Ralph Adolphs

Summary

Affiliation: California Institute of Technology
Country: USA

Publications

  1. doi request reprint Social cognition: feeling voices to recognize emotions
    Ralph Adolphs
    Division of Humanities and Social Science and Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Curr Biol 20:R1071-2. 2010
  2. pmc Conceptual challenges and directions for social neuroscience
    Ralph Adolphs
    California Institute of Technology, Pasadena, CA 91125, USA
    Neuron 65:752-67. 2010
  3. pmc The social brain: neural basis of social knowledge
    Ralph Adolphs
    California Institute of Technology Caltech, Pasadena, California 91125, USA
    Annu Rev Psychol 60:693-716. 2009
  4. pmc Lesion mapping of cognitive control and value-based decision making in the prefrontal cortex
    Jan Gläscher
    Division of Humanities and Social Sciences and Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Proc Natl Acad Sci U S A 109:14681-6. 2012
  5. pmc Intact rapid detection of fearful faces in the absence of the amygdala
    Naotsugu Tsuchiya
    Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, California, USA
    Nat Neurosci 12:1224-5. 2009
  6. pmc Anterior prefrontal cortex contributes to action selection through tracking of recent reward trends
    Christopher K Kovach
    Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, California 91125, USA
    J Neurosci 32:8434-42. 2012
  7. pmc Personal space regulation by the human amygdala
    Daniel P Kennedy
    Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, California, USA
    Nat Neurosci 12:1226-7. 2009
  8. ncbi request reprint Social equality in the number of choice options is represented in the ventromedial prefrontal cortex
    Ryuta Aoki
    Tamagawa University Brain Science Institute, 6 1 1, Tamagawa gakuen, Machida, Tokyo 194 8610, Japan, Japan Society for the Promotion of Science, 5 3 1, Koji machi, Chiyoda ku, Tokyo 102 8471, Japan, Division of the Humanities and Social Sciences, California Institute of Technology, Pasadena, California 91125, Department of Psychology, University of California Los Angeles, Los Angeles, California 90095, and Department of Cognitive and Behavioral Science, University of Tokyo, 3 8 1, Komaba, Meguro ku, Tokyo 153 8902, Japan
    J Neurosci 34:6413-21. 2014
  9. pmc Social and monetary reward learning engage overlapping neural substrates
    Alice Lin
    California Institute of Technology, Computations and Neural Systems, MC 136 93 Pasadena, CA 91125 7700, USA
    Soc Cogn Affect Neurosci 7:274-81. 2012
  10. pmc A category-specific response to animals in the right human amygdala
    Florian Mormann
    Division of Biology, California Institute of Technology, Pasadena, California, USA
    Nat Neurosci 14:1247-9. 2011

Detail Information

Publications49

  1. doi request reprint Social cognition: feeling voices to recognize emotions
    Ralph Adolphs
    Division of Humanities and Social Science and Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Curr Biol 20:R1071-2. 2010
    ....
  2. pmc Conceptual challenges and directions for social neuroscience
    Ralph Adolphs
    California Institute of Technology, Pasadena, CA 91125, USA
    Neuron 65:752-67. 2010
    ..It may well be that social neuroscience in the near future will give us an entirely new view of who we are, how we evolved, and what might be in store for the future of our species...
  3. pmc The social brain: neural basis of social knowledge
    Ralph Adolphs
    California Institute of Technology Caltech, Pasadena, California 91125, USA
    Annu Rev Psychol 60:693-716. 2009
    ..Here I provide a broad survey of the key abilities, processes, and ways in which to relate these to data from cognitive neuroscience...
  4. pmc Lesion mapping of cognitive control and value-based decision making in the prefrontal cortex
    Jan Gläscher
    Division of Humanities and Social Sciences and Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Proc Natl Acad Sci U S A 109:14681-6. 2012
    ..By contrast, regions in the ventral PFC were required for decision-making. These findings provide detailed causal evidence for a remarkable functional-anatomical specificity in the human PFC...
