Jay X Tang

Summary

Affiliation: Brown University
Country: USA

Publications

  1. pmc Holdfast spreading and thickening during Caulobacter crescentus attachment to surfaces
    Guanglai Li
    Physics Department, Brown University, Providence, RI 02912, USA
    BMC Microbiol 13:139. 2013
  2. ncbi request reprint Intriguing self-assembly of large granules of F-actin facilitated by gelsolin and alpha-actinin
    Jay X Tang
    Physics Department, Brown University, 184 Hope Street, Providence, Rhode Island 02912, USA
    Langmuir 21:2789-95. 2005
  3. ncbi request reprint Counterion-dependent microrheological properties of F-actin solutions across the isotropic-nematic phase transition
    Jun He
    Department of Physics, Brown University, Providence, Rhode Island 02912, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 78:011908. 2008
  4. ncbi request reprint Isotropic to nematic liquid crystalline phase transition of F-actin varies from continuous to first order
    Jorge Viamontes
    Department of Physics, Brown University, Providence, Rhode Island 02912, USA
    Phys Rev Lett 97:118103. 2006
  5. ncbi request reprint Kinetic overshoot in actin network assembly induced jointly by branching and capping proteins
    Hyeran Kang
    Physics Department, Brown University, Providence, Rhode Island 02912, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 80:041913. 2009
  6. pmc Observation and kinematic description of long actin tracks induced by spherical beads
    Hyeran Kang
    Department of Physics, Brown University, Providence, Rhode Island, USA
    Biophys J 99:2793-802. 2010
  7. ncbi request reprint Effects of osmotic force and torque on microtubule bundling and pattern formation
    Yongxing Guo
    Department of Physics, Brown University, Providence, Rhode Island 02912, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 78:041910. 2008
  8. ncbi request reprint Counterion-induced abnormal slowdown of F-actin diffusion across the isotropic-to-nematic phase transition
    Jun He
    Department of Physics, Brown University, Rhode Island 02912, USA
    Phys Rev Lett 99:068103. 2007
  9. pmc Surface contact stimulates the just-in-time deployment of bacterial adhesins
    Guanglai Li
    Physics Department, Brown University, Providence, RI 02912, USA
    Mol Microbiol 83:41-51. 2012
  10. pmc Adhesion of single bacterial cells in the micronewton range
    Peter H Tsang
    Department of Physics and Division of Engineering, Brown University, Providence, RI 02912, USA
    Proc Natl Acad Sci U S A 103:5764-8. 2006

