Eric M Morrow

Summary

Affiliation: Brown University
Country: USA

Publications

  1. pmc Clinical characteristics of children with autism spectrum disorder and co-occurring epilepsy
    Emma W Viscidi
    Department of Epidemiology, Division of Biology and Medicine, Brown University, Providence, Rhode Island, United States of America
    PLoS ONE 8:e67797. 2013
  2. pmc DELISHUS: an efficient and exact algorithm for genome-wide detection of deletion polymorphism in autism
    Derek Aguiar
    Department of Computer Science, Center for Computational Molecular Biology, Brown University, Providence, RI, USA
    Bioinformatics 28:i154-62. 2012
  3. pmc Lighting a path: genetic studies pinpoint neurodevelopmental mechanisms in autism and related disorders
    Matthew F Pescosolido
    Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI 02912, USA
    Dialogues Clin Neurosci 14:239-52. 2012
  4. pmc Common genetic variants, acting additively, are a major source of risk for autism
    Lambertus Klei
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Mol Autism 3:9. 2012
  5. pmc Genomic copy number variation in disorders of cognitive development
    Eric M Morrow
    Brown University and Developmental Disorders Genetics Research Program, Emma Pendleton Bradley Hospital, Providence, RI, USA
    J Am Acad Child Adolesc Psychiatry 49:1091-104. 2010
  6. pmc Intellectual disability is associated with increased runs of homozygosity in simplex autism
    Ece D Gamsiz
    Laboratory for Molecular Medicine, Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, 70 Ship Street, Providence, RI 02912, USA
    Am J Hum Genet 93:103-9. 2013
  7. pmc Distribution of disease-associated copy number variants across distinct disorders of cognitive development
    Matthew F Pescosolido
    Institute for Brain Science at Brown University, Providence, RI 02912, USA
    J Am Acad Child Adolesc Psychiatry 52:414-430.e14. 2013
  8. pmc An unbalanced translocation involving loss of 10q26.2 and gain of 11q25 in a pedigree with autism spectrum disorder and cerebellar juvenile pilocytic astrocytoma
    Hassan M Minhas
    Developmental Disorders Genetics Research Program, Emma Pendleton Bradley Hospital, The Warren Alpert Medical School of Brown University, Providence, RI 02912, USA
    Am J Med Genet A 161:787-91. 2013
  9. pmc Christianson syndrome protein NHE6 modulates TrkB endosomal signaling required for neuronal circuit development
    Qing Ouyang
    Departments of Molecular Biology, Cell Biology and Biochemistry and Institute for Brain Science, Brown University, Laboratory for Molecular Medicine, 70 Ship Street, Providence, RI 02903, USA
    Neuron 80:97-112. 2013
  10. doi request reprint A novel familial 11p15.4 microduplication associated with intellectual disability, dysmorphic features, and obesity with involvement of the ZNF214 gene
    Elvera Sofos
    Alpert Medical School of Brown University, Providence, Rhode Island, USA
    Am J Med Genet A 158:50-8. 2012

Collaborators

  • Sorin Istrail
  • Shelly Gunn
  • Bernie Devlin
  • Robert M Joseph
  • Sarah J Spence
  • Daniel H Geschwind
  • Matthew F Pescosolido
  • Ece D Gamsiz
  • Emma W Viscidi
  • Shailender Nagpal
  • Hassan M Minhas
  • Michael Schmidt
  • Qing Ouyang
  • Elizabeth W Triche
  • Stephan J Sanders
  • Unikora Yang
  • Matthew W State
  • Michael T Murtha
  • Edwin H Cook
  • Derek Aguiar
  • Elvera Sofos
  • Lambertus Klei
  • Justyna Piasecka
  • John Gaitanis
  • Sofia B Lizarraga
  • Debra Ellisor
  • Rebecca L McLean
  • Matthew Schwede
  • Jingyi Gong
  • Abbie M Frederick
  • Julie A Kauer
  • Umadevi Tantravahi
  • Vanessa Hus
  • Christopher A Walsh
  • Jose B Quintos
  • A Jeremy Willsey
  • Nadine M Melhem
  • Timothy W Yu
  • Catherine Lord
  • Dorothy E Grice
  • Kathryn Roeder
  • David H Ledbetter
  • Karine Hovanes
  • Donna M Martin
  • Shrikant M Mane
  • Bjarni V Halldorsson
  • Christa Lese Martin
  • Daniel Moreno-De-Luca
  • Mark Sabbagh
  • Pauline Chaste
  • Dianne Abuelo
  • James S Sutcliffe
  • Natasha Shur
  • Eric Fombonne
  • Jennifer K Lowe