  5. pmc Intact rapid detection of fearful faces in the absence of the amygdala
    Naotsugu Tsuchiya
    Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, California, USA
    Nat Neurosci 12:1224-5. 2009
    ..We conclude that the amygdala is not essential for early stages of fear processing but, instead, modulates recognition and social judgment...
  6. pmc Anterior prefrontal cortex contributes to action selection through tracking of recent reward trends
    Christopher K Kovach
    Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, California 91125, USA
    J Neurosci 32:8434-42. 2012
    ....
  7. pmc Personal space regulation by the human amygdala
    Daniel P Kennedy
    Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, California, USA
    Nat Neurosci 12:1226-7. 2009
    ..The amygdala may be required to trigger the strong emotional reactions normally following personal space violations, thus regulating interpersonal distance in humans...
  8. ncbi request reprint Social equality in the number of choice options is represented in the ventromedial prefrontal cortex
    Ryuta Aoki
    Tamagawa University Brain Science Institute, 6 1 1, Tamagawa gakuen, Machida, Tokyo 194 8610, Japan, Japan Society for the Promotion of Science, 5 3 1, Koji machi, Chiyoda ku, Tokyo 102 8471, Japan, Division of the Humanities and Social Sciences, California Institute of Technology, Pasadena, California 91125, Department of Psychology, University of California Los Angeles, Los Angeles, California 90095, and Department of Cognitive and Behavioral Science, University of Tokyo, 3 8 1, Komaba, Meguro ku, Tokyo 153 8902, Japan
    J Neurosci 34:6413-21. 2014
    ..These findings may provide valuable insight into the human ability to value equal opportunity, a characteristic long emphasized in politics, economics, and philosophy. ..
  9. pmc Social and monetary reward learning engage overlapping neural substrates
    Alice Lin
    California Institute of Technology, Computations and Neural Systems, MC 136 93 Pasadena, CA 91125 7700, USA
    Soc Cogn Affect Neurosci 7:274-81. 2012
    ..Taken together, the findings support the hypothesis that shared anatomical substrates are involved in the computation of both monetary and social rewards...
  10. pmc A category-specific response to animals in the right human amygdala
    Florian Mormann
    Division of Biology, California Institute of Technology, Pasadena, California, USA
    Nat Neurosci 14:1247-9. 2011
    ..This selectivity appeared to be independent of emotional valence or arousal and may reflect the importance that animals held throughout our evolutionary past...
  11. pmc Lesion mapping of cognitive abilities linked to intelligence
    Jan Gläscher
    Division of Humanities and Social Sciences, Caltech, Pasadena, CA 91125, USA
    Neuron 61:681-91. 2009
    ..Our findings provide comprehensive lesion maps of intelligence factors, and make specific recommendations for interpretation and application of the WAIS to the study of intelligence in health and disease...
  12. pmc Economic games quantify diminished sense of guilt in patients with damage to the prefrontal cortex
    Ian Krajbich
    Division of the Humanities and Social Sciences, California Institute of Technology, Pasadena, California 91125, USA
    J Neurosci 29:2188-92. 2009
    ..Instead, the findings argue for a specific insensitivity to guilt, an abnormality that we suggest characterizes a key contribution made by the VMPFC to social behavior...
  13. ncbi request reprint Looking at other people: mechanisms for social perception revealed in subjects with focal amygdala damage
    Ralph Adolphs
    Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, CA 91125, USA
    Novartis Found Symp 278:146-59; discussion 160-4, 216-21. 2007
    ..Ongoing studies in our laboratory examine face-to-face social interactions with real people in an attempt to link the above impairments in the laboratory to the dysfunctional social cognition seen in everyday life...
  14. pmc Single-neuron correlates of atypical face processing in autism
    Ueli Rutishauser
    Department of Neurosurgery, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA Department of Neurology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA Computation and Neural Systems Program, California Institute of Technology, Pasadena, CA 91125, USA Electronic address
    Neuron 80:887-99. 2013
    ....
