Richard J Bull

Summary

Country: USA

Publications

  1. ncbi Research strategy for developing key information on bromate's mode of action
    Richard J Bull
    MoBull Consulting, 1928 Meadows Drive N, Richland, WA 99352, USA
    Toxicology 221:135-44. 2006
  2. ncbi Contribution of dichloroacetate and trichloroacetate to liver tumor induction in mice by trichloroethylene
    Richard J Bull
    Molecular Biosciences Department, Pacific Northwest National Laboratory, Richland, Washington 99352, USA
    Toxicol Appl Pharmacol 182:55-65. 2002
  3. ncbi Dichloroacetate stimulates glycogen accumulation in primary hepatocytes through an insulin-independent mechanism
    Melissa K Lingohr
    Washington State University, Pullman, Washington 99164 6510, USA
    Toxicol Sci 68:508-15. 2002
  4. doi Absorption and disposition of bromate in F344 rats
    Richard J Bull
    MoBull Consulting, Richland, WA, USA
    Toxicology 300:83-91. 2012
  5. doi Potential carcinogenic hazards of non-regulated disinfection by-products: haloquinones, halo-cyclopentene and cyclohexene derivatives, N-halamines, halonitriles, and heterocyclic amines
    Richard J Bull
    MoBull Consulting, 1928 Meadows Drive North, Richland, WA 99352, USA
    Toxicology 286:1-19. 2011
  6. doi Therapeutic dose as the point of departure in assessing potential health hazards from drugs in drinking water and recycled municipal wastewater
    Richard J Bull
    MoBull Consulting, 1928 Meadows Drive North, Richland, WA 99352, USA
    Regul Toxicol Pharmacol 60:1-19. 2011
  7. doi Chemical measures of similarity among disinfection by-product mixtures
    Richard J Bull
    MoBull Consulting, Richland, Washington 99352, USA
    J Toxicol Environ Health A 72:482-93. 2009
  8. doi Determinants of whether or not mixtures of disinfection by-products are similar
    Richard J Bull
    MoBull Consulting, Richland, Washington 99352, USA
    J Toxicol Environ Health A 72:437-60. 2009
  9. ncbi Interactions in the tumor-promoting activity of carbon tetrachloride, trichloroacetate, and dichloroacetate in the liver of male B6C3F1 mice
    Richard J Bull
    Molecular Biosciences, Pacific Northwest National Laboratory, Richland, WA 99352, USA
    Toxicology 199:169-83. 2004
  10. ncbi Development of a rat dosimetry model for bromate
    Jeff Fisher
    University of Georgia, College of Public Health, Department of Environmental Health Science, Environmental Health Science Bldg, Athens, GA 30602, USA
    Toxicology 221:235-40. 2006

Collaborators

Detail Information

Publications10

  1. ncbi Research strategy for developing key information on bromate's mode of action
    Richard J Bull
    MoBull Consulting, 1928 Meadows Drive N, Richland, WA 99352, USA
    Toxicology 221:135-44. 2006
    ....
  2. ncbi Contribution of dichloroacetate and trichloroacetate to liver tumor induction in mice by trichloroethylene
    Richard J Bull
    Molecular Biosciences Department, Pacific Northwest National Laboratory, Richland, Washington 99352, USA
    Toxicol Appl Pharmacol 182:55-65. 2002
    ..These data are not consistent with the hypothesis that all liver tumors induced by TRI were produced by TCA...
  3. ncbi Dichloroacetate stimulates glycogen accumulation in primary hepatocytes through an insulin-independent mechanism
    Melissa K Lingohr
    Washington State University, Pullman, Washington 99164 6510, USA
    Toxicol Sci 68:508-15. 2002
    ..Somewhat surprisingly, insulin-stimulated glycogenesis also appears not to involve PKB/Akt in isolated murine hepatocytes...
  4. doi Absorption and disposition of bromate in F344 rats
    Richard J Bull
    MoBull Consulting, Richland, WA, USA
    Toxicology 300:83-91. 2012
    ..This was supported by measurements of dose-dependent increases of total organic bromine (TOBr) that was eliminated in the urine. The role these organic by-products play in BrO(3)(-)-induced cancer remains to be established...
  5. doi Potential carcinogenic hazards of non-regulated disinfection by-products: haloquinones, halo-cyclopentene and cyclohexene derivatives, N-halamines, halonitriles, and heterocyclic amines
    Richard J Bull
    MoBull Consulting, 1928 Meadows Drive North, Richland, WA 99352, USA
    Toxicology 286:1-19. 2011
    ..Utilization of predictive chemical tools to guide further research can help bring resolution to the DBP issue by identifying likely DBPs with high toxicological potency...
  6. doi Therapeutic dose as the point of departure in assessing potential health hazards from drugs in drinking water and recycled municipal wastewater
    Richard J Bull
    MoBull Consulting, 1928 Meadows Drive North, Richland, WA 99352, USA
    Regul Toxicol Pharmacol 60:1-19. 2011
    ..chronic use, exposures to multiple compounds that could act in additive or synergistic ways, and the seriousness of toxicities that are observed. Aside from these considerations, a combined uncertainty factor of 1000 appeared adequate...
  7. doi Chemical measures of similarity among disinfection by-product mixtures
    Richard J Bull
    MoBull Consulting, Richland, Washington 99352, USA
    J Toxicol Environ Health A 72:482-93. 2009
    ....
  8. doi Determinants of whether or not mixtures of disinfection by-products are similar
    Richard J Bull
    MoBull Consulting, Richland, Washington 99352, USA
    J Toxicol Environ Health A 72:437-60. 2009
    ..Data suggest that further chemical characterization of DBP mixtures and more systematic study of DBP toxicology will improve the quality and usefulness of similarity criteria...
  9. ncbi Interactions in the tumor-promoting activity of carbon tetrachloride, trichloroacetate, and dichloroacetate in the liver of male B6C3F1 mice
    Richard J Bull
    Molecular Biosciences, Pacific Northwest National Laboratory, Richland, WA 99352, USA
    Toxicology 199:169-83. 2004
    ..The interactions may result in additive or inhibitory effects, but no significant evidence of synergy was observed...
  10. ncbi Development of a rat dosimetry model for bromate
    Jeff Fisher
    University of Georgia, College of Public Health, Department of Environmental Health Science, Environmental Health Science Bldg, Athens, GA 30602, USA
    Toxicology 221:235-40. 2006
    ..The proposed research is expected to be instrumental in quantifying the human health risks associated with ingestion of low levels of bromate in drinking water...