Research Topics
| M BonaciniSummaryAffiliation: California Pacific Medical Center Country: USA Publications
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Publications
Intrahepatic lymphocyte phenotypes in hepatitis C virus infection: a comparison between cirrhotic and non-cirrhotic liversM Bonacini
Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
Minerva Gastroenterol Dietol 53:1-7. 2007..The aim of this study was to evaluate the frequency of intrahepatic mononuclear cell phenotypes in patients with chronic HCV. Another aim was to assess the relationship of nonparenchymal cells with liver fibrosis...
Alcohol use among patients with HIV infectionMaurizio Bonacini
Department of Transplantation, California Pacific Medical Center, San Francisco CA 94115, USA
Ann Hepatol 10:502-7. 2011..To evaluate alcohol use in patients with HIV infection, assess ethnic and social associations, and describe outcomes...
Diagnosis and management of cirrhosis in coinfected patientsMaurizio Bonacini
Department of Medicine, University of California at San Francisco, School of Medicine, USA
J Acquir Immune Defic Syndr 45:S38-46; discussion S66-7. 2007..Liver transplantation is feasible in patients with HIV infection, and early evaluation for this option is crucial because of the accelerated course of complications in HIV coinfection...
Survival in patients with HIV infection and viral hepatitis B or C: a cohort studyMaurizio Bonacini
Department of Medicine, University of Southern California School of Medicine, Los Angeles, California, USA
AIDS 18:2039-45. 2004..To assess survival in patients with HIV and viral hepatitis co-infection...
Liver injury during highly active antiretroviral therapy: the effect of hepatitis C coinfectionMaurizio Bonacini
Department of Transplantation, California Pacific Medical Center, San Francisco, CA, USA
Clin Infect Dis 38:S104-8. 2004..Patients with HIV/HCV coinfection should not be denied HAART. Instead, they should be followed-up with monthly liver function tests and referred to specialists if grade 3 or 4 liver enzyme elevations occur...
Chronic hepatitis C in ethnic minority patients evaluated in Los Angeles CountyM Bonacini
Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, USA
Am J Gastroenterol 96:2438-41. 2001..Asians, Latinas, and African Americans are less likely to report injection drug use as a risk factor for hepatitis C virus. Latinos seem to have faster liver fibrosis progression rates than either African Americans or whites...
Effect of coexisting HIV-1 infection on the diagnosis and evaluation of hepatitis C virusM Bonacini
Keck School of Medicine, University of Southern California, Los Angeles, 90033, USA
J Acquir Immune Defic Syndr 26:340-4. 2001..To evaluate the diagnostic accuracy of the test for antibodies to hepatitis C virus by enzyme-linked immunosorbent assay (anti-HCV ELISA-2) in patients with and without HIV-1 infection...
Do type and duration of antiretroviral therapy attenuate liver fibrosis in HIV-hepatitis C virus-coinfected patients?Sumita Verma
Division of Gastrointestinal and Liver Diseases, University of Southern California, Los Angeles, CA 90033, USA
Clin Infect Dis 42:262-70. 2006..This study aimed to determine whether type and duration of therapy for human immunodeficiency virus (HIV) infection attenuates liver fibrosis in patients with HIV and hepatitis C virus (HCV) coinfection...
Therapy of hepatitis C in patients with HIV infectionTami Daugherty
California Pacific Medical Center, 2340 Clay Street, 2nd Floor, San Francisco, CA 94115, USA
Expert Rev Anti Infect Ther 3:375-84. 2005....
Management issues in patients coinfected with hepatitis C virus and HIVMaurizio Bonacini
Division of Gastroenterology and Liver Diseases, Keck School of Medicine, University of Southern California, Los Angeles, USA
AIDS Read 12:19-21, 24-6. 2002..In addition, agents used to treat hepatitis C may lower CD4+ cell counts and hemoglobin levels. Long-acting interferons offer the promise of better sustained HCV response in HIV-HCV coinfection...
Liver disease and HIV. Hepatitis is an ongoing threatDebra Johnson
University of Southern California, Los Angeles, USA
Adv Nurse Pract 11:63-6, 68, 70. 2003
Pathogenesis of hepatitis C virus infectionM Kohla
Department of Transplantation, California Pacific Medical Center, San Francisco, CA 94115, USA
Minerva Gastroenterol Dietol 52:107-23. 2006..Of these factors, age, gender, race and alcohol use are the most established ones. The development of hepatocellular carcinoma is mainly restricted to patients with cirrhosis...
Esophageal disease in patients with AIDS: diagnosis and treatmentM Bonacini
Division of Gastrointestinal and Liver Diseases, University of Southern California School of Medicine, Los Angeles, California, USA
Gastrointest Endosc Clin N Am 8:811-23. 1998..Such short survival may be explained by the underlying immunosuppression, as well as a decrease in nutritional intake due to difficulty swallowing...