Collaborators

Detail Information

Publications29

  1. pmc Holdfast spreading and thickening during Caulobacter crescentus attachment to surfaces
    Guanglai Li
    Physics Department, Brown University, Providence, RI 02912, USA
    BMC Microbiol 13:139. 2013
    ..Adhesion to surfaces facilitates many crucial functions of microbes in their natural habitats. Thus understanding the mechanism of microbial adhesion is of broad interest to the microbiology research community...
  2. ncbi request reprint Intriguing self-assembly of large granules of F-actin facilitated by gelsolin and alpha-actinin
    Jay X Tang
    Physics Department, Brown University, 184 Hope Street, Providence, Rhode Island 02912, USA
    Langmuir 21:2789-95. 2005
    ..Both the biochemical specificity of alpha-actinin and the thermodynamics of phase transitions are required for understanding such large scale self-assembly...
  3. ncbi request reprint Counterion-dependent microrheological properties of F-actin solutions across the isotropic-nematic phase transition
    Jun He
    Department of Physics, Brown University, Providence, Rhode Island 02912, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 78:011908. 2008
    ..In conclusion, particle tracking microrheology reveals rich rheological features of F-actin affected by the isotropic-nematic phase transition and by tuning weak electrostatic interactions among the protein filaments...
  4. ncbi request reprint Isotropic to nematic liquid crystalline phase transition of F-actin varies from continuous to first order
    Jorge Viamontes
    Department of Physics, Brown University, Providence, Rhode Island 02912, USA
    Phys Rev Lett 97:118103. 2006
    ..Tactoidal droplets of coexisting isotropic and nematic phases, differing in concentration by approximately 30%, form over the course of hours and appear to settle into near equilibrium metastable states...
  5. ncbi request reprint Kinetic overshoot in actin network assembly induced jointly by branching and capping proteins
    Hyeran Kang
    Physics Department, Brown University, Providence, Rhode Island 02912, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 80:041913. 2009
    ..These results establish a natural link between the kinetic theory of actin assembly in vitro and the cytoskeletal structure and actin dynamics in motile cells...
  6. pmc Observation and kinematic description of long actin tracks induced by spherical beads
    Hyeran Kang
    Department of Physics, Brown University, Providence, Rhode Island, USA
    Biophys J 99:2793-802. 2010
    ..Assessment of the bead rotation and its mechanistic basis offers insights into the biological function of actin-based motility...
  7. ncbi request reprint Effects of osmotic force and torque on microtubule bundling and pattern formation
    Yongxing Guo
    Department of Physics, Brown University, Providence, Rhode Island 02912, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 78:041910. 2008
    ..Similarly, we attribute the lateral contraction of the samples to osmotic torques that tend to align crossing bundles in the network...
  8. ncbi request reprint Counterion-induced abnormal slowdown of F-actin diffusion across the isotropic-to-nematic phase transition
    Jun He
    Department of Physics, Brown University, Rhode Island 02912, USA
    Phys Rev Lett 99:068103. 2007
    ....
  9. pmc Surface contact stimulates the just-in-time deployment of bacterial adhesins
    Guanglai Li
    Physics Department, Brown University, Providence, RI 02912, USA
    Mol Microbiol 83:41-51. 2012
    ..This mechanism restricts stable attachment to intimate surface interactions, thereby maximizing surface attachment, discouraging non-productive self-adherence, and preventing curing of the adhesive...
  10. pmc Adhesion of single bacterial cells in the micronewton range
    Peter H Tsang
    Department of Physics and Division of Engineering, Brown University, Providence, RI 02912, USA
    Proc Natl Acad Sci U S A 103:5764-8. 2006
    ..To our knowledge, this strength of adhesion is the strongest ever measured for biological adhesives...
  11. ncbi request reprint Growth of tactoidal droplets during the first-order isotropic to nematic phase transition of F-actin
    Patrick W Oakes
    Department of Physics, Brown University, Providence, Rhode Island 02912, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 75:061902. 2007
    ..The solution can exist in a variety of steady states near equilibrium and can be easily perturbed, settling in one prescribed by the path followed in phase space...
  12. ncbi request reprint Surface adsorption and hopping cause probe-size-dependent microrheology of actin networks
    Jun He
    Department of Physics, Brown University, Providence, Rhode Island 02912, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 83:041902. 2011
    ..Analysis of these effects is necessary in order to accurately define the actin network rheology both in vitro and in vivo...
  13. pmc Amplified effect of Brownian motion in bacterial near-surface swimming
    Guanglai Li
    Physics Department, Brown University, Providence, RI 02912, USA
    Proc Natl Acad Sci U S A 105:18355-9. 2008
    ..These results shed light on the fundamental roles of Brownian motion in microbial motility, nutrient uptake, and adhesion...
  14. pmc Fluctuation analysis of Caulobacter crescentus adhesion
    Elnaz Alipour-Assiabi
    Department of Physics and Division of Engineering, Brown University, Providence, Rhode Island, USA
    Biophys J 90:2206-12. 2006
    ..The asymmetry suggests the sequence in which the cells attach to each other, and in some cases suggests that strong crosslinks form between the stalks as they make a shared holdfast...
  15. ncbi request reprint Anionic poly(amino acid)s dissolve F-actin and DNA bundles, enhance DNase activity, and reduce the viscosity of cystic fibrosis sputum
    Jay X Tang