  15. ncbi request reprint Role of the amygdala in processing visual social stimuli
    Ralph Adolphs
    Division of the Humanities and Social Sciences, HSS 228 77, California Institute of Technology, Pasadena, CA 91125, USA
    Prog Brain Res 156:363-78. 2006
    ..Finally, we argue that the term emotion be broadened to include increased attention to bodily responses and their representation in cortex...
  16. pmc Impaired fixation to eyes following amygdala damage arises from abnormal bottom-up attention
    Daniel P Kennedy
    Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, CA 91125, USA
    Neuropsychologia 48:3392-8. 2010
    ....
  17. pmc Insensitivity to social reputation in autism
    Keise Izuma
    Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, CA 91125, USA
    Proc Natl Acad Sci U S A 108:17302-7. 2011
    ..The results argue that people with autism lack the ability to take into consideration what others think of them and provide further support for specialized neural systems mediating the effects of social reputation...
  18. pmc Distinct face-processing strategies in parents of autistic children
    Ralph Adolphs
    California Institute of Technology, Pasadena, California 91125, USA
    Curr Biol 18:1090-3. 2008
    ....
  19. pmc The behavioral and neural mechanisms underlying the tracking of expertise
    Erie D Boorman
    Department of Humanities and Social Sciences, California Institute of Technology, Pasadena, CA 91125, USA Computation and Neural Systems, California Institute of Technology, Pasadena, CA 91125, USA Centre for Functional Magnetic Resonance Imaging of the Brain, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK Electronic address
    Neuron 80:1558-71. 2013
    ..Moreover, activity in lateral orbitofrontal and medial prefrontal cortex reflected behavioral differences in learning about people and algorithms. These findings provide basic insights into the neural basis of social learning. ..
  20. pmc Social manipulation of preference in the human brain
    Keise Izuma
    Division of Humanities and Social Sciences, California Institute of Technology, 1200 E California Boulevard, Pasadena, CA 91125, USA
    Neuron 78:563-73. 2013
    ..A single social encounter can thus result in long-lasting preference change, a mechanism that recruits dmPFC and that may reflect the aversive nature of cognitive imbalance...
  21. ncbi request reprint Abnormal use of facial information in high-functioning autism
    Michael L Spezio
    Division of Humanities and Social Sciences, 228 77, California Institute of Technology, Caltech, Pasadena, CA 91125, USA
    J Autism Dev Disord 37:929-39. 2007
    ..These findings provide a novel quantitative assessment of how people with autism utilize information in faces when making social judgments...
  22. ncbi request reprint Contributions of the amygdala to reward expectancy and choice signals in human prefrontal cortex
    Alan N Hampton
    Computation and Neural Systems Program, California Institute of Technology, Pasadena, CA 91125, USA
    Neuron 55:545-55. 2007
    ..These findings support a critical role for the human amygdala in establishing expected reward representations in PFC, which in turn may be used to guide behavioral choice...
  23. pmc Perception of emotions from facial expressions in high-functioning adults with autism
    Daniel P Kennedy
    Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, CA, USA
    Neuropsychologia 50:3313-9. 2012
    ..We thus demonstrate a subtle but specific pattern of impairments in facial emotion perception in people with autism...
  24. pmc The social brain in psychiatric and neurological disorders
    Daniel P Kennedy
    California Institute of Technology, 1200 E California Blvd, HSS 228 77, Caltech, Pasadena, CA 91125, USA
    Trends Cogn Sci 16:559-72. 2012
    ..We suggest that the social brain, and its dysfunction and recovery, must be understood not in terms of specific structures, but rather in terms of their interaction in large-scale networks...
  25. pmc Perspective distortion from interpersonal distance is an implicit visual cue for social judgments of faces
    Ronnie Bryan
    Computation and Neural Systems Program, California Institute of Technology, Pasadena, California, United States of America
    PLoS ONE 7:e45301. 2012
    ..These results demonstrate a novel facial cue influencing a range of social judgments as a function of interpersonal distance, an effect that may be processed implicitly...
