- Finding driver pathways in cancer: models and algorithmsFabio Vandin
Department of Computer Science, and Center for Computational Molecular Biology Brown University, 115 Waterman St, 4th Flr, Providence, RI 02912, USA
Algorithms Mol Biol 7:23. 2012..abstract:..
- Algorithms for detecting significantly mutated pathways in cancerFabio Vandin
Department of Computer Science, Brown University, Providence, Rhode Island, USA
J Comput Biol 18:507-22. 2011..We anticipate that our approach will find increasing use as cancer genome studies increase in size and scope...
- De novo discovery of mutated driver pathways in cancerFabio Vandin
Department of Computer Science and Center for Computational Molecular Biology, Brown University, Providence, Rhode Island 02912, USA
Genome Res 22:375-85. 2012..Our Dendrix algorithms scale to whole-genome analysis of thousands of patients and thus will prove useful for larger data sets to come from The Cancer Genome Atlas (TCGA) and other large-scale cancer genome sequencing projects...
- Ballast: a ball-based algorithm for structural motifsLu He
Department of Computer Science, Dartmouth College, Hanover, NH 03755, USA
J Comput Biol 20:137-51. 2013..By supporting generic measures of compositional and geometric similarity, Ballast provides a powerful substrate for the development of motif-matching algorithms...