Jaundice and hepatocellular damage associated with nevirapine therapyM Prakash
Division of Infectious Diseases, Keck School of Medicine, Los Angeles, California, USA
Am J Gastroenterol 96:1571-4. 2001..No patient was rechallenged with the drug. CONCLUSION: Nevirapine can be associated with icteric hepatitis, which appears to be reversible after withdrawal of the drug...
Highly active antiretroviral therapy-induced liver injuryIra Inductivo-Yu
International Hepatology Scholar Program, California Pacific Medical Center, San Francisco, California 94115, USA
Curr Drug Saf 3:4-13. 2008..Once diagnosed, management generally involves discontinuation of the offending drug(s). A number of studies in progress are investigating whether treatment of hepatitis co-infection can improve the tolerability of HAART...
Hepatitis C in a Los Angeles public hepatitis clinic: demographic and biochemical differences associated with race-ethnicityAnne F Celona
Keck School of Medicine, University of Southern California, Los Angeles, California 94115, USA
Clin Gastroenterol Hepatol 2:459-62. 2004..Further studies are required to determine the possible causes for these biochemical differences...
Mycophenolate mofetil in autoimmune hepatitis patients not responsive or intolerant to standard immunosuppressive therapyIra Inductivo Yu
Division of Hepatology and Complex GI, Physicians Foundation, Department of Transplantation, California Pacific Medical Center, San Francisco, California, USA
Clin Gastroenterol Hepatol 5:799-802. 2007..The aim of this study was to assess the biochemical, histologic, and hematologic parameters during mycophenolate mofetil (MMF) treatment in AIH patients who did not respond to or were intolerant of prednisone and/or azathioprine...
Treatment of chronic hepatitis C in HIV/HCV-coinfection with interferon alpha-2b+ full-course vs. 16-week delayed ribavirinNorbert Brau
Bronx Veterans Affairs Medical Center, Bronx, NY, USA
Hepatology 39:989-98. 2004..Control of HIV infection improves rather than worsens during therapy...
Fulminant hepatitis B due to a lamivudine-resistant mutant of HBV in a patient coinfected with HIVMaurizio Bonacini
Gastroenterology 122:244-5. 2002
Care of patients with chronic hepatitis B and HIV co-infection: recommendations from an HIV-HBV International PanelVincent Soriano
Department of Infectious Diseases, Hospital Carlos III, Calle Sinesio Delgado 10, 28029 Madrid, Spain
AIDS 19:221-40. 2005
Presentation and outcome of hepatocellular carcinoma in HIV-infected patients: a U.S.-Canadian multicenter studyNorbert Brau
Bronx Veterans Affairs VA Medical Center, Infectious Disease Section 111F, 130 West Kingsbridge Road, Bronx, NY 10468, USA
J Hepatol 47:527-37. 2007..HIV-infected patients now live longer and often have complications of liver disease, especially with hepatitis B or C virus coinfection. Limited data are available on those with hepatocellular carcinoma (HCC)...
Factors associated with seronegative chronic hepatitis C virus infection in HIV infectionGabriel Chamie
Department of Medicine, University of California, San Francisco, CA, USA
Clin Infect Dis 44:577-83. 2007..However, associated factors are not well established because of the small number of reported cases...
More advanced hepatic fibrosis in hispanics with chronic hepatitis C infection: role of patient demographics, hepatic necroinflammation, and steatosisSumita Verma
Division of Gastrointestinal and Liver Diseases, Hepatitis Research and Treatment Center, Los Angeles, California, USA
Am J Gastroenterol 101:1817-23. 2006..CONCLUSION: This study confirms that Hispanics have more advanced hepatic fibrosis than NHW. This is related to older age, higher NI grade, and greater prevalence of hepatic steatosis and DM...
Simple clinical variables predict liver histology in hepatitis C: prospective validation of a clinical prediction modelJoseph Romagnuolo
Digestive Disease Center, University of South Carolina, 96 Jonathon Lucas Street, PO Box 250 327, Charleston, SC 29425, USA
Scand J Gastroenterol 40:1365-71. 2005..Absence of predictors also predicted a lack of inflammation and fibrosis. Our aim was prospectively to validate this clinical prediction model using an independent multicenter sample...
Methotrexate (MTX) plus ursodeoxycholic acid (UDCA) in the treatment of primary biliary cirrhosisBurton Combes
The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9151, USA
Hepatology 42:1184-93. 2005..In conclusion, methotrexate when added to UDCA for a median period of 7.6 years had no effect on the course of PBC treated with UDCA alone...
Liver and AIDS mortality in HIV-infected patientsMaurizio Bonacini
J Hepatol 43:911-2; author reply 912. 2005
