Elena Oancea

Summary

Affiliation: Brown University
Country: USA

Publications

  1. doi request reprint TRPM1 forms ion channels associated with melanin content in melanocytes
    Elena Oancea
    Howard Hughes Medical Institute, Department of Cardiology, Children s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
    Sci Signal 2:ra21. 2009
  2. doi request reprint TRPM1: new trends for an old TRP
    Elena Oancea
    Department of Molecular Pharmacology, Physiology and Biotechnology, Brown University, Providence, RI, USA
    Adv Exp Med Biol 704:135-45. 2011
  3. pmc Melanosomal dynamics assessed with a live-cell fluorescent melanosomal marker
    Jan M Bruder
    Department of Molecular Pharmacology, Physiology and Biotechnology, Brown University, Providence, Rhode Island, United States of America
    PLoS ONE 7:e43465. 2012
  4. pmc UV light phototransduction activates transient receptor potential A1 ion channels in human melanocytes
    Nicholas W Bellono
    Department of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, RI 02912, USA
    Proc Natl Acad Sci U S A 110:2383-8. 2013
  5. pmc UVA phototransduction drives early melanin synthesis in human melanocytes
    Nadine L Wicks
    Department of Molecular Pharmacology, Physiology and Biotechnology, Brown University, Providence, RI 02912, USA
    Curr Biol 21:1906-11. 2011
  6. ncbi request reprint TRPC5 is a regulator of hippocampal neurite length and growth cone morphology
    Anna Greka
    Howard Hughes Medical Institute, Children s Hospital and Harvard Medical School, Enders 1309, 320 Longwood Avenue, Boston, Massachusetts 02115, USA
    Nat Neurosci 6:837-45. 2003
  7. ncbi request reprint Functional TRPM7 channels accumulate at the plasma membrane in response to fluid flow
    Elena Oancea
    Howard Hughes Medical Institute, Department of Cardiology, Children s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
    Circ Res 98:245-53. 2006
  8. ncbi request reprint Mechanism of persistent protein kinase D1 translocation and activation
    Elena Oancea
    HHMI, Children s Hospital, Harvard Medical School, 1309 Enders Building, 320 Longwood Avenue, Boston, MA 02115, USA
    Dev Cell 4:561-74. 2003

Collaborators

Detail Information

Publications8

  1. doi request reprint TRPM1 forms ion channels associated with melanin content in melanocytes
    Elena Oancea
    Howard Hughes Medical Institute, Department of Cardiology, Children s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
    Sci Signal 2:ra21. 2009
    ..We propose that TRPM1 is an ion channel whose function is critical to normal melanocyte pigmentation and is thus a potential target for pigmentation disorders...
  2. doi request reprint TRPM1: new trends for an old TRP
    Elena Oancea
    Department of Molecular Pharmacology, Physiology and Biotechnology, Brown University, Providence, RI, USA
    Adv Exp Med Biol 704:135-45. 2011
    ..This review will summarize and discuss our present knowledge of TRPM1: its discovery, expression, regulation, and proposed functions in skin and eye...
  3. pmc Melanosomal dynamics assessed with a live-cell fluorescent melanosomal marker
    Jan M Bruder
    Department of Molecular Pharmacology, Physiology and Biotechnology, Brown University, Providence, Rhode Island, United States of America
    PLoS ONE 7:e43465. 2012
    ....
  4. pmc UV light phototransduction activates transient receptor potential A1 ion channels in human melanocytes
    Nicholas W Bellono
    Department of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, RI 02912, USA
    Proc Natl Acad Sci U S A 110:2383-8. 2013
    ..Our results show that TRPA1 is essential for a unique extraocular phototransduction pathway in human melanocytes that is activated by physiological doses of UVR and results in early melanin synthesis...
  5. pmc UVA phototransduction drives early melanin synthesis in human melanocytes
    Nadine L Wicks
    Department of Molecular Pharmacology, Physiology and Biotechnology, Brown University, Providence, RI 02912, USA
    Curr Biol 21:1906-11. 2011
    ..Our findings identify a novel UVA-sensitive signaling pathway in melanocytes that leads to calcium mobilization and melanin synthesis and may underlie the mechanism of IPD in human skin...
  6. ncbi request reprint TRPC5 is a regulator of hippocampal neurite length and growth cone morphology
    Anna Greka
    Howard Hughes Medical Institute, Children s Hospital and Harvard Medical School, Enders 1309, 320 Longwood Avenue, Boston, Massachusetts 02115, USA
    Nat Neurosci 6:837-45. 2003
    ..Dominant-negative TRPC5 expression allowed significantly longer neurites and filopodia to form. We conclude that TRPC5 channels are important components of the mechanism controlling neurite extension and growth cone morphology...
  7. ncbi request reprint Functional TRPM7 channels accumulate at the plasma membrane in response to fluid flow
    Elena Oancea
    Howard Hughes Medical Institute, Department of Cardiology, Children s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
    Circ Res 98:245-53. 2006
    ..In vascular smooth muscle cells, but not in several types of endothelial cells, fluid flow increased endogenous native TRPM7 current amplitude. We hypothesize that TRPM7 plays a role in pathological response to vessel wall injury...
  8. ncbi request reprint Mechanism of persistent protein kinase D1 translocation and activation
    Elena Oancea
    HHMI, Children s Hospital, Harvard Medical School, 1309 Enders Building, 320 Longwood Avenue, Boston, MA 02115, USA
    Dev Cell 4:561-74. 2003
    ..We incorporate the kinetics of PKD1 translocation into a three-state model that suggests how PKD1 binding to DAG and Galphaq uniquely encodes frequency-dependent PKD1 signaling...