Detail Information

Publications11

  1. pmc Clinical characteristics of children with autism spectrum disorder and co-occurring epilepsy
    Emma W Viscidi
    Department of Epidemiology, Division of Biology and Medicine, Brown University, Providence, Rhode Island, United States of America
    PLoS ONE 8:e67797. 2013
    ..To estimate the prevalence of epilepsy in children with Autism Spectrum Disorder (ASD) and to determine the demographic and clinical characteristics of children with ASD and epilepsy in a large patient population...
  2. pmc DELISHUS: an efficient and exact algorithm for genome-wide detection of deletion polymorphism in autism
    Derek Aguiar
    Department of Computer Science, Center for Computational Molecular Biology, Brown University, Providence, RI, USA
    Bioinformatics 28:i154-62. 2012
    ..Identifying the genetic heterogeneity of small deletions remains a major unresolved computational problem partly due to the inability of algorithms to detect them...
  3. pmc Lighting a path: genetic studies pinpoint neurodevelopmental mechanisms in autism and related disorders
    Matthew F Pescosolido
    Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI 02912, USA
    Dialogues Clin Neurosci 14:239-52. 2012
    ..While there are many genetic mutations involved, novel treatments may need to target only one of few developmental mechanisms...
  4. pmc Common genetic variants, acting additively, are a major source of risk for autism
    Lambertus Klei
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Mol Autism 3:9. 2012
    ..abstract:..
  5. pmc Genomic copy number variation in disorders of cognitive development
    Eric M Morrow
    Brown University and Developmental Disorders Genetics Research Program, Emma Pendleton Bradley Hospital, Providence, RI, USA
    J Am Acad Child Adolesc Psychiatry 49:1091-104. 2010
    ..To emphasize new principles emerging from this area, involving the genetic architecture of disease, pathophysiology, and diagnosis...
  6. pmc Intellectual disability is associated with increased runs of homozygosity in simplex autism
    Ece D Gamsiz
    Laboratory for Molecular Medicine, Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, 70 Ship Street, Providence, RI 02912, USA
    Am J Hum Genet 93:103-9. 2013
    ..In summary, our data suggest a distinct genetic architecture for participants with autism and co-occurring intellectual disability and that this architecture could involve a role for recessively inherited loci for this autism subgroup. ..
  7. pmc Distribution of disease-associated copy number variants across distinct disorders of cognitive development
    Matthew F Pescosolido
    Institute for Brain Science at Brown University, Providence, RI 02912, USA
    J Am Acad Child Adolesc Psychiatry 52:414-430.e14. 2013
    ..We also sought to identify gene mechanisms common to groups of diagnoses and/or specific to a given diagnosis based on associations with CNVs...
  8. pmc An unbalanced translocation involving loss of 10q26.2 and gain of 11q25 in a pedigree with autism spectrum disorder and cerebellar juvenile pilocytic astrocytoma
    Hassan M Minhas
    Developmental Disorders Genetics Research Program, Emma Pendleton Bradley Hospital, The Warren Alpert Medical School of Brown University, Providence, RI 02912, USA
    Am J Med Genet A 161:787-91. 2013
    ..Together these data support a role for NTM and OPCML in developmental delay and potentially in cancer susceptibility...
  9. pmc Christianson syndrome protein NHE6 modulates TrkB endosomal signaling required for neuronal circuit development
    Qing Ouyang
    Departments of Molecular Biology, Cell Biology and Biochemistry and Institute for Brain Science, Brown University, Laboratory for Molecular Medicine, 70 Ship Street, Providence, RI 02903, USA
    Neuron 80:97-112. 2013
    ..Finally, exogenous BDNF rescues defects in neuronal arborization. We propose that NHE6 mutation leads to circuit defects that are in part due to impoverished neuronal arborization that may be treatable by enhanced TrkB signaling...
  10. doi request reprint A novel familial 11p15.4 microduplication associated with intellectual disability, dysmorphic features, and obesity with involvement of the ZNF214 gene
    Elvera Sofos
    Alpert Medical School of Brown University, Providence, Rhode Island, USA
    Am J Med Genet A 158:50-8. 2012
    ..2000]. This three-generation pedigree outlines features of a novel microduplication syndrome...