Herman Vandenburgh

Summary

Affiliation: Brown University
Country: USA

Publications

  1. ncbi request reprint Space travel directly induces skeletal muscle atrophy
    H Vandenburgh
    Department of Pathology, Brown University School of Medicine and The Miriam Hospital, Providence, Rhode Island 02906, USA
    FASEB J 13:1031-8. 1999
  2. ncbi request reprint Functional assessment and tissue design of skeletal muscle
    Herman H Vandenburgh
    Brown University School of Medicine, Room 227, 164 Summitt Avenue, Providence, RI 02906, USA
    Ann N Y Acad Sci 961:201-2. 2002
  3. doi request reprint Drug-screening platform based on the contractility of tissue-engineered muscle
    Herman Vandenburgh
    Department of Pathology, RISE Research Building, Brown Medical School Miriam Hospital, Providence, RI 02906, USA
    Muscle Nerve 37:438-47. 2008
  4. pmc Automated drug screening with contractile muscle tissue engineered from dystrophic myoblasts
    Herman Vandenburgh
    Department of Pathology, Brown Medical School Miriam Hospital, Providence, Rhode Island, USA
    FASEB J 23:3325-34. 2009
  5. pmc Design and fabrication of a biodegradable, covalently crosslinked shape-memory alginate scaffold for cell and growth factor delivery
    Lin Wang
    Department of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, Rhode Island, USA
    Tissue Eng Part A 18:2000-7. 2012
  6. pmc High-content drug screening with engineered musculoskeletal tissues
    Herman Vandenburgh
    Department of Pathology, Brown Medical School Miriam Hospital, Providence, Rhode Island 02906, USA
    Tissue Eng Part B Rev 16:55-64. 2010
  7. ncbi request reprint Paracrine release of insulin-like growth factor 1 from a bioengineered tissue stimulates skeletal muscle growth in vitro
    Janet Shansky
    Department of Pathology, Brown Medical School Miriam Hospital, Providence, Rhode Island 02906, USA
    Tissue Eng 12:1833-41. 2006
  8. pmc Growth, differentiation, transplantation and survival of human skeletal myofibers on biodegradable scaffolds
    Lieven Thorrez
    Department of Pathology, Brown Medical School The Miriam Hospital, 14 Third Street, Providence, RI 02906, USA
    Biomaterials 29:75-84. 2008
  9. ncbi request reprint Mechanical stimulation improves tissue-engineered human skeletal muscle
    Courtney A Powell
    Department of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, Rhode Island 02912, USA
    Am J Physiol Cell Physiol 283:C1557-65. 2002
  10. ncbi request reprint Functional assessment of engineered tissues and elements of tissue design: breakout session summary
    Farshid Guilak
    Department of Surgery, Duke University Medical Center, Room 374 MSRB, Durham, NC 27710, USA
    Ann N Y Acad Sci 961:207-9. 2002

Research Grants

  1. Adult human skeletal muscle stem cells for functional repair
    Herman Vandenburgh; Fiscal Year: 2007
  2. High Content Screening for Muscular Dystrophy
    Herman Vandenburgh; Fiscal Year: 2007
  3. Electro-Mechanical Micro-Post Array to Detect In Vitro Muscle Contraction
    Herman Vandenburgh; Fiscal Year: 2006
  4. Vascularization of Tissue Engineered Skeletal Muscle
    Herman Vandenburgh; Fiscal Year: 2006
  5. In Vitro Matrix-Cell Interaction in Bioartificial Muscle
    Herman Vandenburgh; Fiscal Year: 2005
  6. BIOARTIFICIAL MUSCLES FOR GENE THERAPY
    Herman Vandenburgh; Fiscal Year: 2002
  7. TISSUE ENGINEERED MYOFIBERS FOR GENE THERAPY
    Herman Vandenburgh; Fiscal Year: 2001