  26. pmc Fear, faces, and the human amygdala
    Ralph Adolphs
    Caltech, Pasadena, CA 91125, USA
    Curr Opin Neurobiol 18:166-72. 2008
    ..A large current research effort extends the amygdala's putative role to a number of psychiatric illnesses...
  27. pmc What does the amygdala contribute to social cognition?
    Ralph Adolphs
    California Institute of Technology, Pasadena, California 91125, USA
    Ann N Y Acad Sci 1191:42-61. 2010
    ..These aspects help to clarify the amygdala's contributions to recognizing emotion from faces, to social behavior toward conspecifics, and to reward learning and instrumental behavior...
  28. pmc Intact bilateral resting-state networks in the absence of the corpus callosum
    J Michael Tyszka
    Division of Biology, California Institute of Technology, Pasadena, California 91125, USA
    J Neurosci 31:15154-62. 2011
    ..The results argue that a normal complement of resting-state networks and intact functional coupling between the hemispheres can emerge in the absence of the corpus callosum, favoring the second over the first possibility listed above...
  29. ncbi request reprint Emotional arousal in agenesis of the corpus callosum
    Lynn K Paul
    California Institute of Technology, Division of Humanities and Social Sciences, CA 91125, USA
    Int J Psychophysiol 61:47-56. 2006
    ....
  30. ncbi request reprint Agenesis of the corpus callosum: genetic, developmental and functional aspects of connectivity
    Lynn K Paul
    California Institute of Technology, MC 228 77 Pasadena, California 91125, USA
    Nat Rev Neurosci 8:287-99. 2007
    ..The study of AgCC could provide insight into the integrated cerebral functioning of healthy brains, and may offer a model for understanding certain psychiatric illnesses, such as schizophrenia and autism...
  31. ncbi request reprint Amygdala damage impairs eye contact during conversations with real people
    Michael L Spezio
    Division of the Humanities and Social Sciences, California Institute of Technology, Pasadena, California 91125, USA
    J Neurosci 27:3994-7. 2007
    ..These novel findings from real social interactions are consistent with an hypothesized role for the amygdala in autism and the approach taken here opens up new directions for quantifying social behavior in humans...
  32. ncbi request reprint Impaired judgments of sadness but not happiness following bilateral amygdala damage
    Ralph Adolphs
    University of Iowa, Iowa, USA
    J Cogn Neurosci 16:453-62. 2004
    ..The findings suggest that the amygdala's role in processing of emotional facial expressions encompasses multiple negatively valenced emotions, including fear and sadness...
  33. ncbi request reprint A mechanism for impaired fear recognition after amygdala damage
    Ralph Adolphs
    Department of Neurology, University of Iowa, Iowa City, Iowa 52242, USA
    Nature 433:68-72. 2005
    ..This finding provides a mechanism to explain the amygdala's role in fear recognition, and points to new approaches for the possible rehabilitation of patients with defective emotion perception...
  34. ncbi request reprint Preferring one taste over another without recognizing either
    Ralph Adolphs
    Department of Neurology and Neuroscience Graduate Program, The University of Iowa, 200 Hawkins Drive, Iowa City, Iowa 52242, USA
    Nat Neurosci 8:860-1. 2005
    ..The pattern of brain damage responsible for the dissociation suggests that reliable behavioral choice among tastes can occur in the absence of the gustatory cortex necessary for taste recognition...
  35. pmc Toward a neural basis for social behavior
    Damian A Stanley
    Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, CA 91125, USA Electronic address
    Neuron 80:816-26. 2013
    ....
  36. pmc The biology of fear
    Ralph Adolphs
    Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, CA 91125, USA
    Curr Biol 23:R79-93. 2013
    ..Finally, we should aim even to incorporate the conscious experience of being afraid, reinvigorating the study of feelings across species...
  37. ncbi request reprint How do we know the minds of others? Domain-specificity, simulation, and enactive social cognition
    Ralph Adolphs
    Division of Humanities and Social Sciences, California Institute of Technology, HSS 228 77, Caltech, Pasadena, CA 91125, USA
    Brain Res 1079:25-35. 2006
    ..Experiments from our own laboratory point to the amygdala as one structure that is critically involved in such processes...
