R V Rao

Summary

Affiliation: Buck Institute for Age Research
Country: USA

Publications

  1. pmc Ayurvedic medicinal plants for Alzheimer's disease: a review
    Rammohan V Rao
    The Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA 94945, USA
    Alzheimers Res Ther 4:22. 2012
  2. pmc Valosin-containing protein gene mutations: cellular phenotypes relevant to neurodegeneration
    Karen S Poksay
    The Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945, USA
    J Mol Neurosci 44:91-102. 2011
  3. pmc Coupling endoplasmic reticulum stress to the cell-death program: a novel HSP90-independent role for the small chaperone protein p23
    R V Rao
    The Buck Institute for Age Research, 8001 Redwood Blvd, Novato, CA 94945, USA
    Cell Death Differ 13:415-25. 2006
  4. ncbi request reprint Misfolded proteins, endoplasmic reticulum stress and neurodegeneration
    Rammohan V Rao
    Buck Institute for Age Research, 8001 Redwood Boulevard, Novato, California 94945 1400, USA
    Curr Opin Cell Biol 16:653-62. 2004
  5. ncbi request reprint Coupling endoplasmic reticulum stress to the cell death program
    R V Rao
    Buck Institute for Age Research, 8001 Redwood Boulevard, Novato, CA 94945, USA
    Cell Death Differ 11:372-80. 2004
  6. pmc Endoplasmic reticulum stress-induced cell death mediated by the proteasome
    L Egger
    The Buck Institute for Age Research, Novato, CA 94945, USA
    Cell Death Differ 14:1172-80. 2007
  7. ncbi request reprint Cell death in the nervous system
    Dale E Bredesen
    Buck Institute for Age Research, 8001 Redwood Boulevard, Novato, California 94945, USA
    Nature 443:796-802. 2006
  8. ncbi request reprint Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway
    Rammohan V Rao
    Buck Institute for Age Research, Novato, California 94945 and the Department of Medicine III, Johannes Gutenberg University, Mainz D 55101, Germany
    J Biol Chem 277:21836-42. 2002
  9. ncbi request reprint Double-stranded RNA-dependent protein kinase, PKR, binds preferentially to Huntington's disease (HD) transcripts and is activated in HD tissue
    A L Peel
    The Buck Institute, 8001 Redwood Boulevard, Novato, CA 94945, USA
    Hum Mol Genet 10:1531-8. 2001
  10. ncbi request reprint A ligand-receptor pair that triggers a non-apoptotic form of programmed cell death
    S Castro-Obregon
    Buck Institute for Age Research, 8001 Redwood Boulevard, Novato, CA 94945, USA
    Cell Death Differ 9:807-17. 2002