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Space travel directly induces skeletal muscle atrophy
    H Vandenburgh
    Department of Pathology, Brown University School of Medicine and The Miriam Hospital, Providence, Rhode Island 02906, USA
    FASEB J 13:1031-8. 1999
    ..These results show for the first time that skeletal muscle fibers are directly responsive to space travel and should be a target for countermeasure development...
  2. ncbi request reprint Functional assessment and tissue design of skeletal muscle
    Herman H Vandenburgh
    Brown University School of Medicine, Room 227, 164 Summitt Avenue, Providence, RI 02906, USA
    Ann N Y Acad Sci 961:201-2. 2002
  3. doi request reprint Drug-screening platform based on the contractility of tissue-engineered muscle
    Herman Vandenburgh
    Department of Pathology, RISE Research Building, Brown Medical School Miriam Hospital, Providence, RI 02906, USA
    Muscle Nerve 37:438-47. 2008
    ..The results described in this study demonstrate the integration of tissue engineering and biomechanical testing into a single platform for the screening of compounds affecting muscle strength...
  4. pmc Automated drug screening with contractile muscle tissue engineered from dystrophic myoblasts
    Herman Vandenburgh
    Department of Pathology, Brown Medical School Miriam Hospital, Providence, Rhode Island, USA
    FASEB J 23:3325-34. 2009
    ....
  5. pmc Design and fabrication of a biodegradable, covalently crosslinked shape-memory alginate scaffold for cell and growth factor delivery
    Lin Wang
    Department of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, Rhode Island, USA
    Tissue Eng Part A 18:2000-7. 2012
    ..The compressible scaffold thus has the potential to be delivered by a minimally invasive technique, and when rehydrated in vivo with cells and/or growth factors, could serve as a temporary delivery vehicle for tissue repair...
  6. pmc High-content drug screening with engineered musculoskeletal tissues
    Herman Vandenburgh
    Department of Pathology, Brown Medical School Miriam Hospital, Providence, Rhode Island 02906, USA
    Tissue Eng Part B Rev 16:55-64. 2010
    ..Identification of compounds that improve the repair/regeneration of damaged tissues in vivo would have extensive clinical applications for treating musculoskeletal disorders...
  7. ncbi request reprint Paracrine release of insulin-like growth factor 1 from a bioengineered tissue stimulates skeletal muscle growth in vitro
    Janet Shansky
    Department of Pathology, Brown Medical School Miriam Hospital, Providence, Rhode Island 02906, USA
    Tissue Eng 12:1833-41. 2006
    ....
  8. pmc Growth, differentiation, transplantation and survival of human skeletal myofibers on biodegradable scaffolds
    Lieven Thorrez
    Department of Pathology, Brown Medical School The Miriam Hospital, 14 Third Street, Providence, RI 02906, USA
    Biomaterials 29:75-84. 2008
    ..With further improvements in cell survival, PLG scaffolds may prove useful for the implantation of primary human myofibers in future clinical applications...
  9. ncbi request reprint Mechanical stimulation improves tissue-engineered human skeletal muscle
    Courtney A Powell
    Department of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, Rhode Island 02912, USA
    Am J Physiol Cell Physiol 283:C1557-65. 2002
    ..This system allows engineering of improved skeletal muscle analogs as well as a nondestructive method to determine passive force and viscoelastic properties of the resulting tissue...
  10. ncbi request reprint Functional assessment of engineered tissues and elements of tissue design: breakout session summary
    Farshid Guilak
    Department of Surgery, Duke University Medical Center, Room 374 MSRB, Durham, NC 27710, USA
    Ann N Y Acad Sci 961:207-9. 2002
  11. ncbi request reprint Bioartificial muscles in gene therapy
    Courtney Powell
    Department of Molecular Pharmacology, Physiology and Biotechnology, Brown University, Department of Pathology, Miriam Hospital, Providence, RI, USA
    Methods Mol Med 69:219-31. 2002

Research Grants16

  1. Adult human skeletal muscle stem cells for functional repair
    Herman Vandenburgh; Fiscal Year: 2007
    ..is developing a cell-based implantation technology using bioengineered muscle tissue for both muscle damage repair and to attenuate skeletal muscle weakness which occurs from the muscle loss associated with aging. ..
  2. High Content Screening for Muscular Dystrophy
    Herman Vandenburgh; Fiscal Year: 2007
    ..While not a cure for the disease, these new drug therapies are aimed at enhancing quality and longevity of life of the DMD patient. ..
  3. Electro-Mechanical Micro-Post Array to Detect In Vitro Muscle Contraction
    Herman Vandenburgh; Fiscal Year: 2006
    ....
  4. Vascularization of Tissue Engineered Skeletal Muscle
    Herman Vandenburgh; Fiscal Year: 2006
    ..Successful completion of this project will allow the development of a reversible ex vivo gene therapy method to treat hemophilia A. ..
  5. In Vitro Matrix-Cell Interaction in Bioartificial Muscle
    Herman Vandenburgh; Fiscal Year: 2005
    ..abstract_text> ..
  6. BIOARTIFICIAL MUSCLES FOR GENE THERAPY
    Herman Vandenburgh; Fiscal Year: 2002
    ..New therapeutic treatments with recombinant proteins for chronic musculoskeletal wasting disorders will lead to enhanced quality of life and reduced costs in this 150 billion dollar annual U.S. healthcare market. ..
  7. TISSUE ENGINEERED MYOFIBERS FOR GENE THERAPY
    Herman Vandenburgh; Fiscal Year: 2001
    ..S. health care market. ..