  38. ncbi request reprint Neural systems responding to degrees of uncertainty in human decision-making
    Ming Hsu
    Division of Humanities and Social Sciences, 228 77, California Institute of Technology, Pasadena, CA 91125, USA
    Science 310:1680-3. 2005
    ..Neurological subjects with orbitofrontal lesions were insensitive to the level of ambiguity and risk in behavioral choices. These data suggest a general neural circuit responding to degrees of uncertainty, contrary to decision theory...
  39. pmc Dynamic construction of stimulus values in the ventromedial prefrontal cortex
    Alison Harris
    Humanities and Social Sciences, California Institute of Technology, Pasadena, California, United States of America
    PLoS ONE 6:e21074. 2011
    ....
  40. pmc Agenesis of the corpus callosum and autism: a comprehensive comparison
    Lynn K Paul
    1 California Institute of Technology, Division of Humanities and Social Sciences, Pasadena, CA, USA
    Brain 137:1813-29. 2014
    ..what are the distal causes (genetic and environmental) determining both callosal agenesis and its autistic features, and what are the proximal mechanisms by which absence of the callosum might generate autistic symptomatology? ..
  41. pmc Reduced social preferences in autism: evidence from charitable donations
    Alice Lin
    California Institute of Technology, Pasadena, CA, USA
    J Neurodev Disord 4:8. 2012
    ..abstract:..
  42. ncbi request reprint Emotion and consciousness
    Naotsugu Tsuchiya
    California Institute of Technology, HSS 228 77, Caltech, Pasadena, CA 91125, USA
    Trends Cogn Sci 11:158-67. 2007
    ..The intersection of consciousness and emotion is ripe for experimental investigation, and we outline possible examples for future studies...
  43. ncbi request reprint Amygdala damage impairs emotional memory for gist but not details of complex stimuli
    Ralph Adolphs
    Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, California 91125, USA
    Nat Neurosci 8:512-8. 2005
    ..The data support a model whereby the amygdala focuses processing resources on gist, possibly accounting for features of traumatic memories and eyewitness testimony in real life...
  44. pmc Amygdala damage eliminates monetary loss aversion
    Benedetto De Martino
    California Institute of Technology, Pasadena, CA 91125, USA
    Proc Natl Acad Sci U S A 107:3788-92. 2010
    ..The findings suggest that the amygdala plays a key role in generating loss aversion by inhibiting actions with potentially deleterious outcomes...
  45. pmc Becoming a better person: temporal remoteness biases autobiographical memories for moral events
    Jessica R Escobedo
    Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Emotion 10:511-8. 2010
    ..The effect was independent of chronological age, ethnicity, gender or personality, arguing for a general emotional bias in how we construct our moral autobiography...
  46. ncbi request reprint A framework for studying emotions across species
    David J Anderson
    Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA 91125, USA Electronic address
    Cell 157:187-200. 2014
    ....
  47. pmc Temporal isolation of neural processes underlying face preference decisions
    Hackjin Kim
    Divisions of Humanities and Social Sciences and Biology, California Institute of Technology, Pasadena, CA 91125, USA corrected
    Proc Natl Acad Sci U S A 104:18253-8. 2007
    ..The findings support a model in which rapid, automatic engagement of the NAC conveys a preference signal to the OFC, which in turn is used to guide choice...
  48. ncbi request reprint Analysis of face gaze in autism using "Bubbles"
    Michael L Spezio
    Division of Humanities and Social Sciences, California Institute of Technology, HSS 228 77, Caltech, Pasadena, CA 91125, USA
    Neuropsychologia 45:144-51. 2007
    ..The findings provide novel detail to the abnormal way in which people with autism look at faces, an impairment that likely influences all subsequent face processing...
  49. pmc Reprint of: Impaired fixation to eyes following amygdala damage arises from abnormal bottom-up attention
    Daniel P Kennedy
    Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, CA 91125, United States
    Neuropsychologia 49:589-95. 2011
    ....