Research Topics
| Franco P PreparataSummaryAffiliation: Brown University Country: USA Publications
| Collaborators
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Detail Information
Publications
Sequencing-by-hybridization at the information-theory bound: an optimal algorithmF P Preparata
Computer Science Department, Brown University, Providence, RI 02912 1910, USA
J Comput Biol 7:621-30. 2000..Moreover, this performance is achieved while maintaining running time linear in the target sequence length...
DNA sequencing by hybridization using semi-degenerate basesFranco P Preparata
Computer Science Department, Brown University, Providence, RI 02912 1910, USA
J Comput Biol 11:753-65. 2004..While universal bases represent the ultimate goal of sequencing by hybridization, semidegenerate natural bases are the most effective known substitute...
Quick, practical selection of effective seeds for homology searchFranco P Preparata
Computer Science Department, Brown University, Providence, RI 02912 1910, USA
J Comput Biol 12:1137-52. 2005..While the challenging mathematical question of characterizing optimal search seeds remains open, we believe that our eminently efficient and effective approach represents a satisfactory solution from a practitioner's viewpoint...
Sequencing-by-hybridization revisited: the analog-spectrum proposalFranco P Preparata
Computer Science Department, Brown University, 115 Waterman Street, Providence, RI 02912 1910, USA
IEEE/ACM Trans Comput Biol Bioinform 1:46-52. 2004..One important conclusion is that accurate biochemical measurements are pivotal to the success of SBH. The theoretical proposal presented in this paper should be a convincing stimulus for the needed biotechnological work...
A novel approach to the detection of genomic approximate tandem repeats in the Levenshtein metricNevzat Onur Domaniç
Department of Computer Science, Brown University, Providence, Rhode Island 02912, USA
J Comput Biol 14:873-91. 2007..The algorithm is available at www.cs.brown.edu/people/domanic/tandem/...
Sequencing by hybridization by cooperating direct and reverse spectraSamuel A Heath
Computer Science Department, Brown University, 115 Waterman Street, Providence, RI 02912-1910, USA
J Comput Biol 10:499-508. 2003..In other words, tandem-spectrum reconstruction is the best known technique for sequencing by hybridization...
Adaptive control of hybridization noise in DNA sequencing-by-hybridizationHon Wai Leong
School of Computing, National University of Singapore, Singapore
J Bioinform Comput Biol 3:79-98. 2005..In addition, the experimental algorithmic speed-ups of the multithreshold approach are explained in terms of the interaction amongst the different threshold regimes...
Spectrum-based de novo repeat detection in genomic sequencesHuy Hoang Do
Department of Computer Science, National University of Singapore, Singapore
J Comput Biol 15:469-87. 2008..An executable program can be downloaded at http://sagri.comp.nus.edu.sg...
