA 90032, USA
    Pharmacol Biochem Behav 75:81-8. 2003
  8. ncbi The influence of specific noradrenergic and serotonergic lesions on the expression of hippocampal brain-derived neurotrophic factor transcripts following voluntary physical activity
    C Garcia
    Department of Biological Sciences, California State University, 5151 State University Drive, 90032, Los Angeles, CA, USA
    Neuroscience 119:721-32. 2003
  9. ncbi Norepinephrine and nitric oxide promote cell survival signaling in hippocampal neurons
    Neha J Patel
    Department of Biological Sciences, California State University, Los Angeles, 5151 State University Dr, Los Angeles, CA 90032, USA
    Eur J Pharmacol 633:1-9. 2010
  10. ncbi Exercise, antidepressant treatment, and BDNF mRNA expression in the aging brain
    Antonio A Garza
    Department of Biological Sciences, California State University-Los Angeles, 5151 State University Drive, Los Angeles, CA 90032, USA
    Pharmacol Biochem Behav 77:209-20. 2004

Collaborators

Detail Information

Publications15

  1. ncbi Criterion-related validity of the Borg ratings of perceived exertion scale in healthy individuals: a meta-analysis
    Michael J Chen
    Department of Biological Sciences, California State University, Los Angeles 90032, USA
    J Sports Sci 20:873-99. 2002
    ..These findings suggest that although Borg's RPE scale has been shown to be a valid measure of exercise intensity, its validity may not be as high as previously thought (r = 0.80-0.90), except under certain conditions...
  2. ncbi Running exercise-induced up-regulation of hippocampal brain-derived neurotrophic factor is CREB-dependent
    Michael J Chen
    Department of Biological Sciences, California State University, 5151 State University Dr, Los Angeles, CA 90032, USA
    Hippocampus 19:962-72. 2009
    ..Increases in BDNF and phospho-Akt were also prevented when mutant mice received a combination of exercise and antidepressant treatment. The results are discussed in the context of what is currently known about BDNF signaling...
  3. ncbi Running exercise- and antidepressant-induced increases in growth and survival-associated signaling molecules are IGF-dependent
    Michael J Chen
    Department of Biological Sciences, California State University, 5151 State University Drive, Los Angeles, CA 90032, USA
    Growth Factors 25:118-31. 2007
    ....
  4. ncbi Exercise activates the phosphatidylinositol 3-kinase pathway
    Michael J Chen
    Department of Biological Sciences, California State University, Los Angeles, 5151 State University Drive, Los Angeles, CA 90032, USA
    Brain Res Mol Brain Res 135:181-93. 2005
    ..These results suggest that the exercise-induced expression of BDNF is associated with the increased expression of several key intermediates of the PI-3 kinase/Akt pathway, which is known for its role in enhancing neuronal survival...
  5. ncbi Norepinephrine induces BDNF and activates the PI-3K and MAPK cascades in embryonic hippocampal neurons
    M J Chen
    California State University, Los Angeles, Department of Biological Sciences, 5151 State University Dr, Los Angeles, CA 90032, USA
    Cell Signal 19:114-28. 2007
    ....
  6. ncbi Nitric oxide synthesis is required for exercise-induced increases in hippocampal BDNF and phosphatidylinositol 3' kinase expression
    Michael J Chen
    Department of Biological Sciences, California State University, 5151 State University Drive, Los Angeles, 90032, USA
    Brain Res Bull 68:257-68. 2006
    ..These findings further demonstrate the potential therapeutic potential of chronic exercise to supplement pharmacotherapeutic treatment of mood disorders...
  7. ncbi Noradrenergic and serotonergic blockade inhibits BDNF mRNA activation following exercise and antidepressant
    A S Ivy
    Department of Biological Sciences, California State University Los Angeles, 5151 State University Drive, Los Angeles, CA 90032, USA
    Pharmacol Biochem Behav 75:81-8. 2003
    ..5-HT(1A) and 5-HT(2A/C) activation, on the other hand, appear to be most important for antidepressant-induced BDNF regulation, but may also participate significantly in exercise-induced regulation in the CA4...
  8. ncbi The influence of specific noradrenergic and serotonergic lesions on the expression of hippocampal brain-derived neurotrophic factor transcripts following voluntary physical activity
    C Garcia
    Department of Biological Sciences, California State University, 5151 State University Drive, 90032, Los Angeles, CA, USA
    Neuroscience 119:721-32. 2003
    ..Elevations of other exons, such as II and III, may require the activation of separate neurotransmitter systems and intracellular pathways...
  9. ncbi Norepinephrine and nitric oxide promote cell survival signaling in hippocampal neurons
    Neha J Patel
    Department of Biological Sciences, California State University, Los Angeles, 5151 State University Dr, Los Angeles, CA 90032, USA
    Eur J Pharmacol 633:1-9. 2010
    ..These results indicate that pharmacological intervention can promote neuroprotection and survival signaling in the face of nutrient withdrawal, but that this may require that several pathways remain intact...
  10. ncbi Exercise, antidepressant treatment, and BDNF mRNA expression in the aging brain
    Antonio A Garza
    Department of Biological Sciences, California State University-Los Angeles, 5151 State University Drive, Los Angeles, CA 90032, USA
    Pharmacol Biochem Behav 77:209-20. 2004
    ..Our results indicate that the aged brain is responsive to exercise and antidepressant treatment, and changes in regional response patterns may reflect shifts in hippocampal physiology during the lifespan...
  11. ncbi Brain-derived neurotrophic factor and antidepressant activity
    A A Russo-Neustadt
    Department of Biological Sciences, California State University, Los Angeles, CA 90032, USA
    Curr Pharm Des 11:1495-510. 2005
    ....
  12. ncbi Hippocampal brain-derived neurotrophic factor expression following treatment with reboxetine, citalopram, and physical exercise
    Amelia A Russo-Neustadt
    Department of Biological Sciences, California State University, Los Angeles, CA 90032, USA
    Neuropsychopharmacology 29:2189-99. 2004
    ..The serotonergic agent, citalopram, appeared to require longer treatment intervals in order to influence BDNF expression positively...
  13. ncbi Nitric oxide signaling participates in norepinephrine-induced activity of neuronal intracellular survival pathways
    Michael J Chen
    Department of Biological Sciences, California State University, 5151 State University Drive, Los Angeles, CA 90032, USA
    Life Sci 81:1280-90. 2007
    ..This is the first study of its kind demonstrating the involvement of NE-induced pro-survival signaling in three distinct signaling pathways: PI-3K, MAPK, and NO/cGMP. Possible mechanisms are discussed in light of the results...
  14. ncbi Exercise reverses chronic stress-induced Bax oligomer formation in the cerebral cortex
    Danielle Haack
    Department of Biological Sciences, California State University, Los Angeles, CA 90032, USA
    Neurosci Lett 438:290-4. 2008
    ....
  15. ncbi Runx1 function in hematopoiesis is required in cells that express Tek
    Zhe Li
    Department of Biochemistry, Dartmouth Medical School, Hanover, NH 03755, USA
    Blood 107:106-10. 2006
    ..Most embryos died between E12.5 and E13.5 with a phenotype almost identical to Runx1 deficiency. We conclude that Runx1 function in establishing definitive hematopoiesis is required in a Tek+ cell...