Collaborators

Detail Information

Publications17

  1. pmc Ayurvedic medicinal plants for Alzheimer's disease: a review
    Rammohan V Rao
    The Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA 94945, USA
    Alzheimers Res Ther 4:22. 2012
    ....
  2. pmc Valosin-containing protein gene mutations: cellular phenotypes relevant to neurodegeneration
    Karen S Poksay
    The Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945, USA
    J Mol Neurosci 44:91-102. 2011
    ....
  3. pmc Coupling endoplasmic reticulum stress to the cell-death program: a novel HSP90-independent role for the small chaperone protein p23
    R V Rao
    The Buck Institute for Age Research, 8001 Redwood Blvd, Novato, CA 94945, USA
    Cell Death Differ 13:415-25. 2006
    ..The results define a protective role for p23, and provide further support for a model in which ER stress is coupled to the mitochondrial intrinsic apoptotic pathway through the activities of BH3 family proteins...
  4. ncbi request reprint Misfolded proteins, endoplasmic reticulum stress and neurodegeneration
    Rammohan V Rao
    Buck Institute for Age Research, 8001 Redwood Boulevard, Novato, California 94945 1400, USA
    Curr Opin Cell Biol 16:653-62. 2004
    ..Dissecting these pathways should be valuable in understanding the pathogenesis of, and ultimately in designing therapy for, neurodegenerative diseases that feature misfolded proteins...
  5. ncbi request reprint Coupling endoplasmic reticulum stress to the cell death program
    R V Rao
    Buck Institute for Age Research, 8001 Redwood Boulevard, Novato, CA 94945, USA
    Cell Death Differ 11:372-80. 2004
    ....
  6. pmc Endoplasmic reticulum stress-induced cell death mediated by the proteasome
    L Egger
    The Buck Institute for Age Research, Novato, CA 94945, USA
    Cell Death Differ 14:1172-80. 2007
    ..Thus, the proteasome serves as a principal mediator of ER stress-induced cell death in this system...
  7. ncbi request reprint Cell death in the nervous system
    Dale E Bredesen
    Buck Institute for Age Research, 8001 Redwood Boulevard, Novato, California 94945, USA
    Nature 443:796-802. 2006
    ..Surprisingly, although the cell death itself may occur relatively late in the course of the degenerative process, the mediators of the underlying cell-death pathways have shown promise as potential therapeutic targets...
  8. ncbi request reprint Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway
    Rammohan V Rao
    Buck Institute for Age Research, Novato, California 94945 and the Department of Medicine III, Johannes Gutenberg University, Mainz D 55101, Germany
    J Biol Chem 277:21836-42. 2002
    ..Thus, ER stress-induced programmed cell death defines a novel, mitochondrial and Apaf-1-independent, intrinsic apoptotic pathway...
  9. ncbi request reprint Double-stranded RNA-dependent protein kinase, PKR, binds preferentially to Huntington's disease (HD) transcripts and is activated in HD tissue
    A L Peel
    The Buck Institute, 8001 Redwood Boulevard, Novato, CA 94945, USA
    Hum Mol Genet 10:1531-8. 2001
    ..The increased immunolocalization of the activated kinase is more pronounced in areas most affected by the disease and, coupled with the RNA binding results, suggests a role for PKR activation in the disease process...
  10. ncbi request reprint A ligand-receptor pair that triggers a non-apoptotic form of programmed cell death
    S Castro-Obregon
    Buck Institute for Age Research, 8001 Redwood Boulevard, Novato, CA 94945, USA
    Cell Death Differ 9:807-17. 2002
    ..These results argue that NK(1)R activates a death pathway different than apoptosis, and provide a signal transduction system by which to study an alternative, non-apoptotic cell death program...
  11. pmc Coupling endoplasmic reticulum stress to the cell death program in dopaminergic cells: effect of paraquat
    Shankar J Chinta
    The Buck Institute for Age Research, 8001 Redwood Blvd, Novato, CA 94945, USA
    Neuromolecular Med 10:333-42. 2008
    ..Our results indicate a protective role for p23 in PD-related programmed cell death. The data also underscore the involvement of ER, caspases, and the proteasomal system in ER stress-induced cell death process...
  12. ncbi request reprint Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation
    R V Rao
    Buck Institute for Age Research, 8001 Redwood Blvd, Novato, California 94945, USA
    J Biol Chem 276:33869-74. 2001
    ..The data underscore the involvement of ER and caspases associated with it in the ER stress-induced apoptotic process...
  13. ncbi request reprint Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78
    Rammohan V Rao
    Buck Institute for Age Research, 8001 Redwood Boulevard, Novato, CA 94945 1400, USA
    FEBS Lett 514:122-8. 2002
    ..These results define a novel protective role for GRP78 in preventing ER stress-induced cell death...
  14. pmc Endoplasmic reticulum stress-induced cell death in dopaminergic cells: effect of resveratrol
    Shankar J Chinta
    The Buck Institute for Age Research, 8001 Redwood Blvd, Novato, CA 94945, USA
    J Mol Neurosci 39:157-68. 2009
    ....
  15. ncbi request reprint Molecular components of a cell death pathway activated by endoplasmic reticulum stress
    Rammohan V Rao
    The Buck Institute for Age Research, Novato, California 94945, USA
    J Biol Chem 279:177-87. 2004
    ..Our data identify two molecules, valosin-containing protein and apoptosis-linked gene-2 (ALG-2), that appear to play a role in mediating ER stress-induced cell death...
  16. ncbi request reprint Alternative, nonapoptotic programmed cell death: mediation by arrestin 2, ERK2, and Nur77
    Susana Castro-Obregon
    Buck Institute for Age Research, Novato, California 94945 1400, USA
    J Biol Chem 279:17543-53. 2004
    ..These results suggest that Nur77, which is regulated by a MAPK pathway activated via arrestin 2, modulates NK(1)R-mediated nonapoptotic pcd...
  17. pmc Coupling endoplasmic reticulum stress to the cell death program in mouse melanoma cells: effect of curcumin
    Jason Bakhshi
    Terra Linda High School, 320 Nova Albion Way, San Rafael, CA 94903, USA
    Apoptosis 13:904-14. 2008
    ..Our studies demonstrate that curcumin triggers ER stress and the activation of specific cell death pathways that feature caspase cleavage and activation, p23 cleavage, and downregulation of the anti-apoptotic Mcl-1 protein...