    Dept of Physics, Brown University, Providence, Rhode Island, USA
    Am J Physiol Lung Cell Mol Physiol 289:L599-605. 2005
    ..These findings suggest that soluble multivalent anions have potential alone or in combination with other mucolytic agents to selectively dissociate the large bundles of charged biopolymers that form in CF sputum...
  16. ncbi request reprint Accumulation of swimming bacteria near a solid surface
    Guanglai Li
    Physics Department, Brown University, Providence, Rhode Island 02912, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 84:041932. 2011
    ..Additional simulations demonstrate the dependence of accumulation on swimming speed and cell size, showing that longer and faster cells accumulate more near a surface than shorter and slower ones do...
  17. pmc Accumulation of microswimmers near a surface mediated by collision and rotational Brownian motion
    Guanglai Li
    Physics Department, Brown University, Providence, Rhode Island 02912, USA
    Phys Rev Lett 103:078101. 2009
    ..Simulations based on this model reproduce the density distributions measured for the small bacteria E. coli and Caulobacter crescentus, as well as for the much larger bull spermatozoa swimming between two walls...
  18. ncbi request reprint Orientational order parameter of the nematic liquid crystalline phase of F-actin
    Jorge Viamontes
    Department of Physics, Brown University, Providence, Rhode Island 02912, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 73:061901. 2006
    ....
  19. pmc Neutrophil morphology and migration are affected by substrate elasticity
    Patrick W Oakes
    Department of Physics, Brown University, Providence, RI, USA
    Blood 114:1387-95. 2009
    ..Finally, the phosphatidylinositol 3-kinase inhibitor LY294002 obviated the ability to sense substrate stiffness, suggesting that phosphatidylinositol 3-kinase plays a mechanistic role in neutrophil mechanosensing...
  20. pmc Molecular adsorption steers bacterial swimming at the air/water interface
    Michael Morse
    Physics Department, Brown University, Providence Rhode Island, USA
    Biophys J 105:21-8. 2013
    ..The consistent behavior of these two distinct microbial species provides insights on how microbes have evolved to cope with challenging interfacial environments...
  21. ncbi request reprint Polymerization force driven buckling of microtubule bundles determines the wavelength of patterns formed in tubulin solutions
    Yongxing Guo
    Physics Department, Brown University, Providence, RI 02912, USA
    Phys Rev Lett 98:198103. 2007
    ..The analysis implies that the bundles buckle as solid rods...
  22. ncbi request reprint Temperature effects on threshold counterion concentration to induce aggregation of fd virus
    Qi Wen
    Department of Physics, Brown University, Providence, Rhode Island 02912, USA
    Phys Rev Lett 97:048101. 2006
    ..Cc decreases exponentially as the Bjerrum length increases, suggesting that an energetic balance between the entropic effect of counterions and the counterion mediated attractive interaction gives rise to the onset of bundle formation...
  23. pmc Low flagellar motor torque and high swimming efficiency of Caulobacter crescentus swarmer cells
    Guanglai Li
    Physics Department, Brown University, Providence, Rhode Island, USA
    Biophys J 91:2726-34. 2006
    ..We derive from these results that the C. crescentus swarmer cells swim more efficiently than both E. coli and V. alginolyticus. Our findings suggest that C. crescentus is optimally adapted to low nutrient aquatic environments...
  24. ncbi request reprint Stick-slip motion and elastic coupling in crawling cells
    Alex J Loosley
    Department of Physics, Brown University, 182 Hope Street, Providence, Rhode Island 02912, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 86:031908. 2012
    ..This work highlights how the dynamical behavior of crawling cells can be derived from mechanical properties through which biochemical factors may operate to regulate cellular locomotion...
  25. pmc Relative actin nucleation promotion efficiency by WASP and WAVE proteins in endothelial cells
    Hyeran Kang
    Department of Physics, Brown University, Providence, RI 02912, USA
    Biochem Biophys Res Commun 400:661-6. 2010
    ....
  26. ncbi request reprint Single filament electrophoresis of F-actin and filamentous virus fd
    Guanglai Li
    Physics Department, Brown University, Providence, RI 02912, USA
    J Chem Phys 122:104708. 2005
    ..A reliable ratio of 1.26 is measured for fd virus to F-actin. The influence of the orientation dependent drag on electrophoretic mobility is discussed and a strategy for reliable measurement is proposed...
  27. pmc The elastic properties of the caulobacter crescentus adhesive holdfast are dependent on oligomers of N-acetylglucosamine
    Guanglai Li
    Physics Department, Brown University, Providence, RI 02912, USA
    J Bacteriol 187:257-65. 2005
    ..These results also indicate that GlcNAc polymers play an important role in the strength of the holdfast...
  28. pmc Nonmuscle myosin heavy chain IIA mediates integrin LFA-1 de-adhesion during T lymphocyte migration
    Nicole A Morin
    Department of Surgery, Rhode Island Hospital and Brown Medical School, Providence, RI 02903, USA
    J Exp Med 205:195-205. 2008
    ..Thus, during T lymphocyte migration, uropodal adhesion depends on LFA-1 avidity, where MyH9 serves as a key mechanical link between LFA-1 and the cytoskeleton that is critical for LFA-1 de-adhesion...
  29. pmc Metal ion-induced lateral aggregation of filamentous viruses fd and M13
    Jay X Tang
    Physics Department, Indiana University, Bloomington, Indiana 47405, USA
    Biophys J 83:566-81. 2002
    ..The understanding of metal ions-induced reversible aggregation based on solution electrostatics may lead to potential applications in molecular biology and medicine...