- STOP using just GO: a multi-ontology hypothesis generation tool for high throughput experimentationTobias Wittkop
Buck Institute for Research on Aging, Novato, CA, USA
BMC Bioinformatics 14:53. 2013..Here, we developed and evaluated a tool for hypothesis generation from gene or protein lists using ontological concepts present in manually curated text that describes those genes and proteins...
- Collaborative software for traditional and translational researchAri E Berman
Buck Institute for Research on Aging, Bioinformatics Core, Novato, CA 94945, USA
Hum Genomics 6:21. 2012..Here, we describe formal technological requirements for such efforts and we review several software solutions that can effectively improve the organization, communication, and formalization of collaborations in biomedical research today...
- Functional organization and its implication in evolution of the human protein-protein interaction networkYiqiang Zhao
Buck Institute for Research on Aging, Novato, California, USA
BMC Genomics 13:150. 2012..The current stochastic models of evolution, however, grow the network without consideration for biological function and natural selection...