Research Topics
| S S ArnonSummaryAffiliation: California Environmental Protection Agency Country: USA Publications
| Collaborators
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Detail Information
Publications
Dual toxin-producing strain of Clostridium botulinum type Bf isolated from a California patient with infant botulismJason R Barash
Infant Botulism Treatment and Prevention Program, California Department of Health Services, Richmond, California 94804, USA
J Clin Microbiol 42:1713-5. 2004..This unique strain represented 0.12% of the California infant botulism case isolates from 1976 to 2003. The relative concentrations of type B and F toxins produced were temperature dependent...
Human botulism immune globulin for the treatment of infant botulismStephen S Arnon
Infant Botulism Treatment and Prevention Program, California Department of Health Services, Richmond, CA 94804, USA
N Engl J Med 354:462-71. 2006..We created the orphan drug Human Botulism Immune Globulin Intravenous (Human) (BIG-IV), which neutralizes botulinum toxin, and evaluated its safety and efficacy in treating infant botulism, the intestinal-toxemia form of human botulism...
Creation and development of the public service orphan drug Human Botulism Immune GlobulinStephen S Arnon
Infant Botulism Treatment and Prevention Program, California Department of Health Services, 850 Marina Bay Pkwy, Room E 361, Richmond, CA 94804, USA
Pediatrics 119:785-9. 2007..To provide a possible paradigm for others, the circumstances that enabled a state public health department to create, test, license, and distribute an orphan drug are described here...
Clinical mimics of infant botulismAnn Marie O Francisco
Infant Botulism Treatment and Prevention Program, California Department of Health Services, 850 Marina Bay Pkwy, Room E 361, Richmond, CA 94804, USA
Pediatrics 119:826-8. 2007....
Botulinum toxin as a biological weapon: medical and public health managementS S Arnon
Infant Botulism Treatment and Prevention Program, California Department of Health Services, 2151 Berkeley Way, Room 506, Berkeley, CA 94704, USA
JAMA 285:1059-70. 2001..The Working Group on Civilian Biodefense has developed consensus-based recommendations for measures to be taken by medical and public health professionals if botulinum toxin is used as a biological weapon against a civilian population...
Novel structural elements within the nonproteolytic clostridium botulinum type F toxin gene clusterN Dover
Infant Botulism Treatment and Prevention Program, California Department of Public Health, 850 Marina Bay Parkway, Room E361, Richmond, CA 94804, USA
Appl Environ Microbiol 77:1904-6. 2011..The neurotoxin gene cluster contained a novel gene arrangement that, compared to other C. botulinum neurotoxin gene clusters, lacked the regulatory botR gene and contained an intergenic is element between its orfX2 and orfX3 genes...
First case of infant botulism caused by Clostridium baratii type F in CaliforniaJason R Barash
Infant Botulism Treatment and Prevention Program, California Department of Health Services, 850 Marina Bay Parkway, Room E-361, Richmond, CA 94804, USA
J Clin Microbiol 43:4280-2. 2005..Environmental investigations failed to identify a source of this strain. This is the youngest patient reported to have infant botulism and the fifth instance of infant botulism caused by C. baratii type F...
Global occurrence of infant botulism, 1976-2006Ruth Koepke
California Department of Public Health, 850 Marina Bay Pkwy, Room E 361, Richmond, CA 94804, USA
Pediatrics 122:e73-82. 2008..To summarize the worldwide occurrence of reported infant (intestinal toxemia) botulism cases since first recognition of the disease in 1976...
Presence of soil-dwelling clostridia in commercial powdered infant formulasJason R Barash
Infant Botulism Treatment and Prevention Program, Division of Communicable Disease Control, Center for Infectious Diseases, California Department of Public Health, Richmond, CA 94804, USA
J Pediatr 156:402-8. 2010....
Infant botulism acquired from household dust presenting as sudden infant death syndromeMari Nevas
Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, P O Box 66, 00014 Helsinki University, Finland
J Clin Microbiol 43:511-3. 2005....
Attomolar detection of botulinum toxin type A in complex biological matricesKarine Bagramyan
Immunology Division, Beckman Research Institute of the City of Hope, Duarte, California, United States of America
PLoS ONE 3:e2041. 2008....
